AbstractThe purpose of this study is to examine the magnetohydrodynamic mixed convection Casson fluid flow over an inclined flat plate along with the heat source/sink. The present flow problem is considered under the assumption of the chemical reaction and thermal radiation impacts along with heat and mass transport. The leading nonlinear partial differential equations of the flow problem were renovated into the nonlinear ordinary differential equations (ODEs) with the assistance of appropriate similarity transformations and then we solved these ODEs with the employment of the bvp4c technique using the computational software MATLAB. The consequences of numerous leading parameters such as thermophoretic parameter, local temperature Grashof number, solutal Grashof number, suction parameter, magnetic field parameter, Prandtl number, chemical reaction parameter, Dufour number, Soret number, angle of inclination, radiation parameter, heat source/sink, and Casson parameter on the fluid velocity, temperature, and concentration profiles are discoursed upon and presented through different graphs. Some important key findings of the present investigation are that the temperature of the Casson fluid becomes lower for local temperature Grashof number and solutal Grashof number. It is initiated that the Casson fluid parameter increases the velocity of the fluid whereas the opposite effect is noticed in the temperature profile. Higher estimation of Prandtl number and magnetic parameter elevated the Casson fluid concentration. Finally, the skin friction coefficient, Nusselt number, and Sherwood number are calculated and tabulated. It is also examined that the Nusselt number is weakened for both the Dufour number and Soret number but the skin fraction coefficient is greater for both the Dufour number and Soret number.