Z-pinch implosions driven by the SATURN device [D. D. Bloomquist et al., Proceedings of the 6th Institute of Electrical and Electronics Engineers (IEEE) Pulsed Power Conference, Arlington, VA, edited by P. J. Turchi and B. H. Bernstein (IEEE, New York, 1987), p. 310] at Sandia National Laboratory are modeled with a two-dimensional radiation magnetohydrodynamic (MHD) code, showing strong growth of the magneto-Rayleigh–Taylor (MRT) instability. Modeling of the linear and nonlinear development of MRT modes predicts growth of bubble-spike structures that increase the time span of stagnation and the resulting x-ray pulse width. Radiation is important in the pinch dynamics, keeping the sheath relatively cool during the run-in and releasing most of the stagnation energy. The calculations give x-ray pulse widths and magnitudes in reasonable agreement with experiments, but predict a radiating region that is too dense and radially localized at stagnation. We also consider peaked initial density profiles with constant imploding sheath velocity that should reduce MRT instability and improve performance. Krypton simulations show an output x-ray power ≳80 TW for the peaked profile.