The purpose of this study was to investigate the relation between self concept and depression of middle-age women. Data were collected by a questionnaire from June 23 to July 3, 1997. The subject for this study were 138 women between 40-60 years of age living in Seoul and Incheon. The instruments used for this study were the self concept scale developed by Rosenberg and Choi, Jung-Hun and the depression scale developed by Rockliff and the investigator. The data were analyzed by descriptive statistics, t-test, ANOVA, Pearson correlation coefficient, stepwise multiple regression using the SPSS program. The results of this study were as follows 1. Mean score of self concept was 3.58, in minimum score 2.86 to maximum score 3.99.2. Mean score of depression scale was 1.95, in a minimum score 1.50 to maximum score 2.61.3. The relationship between self concept and depression was statistically significant negative correlation(r=-0.5121, p<0.001).4. General characteristics variables significantly related to the level of self concept were marital status(t=-3.22, p<0.01), experience of disease in a year(t=2.76, p<0.01), child problem(t=-2.59, p<0.05), marital satisfaction(F=6.80, p<0.05).5. General characteristics variables significantly related to the level of depression were possession of house(t=-2.42, p<0.01), experience of disease in a year(t=-4.32, p<0.001), child problem(t=3.12, p<0.05), husband problem(t=5.29, p<0.001), marital satisfaction (F=8.36, p<0.001).6. Obstetrical characteristics variables significantly related to the level of self concept was times of pregnancy(F=3.54, p<0.05).7. Obstetrical characteristics variables significantly related to the level of depression were age of menarche(F=3.87, p<0.05), times of abortion(F=2.49, p<0.01) number of children(F=3.36, p<0.01).8. In the stepwise multiple regression analysis, the main influencing variables on depression of middle aged women were self concept(R2=.26, p<0.001), husband problem (R2=.37, p<0.001), experience of disease in a year(R2=.41, p<0.001) and possession of house(R2=.44, p<0.001).