Senior Clubs are the most commonly available and, in most cases, free form of activation of older people. The aim of their functioning is improvement in the quality of life of seniors through education and activation. By using research tools to assess the needs of seniors it is possible to determine the direction of intervention related with an effective therapeutic, educational and activation procedures. An individual approach to seniors seems to be the key to knowing their real needs, which significantly determine the quality of life, and may also help limit the escalation of gerontophobia occurring in the society. Research was conducted among participants in Senior Clubs and Universities of the Third Age. The aim of the study was verification of the needs, expectations, and potential barriers faced by seniors at the time of the SARS-CoV-2 pandemic. The basic tool used in the study was an author-constructed, anonymous questionnaire including items from the standardized European Health Literacy Survey Questionnaire (HLS-EU-Q47). Participation in the survey was voluntary, and the selection criterion was participation in meetings of senior organisations located in the Lublin Province of eastern Poland. The study showed that the distance between the place of residence of seniors and the location of senior institutions was the factor determining participation in the classes. In addition, during the period of sanitary regime the seniors had increased difficulties with access to medical care and medical specialists. Senior institutions and organizations should consider the needs of seniors and adjust their offer to the challenges resulting from the period of social isolation.