Lower Blood Sugar Levels Research Articles

Comparison of medication adherence in patients with type 2 diabetes mellitus: a pre and post study

Background: Type 2 diabetes mellitus refers to a group of heterogeneous disorders with the common elements of chronic hyperglycemia. Diabetes medications play a crucial role in lowering blood sugar levels. The study aims to compare medication adherence in patients with type 2 diabetes mellitus from urban and rural areas during pre and post visit. Methods: This pre and post-study was conducted from March to August 2022. A total of 104 participants were enrolled. Details have been obtained through data collection form. Medication adherence was measured using Hill-Bone medication adherence scale, and patient education was provided through leaflet. Results: The study included 54 females and 50 males. The correlation between medication adherence versus disease knowledge and drug knowledge was found out using Pearson’s correlation and the result is statistically significant. The medication adherence was found to be increased by 17.3% and 21.2% in rural and urban areas respectively. Inadequate follow-up and financial barriers were most accounted for medication non-adherence. Conclusions: The majority of type 2 diabetes patients have suboptimal treatment adherence which is associated with poor blood sugar control. We clinical pharmacists can tackle this problem of adherence through quality patient education.

PERBEDAAN PENURUNAN KADAR GULA DARAH PADA PENDERITA DIABETES MELLITUS TIPE II DENGAN PEMBERIAN RELAKSASI OTOT PROGRESIF DAN SENAM KAKI DIABETES

Diabetes mellitus a serious chronic disease, which the pancreas is unable to produce insulin in the body, but it can also occur if the body is not effective in using the insulin produces. One of the non-pharmacological management of diabetes mellitus is progressive muscle relaxation and diabetic foot exercise. purpose of the Research: Analyze the difference in the effect of progressive muscle relaxation and foot exercises on reducing blood sugar patients with type II diabetes mellitus.Research methodology: The study used the Quasi Experimental Design method with a Static Group Comparison Design. The sample of this study was type II diabetes mellitus in the Sidoharjo Health Center, Sragen, as many as 56 respondents. Sampling using purposive sampling technique. Results: The results of the Independent Sample T-Test on progressive muscle relaxation and diabetic foot exercises showed Sig. (2-tailed) p = 0.777 where p value > 0.05. Discussin, Progressive muscle relaxation and diabetic foot exercises can be a complementary therapy to diet and pharmacology to help lower blood sugar levels. Conclusions: There is no significant difference between progressive muscle relaxation therapy and diabetic foot exercises in reducing blood sugar levels in type II diabetes mellitus patients

Glucagon-Like Peptide-1 (GLP-1) during Ramadan: Narrative Review of the Published Literature.

Ramadan fasting, a religious practice observed by Muslims worldwide, involves abstaining from eating, drinking, smoking, and using oral medications from dawn to dusk during the ninth lunar month. Studies have demonstrated that fasting during Ramadan has been shown to increase HDL cholesterol, leptin, adiponectin, and insulin sensitivity, as well as lower several hemostatic risk factors for cardiovascular diseases. Additionally, it may result in a drop in blood sugar levels, especially in diabetics who are also on blood sugar-lowering medicine. Hypoglycemia, characterized by low blood sugar levels, could also result from fasting during Ramadan. The GLP-1 (glucagon-like peptide-1) hormone plays a significant role in regulating glucose metabolism and insulin secretion, and Ramadan fasting can affect its production and release in the gut. Research contributes to our understanding of the utilization of GL-1 medications during Ramadan among patients, broadening therapy alternatives and offering insightful information for well-informed decision-making. Therefore, this narrative review aims to explore the current evidence that studies the safety and efficacy of GLP-1 agonists during Ramadan for nondiabetic and diabetic patients to ensure healthy fasting during Ramadan.

Anti-Diabetic Cure Plants In Sungai Kijang Pride

Diabetes Mellitus (DM) is a disease caused by a lack of the hormone insulin and generally consumes medication using chemical drugs due to the fast response in lowering blood sugar levels. However, the use of chemical drugs in the long term can have a negative impact on kidney performance. The way to minimize the negative impact is to use plants as medicine with the following considerations, that is: easy to obtain and minimal side effects. The tribe in Musi Rawas Utara Regency who still maintains the use of plants as medicine as a hereditary inheritance from their ancestors, namely the Anak Dalam Sungai Kijang Tribe in Sungai Kijang Village, Rawas Ulu District, so it is important to inform the wider community regarding this matter. The specific objectives of the study were to describe the types of medicinal plants, to describe the parts of the plants used, and to describe the processing methods for medicinal plants that have anti-diabetic potential. This research method focuses on the types, parts used, and ways of processing medicinal plants with potential anti-dibates for the Anak Dalam Sungai Kijang Tribe. Retrieval of data using observation sheets, questionnaires, interviews, and documentation. The data analysis used is descriptive with a qualitative approach. The results showed 14 types, namely Marasi, Plant Risih, Akar Timah, Pasak Bumi, Kratom, Akar Kuning, Sekubung, Mendururat, Kemeran, Lenteman, Passion, Okinawa Spinach, Kerisan, and Gembili. The organs used are stems, leaves, tubers, and roots. The processing method is washed, eaten immediately, cut, boiled, dropped into the eyes, drunk, and cleaned of the skin. Based on these results it can be concluded that nature always provides what is needed and that is the main principle of the Anak Dalam Sungai Kijang Tribe.

Purple Napiergrass (Pennisetum purpureum Schumach) Hot Water Extracts Ameliorate High-Fat Diet-Induced Obesity and Metabolic Disorders in Mice.

Purple Pennisetum (Pennisetum purpureum Schumach), a hybrid between Taihucao No. 2 and the local wild species of purple Pennisetum, has dark red stems and leaves due to its anthocyanin content. This study explores the potential of purple napiergrass extracts (PNE) in alleviating obesity and metabolic disorders induced by a high-fat diet in mice, where 50% of the caloric content is derived from fat. Mice were orally administered low-dose or high-dose PNE alongside a high-fat diet. Experimental findings indicate that PNE attenuated weight gain, reduced liver, and adipose tissue weight, and lowered blood cholesterol, triglyceride, low-density lipoprotein, and blood sugar levels. Stained sections showed that PNE inhibited lipid accumulation and fat hypertrophy in the liver. Immunoblotting analysis suggested that PNE improved the inflammatory response associated with obesity, dyslipidemia, and hyperglycemia induced by a high-fat diet. Furthermore, PNE potentially functions as a PPAR-γ agonist, increasing the adiponectin (ADIPOQ) concentration and suppressing inflammatory factors, while elevating the anti-inflammatory factor interleukin-10 (IL-10) in the liver. PNE-treated mice showed enhanced activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt) and AMP-activated protein kinase (AMPK) pathways and increased fatty acid oxidation and liver lipolysis. In conclusion, this study elucidated the mechanisms underlying the anti-inflammatory, PI3K/Akt, and AMPK pathways in a high-fat diet-induced obesity model. These findings highlight the potential of PNE in reducing weight, inhibiting inflammation, and improving blood sugar and lipid levels, showing the potential for addressing obesity-related metabolic disorders in humans.

The effect of metformin on senescence of T lymphocytes

BackgroundImmunosenescence occurs as people age, leading to an increased incidence of age-related diseases. The number of senescent T cells also rises with age. T cell senescence and immune response dysfunction can result in a decline in immune function, especially in anti-tumor immune responses. Metformin has been shown to have various beneficial effects on health, such as lowering blood sugar levels, reducing the risk of cancer development, and slowing down the aging process. However, the immunomodulatory effects of metformin on senescent T cells still need to be investigated.MethodsPBMCs isolation from different age population (n = 88); Flow Cytometry is applied to determine the phenotypic characterization of senescent T lymphocytes; intracellular staining is applied to determine the function of senescent T cells; Enzyme-Linked Immunosorbent Assay (ELISA) is employed to test the telomerase concentration. The RNA-seq analysis of gene expression associated with T cell senescence.ResultsThe middle-aged group had the highest proportion of senescent T cells. We found that metformin could decrease the number of CD8 + senescent T cells. Metformin affects the secretion of SASP, inhibiting the secretion of IFN-γ in CD8 + senescent T cells. Furthermore, metformin treatment restrained the production of the proinflammatory cytokine IL-6 in lymphocytes. Metformin had minimal effects on Granzyme B secretion in senescent T cells, but it promoted the production of TNF-α in senescent T cells. Additionally, metformin increased the concentration of telomerase and the frequency of undifferentiated T cells. The results of RNA-seq showed that metformin promoted the expression of genes related to stemness and telomerase activity, while inhibiting the expression of DNA damage-associated genes.ConclusionOur findings reveal that metformin could inhibit T cell senescence in terms of cell number, effector function, telomerase content and gene expression in middle-aged individuals, which may serve as a promising approach for preventing age-related diseases in this population.

Test the Effectiveness of Grape Seed Extract as an Antidiabetic Drug In Male White Rats Wistar Strain

The research aims to know the effectiveness of grape seeds in lowering blood sugar levels in white rats. The research began with grape seed extraction using the maceration method. The results of macerate were given to white rats that were given grape seed extract samples at doses of 75 mg/200 grams BW, 125 mg/200 grams BW, and 250 mg/200 grams BW. The positive control was metformin, and the negative control was given distilled water. All were given treatment for 14 days. On days seven and 14, a blood sugar test was carried out to assess the effectiveness of grape seed extract. The results showed that of the five treatment groups, sample group I (extract at a dose of 75 mg/200 gram BW) and sample group III (extract at a dose of 250 mg/200 gram BW) affected reducing blood sugar levels in rats. This is proven by comparing blood sugar levels after being given alloxan on the seventh day in the two groups, showing better results in reducing blood sugar levels than the other groups. It can be concluded that grape seed extract can properly reduce blood sugar levels in white rats with type II diabetes mellitus.

Application of Combined Self-Surrender Exercises and Deep Breath Relaxation to Lower Blood Sugar Levels Elderly Diabetes Mellitus Type

Diabetes is already considered an epidemic and by 2025, it is estimated that around 380 million people, or 7.3% of the adult population in the world will be affected by this disease Diabetes Atlas 2012 (International Diabetes Federation) lists that the estimated population of Indonesia over 20-79 years is 7.6 million people and the assumption of DM prevalence is 5.14%. Indonesia ranks 8th largest in the number of people with diabetes mellitus. The order above is China (92.3 million), India (63.0 million), the United States (24.1 million), Brazil (13.6 million), the Russian Federation (12.7 million), and Mexico (10.6 million). Problems faced by elderly Posyandu participants In the working area of the Kerinjing Health Center, Kerinjing Village, Ogan Ilir Regency, Palembang.: Never received information about Diabetes Mellitus and non-pharmacological management, especially the combination of self-surrender exercises with deep breath relaxation to lower blood sugar in the elderly with Diabetes Mellitus, Never been taught self-surrender exercises and deep breath relaxation in lowering blood sugar levels in the elderly Diabetes Mellitus At the Elderly Posyandu, the working area of the Kerinjing Health Center is Kerinjing Village, Ogan Ilir Regency, Palembang. The approach methods used to achieve the Output Target are determined, namely; Education (Counseling), Demonstration of Self-Resignation Training, and Deep Breath Relaxation in Lowering Blood Sugar Levels of Diabetes Mellitus Elderly. The application of the Combination of Self-Resignation Exercises and Deep Breath Relaxation is carried out routinely in the elderly with Diabetes Mellitus there is a decrease in Blood Sugar levels by involving cadres and elderly families who control the implementation of the exercise.

Deep Learning of Diabetic Retinopathy Classification in Fundus Images

Diabetic retinopathy is an eye disease in diabetic patients due to damage to the small blood vessels in the retina due to high and low blood sugar levels. Accurate detection and classification of Diabetic Retinopathy is an important task in computer-aided diagnosis, especially when planning for diabetic retinopathy surgery. Therefore, this study aims to design an automated model based on deep learning, which helps ophthalmologists detect and classify diabetic retinopathy severity through fundus images. In this work, a deep convolutional neural network (CNN) with transfer learning and fine tunes has been proposed by using pre-trained networks known as Residual Network-50 (ResNet-50). The overall framework of the proposed classification model is divided into three major phases, including pre-processing, training the Resnet-50 network, and classification with evaluation. In the first phase, pre-processing techniques are applied to the APTOS2019 fundus images dataset to find the best features and highlight some fine details of these images. The resnet-50 network was trained in the second phase using the training set and saved the best model obtained that gives high accuracy during the training process. Finally, this saved model has been implemented on the testing dataset for classification DR grades. The proposed model shows good and best classification performance, which was obtained with an accuracy of 98.3%, a precision of 98.4%, an F1-Score of 98.5 % and the recall of 98.4%.

Improving elderly life: Foot exercises for blood sugar control and enhanced quality of life

Elderly people are at risk of developing degenerative diseases, one of which is diabetes mellitus. Diabetes management includes education, diet management, physical activity, and pharmacotherapy. This community service aims to determine changes in blood sugar levels after doing leg exercises to improve the quality of life of the elderly. The service participants were 51 cadres and elderly people at the Cempaka Putih Kedung Anyar Elderly Integrated Healthcare Center, Sawahan District, Surabaya City. Community service activities include; checking blood sugar levels, counseling about diabetes mellitus and foot exercise training. The success of community service is assessed based on the activeness of the elderly in doing foot exercises and a comparison of the results of checking blood sugar levels before and after being given foot exercise exercises. Before being given the leg exercise, there were 21 people (41%) whose blood sugar levels were high, and after doing the leg exercise, there was a decrease to 10 people (19.6%) who had high blood sugar levels, and almost all respondents had 80% blood sugar levels. normal. Foot exercises can lower blood sugar levels in the elderly. Regular foot exercises can maintain blood sugar levels in normal conditions. People can apply foot exercises regularly so that blood sugar levels are normal and the quality of life improves.

Effects Of Psidium Guajava Crude Leaf Methanol-Extract On Lowering Blood Sugar Levels In Rat

Blood sugar levels, or blood glucose levels, are crucial for overall health and are regulated by the pancreas through insulin. Normal blood sugar levels range between 70-99 mg/dL when fasting and up to 140 mg/dL two hours after eating. Abnormal blood sugar levels can suggest a variety of health issues, including hypoglycemia (low blood sugar levels caused by excess insulin, certain drugs, or illnesses such as diabetes) and hyperglycemia (high blood sugar levels associated with diabetes). Regular blood sugar monitoring is necessary, especially for diabetics. Guava, a tropical fruit, includes a variety of phytochemicals that have been linked to pharmacological benefits such as antibacterial capabilities. This research uses an extraction process involving solid-liquid extraction or maceration, with methanol being the optimal solvent. The extract yields 9.51%. Wistar rats are used to investigate its antidiabetic efficacy. The rats are divided into three groups: positive control, negative control, and extract treatment. Diabetes is induced by subcutaneous injection of Alloxan, followed by oral administration of the methanol extract. Blood glucose levels are assessed after fasting for 6-8 hours. The extract from dried Guava leaf powder yields a concentrated extract with a 9.51% yield. In vivo assessments showed a significant reduction in blood glucose levels in rats treated with guava leaf extract, suggesting potential anti-hyperglycemic effects. The phenolic compounds in guava leaves contribute to antioxidant and anti-hyperglycemic effects. The study highlights the potential therapeutic effects of guava mint leaves and their extract components for diabetes management and antioxidant health benefits.

Association of accelerometer-measured sedentary time, light intensity physical activity levels with cardiometabolic disease risk in Indian office workers: Insights from the SMART-STEP study

Background and aimsSedentary time (ST) is found to be an independent risk for cardiometabolic disease (CMD). While moderate to vigorous physical activity has demonstrated clear benefits in reducing the risk of CMD, only a fraction of the world's population meets the recommended levels. The benefits of easily attainable light-intensity physical activity (LIPA) on CMD risk factors are seldom explored. Our study aimed to explore the association of accelerometer-measured ST and LIPA with CMD risk among Indian office workers. MethodsST and LIPA were recorded using a hip-worn accelerometer (Actigraph) for seven consecutive days, while CMD risk factors were evaluated in 130 insufficiently active office workers. The association of accelerometer-measured ST and LIPA with CMD risk factors were examined using multivariate regression. ResultsHigher ST were positively associated with high body mass index (β = 0.330, p < 0.001) and body fat percentage (β = 0.422, p < 0.001), while LIPA exhibited an inverse relationship with the above variables. Additionally, higher LIPA was associated to low fasting blood sugar levels (FBS) (β = −0.308, p = 0.023). Similarly, high ST was associated with low heart rate variability (HRV) (β = −0.407, p = 0.024) while high LIPA was associated with high HRV (β = 0.379, p = 0.003). However, the associations remain insignificant for majority of other CMD risk factors. ConclusionElevated ST is consistently linked to higher body mass, FBS and lower HRV (an indicator of autonomic stability). LIPA is associated with lower risk of above variables. Still, the association of ST and LIPA with other CMD risk factors remain uncertain. Longitudinal studies with larger samples of Indian office workers is needed to validate the present study findings.

The Effect of Manggist Skin Juice on The Stability of Blood Sugar Levels in Diabetes Mellitus (DM) Patients

ABSTRACT Blood sugar level refers to the level of glucose in the blood. One that can maintain stable blood sugar levels is mangosteen peel juice, because mangosteen peel juice contains xantones and flavonoids that stabilize blood sugar levels. This study aims to determine the effect of mangosteen peel juice on the stability of blood sugar levels in diabetes mellitus patients at the Public Health Center Sibolangit. The design of this research is Quasi Experiment Design using One-group pretest posttest design. The sample in this study were 10 patients using purposive sampling. Data analysis used Paired Sample T-Test. The results showed that the P-value was 0.027 (P-value &lt;0.05) so it could be concluded that there was an effect of giving mangosteen rind juice on the stability of blood sugar levels in diabetes mellitus patients at the Sibolangit Health Center. Mangosteen peel juice is one of the herbal medicines that can lower blood sugar levels in Diabetes Mellitus patients. Keywords: Juice Mangosteen Skin, The Stability of Blood Sugar Levels

Diabetes Mellitus Patients' Knowledge About Hypoglycemia and Initial Management of Hypoglycemia

Acute complications Diabetes Mellitus such as hypoglycemia is an emergency situation that can occur in the course of Diabetes mellitus disease. Hypoglycemia is a result of lower blood sugar levels below normal. The purpose of this research is to know the description of Diabetes Mellitus patient's knowledge about Hypoglycemia and the initial treatment of Hypoglycemia. The research design used descriptive research design and purposive sampling technique with a sample size of 30 people. Data collection using questionnaire sheet. The results showed that Diabetes Mellitus patients on the initial handling of Hypoglycemia found that 46.7% were in the category of knowledge enough and 16.7% less. Counseling by Polyclinic officers in Diabetes Mellitus patients about early handling Hypoglycemia needs to be done to treat Hypoglycemia.

Diabetes Mellitus Patients' Knowledge About Hypoglycemia and Initial Management of Hypoglycemia

Acute complications Diabetes Mellitus such as hypoglycemia is an emergency situation that can occur in the course of Diabetes mellitus disease. Hypoglycemia is a result of lower blood sugar levels below normal. The purpose of this research is to know the description of Diabetes Mellitus patient's knowledge about Hypoglycemia and the initial treatment of Hypoglycemia. The research design used descriptive research design and purposive sampling technique with a sample size of 30 people. Data collection using questionnaire sheet. The results showed that Diabetes Mellitus patients on the initial handling of Hypoglycemia found that 46.7% were in the category of knowledge enough and 16.7% less. Counseling by Polyclinic officers in Diabetes Mellitus patients about early handling Hypoglycemia needs to be done to treat Hypoglycemia.

Effectiveness of Chickpeas on Blood Sugar: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Diabetes affects one in eleven adults globally, with rising cases in the past 30 years. Type 1 and type 2 cause blood sugar problems, increasing cardiovascular risks. Dietary control, including chickpeas, is suggested but needs more research. Comprehensive searches were conducted across multiple databases for the randomized controlled trial efficacy of chickpea consumption to lower blood sugar levels to a healthy range, with data extraction and risk of bias assessment performed independently by two researchers. Statistical analysis was performed using RevMan 5.4, expressing continuous data as mean differences and risk ratios with 95% confidence intervals, and a summary of the findings is provided considering the variations in study characteristics. A total of 118 articles were initially identified from seven databases, primarily from Anglo-American countries, resulting in 12 selected studies after the identification and screening processes. These studies involved 182 participants, focusing on healthy or normoglycemic adults, and assessed the effects of chickpeas compared to various foods such as wheat, potatoes, pasta, sauce, cheese, rice, and corn. A meta-analysis involving a subset of studies demonstrated that chickpeas were more effective in reducing blood glucose iAUC compared to potatoes and wheat. Chickpeas offer the potential for blood sugar control through low starch digestibility, high fiber, protein, and hormonal effects. Although insulin benefits are seen, statistical significance varies, supporting their role in diabetic diets focusing on nutrient-rich foods over processed carbs.

Millets: A Nutritional Powerhouse With Anti-cancer Potential.

Millets are important food crops widely grown by smallholder farmers in the arid and semi-arid regions of the world. Millets are rich in protein, dietary fiber, micronutrients, and have a low glycemic index (GI)and desirable bioactive compounds. Due to their higher nutritional content, millets are popularly known as "nutricereals".Coinciding with the United Nations and the Food and Agriculture Organization's declaration of 2023 as the "International Year of Millets," this reviewunderscores the nutritional value of these grains from the Poaceae family. The consumption of nutricereals is associated with several health benefits including lowering of blood sugar levels (diabetes), controlling blood pressure, and providing protection against thyroid, cardiovascular, and cancer diseases. A review of the literature from PubMed and Google Scholar was done focusing on the health benefits and anti-cancer properties of different millets.Millets have a rich content of macronutrients like carbohydrates and proteins, as well as micronutrients and bioactive compounds, including dietary fibers, essential fatty acids, and phytochemicals. This article exploresmillets' nutritional elements, i.e., macronutrients, micronutrients, and bioactive compounds, and provides insights into the types of carbohydrates present, the prebiotic function of dietary fibers, and millets' low GI. The study identified the mechanisms by which millets may deter cancer growth, focusing on the roles of dietary fibers, plant protease inhibitors, and bioactive peptides.Additionally, it compared the mineral and vitamin content of millets to other common grains, such as rice and wheat, and explored the potential health advantages of millets over other cereal crops. This review systematically investigatedthe health advantages of millets, particularly, their anti-cancer capabilities. Dietary fibers, plant protease inhibitors, and bioactive peptides present in millets have the capacity to induce apoptosis, inhibit cell proliferation, and interact with gut microbiota leading to potential anti-cancer effects. This review also identifiedexisting challenges in the bioavailability and effective delivery of millets' bioactive peptides, advocating for further research to maximize their health benefits.

A single dietary factor, daily consumption of a fermented beverage, can modulate the gut bacteria and fecal metabolites within the same ethnic community.

Our study investigated how a traditional drink called Apong, made from fermented rice, affects the gut and health of the Mishing community in India. We compared two groups of people who drink Apong to a group of people who do not drink it. To accomplish this, we studied the gut bacteria, fecal metabolites, and blood samples of the participants. It was found that the people who drank Apong had higher blood pressure but lower blood sugar and protein levels than people who did not drink it. We also found that the gut microbiome composition of people who drank Apong was different from those who did not drink it. Moreover, people who drank Apong had lower levels of isovaleric acid in their feces. Overall, this study shows that a traditional drink like Apong can affect the gut bacteria of a community.

Magnetic resonance imaging features to evaluate the neonatal hypoglycemia brain injury and investigation of related risk factors under the fuzzy C‐means clustering intelligent algorithm

AbstractThis research was aimed to analyse the application value of magnetic resonance imaging based on Fuzzy C‐means (FCM) algorithm in neonatal hypoglycemia brain injury (HBI), and explore the risk factors related to the occurrence of brain injury in children, to provide guidance for clinical diagnosis and treatment. 114 children with hypoglycemia were divided into brain injury group (58 cases) and no brain injury group (56 cases) according to whether they had brain injury or not. The MRI image signal performance, general data, average minimum blood glucose value, duration of hypoglycemia, first feeding time, age of onset of hypoglycemia, and algorithm segmentation performance of the two groups of patients were observed and compared. Furthermore, the Logistic factor analysis was carried out to summarize the MRI characteristics and related risk factors of neonatal hypoglycemic brain injury. The results showed that the average minimum blood glucose (1.09 ± 0.53 mmoL/L) in the brain injury group was lower than that in the non‐brain injury group (1.75 ± 0.49 mmoL/L), and the duration of hypoglycemia (43.1 ± 21.07 h) was higher than that in the non‐brain injury group (13.79 ± 6.81 h), p &lt; 0.05. The first feeding time and age of hypoglycemia in the brain injury group were higher than those in the non‐brain injury group, showing a difference with p &lt; 0.05. In the brain injury group, all 58 cases showed high DWI (diffusion weighted imaging) signal at the damaged site at the early stage of MRI (magnetic resonance imaging), and 23 cases (39.66%) were involved in parieto‐occipital lobe. Image segmentation coefficient of Vpc increased significantly under FCM clustering algorithm (p &lt; 0.05). Late first feeding time, low blood sugar level, and long duration were high risk factors for hypoglycemic brain injury. In conclusion, MRI images based on FCM clustering algorithm had higher image quality. Late first feeding time, low blood sugar level, and long duration of hypoglycemia were high risk factors for hypoglycemic brain injury.

Recent Trends in the Application of Oilseed-Derived Protein Hydrolysates as Functional Foods.

Oilseed-derived proteins have emerged as an excellent alternative to animal sources for the production of bioactive peptides. The bioactivities exhibited by peptides derived from plant proteins encompass a wide range of health-promoting and disease-preventing effects. Peptides demonstrate potential capabilities in managing diseases associated with free radicals and regulating blood pressure. They can also exhibit properties that lower blood sugar levels and modify immune responses. In addition to their bioactivities, plant-derived bioactive peptides also possess various functional properties that contribute to their versatility. An illustration of this potential can be the ability of peptides to significantly improve food preservation and reduce lipid content. Consequently, plant-derived bioactive peptides hold great promise as ingredients to develop functional products. This comprehensive review aims to provide an overview of the research progress made in the elucidation of the biological activities and functional properties of oilseed-derived proteins. The ultimate objective is to enhance the understanding of plant-derived bioactive peptides and provide valuable insights for further research and use in the food and medicine industries.