Low Rate Applications Research Articles

Ocimum gratissimum mediated green synthesised iron oxide nanoparticles as a plausible nanofertilizer for peanut plant (Arachis hypogaea)

Exploring the potential of iron/iron oxide nanoparticles (IONPs) to act as fertilizer is an area of immense interest. This paper reports the green synthesis of IONPs using aqueous extract of Ocimum gratissimum leaves and its characterization with XRD, HRTEM and FTIR. This environmentally benign route avoids hazardous and toxic chemicals commonly employed in nanoparticle synthesis. The IONPs formed (Fe2O3) are stabilized by the phenolic and aromatic compounds found in the aqueous extract of Ocimum gratissimum and are of small crystallite size (5–30 nm). Peanut seedlings treated with these IONPs exhibited a superior growth performance at lower application rates (100 mg L−1), as evidenced by better growth parameters, which also corroborated with gibberellic acid accumulation in a dose-dependent manner. The differential activity of green synthesized IONPs, highlighted in this study, compared to already reported chemically synthesized IONPs, reveals their functional superiority.

Is radiotherapy still the optimal initial choice for patients with early-stage low-grade follicular lymphoma in the modern era? A population-based study.

Despite radiotherapy (RT) is recognized as preferred initial therapy for early-stage low-grade follicular lymphoma (FL) by many international practice guidelines, the medical oncologist has improperly underutilized RT, and diverse management strategies, including systemic therapy (ST), combined modality (CM) and watch and wait (WW), are still used. Except survival outcomes, previous studies concerned little about the treatment-related toxicity, which is also important factor in choosing initial management strategy, especially second primary malignancies (SPMs). The aim of this study was to compare the overall survival (OS) and the SPMs risk between different management strategies, which can provide guidance for the choice of optimal initial management strategy. Data was acquired from the Surveillance, Epidemiology, and End Results (SEER) database. Finally, A total 10,900 patients were identified, in which 930 cases developed SPMs. The use of radiotherapy (RT) has remained consistently low, with a utilization rate of around 20%, while most patients have received watchful waiting (WW) and systemic therapy (ST). In the rituximab era, multivariate analysis indicated that RT exhibited significantly superior OS and did not increase SPMs risk in comparison with ST and WW. At the same time, although there were no significant differences in OS between CM and RT, RT had significantly lower SPMs risk in comparison with CM. The use of RT improved the OS and did not increase the SPMs risk in comparison with other management strategies. Considering the low application rate of RT, oncologists should emphasize and increase the use of RT as an initial management strategy in patients with early-stage low-grade FL.

Phosphate Fertilizers’ Dual Role in Cadmium-Polluted Acidic Agricultural Soils: Dosage Dependency and Passivation Potential

Cadmium (Cd) contamination in agricultural soils is a common issue, posing health risks as it enters the human body through the food chain. Commonly used phosphate fertilizers (PFs) not only provide essential phosphorus (P) nutrients to crops but also serve as P-containing materials for immobilizing heavy metals (HMs) like Cd in soils. Therefore, understanding the passivation effects of PFs on soil Cd and their potential influencing factors is crucial for mitigating soil Cd pollution. In this study, the impact of multi-crop applications (75 mg P kg−1, 150 mg P kg−1) of four kinds of PFs on reducing soil Cd toxicity and decreasing Cd accumulation in spinach was investigated. The results indicated that under the low application rate (75.0 mg P kg−1), all PFs could passivate Cd, and CMP demonstrated the most effective passivation of Cd. However, under the high application rate (150 mg P kg−1), the immobilization effect diminished or even activated Cd. Among the different types of PFs, CMP application alleviated soil acidification and significantly reduced soil-available Cd, showing the best performance in promoting spinach growth and Cd inhibition. These results suggest that PF application in Cd-contaminated soils affects spinach growth and Cd accumulation, with soil pH, available phosphorus (AP), and Cd dynamics being crucial; moreover, low-P, micronutrient-rich, alkaline PFs like CMP optimize spinach yields and minimize Cd uptake, and excessive application of soluble PFs decreases pH, increases Cd mobility, and poses health risks, suggesting a need for balanced fertilizer use.

The novel herbicide icafolin‐methyl is a plant‐specific inhibitor of tubulin polymerization

AbstractBACKGROUNDWithout controlling weeds, it is estimated that about one third of global crop yields would be lost. Herbicides remain the most effective solution for weed control, but they face multiple challenges, such as the emergence and growth of resistant weed populations. Consequently, there is an urgent need for either herbicides with new modes of action or at least novel chemistries within established modes of action, with outstanding efficacy but without showing cross‐resistance to the herbicides present in the prospective markets.RESULTSIcafolin‐methyl is a novel herbicide with a unique biological profile. It is hydrolyzed in planta to the carboxylic acid icafolin. After post‐emergence application icafolin‐methyl and icafolin both show high efficacy against the most relevant competitive weeds in cold and warm season cropping systems at low application rates, including resistant black‐grass and rye‐grass biotypes. Biochemical and genetic evidence is provided that icafolin‐methyl and icafolin inhibit plant tubulin polymerization probably by binding to ß‐tubulins.CONCLUSIONIcafolin‐methyl is a novel non‐selective herbicide with an established mode of action, but with a superior potency and spectrum, specifically after foliar application. This makes icafolin‐methyl fundamentally different from existing tubulin polymerization inhibiting herbicides. It complements the farmers weed control toolbox, particularly with respect to resistance management. © 2024 Society of Chemical Industry.

Fertility and tillage intensity affect weed community diversity and functional structure in long-term organic systems.

Knowledge of how agricultural management interacts with weed seed banks and emergent weed communities is crucial for proactive weed management. Though studies have detailed how differences in disturbance and nutrient applications between organic and conventional herbicide-based systems affect weed communities, few have focused on these same factors in contrasting organic systems. This study assessed the seed banks and emergent weed communities from the most recent crop rotation cycle (2017-2022) of a long-term experiment, which compared four organic grain and forage cropping systems differing in nutrient inputs and soil disturbance. The high fertility (HF) system received high-rate nutrient applications, low fertility (LF) received low-rate applications, enhanced weed management (EWM) focused on weed control through frequent soil disturbance, and reduced tillage (RT) prioritized soil health with less intense or frequent soil disturbance. Soil samples for greenhouse germination assays were collected at the beginning (2017) and end (2022) of the rotation to explore how these four systems influenced seed bank dynamics over time. Weed community biomass was also sampled in each crop during this time. Treatment effects on weed abundance, taxonomic diversity, and community-weighted means and functional dispersion of weed traits were analyzed with generalized mixed-effect models. The RT system had the highest weed seed bank taxonomic diversity, and EWM had the lowest. RT and LF had higher functional dispersion of traits than HF in the seed bank. Weed seed bank communities in HF and RT were characterized by short, small-seeded, and early germinating weed species. However, seed banks were also labile: Differences between systems in seed density and all other mean trait values were dependent on the crop, which preceded seed bank sampling. Likewise, differences among emergent weed communities in the four systems depended on an interaction between crop species and their planting year. Results suggest that resource availability and intensity of disturbance act as weed community assembly filters in organic cropping systems. Organic growers seeking to design systems that balance weed management and production goals can use relatively low soil disturbance and nutrient application to increase weed community taxonomic or functional diversity without necessarily increasing weed biomass or seed bank density.

Precision management influences productivity and nutrients availability in dryland cropping system

AbstractPrecision management (PM) aims to reduce inputs while increasing land productivity and economical return and enhancing cropping system resiliency to climate change. This study evaluated how climate (precipitation) and management influenced yields and soil nutrients in a dryland agricultural system. We compared an “aspirational” (ASP) system (no‐till, 4‐year rotation of winter wheat [Triticum aestivum L.], corn [Zea mays L.], proso millet [Panicum miliaceum L.], and fallow/flex) to a traditional “business‐as‐usual” (BAU) system (reduced tillage, 2‐year rotation of winter wheat and fallow: W–F). Phases of each rotation were included yearly throughout the study period (2018–2022) with three replications. The ASP system incorporated PM by dividing each ASP field into three zones (high‐, medium‐, and low‐PM) according to prior yield and topography. Nitrogen was applied at high, medium, or low application rates within those zones. Under favorable precipitation, wheat, corn, and millet yields responded to PM treatments, with yields increasing proportional to N addition. Years with low in‐season precipitation had a significant reduction in wheat and corn yields (2020 and 2022) and complete millet yield failures (2020 and 2021). Low soil organic matter accumulation (0.1%–0.5%) and a reduction in soil macro‐ and micronutrient status suggested that soil nutrient additions are needed to prevent soil‐nutrient degradation. The ASP treatment added a third crop every 4 years and did so without significantly decreasing wheat yield following fallow. The ASP management shows promise as an alternative to BAU in the Great Plains dryland production region.

Foliar applications of phenylalanine and prohexadione calcium for managing tannin content in cold-hardy hybrid grape cultivars

Cold-hardy hybrid grape cultivars have low tannin content compared to Vitis vinifera cultivars, which leads to unbalanced red wines and therefore low-quality wines. Viticultural practices, such as nitrogen fertilisation and the use of plant growth regulators, have shown to be effective interventions to modify tannin content in V. vinifera cultivars and may be effective with cold-hardy hybrids. Foliar applications of phenylalanine (Phe, 100 mg/L) and prohexadione calcium (ProCa, 50 mg/L) were applied separately and in combination (ProCa+Phe) to Marquette grapevines grown in Iowa, USA in 2022 and 2023. Treatments were assigned following a split-plot design. Berry weight, diameter, seeds per berry, tannin content, and iron-reactive phenolics content of skins and seeds were analysed at five phenological time points. Samples from treated vines were compared to untreated control samples using a random-intercepts linear regression model. Overall, the effect of year was more impactful than the individual effects of treatments due to differences in temperature and rainfall during berry development. However, skin and seed tannin and IRP were significantly affected by the Year2023:ProCa interaction at 3 weeks post fruit set and véraison, respectively, suggesting ProCa treatment may be more effective with multiple applications in consecutive years. Low application rate may be a reason for limited treatment effectiveness and further work on dose response may demonstrate foliar sprays of Phe and ProCa to be effective tools at managing phenolics content in Marquette grapes.

Exploration of Network Management Methods in Higher Vocational Computer Education

With the rapid development of information technology, higher vocational computer education is gradually turning to network management to meet the needs of the information age. This paper describes the importance of network management in higher vocational computer education. The analysis of the status quo of network management reveals the problems of lagging in management mode, the low application rate of computer networks, and the constraints of traditional teaching. In response to these problems, suggestions and discussions are put forward, including strengthening the construction of network infrastructure, improving the network management mechanism, etc., to promote education management towards a more advanced and flexible network direction.

A 10-year evaluation of management practices and nutrient losses from dairy farms in New Zealand – Trends and drivers

Good management practices (GMPs) on dairy farms have been shown to reduce contaminant losses and improve water quality. Few national long-term datasets exist globally on management practices on dairy farms over time and their effect on nutrient losses. Here, we examine 50 parameters across a 10-year period (from 2013 to 2022) thought to influence estimates of nitrogen (N) and phosphorus (P) losses (kg ha−1 yr−1) to water from dairy-farmed land in New Zealand. The number of farms in our database increased from 137 in 2013 to a total of 378 in 2022. The years from 2013 to 2017 were classed as ‘period 1’ and from 2018 to 2022 as ‘period 2’, which aligned with more intensive extension of GMPs. Nationally, there was a small increase in median N and P loss rates (38 – 40 kg N ha−1 yr−1 and 1.1 – 1.2 P kg ha−1 yr−1), fertiliser applied 140 – 141 kg N ha−1 yr−1 and total milk solids produced by 11 % between periods. However, between 1 – 42 % of farms exhibited decreasing N loss trends regionally, which were related to (in order of decreasing importance): N fertiliser applied, irrigation type, and forage establishment (cultivation) practice. Similarly, 1 – 25 % of farms with decreasing P trends regionally, trends were related to soil order, P fertiliser applied, and effluent storage method. We also found that these farms showed increased adoption of effluent and forage establishment method GMPs between periods, for example, the use of low-rate effluent application, direct drill, and minimum tillage, and increased effluent storage practice. These data suggest good management practices shown to decrease N and P losses from dairy-farmed land to water in New Zealand are being adopted; however, continued uptake on all farms will be required to achieve further improvement.

Utilizing biochars to stabilize mercury in contaminated floodplain sediment: Implications on mercury remediation.

Major weather events contribute to the mobility and remobilization of legacy mercury (Hg) contamination and sequestration within sediments. Remediation using biochar as a soil amendment is a useful technique to immobilize and decrease Hg toxicity. This study explored whether biochar application is effective at stabilizing labile mercury (LaHg) from floodplain sediment. Controlled mesocosms simulating contamination events and flooding conditions were conducted. Floodplain sediment, which experiences annual periodic flooding, was collected. Sediment was spiked with inorganic Hg, applied with different types of biochar, and experienced simulated flooding events. Four types of biochar, pure rice husk (RH), pure peanut hull (PH), sulfur-modified rice husk (SMRH), and sulfur-modified peanut hull (SMPH), were applied at 10 and 40g/kg rates (i.e., RH 10, RH 40; PH 10, PH 40, SMRH 10, SMRH 40, SMPH 10, SMPH 40). Total Hg, methylmercury, and LaHg concentrations were analyzed by coupling with redox potential measurements. Results indicate that SMRH 10, PH 10, PH 40, SMPH 10, and SMPH 40 successfully remediate Hg by stabilizing and reducing LaHg species from floodplain sediment. However, a high Hg methylation potential was observed with unsulfated and sulfated peanut hulls (PH 10, PH 40, SMPH 10, and SMPH 40), as they tend to create a reducing microenvironment that favors sulfate reduction reactions. Additionally, sulfur-modified biochar tends to promote Hg methylation potential at high application rates (i.e., 40g/kg). We thus recommend using SMRH at a relatively low application rate (SMRH 10) for the remediation of Hg from floodplain sediment.

Gender Differences in Defibrillator Practices in Out-of-Hospital Cardiac Arrest

Objectives Disparities remain in survival after out-of-hospital cardiac arrest (OHCA) for women compared to men. Our objective was to evaluate differences in automated external defibrillator (AED) use before Emergency Medical Services (EMS) arrival and time from arrival to initial EMS defibrillation by EMS-assessed gender (women or men). Methods This was a secondary analysis of adult non-traumatic, EMS-treated OHCA cases in the Portland Cardiac Arrest Epidemiologic Registry from 2018 to 2021. Emergency Medical Services-witnessed cardiac arrests were excluded and the primary outcomes were pre-EMS AED application and the time from EMS arrival to first defibrillation among patients in a shockable rhythm at first rhythm assessment without pre-EMS AED application. We examined pre-EMS AED application rates overall and separately for law enforcement, in cases where they were on-scene before EMS without a lay bystander AED applied, and lay responders, in cases where law enforcement had not applied an AED. We used multivariable logistic and linear regressions to adjust for potential confounders, including age, arrest location, witness status, bystander CPR, year, and time from dispatch to EMS arrival. We accounted for clustering by county of arrest using a mixed-effects approach. Results Of the 3,135 adult, EMS-treated non-traumatic OHCAs that were not witnessed by EMS, 3,049 had all variables for analysis, of which 1,011 (33.2%) were women. The adjusted odds (adjusted odds ratio [95% CI]) for any pre-EMS placement of an AED was significantly higher for men compared to women (1.40 [1.05–1.86]). These odds favoring men remained when examining law enforcement AED application (1.89 [1.16–3.07]), but not lay bystander AED application (1.19 [0.83–1.71]). Among patients still in arrest on EMS arrival, with a shockable initial EMS rhythm, and without pre-EMS AED application, the time from EMS arrival on-scene to initial defibrillation was significantly longer for women compared to men (+0.81 min [0.22–1.41 min]). Conclusions Women with OHCA received lower rates of pre-EMS AED application and delays in initial EMS defibrillation compared to men.

Phosphorus High-rate application through band placement improved cotton productivity under arid climate

The plant-available soil phosphorus rate and methods for applying phosphatic fertilizer and soil P-fixation capacity are critical factors for lower cotton productivity in Southern Punjab, Pakistan. Hence, a two-year study was conducted in Central Cotton Research Institute (CCRI), Multan, Pakistan, to examine the effects of various P rates and application methods on cotton crop output during the growing seasons of 2014 and 2015. Phosphorus was applied in four rates (0, 40, 80, and 120 kg ha−1 P2O5) using broadcast, band application, and fertigation methods. Results indicated that the impact of P rates was statistically significant on plant height, the number of nodes, monopodial and sympodial branches, leaf area index, harvest index, and seed cotton yield. The greater P application (120 kg P2O5 ha−1) had a better effect on cotton productivity than the lower application rates (0, 40, and 80 kg P2O5 ha−1). The band application responded better on nodes plant−1, sympodial branches plant−1, boll weight, leaf area index, lint yield, and harvest during the growing season 2015. Therefore, by adopting the band application coupled with 120 kg P2O5 ha−1 rather than the conventional method of broadcast, productivity of cotton crops could be increased.

Effects of Biochar Pyrolysis Temperature and Application Rate on Saline Soil Quality and Maize Yield

The application of biochar to improve the quality of saline soils has attracted widespread attention. However, the impact of saline soil amendments with biochar prepared at different pyrolysis temperatures remains unclear. Therefore, we conducted a two-year (2022–2023) field experiment in the Hetao Irrigation District, China, to evaluate the effects of the biochar pyrolysis temperature (C1: 300 °C, C2: 500 °C, and C3: 700 °C) and application rate (T1: 10 t/ha and T2: 20 t/ha) on the soil quality and maize yield. The results indicated that (1) all biochar treatments significantly decreased the soil bulk density and increased the soil porosity; (2) treatment C3T1 significantly increased the soil moisture content and decreased soil salinity. The C3T2 treatment significantly increased the soil’s organic carbon content, and the soil’s available phosphorus content was greatest in the C1T2 treatment. (3) The maize yield increased linearly with the soil quality index (SQI), which was attributed mainly to improvements in the soil water–salt conditions and increases in the soil organic carbon content. In summary, biochar produced at high pyrolysis temperatures, when applied at a low application rate (C3T1), can result in high corn yields and improve saline soil quality.

Extraction of crop canopy features and decision-making for variable spraying based on unmanned aerial vehicle LiDAR data

Implementation of precision agriculture aerial applications using unmanned aerial vehicles (UAVs) represents a pivotal technological aspect in precision agriculture. However, current UAV applications are still far from realizing true precision variable spraying. The use of UAVs to analyze and model crop growth, pest and disease conditions, and other pertinent information to enable targeted precision spraying poses a formidable challenge. Herein, a UAV variable-rate spray system with adaptive flow control based on crop canopy morphology was developed using a UAV equipped with a light detection and ranging (LiDAR) sensor to support precision spraying of cotton. Point cloud data captured by the LiDAR sensor initially undergo processing using the simple morphological filter (SMRF) algorithm and feature extraction function. Subsequently, cotton canopy volumes measured by the alpha shape algorithm, convex hull by slices shape algorithm, and voxel-based method were compared with manual measurements with coefficient of determination R2 values of 0.89, 0.78, and 0.82, respectively. The results of the validation experiments denote that the cotton canopy volume obtained using the alpha shape algorithm is in good agreement with that obtained using manual measurements; thus, this algorithm is employed for volume calculations in this design. Models were constructed to relate UAV flight parameters, cotton canopy volume, and spraying parameters to the duty cycle of variable control signals, which enabled the UAV to adjust the flow rate in real time to match the cotton canopy structure. In addition, a polygonal prescription map decoding algorithm based on the cotton canopy morphology was introduced. This algorithm is used for real-time decoding of prescription maps and extraction of flow, latitude, and longitude information. Finally, field experiments were conducted, and the results indicate that the UAV variable-rate spray system designed in this study exhibits biological efficacy (effective application thresholds provided by the pesticide manufacturer) comparable to that of the constant-rate spray system at a lower application rate. Furthermore, it exhibited superior spray deposition efficiency and coverage compared with the constant-rate spray system. Notably, the use of the variable-rate spray system in cotton crops resulted in a 43.37% reduction in spray volume while maintaining high application quality, providing an opportunity for pesticide and labor cost savings.

Nontarget effects of herbicides on annual forbs and seeded grass in the Great Basin, United States, are partially offset by planting depth and application rate

Pre‐emergent herbicides can reduce the abundance of invasive annual plants, but they can also harm native plants, particularly annuals or perennial seedlings, including seeds planted during restoration. We assessed the effects of imazapic and indaziflam on invasive target and nontarget native plants in the Great Basin, a region with extensive invasive annual grasses. We tested nontarget effects on native annual forbs in an agricultural field previously used to grow native annual forbs, which contained a large seed bank. We seeded perennial grass (Elymus elymoides) at multiple depths to determine susceptibility and resistance. Herbicides were applied at full and reduced rates to mimic the effect of litter in natural systems. We observed reductions in most non‐native species in all treatments, but also extensive reductions of native annual forbs, although these were offset at lower application rates, and some species (e.g. Amsinckia tessellata and Microsteris gracilis) were less susceptible than others. Herbicides, particularly indaziflam, reduced E. elymoides emergence, but planting seeds at 2–3 cm depths improved emergence, particularly for imazapic, with 15–68% greater emergence than seeds planted at 1 cm. We suggest surveys for native annual forbs and resistant invaders before applying herbicides and field testing to determine whether reduced rates could provide weed control while maintaining annual forbs. We suggest planting E. elymoides at 2–3 cm when applying herbicides, an approach that may be effective for other species. Herbicide use can be an effective tool, but our results indicate that mitigation of nontarget effects will be needed to maintain native plant diversity.

Influence of soil organic matter, fertiliser formulation and season on fertiliser nitrogen use efficiency in temperate pastures

Intensively grazed dairy systems use high inputs of fertiliser nitrogen (N), and often supplementary irrigation, to ensure adequate pasture production to support milk output and meet the growing food demand. However, the efficiency of N use in these systems can be low and potential environmental impacts high. This study aimed to test the hypothesis that (1) use of two inhibitors, the urease inhibitor N-(n-butyl) thiophosphorictriamide (NBTPT) and the nitrification inhibitor 3,4-Dimethylpyrazole phosphate (DMPP) reduced N loss and improved pasture production compared to conventional N fertiliser (urea) in irrigated temperate perennial ryegrass (Lolium perenne L.) dairy pasture, and (2) their efficiency was affected by soil and environmental parameters. The effect of repeated applications of urea, at different rates, and the inhibitors were studied on pasture production and agronomic apparent fertiliser N use efficiency (NUE) over 2.5 years. The fate of a single application of N was determined through recovery of 15N-labeled fertiliser applied at 20 and 40 kg N ha−1 was studied in the field for one year. The highest yield and NUE occurred in spring–summer (from August to February) reflecting optimal growing conditions. The highest NUE occurred at low rates of urea application (20 and 40 kg N ha−1). Mineralisation played a key role in supplying N to pasture with 64–82% of total plant N derived from soil organic matter (SOM). Less than 50% of the applied N was recovered in the pasture (37–43%) with a large component retained in the soil (26–43% after one year, 0–40 cm), and slowly released in small amounts (< 2%) to the pasture over time, highlighting the abundant capacity of the native soil N pool to supply pasture N. Loss of N fertiliser (14–31%) was attributed to primarily ammonia (NH3) volatilisation and nitrate (NO3−) leaching. Use of the inhibitors NBTPT and DMPP did not significantly affect pasture yield or NUE, most likely because fertiliser N saved with the inhibitors only played a minor role in plant nutrition with the majority of the plant nutrition provided by the soil organic matter pool.

The influence of different application patterns of propofol on the sedation courses during drug-induced sleep endoscopy.

The course of sedation during drug-induced sleep endoscopy (DISE) depends on the application pattern of the sedative drug. The depth of sedation should imitate light and deep sleep as well. Moreover, there should be as many breathing cycles as possible available for observation during light and deep sedation. The aim of the study was to evaluate different rates of propofol application with respect to the achieved depth and length of the course of sedation. Sixty-three consecutive patients with obstructive sleep apnea and/or snoring undergoing DISE were randomly sedated by propofol perfusion at seven different application patterns: 14, 16, 18, 19, 20, 22 mg/kg/h (0.233, 0.267, 0.3, 0.317, 0.333, 0.367 mg/kg/min) per perfusor and individual bolus application 10 mg each. Sedation depth was monitored by BiSpectral Index™ (BIS). The influence of baseline parameters and the courses of sedation were analyzed. The application rate was the only factor that influenced the depth of sedation. Basic parameters (gender, age, body mass index, apnea-hypopnea index) had no influence on the depth of sedation. The sedation depth was dependent on the rate of propofol application. Regimes at 14 and 16 mg/kg/h as well as bolus application did not reach BIS levels below 50 representing deep sleep. Propofol doses of more than 20 mg/kg/h led to rapid decreases of sedation levels below deep sleep niveau. Propofol rates between 18 and 20 mg/kg/h enable BIS levels below 50 representing deep sleep and providing enough breathing cycles for observation. Lower application rates of propofol provide slower courses of sedation and shallower depths of sedation. A rate of 14 mg/kg/h might be appropriate to reach a sedation plateau at light sleep. A rate of 18 mg/kg/h leads to a sedation, corresponding to deep sleep. The combination of both rates might be a suitable pattern for performing sedation-controlled DISE. 2: Randomized trial.

Efficacy of DAP coated with bacterial strains and their metabolites for soil phosphorus availability and maize growth

Phosphorus (P) use efficiency in alkaline/calcareous soils is only 20% due to precipitation of P2O5 with calcium and magnesium. However, coating Diammonium Phosphate (DAP) with phosphorus solubilizing bacteria (PSB) is more appropriate to increase fertilizer use efficiency. Therefore, with the aim to use inorganic fertilizers more effectively present study was conducted to investigate comparative effect of coated DAP with PSB strains Bacillus subtilis ZE15 (MN003400), Bacillus subtilis ZR3 (MN007185), Bacillus megaterium ZE32 (MN003401) and Bacillus megaterium ZR19 (MN007186) and their extracted metabolites with uncoated DAP under axenic conditions. Gene sequencing was done against various sources of phosphorus to analyze genes responsible for phosphatase activity. Alkaline phosphatase (ALP) gene amplicon of 380bp from all tested strains was showed in 1% w/v gel. Release pattern of P was also improved with coated fertilizer. The results showed that coated phosphatic fertilizer enhanced shoot dry weight by 43 and 46% under bacterial and metabolites coating respectively. Shoot and root length up to 44 and 42% with metabolites coated DAP and 41% with bacterial coated DAP. Physiological attributes also showed significant improvement with coated DAP over conventional. The results supported the application of coated DAP as a useful medium to raise crop yield even at lower application rates i.e., 50 and 75% DAP than non-coated 100% DAP application which advocated this coating technique a promising approach for advancing circular economy and sustainable development in modern agriculture.

Rock Phosphate and Biochar Effects on Greenhouse Gas Emissions and Soil Fertility in Southern Alberta Potato Field

The application of biochar soil amendment and rock phosphate fertilizer to the soil could lead to achieving net zero emissions and food security; however, the effectiveness of using biochar and rock phosphate in southern Alberta brown chernozemic soil is not yet assessed. In the first trial of this study, varying levels of urea (N), with varying levels of biochar (B) were applied. The same level of rock phosphate (RP) and triple super phosphate (TSP) were applied to compare efficiency of the two fertilizers. The second trial involved applying the same nutrients, but with higher levels than the first trial. The results indicated that the fertilizer application rates did not affect the growth and yield of potatoes because of the application rates of the fertilizer and fertility status of the soil, whereas in the second trial, TSP and RP treatments had the same growth and yield. Furthermore, the high application rate of nitrogen fertilizer and RP with or without biochar in the potato plot emitted high nitrous oxide gas emissions while the low application rate of nitrogen fertilizer and RP kept the carbon dioxide in the soil. Nevertheless, in the second experiment, the application of biochar and rock phosphate reduced nitrous oxide and carbon dioxide emissions. We observed high residual nitrogen and manganese nutrients after harvest in the plot treated to rock phosphate and biochar. Therefore, rock phosphate and biochar have the potential to increase food production and mitigate climate change.

Knowledge, Attitudes, and Behaviors of Medical Residents towards Traditional and Complementary Medicine: A Cross-sectional Study

Objective: This study aimed to evaluate the knowledge, attitudes, and behaviors of medical residents working at a faculty of medicine hospital about Traditional and Complementary Medicine (TCM). Material-Method: This is a cross-sectional study. The study was conducted with clinical science assistants working at the faculty of medicine between 15 July and 15 December 2021. A survey containing questions to determine the clinical and demographic characteristics of the participants and their knowledge, behavior, and attitudes toward TCM applications was applied to the participants. Results: A total of 261 medical residents participated. The average age was 29.4±2.6 years and 51.7% (n=135) were male. 82% of the participants were studying internal medicine sciences. The average length of time as a physician was found to be 4.4 years, and the average length of time as a physician in the total branch was 2.6 years. Cupping therapy was the most known method with 55.6%. The most frequently used method (19.2%) was phytotherapy; the most frequently recommended (16.5%) was phytotherapy; the most formally trained (4.2%), was cupping therapy; the most desired formal training (41%) was acupuncture; the most frequently declared method (11.9%) as another TCM method was diet. 36.4% of the participants found TCM useful. 82% thought that these methods should only be applied by trained physicians. Conclusion: It was determined that the level of TCM knowledge among assistant physicians was low. Although the majority of participants had a positive attitude towards TCM, they had low rates of application, implementation, and recommendation.