Lymphangioma Research Articles

Recurrence of Omental Cystic Lymphangioma of the Greater Curvature in a 12-year-old Boy

Recurrence of Omental Cystic Lymphangioma of the Greater Curvature in a 12-year-old Boy

Cystic lymphangioma of the neck in adults: A report of four cases

Background: Cystic lymphangioma is a rare malformation characterized by a cystic structure deriving from detachment of lymph sacs from venous drainage systems. It is the result of the dilatation of capillary and sinusoidal lymphatic vessels still connected to the lymphatic network. Case presentation: In the following article, we describe the clinical and pathological features of cystic lymphangioma of the neck in four adults who underwent a surgical removal of the tumor with a well postoperative progress. Discussion and conclusion: Contrarily to children, the diagnosis of cystic lymphangioma in adults is exceptional. Patients with cystic lymphangioma of the neck are often asymptomatic; However, the lesion growth may cause respiratory disorders, dysphagia, or vascular and neurological compression syndromes. There are multiple modalities of treatment however the surgical complete removal remain the treatment of choice.

Maxillarys cystic lymphangioma A rare location

Lymphangiomas are benign hamartomas of the lymphatic vessels. They are congenital malformations that are usually present at birth or diagnosed within the first two years of age. Almost 75% of lymphangiomas occur in the head and neck region. Its occurrence in the maxillary antrum is one of the rarest locations. Very few cases have been reported in the literature. We report a case of maxillary sinus’ lymphangioma in a 73 year old female patient which presented for a 2 years evolving 3 cm right cheek swelling. Complete surgical excision was done without later recurrence.

Abdominal pain in a young man revealing an infected perigastric cystic lymphangioma.

Abdominal pain in a young man revealing an infected perigastric cystic lymphangioma.

A retroperitoneal cystic lymphangioma involving the spleen and pancreas: a case report.

In the present case, the girl complained of abdominal pain and dysuria. Clinical examinations showed a palpitated mass in her left pelvis; a radiology exam revealed a cystic mass infiltrating the spleen and pancreatic tail, reaching the pelvis. The mass, including the spleen and pancreatic tail, among the cystic compound was removed. The final diagnosis of benign CL was done based on a histopathology exam. A one-year follow-up showed no signs of recurrence. CL is usually asymptomatic. The retroperitoneal location of the mass delayed the diagnosis and allowed the mass to grow to a large size and compress nearby structures. The typical presentation of CL is usually a substantial, multichambers cystic mass. However, it could be easily misdiagnosed with other cystic tumors of the pancreas. Age-based differential diagnosis should be taken into consideration in children as abdominal mass can originate from gastrointestinal or genitourinary systems. The imaging features of CL are insufficient, and the final diagnosis depends on the histopathology exam. Furthermore, CL can mimic pancreatic cysts in its presentation and cite; therefore, it must be included in the diagnosing strategy whenever a retroperitoneal cyst is being investigated, as imaging features can be misleading. Surgical treatment of CL should be associated with long-term ultrasound follow-up to identify and manage recurrence early.

Unilateral breast enlargement in males during adolescence (10-19 years): Review of current literature and personal experience.

Idiopathic unilateral breast enlargement (UBE) in males is a, commonly overlooked, diagnosis of exclusion that requires careful history, meticulous physical examination, and pertinent laboratory studies to exclude the possible pathologic causes. The aims of the present update are to review the current literature on UBE in subjects during adolescent age (10-19 years) in 18 cases, and to report the personal experience in 13 adolescents referred to our unit during the last four decades. In total, our survey and personal experience include 31 UBE cases, 10 of whom (32.2 %) being idiopathic or familial gynecomastia (GM). In 3/31 (9.6%) UBE was due to breast sarcoma/ carcinoma; one patient (11-years old) had a 5-year history of painless lump in the right breast, which increased gradually in size followed by bloody nipple discharge. In the personal cases of 13 adolescents, a moderate to marked UBE was secondary to: treatment with androgens (2 β-thalassemic patients with hypogonadism), high estrogen/androgen ratio in 2 Klinefelter syndrome patients, peripheral aromatization of androgens in 1 patient with non-classical 21-hydroxylase deficiency (NC-21-OH-D). One patient had subareolar hematoma due to injury. In 2 patients (15,3%) marked UBE was due to cystic lymphangioma (histologically proved). Furthermore, 5 patients were characterized as idiopathic UBE In clinical practice, the persistence of UBE for long period before diagnosis necessitates attention and further evaluation. Underlying causes should be treated, when possible, while surgery can be offered to patients with persistent or atypical signs and/or symptoms of UBE. For the optimal management of this condition, better collaboration between primary care physician and specialists is mandatory.

Letter to the Editor: Abdominal Cystic Lymphangioma With Infection.

Surgical InfectionsAhead of Print Letter to the EditorLetter to the Editor: Abdominal Cystic Lymphangioma with InfectionYing Si, Ke Xiao, and Yongmao HuangYing SiAddress correspondence to: Dr. Ying Si, Department of Infectious Diseases, Department of Tuberculosis, Infection, and Immunity Laboratory, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou, Sichuan 646000, China E-mail Address: 445137508@qq.comDepartment of Infectious Diseases, Department of Tuberculosis, Infection, and Immunity Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.Search for more papers by this author, Ke XiaoDepartment of Infectious Diseases, Department of Tuberculosis, Infection, and Immunity Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.Search for more papers by this author, and Yongmao HuangDepartment of Infectious Diseases, Department of Tuberculosis, Infection, and Immunity Laboratory, The Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China.Search for more papers by this authorPublished Online:11 Apr 2023https://doi.org/10.1089/sur.2022.323AboutSectionsView articleView Full TextPDF/EPUB Permissions & CitationsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail View article"Letter to the Editor: Abdominal Cystic Lymphangioma with Infection." Surgical Infections, , pp. –FiguresReferencesRelatedDetails Volume 0Issue 0 InformationCopyright 2023, Mary Ann Liebert, Inc., publishersTo cite this article:Ying Si, Ke Xiao, and Yongmao Huang.Letter to the Editor: Abdominal Cystic Lymphangioma with Infection.Surgical Infections.ahead of printhttp://doi.org/10.1089/sur.2022.323Online Ahead of Print:April 11, 2023PDF download

Adult Abdominal Cystic Lymphangioma Revealed by Intra Peritoneal Hemorrhage: A Case Report

Adult Abdominal Cystic Lymphangioma Revealed by Intra Peritoneal Hemorrhage: A Case Report

Small Bowel Cystic Lymphangioma: An Uncommon Finding During Single-Balloon Enteroscopy

CASE REPORT Cystic lymphangiomas are rare, congenital, nonmalignant lesions, extremely rare in the gastrointestinal tract.1 We report the case of a 76-year-old man referred to our unit for abdominal pain and anemia. Colonoscopy showed hepatic flexure adenocarcinoma confirmed by a contrast-enhanced computed tomography scan, which also revealed a hypodense and intraluminal mass located in the distal jejunum. Therefore, single-balloon-assisted enteroscopy with an antegrade approach was performed. In the distal jejunum, a yellow, glossy, and polylobate polypoid lesion of 30 mm in diameter was found. The lesion showed a tender, smooth, and squeezable surface: Bite-on-bite biopsies were performed, and a large amount of chylous/purulent fluid leaked from the lesion, which gradually deflated (Video 1). Histopathological report was consistent with cystic lymphangioma. Afterward, the patient underwent right hemicolectomy and jejunal resection. Cystic lymphangiomas result from the failure of lymphatic channels to communicate with the main lymphatic system.1 Cysts may contain serous, chylous, bloody, or purulent fluid. Intra-abdominal lymphangiomas mostly occur in the mesentery, followed by the omentum, mesocolon, and retroperitoneum.2 Involvement of solid or cave organs is extremely rare.3 Lymphangiomas are generally asymptomatic or responsible for nonspecific symptoms, including abdominal pain, diarrhea, and bleeding; volvulus typically occurs in mesenteric small bowel lymphangiomas, requiring urgent surgery.2 Enteroscopy, colonoscopy, and endoscopic ultrasonography are useful tools for the diagnosis and management of abdominal lymphangiomas. For symptomatic cystic lesions or tumors larger than 20 mm, surgical resection is the treatment of choice.4 In selected patients, endoscopic resection is a feasible option.4 Lymphangiomas comprise 3% of benign small bowel tumors5; however, it is expected that the frequency of their detection will increase in the coming years given the augmented diffusion of both video capsule and enteroscopy. Therefore, it is important for small bowel endoscopists to be able to recognize these lesions to offer the best therapeutic options to their patients. {"href":"Single Video Player","role":"media-player-id","content-type":"play-in-place","position":"float","orientation":"portrait","label":"Video 1","caption":"Jejunal cystic lympangioma finding during single-balloon enteroscopy.","object-id":[{"pub-id-type":"doi","id":""},{"pub-id-type":"other","content-type":"media-stream-id","id":"1_4vtc2xhf"},{"pub-id-type":"other","content-type":"media-source","id":"Kaltura"}]} DISCLOSURES Author contributions: S. Cocca, G. Pontillo and G. Grande involved in drafting of the manuscript. G. Grande and G. Pontillo performed enteroscopy. S. Cocca, H. Bertani, S. Russo, A. Mussetto and R. Conigliaro performed critical revision of the manuscript. S. Cocca is the article guarantor. Financial disclosure: None to report. Informed consent was obtained for this case report.

Abdominal lymphangioma in a child: A case report

Abstract Cystic lymphangioma of the mesentery and retroperitoneum is a rare, slow-growing lesion. It produces a variety of symptoms, from an asymptomatic abdominal mass to an acute abdomen. In cases when it is possible, complete surgical excision is the optimum method of treatment. We describe a 5-year-old boy who had a brief history of abdominal pain and distension. Imaging analysis revealed an intraabdominal multiloculated cyst lesion that was likely an omental or hydatid cyst. The patient underwent surgery, and the cyst could be completely excised without any gut resection. The tumor biopsy revealed a cystic lymphangioma.

A Rare Combination of Acquired Lymphangioma of the External Auditory Canal and Cholesteatoma in the Middle Ear Cavity.

Lymphangioma (LM) is a rare but benign tumor derived from lymphatic malformation, which is extremely rare in the auditory canal or middle ear cavity. We presented a case of acquired lymphangioma of the external auditory canal combined with cholesteatoma in the middle ear cavity. To our best knowledge, this is the first case of combined lesions of lymphangioma and cholesteatoma in English literature.

Intestinal cystic lymphangioma: A diagnostic challenge in adults

Intestinal cystic lymphangioma: A diagnostic challenge in adults

Cyst Lynphangioma of the bilateral kidney: Case report and a literature review

Cystic lymphangioma is a rare malformative benign tumor of the lymphatic vessels with various localizations. The retroperitoneal localization is less frequent compared to the mesenteric one. Its clinical presentation is polymorphic. The diagnosis is evoked by imaging but requires histological confirmation. The treatment of choice is surgical. Cystic lymphangioma of retroperitoneal location is a rare condition. The therapeutic management is based on complete removal of symptomatic lesions or complications to limit the risk of recurrence. Recurrence may be deferred in asymptomatic patients.

Needle-based confocal laser endomicroscopy for cystic lymphangiomas of the pancreas: the first case series.

Cystic lymphangiomas of the pancreas (CLP) were first described by Koch in 1913 [1]. The origin of these benign lesions is not well defined; they could either be congenital malformations or secondary to a lymphatic vessel obstruction due to either radiotherapy, surgery, infection, or trauma [2]. The main challenge in pancreatic cystic lesions (PCLs) is the diagnostic certainty [3]. Needle-based confocal laser endomicroscopy (nCLE), described in pancreatic diseases in 2011 [4], is a very specific technique for the diagnosis of the main PCL [5]. The first description of the identifiable structures by nCLE in CLP is proposed below.

Abdominal Distension Revealing Retro-Peritoneal Cystic Lymphangioma

Cystic lymphangiomas are benign tumors of the lymphatic vessels. It is characterized by its clinical polymorphism. Its retroperitoneal localization is rare. Its diagnosis relies mainly on imaging but needs histological confirmation. Its treatment is surgical. It can have an adverse evolution, especially when its volume causes compressive complications. We report the case of a 65-year-old male patient who presented abdominal distension and pain, whose abdominal scan showed a voluminous retroperitoneal mass. The interest of our case resides in the impressive volume of the tumor, its expressive scanographic semiology and its favorable evolution.

Giant Pancreatic Lymphangioma Herniating Above the Diaphragm.

Lymphangiomas of pancreatic origin are rare and can often be found with abdominal symptoms or incidentally on imaging. A 46-years-old female presented with epigastric abdominal pain and vomiting, and twenty-pound weight loss over 3months. Computed tomography of the abdomen showed a septated mass of the distal pancreas measuring 25.4cm in largest diameter and extending superiorly into the mediastinum via a hiatal hernia. Endoscopic ultrasound demonstrated abutment but no invasion of the esophagus and stomach. She underwent an exploratory laparotomy with retroperitoneal mass excision, distal pancreatectomy, splenectomy, and hiatal hernia repair with Dor fundoplication. Pathology was consistent with a cystic lymphangioma. Patient was discharged on postoperative day 3 and remained recurrence free for over a year.

Giant Pediatric Lymphangioma Resected by Robotic Surgery in the Mediastinum – Case Report

Lymphangiomas are slow-developing benign malformations of the lymphatic system. They are characterized by lymphatic proliferation in mucous membranes. The diagnosis is based on clinical history and, mainly, imaging findings, such as CT and NMR. Standard treatment demands total surgical excision for curative purposes A 1 year and 4 months old boy went to the hospital’s ER presenting with cough and fever. Chest X-rays showed enlarged mediastinum, and computed tomography (CT) revealed a large cystic lesion in the anterior mediastinum measuring 91x40x68 mm. Propaedeutic was extended with nuclear magnetic resonance (NMR) and transthoracic echocardiogram. A multidisciplinary team formed by pediatricians, pediatric oncologists and thoracic surgeons decided for surgical resection of the mass with the thoracic robotic surgery. Although sternotomy and thoracotomy are classic surgical choices, resection by robotic surgery was preferred in this case. Port placement: the optical portal was positioned at the level of the ninth intercostal space in the posterior axillary line, and the others were positioned under vision, respecting a minimum distance of 7 cm between them. In this case, the trochanters positioning outside of the “remote center” was important, because of the small pleural cavity with less room for tweezers mobility. The dissection and release of tumor adhesions to the brachiocephalic vein, superior vena cava and internal thoracic veins were carried out and the tumor was removed. The patient’s condition improved in the postoperative period, being discharged from the ICU in the first postoperative day and hospital discharge was on the third postoperative day, without any complications. The anatomopathological confirmed mediastinal cavernous lymphangioma.

Retroperitoneal cystic Lymphangioma in adulthood – A case report

Retroperitoneal cystic Lymphangioma in adulthood – A case report

A rare occurrence of an incidental primary intra-abdominal Cystic Lymphangioma in a Middle Eastern adult female: A case report.

The authors hereby demonstrate the case of a 46-year-old lady who presented to the outpatient general surgery clinic at our university hospital complaining of chronic right hypochondriac abdominal pain. Investigative radiological imaging marked a cystic formation with well-defined borders and homogenous content extending from the lower pole of the right kidney to the lower hepatic border. Surgical intervention was performed by completely resecting the lesion in question. Directly afterward, histopathological analysis was achieved and established the diagnosis of a CL.Conclusion:CL is a rare neoplasm with ill-defined symptoms and ambiguous clinical presentations. They remain poorly studied due to their rarity and lack of sufficient data in the published literature. This magnifies the importance of clinical awareness and time-efficient surgical intervention. Documenting these cases aids in identifying their subsequent etiological origins, disease-specific risk factors, clinical course, and yields proposals of novel therapeutic approaches.

Cystic pancreatic lymphangioma: a case report

BackgroundLymphangiomas are benign vascular tumors arising from the lymphatic system. They commonly affect the head and neck regions. Pancreatic involvement is extremely rare. Even though they are rare, it should be considered as a differential diagnosis for patients who present with pancreatic mass.Case presentationWe report the case of a 6-year-old African male patient who presented with abdominal mass and dull aching pain of 6 months duration. He was examined and underwent excision, with biopsy showing pancreatic lymphangioma.ConclusionThese tumors are benign and slow growing and have potential to regress spontaneously. Thus, most literature agrees that surgical interventions should be reserved for symptomatic cases.