Luminescence Properties Research Articles

Peptide Based Quantum Dots Conjugates as Promising Theranostic Candidates in Nanomedicines: Applications in Drug Delivery and Bioimaging

AbstractAdvancement in nanotechnology paves new way in nanomedicine via synthesis of various scaffolds bearing multifunctionalities having characteristics of both as diagnostic and therapeutic applications. Quantum dots (QDs) with exceptional luminescent properties exhibited some unbeatable characteristics of small size with ease in surface modifications and thus make them suitable candidates to be used in drug delivery and diagnosis of diseases. Meanwhile, various type of peptides are known in literature for their excellent therapeutic properties and thus make them promising candidates to be used as conjugate partner with the QDs. Highly luminescent properties and surface modifications flexibility of QDs, further urge to use them as promising conjugate partner with many small molecules including peptides and thus found applications in the field of nanomedicines. Thus Peptides ‐QDs conjugates exhibited the properties of both QDs and bioactivity, biocompatibility features of peptides and hence leave behind the limitation of both the individual partners (i. e. QDs and peptides). Thus the combined Peptides‐QDs conjugates acts as theranostic agent for various diseases where these acts as both imaging and drug delivery agent. Hence the present review focused on the theranostic applications of the Peptides‐QDs conjugates in various area of the nanomedicines. Also we focus on the area of improvement and advancement in nanomedicines for the diagnosis and treatment of the diseases in the early stages.

Warm red light emitting Eu(III) complexes synthesis and analysis including computational methods for photonic applications

Six luminescent europium organic complexes have been synthesized and studied for their luminescent properties. The synthesized complexes were analyzed through elemental analysis, XRD, SEM, EDAX, FT-IR, NMR and thermogravimetry. The complexes exhibit crystalline behavior and possess decent thermal stability. Photoluminescence study on complexes were conducted in both solid and solution states, the results indicate the characteristic red emission. With the addition of ancillary ligands, water molecules are replaced from inner coordination sphere, leading to enhanced luminescence properties. The colorimetric parameters (CIE, CP%, CCT, u′, v′) suggest aptness of these complexes in red light illuminating OLEDs. The J-O parameters were calculated experimentally and theoretically with the help of LUMPAC software. Theoretical and experimental results agree well reflecting the efficacy of the outcomes. As a result of red emission, these complexes could have interesting photonics applications. The biological studies indicate the probable use of these complexes in the medical industry.

Two 3D Co(II)-based hydrogen-bonded networks as luminescent sensors for detection of Al3+, Pb2+ and vitamin B2

Rational design of coordination polymers (CPs) as luminescent sensors, has attracted great interest in recent years. In this work, two new Co(II) CPs with formula as {[Co(5-AIP)(1,2-Mbix)]·2H2O}n (1) and {[Co(5-AIP)(1,3-Mbix)]}n (2) have been synthesized and characterized (5-AIP = 5-aminoisophthalic acid, 1,2-Mbix = 1,2-bis(2-methylimidazole-1-methyl)benzene, 1,3-Mbix = 1,3-bis(2-methylimidazole-1-methyl)benzene). CP1 features a 3D hydrogen-bonded network with 5-connected (46·64) bnn topology. CP2 shows a 3D hydrogen-bonded network as a trinodal (3,4,8)-connected topopogy with the symbol of (3·5·7)2(32·6·72·8)(32·54·616·84·102). Two CPs both show excellent luminescent property with good stability in water. Both CPs can effectively detect Al3+, Pb2+ and vitamin B2 (VB2) in water with limits of detection being 84 nM, 0.10 and 0.17 μM for CP1, 25 nM, 0.09 and 0.29 μM for CP2, respectively. Furthermore, two CPs also can detect Al3+ and Pb2+ in real lake water and VB2 in serum. The sensing mechanism was investigated by various detection means. The test films of CP1 and CP2 were also prepared for the visual detection of Al3+, Pb2+ and VB2 in water. This work presents two effective Co(II) CPs as the functional platform for sensing Al3+, Pb2+ and VB2 in aqueous solution.

Revelation of room temperature liquid crystallinity and yellow-orange electroluminescence (EQE>7%) in a columnar self-assembled N-annulated perylene bisimide

The synthesis of highly fluorescent compounds is a critical necessity to facilitate cost-effective and metal-independent production of organic light-emitting diodes (OLEDs). This investigation introduces a readily soluble, electron-deficient N-annulated perylene bisimide (PBI-NST) equipped with a swallow tail, exhibiting room temperature columnar oblique mesophase with a low clearing point and high photoluminescence quantum yield, positioning it as a promising candidate for efficient OLEDs. Leveraging the luminescent properties of PBI-NST, a series of OLED devices were fabricated with PBI-NST as the sole emitter and at various concentrations in CBP host material. Impressively, doped devices employing the compound at 0.5 wt% emitter within the host material CBP displayed an exceptional external quantum efficiency (EQE) of 7.2 %, accompanied by a luminance of 2689 cd/m2. Further, a voltage dependent emission tuning was also noticed. The notable increase in EQE is mainly attributed to the contributions of hybrid local and charge transfer (HLCT) and triplet–triplet annihilation (TTA) process. The substantial enhancement in EQE marks a significant advancement in the application of multifunctional columnar self-assembled materials for OLED development.

Fluorescent Mn3O4 quantum dot as catechol oxidase nanozyme: A robust nano-platform for sensitive dopamine detection

The development of multifunctional semi-conductor nano-enzymes has attained significant interest recently, due to their ease in fabrication, cost-effectiveness, and wide range of applications. In this work, we report the synthesis of ammine-functionalized Mn3O4 quantum dots (Mn3O4 QDs) with excellent luminescence properties. These QDs have been developed via the reduction of permanganate using L-cysteine through a simple, facile one-step bottom-up approach. The steady-state enzyme kinetic studies revealed the superior Catechol-Oxidase mimic activity of the Mn3O4 QDs with a Michaelis-Menten constant (Km) of 133.19 µM, and maximum reaction velocity (Vmax) of 69.40 µMs−1. Due to this superior enzymatic activity, dopamine (DA) gets easily oxidized into DA-quinone and eventually polymerized to form polydopamine. Schiff base/Michael addition reaction between nucleophilic ammine on the surface of QDs and the aromatic chain makes the probe and analyte come closer and leads to the formation of a charge transfer complex, resulting in fluorescence quenching of QDs. This fluorescence quenching has been quantified to develop a turn-off sensor for DA. The sensing characteristics are highly selective and sensitive towards DA with a detection limit of 18 nM. The synthesised Mn3O4 QDs with superior enzyme-mimicking properties have tremendous potential as fluorescent probes in imaging and health care applications.

Study of Thermoluminescence and Optically Stimulated Luminescence Properties of Synthesised CaB2O4 Nanoparticles Doped with Copper.

CaB2O4 nanorods doped with different concentrations of Cu were prepared by using co-precipitation method. The recorded Thermoluminescence (TL) and Optically stimulated luminescence (OSL) of CaB2O4:Cu samples for different concentrations of Cu irradiated with 6Gy of X-Ray shows that 0.05 at.wt% of Cu concentrations have higher sensitivity. The TL and OSL kinetic parameters of glow curves were evaluated using "tgcd" and conventional fitting methods. The TL glow curve of the CaB2O4:Cu have three individual glow peaks with maximum peak temperatures at 404.50, 453.04 and 484.02K respectively. The OSL glow curves of the CaB2O4:Cu nanoparticles follow non-first order kinetics which can be fitted with the sum of two first order decay curves.

Magneto-Luminescent Two-Dimensional Nanosheets of Gadolinium and Gold Nanocluster Assemblies with Surface Molecular Functionalization for White Light Emission.

We report the formation of photoluminescent two-dimensional (2D) crystalline nanosheet assemblies of gadolinium ions and ligand-stabilized gold nanoclusters (Gd-Au NCs). Transmission electron microscopy, selected area electron diffraction in conjunction with atomic force microscopy, and field-emission scanning electron microscopy analyses substantiated the 2D nature of Gd-Au NC nanosheets. The optical and magnetic properties of the nanosheets were investigated by photoluminescence measurements and vibrating-sample magnetometry analyses. The so-formed crystalline product was further utilized to generate a synchronous tricolor (orange, green, and blue) emission from a single excitation wavelength through an inorganic surface complexation reaction. The independent emissions were tunable after ligand functionalization by acetylsalicylic acid and fluorescein on the Gd-Au NC assembly. Interestingly, the assembled superstructure with augmented quantum yield led to white light emission at λexc ≈ 325 nm with CIE of (0.34, 0.33) and CRI value of >85 in the liquid phase. Furthermore, the ability to modulate the luminescence properties through the surface complexation of the 2D nanosheets of Au NCs may bring about new avenues toward applications in light-emitting devices, sensing, and biomedical imaging.

Unconventional Luminescence Polymer with Color-Tunability based on Solvent-induced Electrostatic Potential Distribution of Fluorophore.

Tuning the full-color emission of polymers holds significant promise. However, preparing unconventional luminescencepolymers with color-tunability in dilute solution and understanding the relationship between non-covalent interactions and luminescent behavior remains a great challenge. We report two emitters (P1 and P2) incorporating tetracoordinate boron. The P1 with non-conjugated D-π-A structure, exhibited red delayed fluorescence at 645 nm with quantum yield of 9.15% in aggregates. Notably, the emission wavelength of P1 can be tuned from 418 to 588 nm at different solvent. Similarly, the emission wavelength of P2 can also be adjusted by manipulating the interactions between the solvent and fluorophore. Experimental characterization and theoretical calculations indicate that the B←N bond and electronic interactions betweensolvent and fluorophore significantly regulate the equilibrium the electrostatic potential (ESP) and the intramolecular O···O interactions of P1, thereby modulating its emission wavelength. Additionally, these polymers showed excellent potential in fluoride ions detection. This work provides new insights into the complex effects of intermolecular interactions on luminescent properties.

Vacancy Effect on the Luminescent and Water Responsive Properties of Vacancy-ordered Double Perovskite Derivatives.

Vacancy-ordered perovskites and derivatives represent an important subclass of hybrid metal halides with promise in applications including light emitting devices and photovoltaics. Understanding the vacancy-property relationship is crucial for designing related task-specific materials, yet research in this field remains sporadic. For the first time, we use the Connolly surface to quantitatively calculate the volume of vacancy (V□, □ = vacancy) in vacancy-ordered double perovskite derivatives (VDPDs). A relationship between void fraction and the structure, photoluminescent properties and humidity stability was established based on zero-dimensional (0-D) [N(alkyl)4]2Sb□Cl5□'-type VDPDs. Compared with the more commonly studied A2M(IV)X6□-type double perovskite (A = cation, M = metal ion, X = halide), [N(alkyl)4]2Sb□Cl5□' features double vacancy sites. Our results demonstrate an inverse relationship between the photoluminescent quantum yield and V□ in 0-D VDPDs. Additionally, structural transformation from A2SbCl5 to A3Sb2Cl9 was first reported, during which the novel 'gate-opening' gas adsorption phenomenon was observed in VDPDs for the first time, as evidenced by 'S'-shaped sorption isotherms for water vapor, indicating a cation-controlled water-vapor response behavior. A mixed-cation strategy was developed to modulate the humidity stability of VDPDs. Characterized by controllable water-responsive behavior and unique 'on-off-on' luminescent switching, A2M(III)□X5□'-type materials show great promise for multi-level information anti-counterfeiting applications.

Vacancy Effect on the Luminescent and Water Responsive Properties of Vacancy‐ordered Double Perovskite Derivatives

Vacancy Effect on the Luminescent and Water Responsive Properties of Vacancy‐ordered Double Perovskite Derivatives

Synthesis and luminescence properties of carbon quantum dots with core@shell structures

The luminescence stability of carbon quantum dots (CQDs) in air impedes their extensive applications. Ample –NH2 groups on the surface of a green carbon quantum dots (GCQDs) had high organic reactivity, the surface of GCQDs was modified with allyl functional groups through a simple surface substitution reaction (named as GCQD-A). The surface of the GCQD-A was continuously formed a thin organic shell by free radical copolymerization reaction with methyl methacrylate and styrene respectively, and they were named as GCQD@PMMA and GCQD@PS respectively. The allyl functional groups on the surface of GCQD-A, the shell composition of GCQD@PMMA and GCQD@PS were characterized by their 1H nuclear magnetic resonance (1H NMR) data and infrared adsorption spectra. The luminescence stabilities for GCQD@PMMA and GCQD@PS in air were greatly improved compared with that for the GCQDs. The work can provide a novel method to get stable luminescence of CQDs in air, and it will extend their application areas in solid state.

Reversible Local Protonation-Deprotonation: Tuning Stimuli-Responsive Circularly Polarized Luminescence in Chiral Hybrid Zinc Halides for Anti-Counterfeiting and Encryption.

Precise control over the organic composition is crucial for tailoring the distinctive structures and properties of hybrid metal halides. However, this approach is seldom utilized to develop materials that exhibit stimuli-responsive circularly polarized luminescence (CPL). Herein, we present the synthesis and characterization of enantiomeric hybrid zinc bromides: biprotonated ((R/S)-C12H16N2)ZnBr4 ((R/S-LH2)ZnBr4) and monoprotonated ((R/S)-C12H15N2)2ZnBr4 ((R/S-LH1)2ZnBr4), derived from the chiral organic amine (R/S)-2,3,4,9-Tetrahydro-1H-carbazol-3-amine ((R/S)-C12H14N2). These compounds showcase luminescent properties; the zero-dimensional biprotonated form emits green light at 505 nm, while the monoprotonated form, with a pseudo-layered structure, displays red luminescence at 599 and 649 nm. Remarkably, the reversible local protonation-deprotonation behavior of the organic cations allows for exposure to polar solvents and heating to induce reversible structural and luminescent transformations between the two forms. Theoretical calculations reveal that the lower energy barrier associated with the deprotonation process within the pyrrole ring is responsible for the local protonation-deprotonation behavior observed. These enantiomorphic hybrid zinc bromides also exhibit switchable circular dichroism (CD) and CPL properties. Furthermore, their chloride counterparts were successfully obtained by adjusting the halogen ions. Importantly, the unique stimuli-responsive CPL characteristics position these hybrid zinc halides as promising candidates for applications information storage, anti-counterfeiting, and information encryption.

Recent progress in lanthanide-based fluorescent nanomaterials for tetracycline detection and removal.

Tetracycline (TC) has been widely used in clinical medicine and animal growth promotion due to its broad-spectrum antibacterial properties and affordable prices. Unfortunately, the high toxicity and difficult degradation rate of TC molecules make them easy to accumulate in the environment, which breaks the ecological balance and seriously threatens human health. Rapid and accurate detection of TC residue levels is important for ensuring water quality and food safety. Recently, fluorescence detection technology of TC residues has developed rapidly. Lanthanide nanomaterials, based on the high luminescence properties of lanthanide ions and the high matching with TC energy levels, are favored in the real-time trace detection of TC due to their advantages of high sensitivity, rapidity, and high selectivity. Therefore, they are considered potential substitutes for traditional detection methods. This review summarizes the synthesis strategy, TC response mechanism, removal mechanism, and applications in intelligent sensing. Finally, the development of lanthanide nanomaterials for TC fluorescence detection and removal is reasonably summarized and prospected. This review provides a reference for the establishment of a method for the accurate determination of TC content in complex food matrices.

Micronano Lasers Based on Aggregation-Induced Emission Molecules: Diverse Resonant Cavities Investigation.

Aggregation-induced emission (AIE) molecules have great potential to enhance the performance of micronano lasers due to their excellent aggregated luminescence properties, so it is valuable to expand their applications in micronano lasers. In this work, a typical AIE active fluorescent dye motif 9,10-bis(2,2-diphenylvinyl) anthracene (BDPVA) was selected as the gain medium. First, drop-casting was used to fabricate BDPVA single-crystal nanowires, which can be used as Fabry-Perot (FP)-type resonators with a lasing threshold of 49.4 μJ/cm2. Furthermore, we innovatively doped BDPVA molecules as gain mediums into external polymer Whispering-Gallery-Mode (WGM)-type resonators via the emulsion self-assembly method. Fabricated BDPVA-doped polystyrene (PS) microspheres exhibit a much lower lasing threshold of 9.04 μJ/cm2. These results prove that the BDPVA molecules, in addition to realizing the reported AIE single-crystal lasers, can also be used as a guest-doped gain medium in the resonant cavity for obtaining better fluorescence gain. In addition, multimode tunability of two types of lasers has been successfully achieved by tuning the structure of the resonant cavity. This work further expands the application potential of AIE materials and will provide a useful reference for the rational design and fabrication of photonic micronano laser components using AIE materials.

Reversible Local Protonation‐Deprotonation: Tuning Stimuli‐Responsive Circularly Polarized Luminescence in Chiral Hybrid Zinc Halides for Anti‐Counterfeiting and Encryption

Precise control over the organic composition is crucial for tailoring the distinctive structures and properties of hybrid metal halides. However, this approach is seldom utilized to develop materials that exhibit stimuli‐responsive circularly polarized luminescence (CPL). Herein, we present the synthesis and characterization of enantiomeric hybrid zinc bromides: biprotonated ((R/S)‐C12H16N2)ZnBr4 ((R/S‐LH2)ZnBr4) and monoprotonated ((R/S)‐C12H15N2)2ZnBr4 ((R/S‐LH1)2ZnBr4), derived from the chiral organic amine (R/S)‐2,3,4,9‐Tetrahydro‐1H‐carbazol‐3‐amine ((R/S)‐C12H14N2). These compounds showcase luminescent properties; the zero‐dimensional biprotonated form emits green light at 505 nm, while the monoprotonated form, with a pseudo‐layered structure, displays red luminescence at 599 and 649 nm. Remarkably, the reversible local protonation‐deprotonation behavior of the organic cations allows for exposure to polar solvents and heating to induce reversible structural and luminescent transformations between the two forms. Theoretical calculations reveal that the lower energy barrier associated with the deprotonation process within the pyrrole ring is responsible for the local protonation‐deprotonation behavior observed. These enantiomorphic hybrid zinc bromides also exhibit switchable circular dichroism (CD) and CPL properties. Furthermore, their chloride counterparts were successfully obtained by adjusting the halogen ions. Importantly, the unique stimuli‐responsive CPL characteristics position these hybrid zinc halides as promising candidates for applications information storage, anti‐counterfeiting, and information encryption.

Theoretical study on the luminescence mechanism of AIEgens based HOFs adsorbing small molecules

The diversity and reversibility of non-covalent interactions give hydrogen-bonded organic frameworks (HOFs) excellent gas adsorption and separation performance. Here we designed and synthesized HOFs based on aggregation-induced emission luminogens (AIEgens) to visualize the adsorption process of HOFs. We focused on the SQ system and its solvated SQ frameworks by different solvent conditions, employing the thermal vibration correlation function rate formalism coupled hybrid quantum mechanics/molecular mechanics protocol, to elucidate the relation between crystal structure and luminescent properties, as well as the specific adsorption ability of porous SQ HOF crystals on acetylene gas. It is found that compare to SQ crystal, the SQ symmetry in cocrystals are improved, and SQ-DCM cocrystal has the best symmetry. The absorption spectra of five SQ-based crystals are close to each other, and their emission spectra blueshifted from 540 nm of SQ, to 509 nm, 508 nm, 507 nm of SQ-EA, SQ-ACN, SQ-DCM, and then to 495 nm of SQ-TOL, consistent with experimental results. The kic of solvated cocrystals are about 1∼2 orders of magnitude smaller than that of non-solvated crystal SQ, resulting in significantly higher Φexp of solvated cocrystals than that of un-solvated one. DCM with small volume and C2v point group is more suitable for SQ crystal channel, indicating that small free region and shape matching are the key factors affecting the reversibility of crystallization of porous frames during solvent transport. Finally, the volume of the adsorbed gas C2H2 which is close to DCM, is more easily adsorbed by SQ framework. Our study offers theoretical insights into the design of porous crystals for gas adsorption and separation applications.

Synthesis, crystal Structure, theoretical calculation and luminescence properties of Cu(Ⅱ), Co(Ⅱ), Ni(Ⅱ) and Zn(Ⅱ) quinolinyl benzimidazole complexes with multiple coordination number induced by proton

The innovative ligand H2L, featuring a benzimidazole structure substituted with 8-hydroxyquinoline and equipped with N,O donor sites, underwent successful synthesis and meticulous characterization. Notably, this ligand was exclusively synthesized through catalysis under protonated conditions, accompanied by an in-depth exploration of the catalytic mechanism. Employing single-crystal X-ray diffraction, we acquired and authenticated four distinct asymmetric double-decker sandwich mononuclear transition metal complexes: [Cu(HL)2]·2H2O, [Co(HL)2]·CH3OH, [Ni(HL)2] and [Zn(HL)2]·CH2Cl2. Among these, complex 1 revealed an intriguing five-coordinate Cu(II) center adopting a distorted square pyramidal geometry, whereas the central metal ions in complexes 2–4 exhibited a six-coordinate configuration, characterized by a distorted octahedral geometry. Noteworthy is the observation that the dihedral angles within the crystal structures of complexes 2–4 approached approximately 90° to a significant extent. To delve deeper into the electronic properties and transitions, meticulous DFT and TD-DFT calculations were performed on both the ligand H2L and complexes 1–4. Furthermore, a comprehensive investigation into the luminescence properties of both H2L and its complexes was conducted, revealing a pronounced luminescence quenching effect in the complexes compared to the ligand. Through thorough analysis utilizing Hirshfeld surface examination and IRI analysis, various weak intermolecular interactions within the system were elucidated.

(Invited) Ultrathin Gap Nanoantenna: Crystal Phase Transitions and Luminescent Properties

We report Te-doped GaP nanowires (NWs) with positive tapering and radii measuring as low as 5 nm grown by the self-assisted vapor-liquid-solid mechanism using selective-area molecular beam epitaxy. The occurrence of the ultrathin nanoantenna showed a dependence on pattern pitch (separation between NWs) with a predominance at 600 nm pitch, and exhibited radius oscillations that correlate with polytypic zincblende/wurtzite segments. A growth model explains the positive tapering of the NW leading to an ultrathin tip from the suppression of surface diffusion of Ga adatoms on the NW sidewalls by Te dopant flux. The model also provides a relationship between the radius modulations and the oscillations of the droplet contact angle, predicting the quasi-periodic radius oscillations and corresponding crystal phase transitions. The GaP NWs showed strong low temperature micro-photoluminescence exciton-related emission, indicating a bandgap difference between the zincblende/wurtzite segments, with phonon replicas due to the transverse optical phonon mode. These results establish a link between dopants and the ability to control NW morphology, crystal phase and luminescent properties with possible applications in thermoelectrics, quantum emitters and photodetectors.

Chiral Perovskite Heterostructure Films of CsPbBr3 Quantum Dots and 2D Chiral Perovskite with Circularly Polarized Luminescence Performance and Energy Transfer.

This work reports the synthesis of chiral perovskite heterostructure films by combining a two-dimensional (2D) chiral (R-/S-MBA)2PbI4 perovskite with CsPbBr3 quantum dots (QDs). The as-synthesized chiral heterostructure films exhibit obvious circularly polarized luminescence (CPL) properties, even though pure 2D chiral perovskite cannot present photoluminescence. It indicates that the chirality of the excited state of the QDs originates from the 2D chiral perovskite. The circular polarization-resolved transient absorption (TA) spectra further demonstrate that the CPL response of heterostructure films originates from the energy transfer between the chiral perovskite layer and QDs layer and the suppression of spin relaxation, which induces the imbalance of the spin population of excited states in QDs layer. In addition, the photoluminescence (PL), circular dichroism (CD), and CPL spectra of these heterostructure films can be controlled by varying the thickness and component of the chiral perovskite layer, which demonstrates that the anion exchange between chiral perovskite and CsPbBr3 QDs can tune the chemical composition and optoelectronic properties due to the low bonding energy difference between them and decrease the strain within the QDs layer to reduce the radiative recombination lifetime. This work provides guidance for the synthesis of chiral perovskites with a strong CPL response and further provides insight into the origination of CPL.

(Invited) Manipulation of Locally-Excited, Charge-Transfer, and Charge-Separated States at Organic-Inorganic Heterointerfaces

Precise engineering of excited-state interactions between an organic conjugated molecule and a two-dimensional semiconducting inorganic nanosheet, specifically the manipulation of locally-excited (LE), charge-transfer (CT), and charge-separated (CS) states, still remains a challenge for state-of-the-art photochemistry. In this study we successfully observed a long-lived, highly emissive CT state at structurally well-defined hetero-nanostructure interfaces of photoactive pyrene and two-dimensional (2D) MoS2 nanosheet via N-benzyl succinimide bridge (Py-Bn-MoS2). Spectroscopic measurements revealed that the LE state of pyrene in Py-Bn-MoS2 efficiently generates an unusual emissive CT state without further yielding the CS state. Theoretical studies supported the interaction of MoS2 vacant orbitals with the pyrene excited state to form a CT state. This is the first example of realizing a mixing luminescence property of organic–inorganic 2D hetero-nanostructures by an accurate design of bridge structure, and therefore represents an important step in their applications for energy conversion and optoelectronic devices and sensors.[1] J. Baek, T. Umeyama, W. Choi, Y. Tsutsui, H. Yamada, S. Seki, H. Imahori, Chem. Eur. J., 24, 1561 (2018).[2] T. Umeyama, T. Ohara, Y. Tsutsui, S. Nakano, S. Seki, H. Imahori, Chem. Eur. J., 26, 6726 (2020).[3] T. Umeyama, H. Xu, T. Ohara, Y. Tsutsui, S. Seki, and H. Imahori, J. Phys. Chem. C, 125, 13954 (2021).[4] T. Umeyama, D. Mizutani, Y. Ikeda, W. R. Osterloh, F. Yamamoto, K. Kato, A. Yamakata, M. Higashi, T. Urakami, H. Sato, H. Imahori, Chem. Sci., 14, 11914 (2023).