Magnetic Resonance In Chemistry Research Articles

Parahydrogen-Induced Polarization Relayed via Proton Exchange.

The hyperpolarization of nuclear spins is a game-changing technology that enables hitherto inaccessible applications for magnetic resonance in chemistry and biomedicine. Despite significant advances and discoveries in the past, however, the quest to establish efficient and effective hyperpolarization methods continues. Here, we describe a new method that combines the advantages of direct parahydrogenation, high polarization (P), fast reaction, and low cost with the broad applicability of polarization transfer via proton exchange. We identified the system propargyl alcohol + pH2 → allyl alcohol to yield 1H polarization in excess of P ≈ 13% by using only 50% enriched pH2 at a pressure of ≈1 bar. The polarization was then successfully relayed via proton exchange from allyl alcohol to various target molecules. The polarizations of water and alcohols (as target molecules) approached P ≈ 1% even at high molar concentrations of 100 mM. Lactate, glucose, and pyruvic acid were also polarized, but to a lesser extent. Several potential improvements of the methodology are discussed. Thus, the parahydrogen-induced hyperpolarization relayed via proton exchange (PHIP-X) is a promising approach to polarize numerous molecules which participate in proton exchange and support new applications for magnetic resonance.

How to write a research article for MRC

This nonscientific tutorial proposes best practice for authors publishing research articles in Magnetic Resonance in Chemistry (MRC). It offers authors essential insights into writing eye-catching article titles, author/co-author names and hierarchy, IMRaD and IRDaM article structures, referencing and the composition of abstracts, introductions, experimental, results and discussion, and conclusions together with the all-important covering letter. This arsenal of insights aims to provide tools for authors to maximize the chance of success for their research articles.

Computational 1H NMR: Part 1. Theoretical background

This is the first of three closely interrelated reviews prepared for Magnetic Resonance in Chemistry dealing accordingly with theoretical background, chemical applications, and biochemical studies by means of computational 1H NMR. Presented in the first part of the review is a general outline of the modern theoretical methods and accuracy factors of computational 1H NMR involving locally dense basis set schemes, solvent effects, vibrational corrections, and relativistic effects performed at the DFT and/or nonempirical levels. This review is dedicated to Professor Stephan Sauer in view of his invaluable contribution to the field of computational NMR.

Computational 1 H NMR: Part 2. Chemical applications.

This is the second one of three closely interrelated reviews dealing with computation of 1 H NMR chemical shifts and 1 H-1 H spin-spin coupling constants prepared for Magnetic Resonance in Chemistry. Presented in this review are some basic notes and illustrative examples of how modern computational 1 H NMR could be used for structural elucidation and stereoelectronic studies of the medium-sized organic molecules involving saturated, unsaturated, aromatic, and heteroaromatic compounds together with their functional derivatives and coordination complexes to get deeper insight into their stereochemical structure and stereodynamic behavior.

Computational 1H NMR: Part 1. Theoretical background

This is the first one of the three closely interrelated reviews to be published in Magnetic Resonance in Chemistry dealing with accordingly theoretical background, chemical applications, and biochemical studies of and by means of computational 1 H NMR. Presented in the first part of the review is a general outline of the modern theoretical methods and accuracy factors of computational 1 H NMR involving locally dense basis set schemes, solvent effects, vibrational corrections, and relativistic effects performed at the density functional theory and/or nonempirical levels. This review is dedicated to Prof. Stephan Sauer in view of his invaluable contribution to the field of computational nuclear magnetic resonance.

Stability Enhancement of 129Xe Hyperpolarizing System Using Alkali Metal Vapor in Spin-Exchange Optical Pumping Cell to Achieve High NMR Sensitivity.

Hyperpolarized (HP) 129Xe NMR and MRI have enabled 129Xe studies with extraordinarily enhanced sensitivity, stimulating new developments in magnetic resonance in chemistry, physics, biology and medicine. However, the standard method of HP 129Xe production inevitably demands Rb vapor for the excitation, which has made the method very sensitive to impurities such as water or oxygen. This is the case especially in the recirculating system. In the present study, stability of the hyperpolarizing system is discussed by proposing the "cell decay constant", which symbolizes the decay rate of the NMR signal obtained from the system. The cell decay constant is effectively decreased to 1/3 by introducing separated chambers and mechanical stirring of the alkali metals used in the system, making it effective for accumulating FIDs over 30 to 100 h. The newly developed hyperpolarizing system has been successfully applied for newly detecting a broad signal at 190 ppm with an industrial material Nanofiber.

Assessing 2D electrophoretic mobility spectroscopy (2D MOSY) for analytical applications.

Electrophoretic displacement of charged entity phase modulates the spectrum acquired in electrophoretic NMR experiments, and this modulation can be presented via 2D FT as 2D mobility spectroscopy (MOSY) spectra. We compare in various mixed solutions the chemical selectivity provided by 2D MOSY spectra with that provided by 2D diffusion‐ordered spectroscopy (DOSY) spectra and demonstrate, under the conditions explored, a superior performance of the former method. 2D MOSY compares also favourably with closely related LC‐NMR methods. The shape of 2D MOSY spectra in complex mixtures is strongly modulated by the pH of the sample, a feature that has potential for areas such as in drug discovery and metabolomics. Copyright © 2016 The Authors. Magnetic Resonance in Chemistry published by John Wiley & Sons Ltd.

Perspectives on hyperpolarised solution‐state magnetic resonance in chemistry

This perspective article reviews some of the recent developments in the field of hyperpolarisation, with a focus on solution-state NMR spectroscopy of small molecules. Two techniques are considered in more detail, dissolution dynamic nuclear polarisation (D-DNP) and signal amplification by reversible exchange (SABRE). Some of the opportunities and challenges for applications of hyperpolarised solution-state magnetic resonance in chemistry are discussed. Copyright © 2016 John Wiley & Sons, Ltd.

NMR pioneers reflect on Silicon Valley: a conversation with Martin Packard and Weston Anderson.

NMR pioneers reflect on Silicon Valley: a conversation with Martin Packard and Weston Anderson.

Matrix-assisted diffusion-ordered spectroscopy: choosing a matrix.

Diffusion‐ordered spectroscopy (DOSY) is an important technique for separating the NMR signals of the components in a mixture, and relies on differences in diffusion coefficient. Standard DOSY experiments therefore struggle when the components of a mixture are of similar size, and hence diffuse at similar rates. Fortunately, the diffusion coefficients of solutes can be manipulated by changing the matrix in which they diffuse, using matrix components that interact differentially with them, a technique known as matrix‐assisted DOSY. In the present investigation, we evaluate the performance of a number of new, previously used, and mixed matrices with an informative test mixture: the three positional isomers of dihydroxybenzene. The aim of this work is to present the matrix‐assisted DOSY user with information about the potential utility of a set of matrices (and combinations of matrices), including ionic and non‐ionic surfactants, complexing agents, polymers, and mixed solvents. A variety of matrices improved the diffusion resolution of the signals of the test system, with the best separation achieved by mixed micelles of sodium dodecyl sulfate and cetyl trimethylammonium bromide. The use of mixed matrices offers great potential for the analyst to tailor the matrix to a particular sample under study. © 2016 The Authors Magnetic Resonance in Chemistry Published by John Wiley & Sons, Ltd.

High-resolution magic angle spinning (1) H NMR measurement of ligand concentration in solvent-saturated chromatographic beads.

A method based on 1H high‐resolution magic angle spinning NMR has been developed for measuring concentration accurately in heterogeneous materials like that of ligands in chromatography media. Ligand concentration is obtained by relating the peak integrals for a butyl ligand in the spectrum of a water‐saturated chromatography medium to the integral of the added internal reference. The method is fast, with capacity of 10 min total sample preparation and analysis time per sample; precise, with a reproducibility expressed as 1.7% relative standard deviation; and accurate, as indicated by the excellent agreement of derived concentration with that obtained previously by 13C single‐pulse excitation MAS NMR. The effects of radiofrequency field inhomogeneity, spin rate, temperature increase due to spinning, and distribution and re‐distribution of medium and reference solvent both inside the rotor during spinning and between bulk solvent and pore space are discussed in detail. © 2016 The Authors Magnetic Resonance in Chemistry published by John Wiley & Sons Ltd.

NMR characterization of novel pyranoanthocyanins derived from the pulp of Panax quinquefolius L. (North American ginseng).

Three major pigments (one natural and two derived) were determined to be present in the berry pulp of Panax quinquefolius L. (North American ginseng). The first was a simple anthocyanin (pelargonidin 3-O-lathyroside) along with two novel pyranoanthocyanins, structurally similar to those recently discovered in Staghorn sumac. The three anthocyanins were structurally characterized using NMR (1 H, gCOSY, gHSQC, gHMBC, TOCSY, ROESY, and 13 C DEPTq135) and High Resolution MS. All three anthocyanins had the disaccharide lathyrose (2-O-(β-D-xylopyranosyl)-β-D-galactopyranoside) attached at the 3-O position. In the tradition of naming novel anthocyanin aglycones based on botanical origin, the new pyranoanthocyanin aglycones have been given the common names Panaxidin A (pelaragonidin-4-vinylcatechol) and Panaxidin B (pelargonidin-4-vinylphenol). Copyright © 2015 Her Majesty the Queen in Right of Canada Magnetic Resonance in Chemistry © 2015 John Wiley & Sons, Ltd.

Investigation of chloromethane complexes of cryptophane-A analogue with butoxy groups using ¹³C NMR in the solid state and solution along with single crystal X-ray diffraction.

Host‐guest complexes between cryptophane‐A analogue with butoxy groups (cryptophane‐But) and chloromethanes (chloroform, dichloromethane) were investigated in the solid state by means of magic‐angle spinning 13C NMR spectroscopy. The separated local fields method with 13C‐1H dipolar recoupling was used to determine the residual dipolar coupling for the guest molecules encaged in the host cavity. In the case of chloroform guest, the residual dipolar interaction was estimated to be about 19 kHz, consistent with a strongly restricted mobility of the guest in the cavity, while no residual interaction was observed for encaged dichloromethane. In order to rationalize this unexpected result, we performed single crystal X‐ray diffraction studies, which confirmed that both guest molecules indeed were present inside the cryptophane cavity, with a certain level of disorder. To improve the insight in the dynamics, we performed a 13C NMR spin‐lattice relaxation study for the dichloromethane guest in solution. The system was characterized by chemical exchange, which was slow on the chemical shift time scale but fast with respect to the relaxation rates. Despite these disadvantageous conditions, we demonstrated that the data could be analyzed and that the results were consistent with an isotropic reorientation of dichloromethane within the cryptophane cavity. Copyright © 2015 The Authors. Magnetic Resonance in Chemistry published by John Wiley & Sons Ltd.

¹³C SPE MAS measurement of ligand concentration in compressible chromatographic beads.

A method for measuring the ligand concentration in heterogeneous materials like chromatography media is described. In this method, 13C single pulse excitation magic angle spinning NMR experiment with broadband 1H decoupling is used to determine the peak integrals for a butyl ligand in the spectrum of a dried chromatography medium. Within a carefully controlled protocol, those integrals compared with that of the internal reference compound dimethyl sulfone provide the required volume concentration with an accuracy of ca 2%. The effects of temperature, degree of hydration, and other experimental parameters are discussed. Copyright © 2015 The Authors. Magnetic Resonance in Chemistry published by John Wiley & Sons Ltd.

1H and 13C NMR assignments of two new piperazine‐trione from the fungus Penicillium crustosum YN‐HT‐15

Magnetic Resonance in ChemistryVolume 53, Issue 8 p. 620-623 Letter - spectral assignments 1H and 13C NMR assignments of two new piperazine-trione from the fungus Penicillium crustosum YN-HT-15 Haifeng Wang, Haifeng Wang School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorGang Chen, Gang Chen School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorYanping Liu, Yanping Liu School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorHuiming Hua, Huiming Hua School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorJiao Bai, Jiao Bai School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorYue-Hu Pei, Corresponding Author Yue-Hu Pei School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaCorrespondence to: Yue-Hu Pei, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China. E-mail: peiyueh@vip.163.comSearch for more papers by this author Haifeng Wang, Haifeng Wang School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorGang Chen, Gang Chen School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorYanping Liu, Yanping Liu School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorHuiming Hua, Huiming Hua School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorJiao Bai, Jiao Bai School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaSearch for more papers by this authorYue-Hu Pei, Corresponding Author Yue-Hu Pei School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang, 110016 China Key Laboratory of Structure-based Drug Design and Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, 110016 ChinaCorrespondence to: Yue-Hu Pei, School of Traditional Chinese Materia Medica, Shenyang Pharmaceutical University, Shenyang 110016, China. E-mail: peiyueh@vip.163.comSearch for more papers by this author First published: 27 May 2015 https://doi.org/10.1002/mrc.4256Citations: 6Read the full textAboutRelatedInformationPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessClose modalShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Citing Literature Volume53, Issue8August 2015Pages 620-623 RelatedInformation RecommendedStereochemical analysis and complete 1H/13C NMR chemical shift assignments of matrine. Application of NOE and two-dimensional NMR techniquesNina C. Gonnella, Jen Chen, Magnetic Resonance in Chemistry13C NMR assignments of brassinosteroids by two-dimensional techniquesTetsu Ando, Masakazu Aburatani, Nozomu Koseki, Seiichi Asakawa, Takehito Mouri, Hiroshi Abe, Magnetic Resonance in ChemistryComplete 1H and 13C NMR assignments of aurasperone A and fonsecinone A, two bis-naphthopyrones produced by Aspergillus aculeatusFrancinete Ramos Campos, Andersson Barison, Cristina Daolio, Antonio G. Ferreira, Edson Rodrigues-Fo, Magnetic Resonance in ChemistryStructure elucidation of cyanidin-3-sambubioside and assignments of the 1H and 13C NMR resonances through two-dimensional shift-correlated NMR techniquesØyvind M. Andersen, Dagfinn W. Aksnes, Willy Nerdal, Ole-P. Johansen, Phytochemical AnalysisAlgal carotenoids 47–NMR study of all-trans-peridinin, including complete 1H and 13C NMR assignmentsJostein Krane, Torunn Aakermann, Synnøve Liaaen-Jensen, Magnetic Resonance in Chemistry

Probing signal amplification by reversible exchange using an NMR flow system.

Hyperpolarization methods are used in NMR to overcome its inherent sensitivity problem. Herein, the biologically relevant target nicotinamide is polarized by the hyperpolarization technique signal amplification by reversible exchange. We illustrate how the polarization transfer field, and the concentrations of parahydrogen, the polarization-transfer-catalyst and substrate can be used to maximize signal amplification by reversible exchange effectiveness by reference to the first-order spin system of this target. The catalyst is shown to be crucial in this process, first by facilitating the transfer of hyperpolarization from parahydrogen to nicotinamide and then by depleting the resulting polarized states through further interaction. The 15 longitudinal one, two, three and four spin order terms produced are rigorously identified and quantified using an automated flow apparatus in conjunction with NMR pulse sequences based on the only parahydrogen spectroscopy protocol. The rates of build-up of these terms were shown to follow the order four∼three > two > single spin; this order parallels their rates of relaxation. The result of these competing effects is that the less-efficiently formed single-spin order terms dominate at the point of measurement with the two-spin terms having amplitudes that are an order of magnitude lower. We also complete further measurements to demonstrate that 13C NMR spectra can be readily collected where the long-lived quaternary 13C signals appear with significant intensity. These are improved upon by using INEPT. In summary, we dissect the complexity of this method, highlighting its benefits to the NMR community and its applicability for high-sensitivity magnetic resonance imaging detection in the future. © 2014 The Authors. Magnetic Resonance in Chemistry by John Wiley & Sons, Ltd.

MRC the new Magnetic Resonance in Chemistry

Magnetic Resonance in ChemistryVolume 52, Issue 1-2 p. 1-2 Editorial MRC the new Magnetic Resonance in Chemistry First published: 28 November 2013 https://doi.org/10.1002/mrc.4033Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat No abstract is available for this article. Volume52, Issue1-2January-February 2014Pages 1-2 RelatedInformation

MRC special issue on NMR of small molecules in anisotropic media

It was a great pleasure to edit and even a greater one to present this special issue to the readers of Magnetic Resonance in Chemistry. The relatively recent developments of weak alignment media compatible with organic solvents have opened new avenues on the structural analysis of complex natural and synthetic small organic molecules by NMR spectroscopy.1 The first NMR experiment of a small molecule in anisotropic media was performed by Saupe and Englert in 1963, in which benzene was partially aligned in the nematic phase of p-azoxyanisole.2 This experiment led to the later development of the theory of alignment3 and also permitted the empirical determination of the chemical shielding anisotropy of the benzene ring. The strong degree of alignment induced by nematic liquid crystal prevented their practical application to the structural analysis of complex small organic molecules. However, NMR spectroscopy of liquid crystals developed itself into a strong field of research and applications. This topic is outside the scope of this special issue. Weak alignment was first introduced by Tjandra and Bax in 1997 as a new and powerful tool for the study of the structure and dynamics of proteins.4 Its application quickly extended to the analysis of nucleic acids, and several alignment media compatible with water were developed since then. However, small organic molecules had to wait nearly 40 years to be analyzed by NMR in weak alignment media compatible with organic solvents. The deuterium quadrupolar coupling and the dipolar coupling are anisotropic NMR parameters not observable in conventional liquid state NMR experiments, but save for relaxation effects, they can be revealed when molecules are exposed to orienting media. Residual dipolar couplings (RDCs) have proven to be very powerful for the constitutional, configurational, and conformational analysis of small molecules,1 as a complementary tool to existing NMR parameters used for the same purpose, e.g. NOE and the J-based analysis. For certain compounds, the use of only these two existing NMR parameters leads to more than one solution structure, and this ambiguity can be lifted if RDCs are added to the analysis. The residual deuterium quadrupolar coupling has been extensively used as a tool for enantio-discrimination when small molecules are aligned in chiral non-racemic lyotropic liquid crystalline phases, e.g. different types of helical polymers dissolved in organic solvents.5 On the other side, a third anisotropic NMR parameter, the residual chemical shift anisotropy, has been explored as a complementary tool to the application of RDCs to the structural analysis of small molecules.6 This special issue is focused on new NMR methodologies for the analysis of small organic molecules oriented in weak alignment media. This is an emerging field with plenty of room for new discoveries and development of necessary tools such as software and methodologies for data analysis, pulse sequences, and alignment media. However, its application is not yet widespread in the small molecules community. In this special issue, the readers will have the opportunity to enjoy a diverse set of research articles contributed by the experts in the field. I hope that the scientific community finds this special issue particularly inspiring to bring these new methodologies into their everyday work. I want to thank the Editor In Chief, Prof. James Keeler, for the invitation to edit this special issue. I also want to thank the members of the Editorial Board, Prof. Helmut H. Duddeck, Prof. Bozhana P. Mikhova, and Prof. Angela M. Gronenborn for their encouragement and support. Finally, my thanks to all my colleagues who gave me the honor of editing their contributions.

MRC Special Edition on Quantum-Chemical Computations of Magnetic Resonance Parameters

Methods for first-principles computation of NMR chemical shifts and EPR hyperfine coupling constants have long been part of the computational chemist's toolkit, with J-couplings and g-tensors as more recent additions. Considerable experience concerning the accuracy and performance of the various quantum-chemical models for these parameters has been accumulated by now, so that in many cases calculation of the key features of NMR or EPR spectra is becoming increasingly routine. This is especially true with the advent of efficient methods rooted in density functional theory and the unabated developments in computer hardware, which make ever larger, more “realistic” systems amenable to first-principles calculations. The fraction of papers reporting applications of such computations, either stand-alone or jointly with experimental results, is steadily increasing in all areas of chemistry. Because Magnetic Resonance in Chemistry is no exception to this development, the idea arose to dedicate a whole issue of the journal to this topic. As mentioned above, in many aspects the computation of magnetic resonance parameters is a mature field by now. A lot of challenges remain, however, such as the reliable modeling of environmental effects on the properties of interest. For example, how are the intrinsic NMR or EPR parameters of a molecule or an ion affected by embedding in a dynamic ensemble of polar solvent or an extended crystal matrix? Development of new methods and their validation for this purpose continues to be an active area of research. Another question often posed to theory is, why do the recorded magnetic resonance parameters adopt their particular values or follow the observed trends? The more sophisticated the underlying quantum-mechanical models get, the more difficult it often becomes to gain such insights that transcend the bare numbers. Again, special interpretative, computational tools need to be developed, tested and applied for this purpose. The present Special Issue is an attempt to provide a representative snapshot of the vibrant field of NMR and EPR computations and their applications, including some reviews of the latest developments pursued in some of the leading groups around the world. Special attention is called to periodic NMR calculations for infinite solids, an area where experiment and theory can team up in an especially fruitful way. There has been increasing interest in this field, particularly among the experimental community, and the use of calculation to support and interpret experimental results in the solid state is becoming increasingly common in many laboratories. We like to thank all the authors for their response to our call, the production team at Wiley for smooth processing of the manuscripts, as well as James Keeler, Martin McLean and Arwen Tapping for inviting us as guest editors and for their constant help along the way.

Quinuclidine complex with α‐cyclodextrin: a diffusion and 13C NMR relaxation study. Magnetic Resonance in Chemistry, 2008; 46:261–267

AbstractThe original article to which this Erratum refers was published in Magnetic Resonance in Chemistry, 2008; 46:261–267