Lumbar Intervertebral Disc Protrusion Research Articles

Retracted: Clinical Effect of the Treatment of Lumbar Intervertebral Disc Protrusion

Retracted: Clinical Effect of the Treatment of Lumbar Intervertebral Disc Protrusion

Clinical Effect of the Treatment of Lumbar Intervertebral Disc Protrusion.

Compared with traditional acupuncture, it is urgently needed for more effective method for the disease to serve the clinical treatment. This paper combines acupuncture and massage to treat lumbar intervertebral disc protrusion, uses a controlled trial to study the clinical effects of acupuncture combined with massage for the treatment of lumbar intervertebral disc protrusion, combines mathematical statistics to test the data, and compares and analyzes the statistical object parameters. Through experimental research, it is known that in the treatment of lumbar intervertebral disc protrusion, in order to obtain a faster and better effect, traditional acupuncture treatment should be combined with massage therapy. On the basis of fully eliminating the pathological factors, the intervertebral disc is reset by mechanical treatment, which makes the patient more likely to heal. Therefore, it is a comprehensive treatment plan that is worth adopting.

Three-Dimensional Biomechanical Finite Element Analysis of Lumbar Disc Herniation in Middle Aged and Elderly.

Lumbar intervertebral disc protrusion disease refers to the degeneration of intervertebral disc, rupture of fibrous ring, nucleus pulpous protrusion and stimulation or compression of nerve root. The import command in Mimics medical 3D reconstruction software was used to erase the irrelevant image data and obtain vertebral body images. The original 3D model of each vertebral body was built by 3D computing function. A three-dimensional finite element model was established to analyze the effect of different surgical methods on the mechanical distribution of the spine after disentomb. The stress distribution of the spine, intervertebral disc, and left and right articular cartilage at L4/L5 stage and the position shift of the fourth lumbar vertebra were analyzed under 7 working conditions of vertical, forward flexion, extension, left and right flexion, and left and right rotation. The results showed that the established model was effective, and the smaller the area of posterior laminar decompression was, the lesser the impact on spinal stability was. The PELD treatment of lumbar disc herniation had little impact on spinal biomechanics and could achieve good long-term biomechanical stability. Combining the clinical experiment method and finite element simulation, using the advantages of finite element software to optimize the design function can provide guidance for the design and improvement of medical devices and has important significance for the study of clinical mechanical properties and biomechanics.

Study on Mongolian Medical Nursing Care of Patients with Lumbar Intervertebral Disc Protrusion

Study on Mongolian Medical Nursing Care of Patients with Lumbar Intervertebral Disc Protrusion

Treatment of protrusion of Lumbar Intervertebral Disc (LID) with percutaneous laser disc decompression - a follow-up study of 108 patients

To study the long-term clinical efficacy of protrusion of lumbar intervertebral disc with percutaneous laser disc decompression (PLDD). A statistics was conducted on 108 patients who had been treated with percutaneous laser disc decompression, the intervertebral height of related lesion spaces of patients in different time points after treatment and the intervertebral height ratio was calculated respectively; moreover, a statistics was conducted on VAS evaluation of patients in different time points, and the long-term efficacy after treatment with percutaneous laser disc decompression was evaluated with statistical method. The patients with follow-up period after operation respectively up to 5, 8 and 10 years and those in 3 years after operation were analyzed statistically in intervertebral height ratio and VAS scoring, and the difference was without significant statistical significance. Single-factor was analyzed to the factors likely to influence the effect of operation to get the authenticity of influence of age, disease duration and disease stage on the postoperative efficacy. Percutaneous laser disc decompression was featured by safety, efficacy and fewer complications in treatment of protrusion of lumbar intervertebral disc, and also it had no obvious influence on the spinal stability, and long-term postoperative efficacy was stable.

Acupotomy Treatment for Lumbar Disc Herniation

Background: The aim of this study was to examine whether the effects of acupotomy therapy were beneficial for the treatment of protrusion of lumbar intervertebral disc.<br/>Methods: The number of patients (n = 80) were equally assigned into treatment group and control group. Treatment group was given acupotomy therapy twice a week, and control group was given acupuncture 3 times a week, for 4 weeks. The beneficial effect and changes in score of the Japan Orthopedic Association (JOA) for low back pain were observed.<br/>Results: Among 40 cases in the treatment group, there were 25 (62.5%) with an excellent effect, 13 (32.5%) with good effect, 1 (2.5%) with a medium effect and 1 (2.5%) with poor effect, with the total experiencing an excellent/good effect of 95.0%. Among 40 cases in the control group, there were 11 (27.5%) with an excellent effect, 17 (42.5%) with good effect, 10 (25.0%) with a medium effect, and 2 (5.0%) with poor effect, with an excellent/good rate of 70.0%. The result of the rank sum test showed Z = -4.923, p < 0.05 in the comparison, indicating a significantly better outcome following acupotomy compared with acupuncture. JOA scores increased in both groups after treatment (p < 0.05), which was more significant in the acupotomy treatment group (p < 0.05).<br/>Conclusion: Acupotomy therapy has a beneficial effect on protrusion of lumbar intervertebral disc.

Biomechanical Comparison of Lumbar Fixed-Point Oblique Pulling Manipulation and Traditional Oblique Pulling Manipulation in Treating Lumbar Intervertebral Disk Protrusion

ObjectiveTo compare the biomechanical effect of lumbar fixed-point oblique pulling manipulation and traditional oblique pulling manipulation in the treatment of protrusion of lumbar intervertebral disk, and investigate the influence of disk degeneration on the 2 manipulations. MethodsThree finite element models including 1 normal model, 1 mild degeneration, and 1 moderate degeneration model of L3-S1 were developed to simulate 2 oblique pulling manipulations. The disk protrusion was assumed to be in the left central and subarticular zone of the L4-L5 disk, and manipulations were carried out on the right. A 15-Nm right axial rotation moment and 150-N compressive loading were imposed on the upper endplate of L3 to simulate a traditional oblique pulling manipulation. To simulate lumbar fixed-point oblique pulling manipulation, in addition to a 15-Nm moment and 150-N compressive loading imposed on the L3 upper endplate, a 50-N force was imposed on the right lateral area of the L4 spinous process in a left front direction. The displacement and stress in the left central and subarticular zone of the L4-L5 disk were calculated and compared in the 3 models. ResultsThe average displacement and stress in the left central and subarticular zone of L4-L5 disk were higher in fixed-point oblique pulling manipulation than those in traditional oblique pulling manipulation (P < .05). In addition, the values of average stress and displacement decreased significantly with the increase of lumbar disk degeneration (P < .05). ConclusionLumbar fixed-point oblique pulling manipulation showed a better biomechanical effect than traditional oblique pulling manipulation, and lumbar disk degeneration affected the 2 manipulations adversely in the virtual treatment of protrusion of the lumbar intervertebral disk using finite element models.

DIAGNOSTIC RADIOLOGY METHODS OF DEGENERATIVE CHANGES IN LUMBAR INTERVERTEBRAL DISCS IN YOUNG PEOPLE

In recent years, the number of scientific studies investigating the prevalence of low back pain among schoolchildren has been significantly increased. Degenerative disease of the discs is often accompanied by a low back pain with irradiation into the legs in representatives of different age groups, in particular, in older children. The main factors of its development are genetic predisposition, trauma, obesity, lack of exercise. Most of the components of the vertebral motor segment have the nerve endings and reflex influences, accompanied by inflammation, microcirculatory disorders, and their combination contributes to an appearance of back pain. Diagnosis of degenerative disc disease includes the study of the patient's medical history, analysis of clinical symptoms, use of functional tests and various types of imaging to clarify the degree of macrostructural changes in disks, among which the main place is taken by the magnetic resonance imaging. The development of degenerative changes in intervertebral discs as early as childhood, which requires a further study using non−invasive, accessible and informative methods, especially ultrasound ones. The results of ultrasonography of lumbar intervertebral discs were analyzed in 36 adolescents aged 16−18 years, diagnosed for the protrusion when the MRI was applied. Paramedian protrusion was found to be significantly more frequent than posterolateral, median, and circular ones. Due to its non−invasiveness, low price and information value, the ultrasound can be the most popular method not only as a screening one but also for the expert evaluation of lumbar intervertebral disc protrusion in schoolchildren. Key words: diagnostic radiology, lumbar intervertebral discs, adolescents.

Endoscopic removal of nucleus pulposus of intervertebral disc on lumbar intervertebral disc protrusion and the influence on inflammatory factors and immune function.

Endoscopic removal of nucleus pulposus (NP) of intervertebral disc (IVD) on lumbar intervertebral disc protrusion (LIDP) and its influence on inflammatory factors and immune function were explored. A total of 145 patients with LIDP admitted to The First Affiliated Hospital of Bengbu Medical College from June 2017 to December 2018 were selected and electively treated, in which 87 patients were treated with fenestration discectomy (fenestration group) and 58 patients were treated with endoscopic removal of NP of IVD (minimally invasive group). Effects on patients in the two groups within 6 months after surgery were evaluated by modified MacNab score; differences in surgical related indexes and incidence rates of complications between the two groups were compared; the Oswestry dysfunction score and VAS pain score before treatment, and 1, 3 and 6 months after treatment, and changes of cellular levels of TNF-α, IL-4, IL-6, CD3+, CD4+, and CD8+ before treatment, and 24 and 48 h after surgery were evaluated. Length of surgical incision, intraoperative blood loss, time of operation, time in bed, and hospital stays of patients in minimally invasive group were lower than those in the fenestration group (P<0.05). The Oswestry score and VAS score of patients in minimally invasive group 1, 3 and 6 months after surgery were lower than those in fenestration group (P<0.05). The incidence rate of spinal instability and overall incidence of complications of patients in minimally invasive group were significantly lower than those in fenestration group (P<0.05). Levels of TNF-α and IL-6 of patients in the minimally invasive group 24 and 48 h after surgery were lower than those in the fenestration group (P<0.05) and cellular levels of IL-4, CD3+, CD4+, and CD8+ were higher (P<0.05). In conclusion, endoscopic removal of NP of IVD has good therapeutic effects in patients with LIDP. It reduces inflammation and suppresses immune function with higher safety, worthwhile for clinical use.

Lumbar Transforaminal Epidural Steroid Injection in Patients with Lumbar Radicular Pain; Outcome Results of 2-Year Follow-Up.

Objective:To evaluate the effectiveness of transforaminal lumbar epidural steroid injections (TFESI) in patients with unilateral radiculopathy due to lumbar intervertebral disc protrusion regarding pain intensity, functional disability, current opioid intake and patients’ satisfaction. Methods:The study is conducted in a pain management center (Tehran, Iran), during 2018. Inclusion criteria were age ≥18 years, radiculopathy for more than 6 months due to imagine-proved lumbar intervertebral disc protrusion and no response to conservative treatments. Exclusion criteria were spinal canal stenosis, lumbar surgery, and inability to communicate in Persian language. During a phone call interview, cases were instructed to rate their pain intensity according to the visual analogue scale (VAS), functional ability, satisfaction according to the patient satisfaction score (PSQ) and report current opioid use and additional injection and/or surgery. Results:Forty-three (89.5%) of the 48 subjects were reachable for study with mean age of 59.14 years and 16 subjects were men (37.2 %). Mean VAS after intervention was 4.67 and before the intervention was 6.91 (p=0.002). Mean functional disability before intervention was 47.23 and after intervention was 37 (p<0.001). Mean patient satisfaction score was 3.07 while 18 cases reported a PSQ level ≥4. 10 cases reported using opioid for analgesia, 23 cases reported receiving additional TFESIs and 11 reported having undergone lumbar surgery.Conclusion:Lumbar Epidural steroid injection is an effective non-surgical treatment option with regard to pain relief and improvement in functional ability with an average patients’ satisfaction during 2 years follow up although nearly 25% of patients may need additional injections and half of the patients may finally proceed to surgery.

Applications Research of Cluster Analysis in Chinese Acupuncture Therapy

It is significant to improve the clinical therapeutic effect of Chinese acupuncture for an acupuncturist. Cluster analysis can classify the patient samples and help the acupuncturist to innovate the traditional acupuncture therapy under the concept of personalized treatment. This paper points out the concrete steps of the cluster analysis application in the improvement of the treatment effect of Chinese acupuncture, which incudes indexes selection, data collection and clustering analysis. Then, the paper provides a concrete case of cluster analysis application for thirty patients of lumbar intervertebral disc protrusion. We divided the patients into three categories and adopt different types of patients with different acupuncture treatment to achieve good treatment results.

Treatment of displacement-type lumbar intervertebral disc protrusion on L2-L5 with percutaneous endoscopic interlaminar discectomy

To evaluate the operative characteristic, safety, clinical effect of percutaneous endoscopic interlaminar discectomy (PEID) in treating displacement-type lumbar intervertebral disc protrusion on L₂-L₅. Form November 2015 to October 2016, 15 patients with displacement-type lumbar intervertebral disc protrusion were treated with percutaneous endoscopic interlaminar discectomy. There were 9 males and 6 females, aged from 19 to 63 years old with an average of 42 years. All the patients with single-segment displacement-type lumbar intervertebral disc protrusion were diagnosed by clinical and iconography data, and complicated with low back pain and single lower limbs radioactivity pain. Lesion occurred in L₄,₅ of 8 cases, L₃,₄ of 4 cases, L₂,₃ of 3 cases. The patients were divided into 4 regions according to Lee standard (displaced nucleus pulposus location on spinal canal), I region was 2 cases, II region was 3 cases, III region was 5 cases, IV region was 5 cases.Preoperative, postoperative 3 months, final follow-up, lumbago-leg pain and lumbar function were assessed by VAS, JOA scores;at final follow-up, MacNab was used to evaluate the clinical effect;postoperative 3 months, rechecked lumbar MRI to observe discectomy condition. All the operations were successfully complete under local anesthesia, and no complications such as injuries of nerve root and dural sac, postoperative hemorrhage, local infection were found. Operative time was 45 to 90 min with an average of 54.8 min;and hospitalization time was 3 to 4 days with an average of 3 days. All 15 cases were followed up for 12 to 13 months with an average of 12.2 months, no recurrence was found. Preoperation, postoperative 3, 12 months, VAS scores were 8.2±1.4, 3.0±0.6, 1.7±0.5, JOA scores were 8.76±3.32, 23.61±2.14, 24.82±3.43, respectively. Postoperative VAS, JOA scores were obviously improved(P<0.05). According to MacNab standard to evaluate the clinical effect, 9 cases obtained excellent results, 5 good, 1 fair. PEID is a micro-trauma surgical method and has advantage of safe and effective in treating displacement-type lumbar intervertebral disc protrusion on L₂-L₅, but requires laminoplasty during operation, and under local anesthesia to operation maybe can induce neurostimulation.

THE EFFICACY OF OZONE THERAPY ON DIFFERENT TYPES OF LUMBAR DISC HERNIATION: PROPOSAL FOR GUIDANCE UPDATES

Objective: To explore the possible mechanisms of pain relief by ozone therapy in patients with different types of lumbar intervertebral disc protrusion.&#x0D; Methods: The medical records of a total of 250 patients with protrusion of lumbar intervertebral disc (159 males, 91 females, aged 14–85 years) admitted in the South Hospital from January 2009 to June 2014 were retrospectively reviewed. Patients with protrusion of lumbar intervertebral disc were divided into four groups according to T2-weighted magnetic resonance imaging and digital subtraction angiography findings during ozone injection: type I, fibrous ring rupture without nucleus pulposus protrusion; type II, fibrous ring rupture with nucleus pulposus protrusion; type III, non-ruptured fibrous ring without nucleus pulposus protrusion; and type IV, non-ruptured fibrous ring with nucleus pulposus protrusion. Visual analogue scale (VAS) pain scores were used to evaluate treatment efficacy among patients with different types of lumbar intervertebral disc protrusion before surgery, and at 1 week, 1 month, 6 months, and 12 months after surgery.&#x0D; Results: Atrophy of the nucleus pulposus was observed in 63% of type II and IV patients within 1 year after surgery. The VAS scores at 1 week, 1 month, 6 months, and 12 months after surgery decreased by an average of 4.47, 4.41, 4.77, and 4.85 for type I to IV disease, respectively. More specifically, scores of type I patients were decreased by 4.57, 4.72, 4.98, and 4.93, respectively, during the follow-up period. Scores of type II patients were decreased by 4.78, 461, 5.08, and 5; type III cases by 3.72, 377, 3.97, and 4.84, respectively; and type IV cases by 4.24, 4.10, 4.45, and 4.41, respectively. In addition, the postoperative VAS score of 94.4%, 91.6%, 89.6% and 90.8% of patients were decreased by &gt; 25%, i.e., the pain was alleviated, with type I patients demonstrating a pain relief rate of 96.3% during the entire follow-up period, along with 93.5% and 89.8%, and 89.8%, respectively for type II patients, 76.9%, 84.6%, 76.9%, and 87.2%, respectively for type III patients, and 77.6%, 79.6%, 79.6%, and 79.6%, respectively for type IV patients.&#x0D; Conclusion: Ozone therapy is an effective pain-relief therapy for lumbar intervertebral disc protrusion. The degree of pain relief was closely related to rupture of the fibrous ring and protrusion of the nucleus pulposus. Pain relief efficacy was improved in patients with fibrous ring rupture and nucleus pulposus, while the pain relief effects in patients without fibrous ring rupture or nucleus pulposus protrusion were poor.

Efficacy of high intensity laser therapy in treatment of patients with lumbar disc protrusion: A randomized controlled trial.

This study aims to evaluate the effect of high intensity laser therapy (HILT) in patients with lumbar disc protrusion (LDP). This study included 63 patients suffering from protrusion of lumbar intervertebral disc; they were divided into Groups 1 (n= 32) and 2 (n= 31). Group 1 was treated with HILT and spinal decompression system (SDS). Patients in Group 2 received SDS alone. Evaluations were conducted on oswestry disability index (ODI), lumbosacral portion pain, and lower limb radiation pain with visual analogue scale (VAS) of two patient groups before treatment, two weeks after treatment, and 1 month after follow-up visit. Lumbar flexion range and angle of straight leg raising before treatment and 2 weeks after treatment. After two weeks of treatment of two patient groups, ODI, VAS, lumbar flexion range and angle of straight leg raising significantly improved compared with their conditions before treatment (P< 0.01). A significant difference was noted in ODI, lumbar flexion range, and angle of straight leg raising between groups after two weeks of treatment (P< 0.05). Non-statistical significant difference was observed in lumbosacral portion pain and lower limb radiation pain with VAS (P> 0.05). However, difference in was VAS smaller in Group 1. All groups showed significantly different results in terms of ODI, lumbosacral portion pain, and lower limb radiation pain with VAS. As one of available treatments for LDP, HILT can speed up improvement in lumbar segment motion, angle of straight leg raising, and overall function and allow early return of patients to their family and society. Treatment effect is long-lasting and can be widely promoted and applied clinically.

Influence of endoscopic lumbar discectomy on limb function and quality of life in patients with lumbar intervertebral disc protrusion

Objective To explore and analyze the influence of endoscopic lumbar discectomy on limb function and quality of life in patients with lumbar disc prolapse. Methods 90 cases of lumbar intervertebral disc protrusion were selected, and they were divided into control group and observation group according to the operation method, 45 cases in each group.The control group was given open lumbar disc excision treatment, the observation group was given percutaneous endoscopic lumbar disc resection treatment.The perioperative therapeutic index, physical function and quality of life were compared between the two groups. Results The intraoperative blood loss, time in bed, hospital stay, postoperative VAS score of the control group were (60.21±20.32)min, (30.36±14.25)mL, (26.96±9.69)d, (8.21±2.36)d, (5.12±1.36)points, respectively, which of the observation group were (58.96±19.88)min, (12.88±10.28)mL, (100.69±18.75)d, (12.99±3.88)d, (1.98±0.33)points, respectively.Compared with the control group, the observation group had less intraoperative blood loss, shorter time in bed, shorter hospital stay, lower postoperative VAS score, the differences were statistically significant (t=4.25, 4.66, 5.12, 5.78, 6.12, all P 0.05). After treatment, the physical function, role function, emotional function, cognitive function and social function score of the control group were (7.89±0.78)points, (7.99±1.25)points, (7.84±0.65)points, (7.65±0.75)points, (7.45±0.77)points respectively, which of the observation group were (8.96±1.78)points, (8.75±1.12)points, (8.56±0.88)points, (8.42±0.66)points, (8.56±1.47)points, respectively.Compared with before treatment, the physical function, role function, emotional function, cognitive function and social function score in the two groups after treatment were higher.After treatment, compared with the control group, the scores increased more significantly in the observation group (t=6.55, 7.56, 7.88, 7.56, 7.89, all P<0.05). Conclusion Endoscopic resection and open lumbar disc excision technique in treatment of patients with lumbar intervertebral disc protrusion of lumbar can obtain similar curative effect, but the former has less incision, less intraoperative blood loss, postoperative recovery fast, can better improve the patients′ quality of life. Key words: Lumbar disc disease; Lumbar disc excision; Limb function; The quality of life

Percataneous endoscopic lumbar discectomy for the treatment of lumbar intervertebral disc protrusion

To explore the clinical effects of percataneous endoscopic lumbar discectomy for lumbar intervertebral disc protrusion. The clinical data of 46 patients with lumbar intervertebral disc protrusion underwent percataneous endoscopic lumbar discectomy were retrospectively analyzed. There were 21 males and 25 females, aged from 23 to 65 years old with an average of 42 years. The course of disease was from 5 to 87 months with an average of 13.4 months. Protrusion located in L₂,₃ of 2 cases, L₃,₄ of 3 cases, L₄,₅ of 28 cases, L₅S₁ of 13 cases. There were 5 patients with central type, 34 with para-side type, 7 with extreme lateral type. VAS, ODI and JOA scores were used to analyze the condition of pain releasing and lumbar functional improvement. According to MacNab standard to evaluate the clinical effect at final follow-up. All the operations were successful, operative time was 125 to 210 min with a mean of 153.6 min; and all the patients were follow-up for 6 to 12 months with an average of 8 months; no injuries of nerve and blood vessel, infection were found. Postoperative 3 days and final follow-up, VAS score was 3.1±0.7, 2.2±0.6 respectively, and was obviously lower than preoperative 7.3±1.2(P<0.05). At final follow-up, JOA and ODI were (23.5±2.4) points, and (22.10±9.26)%, respectively, and was obviously improved compared with preoperative (13.2±2.8) points and (69.12±13.15)% (P<0.05). According to modified MacNab standard to evaluate the clinical outcome, 30 cases got excellent results, 14 good, 2 fair, no recurred and overhauling were found. Percataneous endoscopic lumbar discectomy is a minimally invasive technique, with advantage of safety and effectiveness, and apply to treatment of lumbar intervertebral disc protrusion.

Comparison of the effects of different percutaneous endoscopic removal of nucleus pulposus by vertebral plate gap into the road in the treatment of L5 and S1 lumbar intervertebral disc protrusion

Objective To compare the clinical effect of different percutaneous endoscopic removal of nucleus pulposus vertebral plate gap into the road in the treatment of L5 and S1 lumbar intervertebral disc protrusion. Methods 120 cases with lumbar intervertebral disc protrusion in our hospital were randomly divided into group A and group B, 60 cases in each group.Group A was given the intervertebral foramen mirror vertebral plate gap into the way, group B was given the posterior intervertebral disc mirror reserves the yellow ligament treatment.The operation time, number of perspective, intraoperative blood loss, length of incision, visual analogue scale (VAS), hospitalization days, Oswestey disability index (ODI) before and after surgery were compared between two groups. The curative effect was evaluated by the Macnab criteria. Results The operation time, number of perspectives, intraoperative blood loss, surgical incision length, VAS score, hospitalization days in group A were (58.69±5.26)min, (2.56±0.52)times, (80.23±20.45)mL, (1.63±0.33)cm, (2.95±0.77)points, (4.98±0.84)d, respectively, those in group B were (60.36±5.31)min, (2.55±0.48)times, (75.69±2.96)mL, (1.56±0.21)cm, (2.98±0.69)points, (5.01±0.86)d, the differences between the two groups were not significant (all P>0.05). Immediate postoperation and postoperative 3 months, the ODI scores of group A were (36.96±10.58)points, (9.26±0.23)points, (6.35±0.44)points, respectively, and those of group B were (37.02±9.85)points, (9.42±0.65)points, (6.30±0.39)points, immediately after operation, postoperative 3 months, the ODI scores of the two groups were lower than before operation, compared with immediate postoperation, the ODI scores of postoperative 3 months were significantly reduced, the difference was statistically significant (P 0.05). The excellent rate of group A was 90.00%, which of group B was 91.67%, the difference between the two groups was not obvious (P>0.05). Conclusion Intervertebral foramen mirror the vertebral plate gap into the road and posterior intervertebral disc mirror reserves are yellow ligament in treatment of L5 and S1 lumbar intervertebral disc protrusion will achieve good operation effect, no obvious difference was found between the two methods, before undergoing surgery for the patients' individual condition and indications for judgment, and to choose appropriate surgical method. Key words: Intervertebral disk displacement; Discectomy, percutaneous; Surgical procedures, minimally invasive

A case-control study on the treatment of protrusion of lumbar intervertebral disc through PELD and MED.

We compared the clinical effects between the percutaneous endoscopic lumbar discectomy (PELD) and microendoscopic discectomy (MED) treatments for protrusion of lumbar intervertebral disc. We conducted a retrospective analysis on 60 patients who were diagnosed with single-segment protrusion of lumbar intervertebral disc during the period from January 2009 to June 2016. Patients were divided into two groups, the PELD and MED groups, which contained 30 cases each. We evaluated the operation results according to oswestry dysfunction index (ODI), visual analogue scale (VAS) and the improved MacNab standard. The average follow-up visit period after the operation was 18 months and the operation time of the two groups was not statistically different. The cadaverine quantity of bleeding in the PELD group is less than that in the MED group. Moreover, the average length of incision and the length of stay were shortened for the PELD group compared to the MED group. The ODI and VAS after operation for the two groups improved significantly compared to that before operation (P<0.05). The qualified rates of the PELD and MED groups were 93.0 and 90.0%, respectively, as of the improved MacNab method. The complication occurrence rates for the two groups during perioperative period were not different. Therefore, the short-term efficacy of the two minimally invasive operation methods (PELD and MED) on the treatment of protrusion of lumbar intervertebral disc is satisfactory. In cases where operation indications are chosen strictly, PELD can be regarded as a method of safety and efficiency due to the advantages of minimal incision, less bleeding, minimal trauma and faster postoperative recovery.

Clinical analysis of cervus and cucumis polypeptide injection for lumbar vertebrae diseases based on real world hospital information system

To analyze the clinical drug use characteristics and medication rules of cervus and cucumis polypeptide injection (CCP injection) for the patients with lumbar vertebra diseases. Based on the electronic medical data of 6 990 patients with CCP injection for lumbar vertebra diseases from 25 first-class hospitals over the whole country from 2004, statistical analysis was conducted for their general information, diagnostic information, orders information, laboratory test information and treatment results. The results showed that the age distribution was highest in patients aged 45 to 64 (3 883, 55.55%); protrusion of lumbar intervertebral disc was most common among lumbar vertebra diseases (5 519, 82.50%); and TCM syndrome mainly included hemostasis. The daily dose was most between 8-12 mL, with a usual treatment course of 1-3 d. Commonly used western medicines in combined drug use included hypertonic dehydrating agent, antibiotics and nutrition nerve medicines, and the commonly used traditional Chinese medicines in combined drug use included the drugs with promoting blood circulation to remove blood stasis, kidney-tonifying and bone-building agents, and formula for clearing heat and removing toxicity, etc. The most commonly used western medicines are methylamine, adenosine, lidocaine injection, mannitol, et al, and the most commonly used Chinese medicines included Jintiange capsules, Qianggu capsules, et al. It is suggested that CCP injection for lumbar vertebrae diseases is mainly used in middle-aged and elderly patients, and is frequently used in combination with kidney-tonifying and bone-building agents, drugs with promoting blood circulation to remove blood stasis, analgesic agents and antibiotics.

Surgical Technique of Excision of Lumbar Intervertebral Disk Protrusion

Surgical Technique of Excision of Lumbar Intervertebral Disk Protrusion