Lower Energy Intake Research Articles

A better diet quality based on the Healthy Eating Index-2020 is associated with lower energy intake and age but not with a pre-diabetes/T2DM diagnosis among Hispanic women with overweight/obesity.

Low diet quality is related to obesity and type 2 diabetes mellitus (T2DM) risk among Hispanic women. This cross-sectional study compared diet quality among Hispanic women with overweight/obesity based on their T2DM diagnosis (pre-diabetes/T2DM group, n = 104 vs no diagnosis, at-risk group, n = 84). It was hypothesized that having a pre-diabetes or T2DM diagnosis would be associated with better diet quality based on the Healthy Eating Index (HEI)-2020 score. Means were compared using a 2-sample t-test for parametric and Kruskal-Wallis for non-parametric variables. Women with pre-diabetes/T2DM reported a lower intake of total energy (1378 ± 557 vs 1644 ± 703 kcal; P = .004) and cholesterol (228 ± 140 vs 299 ± 216 mg; P = .007). Total HEI score was higher for pre-diabetes/T2DM than the at-risk group (64 ± 8 vs 62 ± 9; P = .027). Among all participants, adequacy subscores were excellent for whole fruits, greens & beans, total proteins, and seafood and plant proteins, good for total fruits (77%); fair for total vegetables and fatty acids (64% for both); and poor for whole grains, and dairy (20% and 53%, respectively). Moderation subscores were very good for added sugars (89%), good for saturated fats (78%), and poor for refined grains, and sodium (44% and 33%, respectively). Compared to the at-risk group, women with pre-diabetes/T2DM had higher fatty acid ratio scores (7 ± 2 vs 6 ± 3, P = .039). Multiple linear regression revealed that pre-diabetes/T2DM did not significantly impact diet quality, but energy intake and age did. Overall, HEI subscores underscore the need to improve diet quality through key food groups in Hispanic women with overweight/obesity, regardless of T2DM status.

Physical Activity and Eating Habits Are Related to Chronic Disease in the Basic Livelihood Security Program

Objectives: Chronic diseases are a significant public health issue, especially for socioeconomically vulnerable population groups. The purpose of this study is to compare the prevalence of chronic diseases in people receiving and not receiving BLS and to determine the prevalence of chronic diseases according to the physical activity and dietary habits of people receiving BLS. Methods: Data were derived from the sixth to ninth waves (2014–2022) of the Korea National Health and Nutrition Examination Survey (KNHANES), focusing on 15,041 participants aged 65 and older. Demographic characteristics, dietary intake, physical activity, and chronic disease status were assessed. Multivariate logistic regression analysis was used to calculate odds ratios for chronic diseases according to physical activity and dietary habits. Results: The BLS group exhibited higher prevalence rates of hypertension and diabetes, along with lower dietary intake of energy, protein, fat, carbohydrates, dietary fiber, and vitamin C, compared to the non-BLS group. A below-average intake of energy and carbohydrates was associated with increased odds of hypertension and diabetes, particularly in the BLS group. For dietary fiber, a significant association with diabetes was found only in the BLS group. Sedentary behavior exceeding 9 h per day was linked to higher odds of chronic diseases in both groups, with stronger associations in the BLS group. Limited walking frequency (less than 1 day per week) further exacerbated risks. Conclusions: BLS recipients demonstrated higher chronic disease prevalence, poorer dietary habits, and more sedentary behavior compared to non-recipients. The associations between lifestyle factors and chronic diseases were generally more substantial in the BLS group, suggesting the need for targeted interventions to improve dietary quality and physical activity patterns in this vulnerable population.

Associations Between Carbohydrate Intake Behaviours and Glycaemia in Gestational Diabetes: A Prospective Observational Study

Carbohydrate intake (CI) has the largest impact on the short-term glycaemia of all nutrients, yet optimal CI management in gestational diabetes remains unclear. Objective: To examine CI behaviours in individuals with recently diagnosed gestational diabetes and their association with self-monitored blood glucose. Methods: Data from 97 individuals were collected using food and blood glucose diaries. CI (including amounts, types, and timing) was manually assessed using 15 g servings over 5–8 days, while a 3-day computerised analysis examined a broader intake of macro- and micronutrients. Results: Elevated fasting glycaemia (EFG) was associated with lower total CI (Mdn 10.8 vs. 12.5 servings/day, p = 0.006), missed meals (Mdn 1.4 vs. 0.0/week, p = 0.007), missed snacks (Mdn 10.5 vs. 7.5/week, p = 0.038), low-carbohydrate meals (<30 g; Mdn 4.3 vs. 2.0/week, p = 0.004), and a higher proportion of energy intake from fat (Mdn 35% vs. 33%, p = 0.047), as compared with in-target fasting glycaemia. In contrast, elevated postprandial glycaemia (EPG) was not significantly associated with total CI, low-carbohydrate meals (<30 g), low-carbohydrate snacks (<15 g), or high-carbohydrate loads (>50 g). EPG was instead associated with high-glycaemic index meals (Mdn 1.6 vs. 0.9 lunch meals/week, p = 0.026; Mdn 0.9 vs. 0.0 dinner meals/week, p = 0.023); and a lower intake of energy (Mdn 7650 kJ vs. 9070 kJ/day, p = 0.031), protein (Mdn 91 g vs. 109 g/day, p = 0.015), fat (Mdn 61 g vs. 84 g/day, p = 0.003), and multiple micronutrients (p <0.05), as compared with in-target postprandial glycaemia. Conclusions: CI profiles differed for individuals with EFG, as compared with EPG, emphasising the need for dietary guidelines tailored for gestational diabetes subtypes. Further interventional studies are needed to explore these findings, particularly the associations between EFG and low CI behaviours.

P0324 Lower Bone Mineral Density and alterations in bone biomarkers DKK-1, Sclerostin, and Periostin in individuals with Inflammatory Bowel Disease

Abstract Background Inflammatory Bowel Disease (IBD) affects the gastrointestinal tract but often presents with extraintestinal manifestations in many patients, including the decline in bone mass. The pathogenesis of IBD is primarily attributed to disturbances in immune responses within the gastrointestinal mucosa and potential disruptions in gut microbiomes. The inflammation of gastrointestinal tract triggers various systems, including the Wnt pathway, which is associated with bone loss. This study explores the alterations in Bone Mineral Density (BMD) and the levels of dickkopf-1(DKK-1), sclerostin (SOST), periostin (POSTN) and bone metabolism markers in IBD patients. Methods We evaluated a cohort of 89 individuals diagnosed with IBD (64% male, 65% with Crohn’s disease, and 35% with ulcerative colitis) with a median (interquartile range) age of 39(28, 54) years and 73 controls of 42(29, 54) years. Bone Mineral Density (BMD) was evaluated using dual-energy x-ray absorptiometry (DXA). We also measured DKK-1, SOST, POSTN, biochemical parameters and bone metabolism markers in the plasma and serum of participants. Results Femoral neck BMD Z-score was lower -0.7(-1.65, 0.2) vs -0.3(-1.1, 0.2) SD, p=0.04, while there was a trend for lower lumbar spine BMD Z-score in patients. Increased C-terminal telopeptides (CTX) 0.49(0.28, 0.68) vs 0.34(0.24, 0.47) pg/mL, p<0.001 and N-terminal telopeptides (NTX) levels 17(13, 23) vs 13.5(11, 18) nMBCE, p<0.001 were observed in patient group, while procollagen-1 N-propeptide and osteocalcin levels had comparable levels. Phosphorus and 25(OH)D levels were comparable between groups, while calcium levels were higher in patients 9.4(9, 9.7) vs 8.9(8.7, 9.2) mg/dl, p=0.02. Parathyroid hormone (PTH) 42(33, 54) vs 51(37, 63) pg/mL, p=0.009 as well as magnesium levels 2(1.8, 2.1) vs 2.1 (2, 2.2), p=0.02 were lower in the patient group. IBD patients exhibited elevated DKK1 levels 2359 (2104, 2583) vs 1580(1419, 1733) pg/mL, p<0.001 and reduced sclerostin 375(313, 501) vs 724(570, 899) pg/mL, p<0.001 and periostin levels 150(108, 204) vs 217(181, 312) ng/mL, p<0.001. DKK1 levels were positively correlated with CTX rho=0.27, p<0.001 and NTX rho=0.26, p<0.001 and negatively correlated with lumbar BMD Z-score rho=-0.21, p=0.02. Conclusion IBD patients were found with an osteopenic phenotype, which can be the consequence of bone loss due to osteoblast activation and increased bone resorption as indicated by increased CTX and NTX levels and osteoblast and osteocyte suppression as indicated by higher DKK-1 and lower periostin and sclerostin levels. The inflammation itself, malabsorption of nutrients, medications (e.g. corticosteroids), and low energy intake could contribute to those pathophysiological changes.

Associations of malnutrition factors with dysphagia mediated by ADL among nursing home residents.

The potential link between malnutrition and dysphagia along with its underlying mechanisms remains unknown. This study aimed to investigate the association between malnutrition factors and dysphagia mediated by adecline in activities of daily living (ADL) among nursing home residents. This cross-sectional study used data from 705 nursing home residents. The primary factors were risk of malnutrition and dysphagia. Abody mass index (BMI) of < 18.5 and insufficient energy and protein intakes were also collected as factors related to malnutrition. The causal mediation analysis was used with malnutrition factors as the exposure, dysphagia as the outcome, and ADL as the mediation factor. In total, 391 residents (55.5%) were at risk of malnutrition and 451 residents (64.0%) had dysphagia. The average causal mediation effect (ACME) of risk of malnutrition on dysphagia was 0.07 (95% confidence interval, C, 0.07-0.08), and the ACME of BMI < 18.5 was 0.05 (95% CI 0.04-0.05, P < 0.001 for both). For insufficient nutritional intake, the ACME of low energy intake was 0.07 (95% CI 0.07-0.07), and the ACME of low protein intake was 0.03 (95% CI 0.02-0.04, P < 0.001 for both). The total effects of all these exposures on dysphagia were significant (P = 0.002 for low protein intake and P < 0.001 for the others). Malnutrition factors were associated with dysphagia, mediated by adecline in ADL among nursing home residents. The results of this study suggest the importance of nutritional management along with approaches to ADL to prevent dysphagia.

Impact of radiotherapy on body weight in head and neck cancer patients: A prospective study.

Patients with head and neck cancer (HNC) undergoing radiotherapy or chemoradiotherapy often experience symptoms that affect their ability to eat. This study aimed to explore the impact of radiotherapy on body weight in HNC patients and compare the characteristics of patients receiving enteral tube feeding with those maintaining an oral diet. In this prospective study, 52 patients with HNC were examined at diagnosis, at the start and end of radiotherapy, and six weeks after end of treatment. The nutritional assessment included measurements of body weight, food intake, and malnutrition using Patient-Generated Subjective Global Assessment (PG-SGA). Other variables were retrieved from the electronic patient record. Critical weight loss (defined as >5% from start of radiotherapy) was present in 60 % of the patients at the end of radiotherapy, and only half of these patients received any enteral nutrition therapy. The mean weight loss was 5.8% during radiotherapy, and an additional 2.1% at follow-up (n=48). A nasogastric feeding tube was used by 42% at the end of radiotherapy, and 29% at follow-up. The tube feeding users had a lower energy intake and higher weight loss than non-tube feeding users (22 vs 27kcal/kg body weight, 7.8 vs 4.4% weight loss) at the end of radiotherapy treatment. According to PG-SGA, 92% of the patients were malnourished at the end of treatment and 71% at follow-up (p<0.001). Critical weight loss and malnutrition were common in HNC patients after radiotherapy, and enteral tube feeding was initiated in only half of the cases with critical weight loss. Patients receiving enteral tube feeding may need closer monitoring to ensure adequate energy intake, and other treatment options may be necessary. These results emphasize the need for improved nutritional intervention during and after radiotherapy.

What Do We Know About the Energy Status and Diets of Pre-Professional and Professional Dancers: A Scoping Review.

Dancers require adequate nutrition support for growth and development during the pre-professional stage, as well as to fuel classes and rehearsals and to enhance performance for both pre-professional and professional dancers. The aim of this study is to understand the energy status and diet of pre-professional and professional dancers in the genres of ballet, contemporary, musical theatre, and opera. Electronic databases (n = 9) and grey literature were searched for primary studies with no time limit. Screening and data extraction were completed by two reviewers. Twelve studies were included for pre-professional (n = 7) and professional (n = 5) dancers. The genres identified were ballet (n = 11) and contemporary (n = 1), with no studies on musical theatre or opera. Studies on pre-professional ballet and contemporary dancers indicated a negative energy balance and low energy availability. Pre-professional ballet dancers had lower energy intakes than professional dancers. Professional dancers had lower BMI and body fat percentages. Macronutrients were mostly reported using the acceptable macronutrient distribution range for carbohydrates (38-56%E), protein (12-17%E), and total fat (26-42%E). Iron and calcium were the main micronutrients of concern. Accredited sports dietitians are recommended to support pre-professional and professional dancers to optimize their diet for health and performance. Further investigation is needed to quantify and assess dancers' dietary intake using sports nutrition guidelines for reference.

Fad diets for non-dialysis chronic kidney disease patients: Can "the miracle diet" be a threat?

In the pursuit of an effortless "miracle cure", there has been a significant increase in the proliferation of fad diets. These diets generally exclude a food group or macronutrients and may also restrict energy intake; they become popular quickly but often lack substantial scientific evidence to support their efficacy and safety. They only show short-term results rather than promoting a lifestyle change. Fad diets are nutritionally unbalanced and can be dangerous for some individuals. Most fad diets are generally restrictive in carbohydrates, high in protein, or unbalanced and have low energy intake, which can harm patients with early stages of chronic kidney damage (CKD) who need a low-protein diet with adequate energy intake. This narrative review discusses the risk of fad diet prescriptions for non-dialysis CKD patients.

Sociodemographic and clinical factors associated with low muscle mass and composition in people treated with (chemo)radiotherapy for lung cancer.

This study examined (1) associations between sociodemographic and clinical variables with low muscle mass and radiodensity and their loss relative to treatment commencement in patients with lung cancer; and (2) the magnitude of change in muscle mass and association with treatment outcomes and survival. Prospective study in patients planned for curative (chemo)radiotherapy for lung cancer. Low skeletal muscle mass and radiodensity and muscle loss were determined from pre- and post-treatment computed tomography images. Sociodemographic, clinical, functional, nutritional, physical activity and alternate body composition were assessed pre-treatment. Logistic and linear regression and Fisher's exact tests were used to assess associations between variables and study outcomes. Cox proportional hazards models were fitted to examine associations with survival. Overall, 53 patients (62.3% male) with a mean age of 69 ± 9.3 years and 54.8% with stage III disease were included. Pre-treatment low calf circumference was associated with pre-treatment low muscle mass (p = 0.006). Higher comorbidity scores pre-treatment were associated with normal muscle radiodensity pre- and post-treatment (p = 0.015, p = 0.027, respectively). Pre-treatment low energy and protein intake were associated with low muscle radiodensity post-treatment. Muscle mass and radiodensity were not associated with survival or treatment outcomes. In patients with lung cancer, there is some evidence anthropometric measures of muscle mass are suggestive of low muscle mass pre-radiotherapy, while low energy intake pre-treatment may indicate low muscle radiodensity after treatment. However, these findings are limited by the small sample size and further prospective studies with larger samples are required.

Is underweight associated with poorer diet, nutrient status, bone and cardiometabolic health, and school performance in Danish 8-11-year-olds?

PurposeUnderweight, i.e. low body mass index for age and sex, may indicate undernutrition, but despite high prevalence, this aspect is largely overlooked in children in high-income countries. We explored if dietary intake, nutrient status, body composition, bone mineralization, cardiometabolic markers and school performance differed in schoolchildren with underweight compared to normal- and overweight.MethodsWe used cross-sectional data from 815 Danish 8-11-year-old children collected in 2011. Intake of foods, macronutrients and key micronutrients (vitamin D, vitamin B12, calcium, iron, zinc and selenium) was assessed by 7-day dietary records. Measurements included anthropometry, dual-energy X-ray absorptiometry and tests of attention and reading skills. Fasting blood samples were analyzed for biomarkers of iron, long-chain n-3 fatty acids and vitamin D status as well as blood lipids, insulin and growth markers.ResultsEighty-three (10.2%) children had underweight and were shown to have a lower intake of energy, red meat, protein and zinc and higher intake of added sugar than children with normal- and overweight. They also had higher fish intake relative to overweight, but blood biomarkers did not differ between groups. Children with underweight had lower fat percent and bone mineralization compared to peers with normalweight, but apart from lower insulin, they did not differ in overall cardiometabolic health or school performance.ConclusionAlthough we found some differences in diet, there were no considerable differences in nutrient status, cardiometabolic health or school performance between children with underweight and their normalweight peers. However, the lower bone mineralization is a concern and needs further investigation.

Associations between the EAT-Lancet Index, nutrient intake and compliance with UK dietary guidance in UK adults

The EAT-Lancet Commission has identified a diet that aims to optimise both human health and environmental sustainability, known as the “planetary health diet”, which aims to improve the health of the population and meet sustainable food production targets by 2050(1). However, evidence suggests that following the planetary health diet may lead to micronutrient deficiencies associated with a plant-based diet(2). This research explores associations between adherence to the planetary health diet (assessed by the EAT-Lancet Index), habitual diet and adherence to dietary guidance in UK adults.Data from disease-free UK adults aged ≥18 years (n = 425) was pooled from five cross-sectional analyses that recorded habitual dietary intake using the eNutri food frequency questionnaire (FFQ)(3). Using daily nutrient and food group intakes from eNutri, EAT-Lancet Index scores were calculated(4), where higher scores represent greater adherence to the planetary health diet, which were then stratified into quartiles (Q), with the highest scores in Q4. Nutrients of interest were energy, total fat, saturated fats (SFA), protein, carbohydrates and free sugars, (all percentage of total energy (%TE)), long-chain n-3 polyunsaturated fats, fibre, sodium, potassium, calcium, iron, zinc, iodine, selenium, and vitamins B12 and D. ANCOVA (adjusting for sex, age, physical activity, ethnicity, employment status, and body mass index (BMI)) compared nutrient intakes across quartiles. If significant (p≤0.01), pairwise comparisons with Bonferroni correction identified significant differences between Q1 and Q4 (p≤0.01 accounting for multiple comparisons; results shown below). Percentages of each quartile group (Q1-Q4) meeting UK dietary guidelines were also calculated and compared using Chi-square tests (p≤0.05 for significance).Study participants had a mean (SD) age of 44 (19) years and a BMI of 25.7 (6.0) kg/m2 and 79.6% were female. Compared to Q1, Q4 had lower intakes of energy (-335 kcal/d), SFA (-3.0 %TE), free sugars (-4.2 %TE), sodium (-454 mg/d), and vitamin B12 (-2.2 mg/d) (all p≤0.006), while intakes of dietary fibre were 8.8 g/d higher (p&lt;0.001). Furthermore, those with the highest EAT-Lancet scores were more likely to meet the UK dietary recommendations for total fat (36.2% in Q4 vs 24.3% in Q1, p = 0.035), free sugars (29.5% vs 13.0%, p = 0.001), sodium (66.7% vs 46.1%, p = 0.008), and potassium (61.9% vs 49.6%, p = 0.02).The highest EAT-Lancet Index scores were associated with more favourable intakes of dietary fibre and lower energy, SFA, free sugars, and sodium, and more participants met the UK dietary recommendations for free sugars and sodium compared with the lowest scores. Although intakes of vitamin B12 were lower with higher EAT-Lancet scores, the percentage of participants consuming the recommended intakes did not differ between quartiles. These findings suggest that greater adherence to the planetary health diet is associated with a more healthful diet that aligns more closely with dietary guidance in UK adults.

Organoleptic Characteristics of Food Bars with Substituted Tempeh and Tofu Waste as Snacks for Obese Adolescents

The nutritional issues among adolescents included both undernutrition and overnutrition. Undernutrition was generally caused by low energy intake from food compared to the energy burned by the body, while overnutrition occurred when energy intake exceeded energy expenditure. These nutritional problems also influence adolescents' body image. This research aimed to develop food bar products made from tempeh and tofu waste as snacks for obese adolescents. The research process began with the preparation stage of raw materials, including drying tofu waste. Subsequently, food bars were made using three formulas: F1 (60% dried tofu waste and 40% tempeh), F2 (70% dried tofu waste and 30% tempeh), and F3 (80% dried tofu waste and 20% tempeh). The third stage involved organoleptic testing with 30 untrained panelists, using a preference test for attributes of texture, color, aroma, and taste, with a hedonic scale ranging from 1 (dislike extremely) to 4 (like extremely). Statistical analysis was conducted using ANOVA and Duncan's Test with a confidence level of 95%. The results showed that the panelists preferred food bar product F3 based on texture, color, and aroma attributes, while, F1 received the highest rating. Overall, F3 was deemed the most favored. The conclusion of this study indicated that the recommended food bars as snacks for obese adolescents were F3 (80% dried tofu waste and 20% tempeh), with an average liking score of 3 (like).

Feeding difficulties, food intake, and growth in children with esophageal atresia.

Challenges regarding feeding difficulties and nutrition in children with esophageal atresia (EA) have been sparsely studied. The aim of this study was to explore parent-reported feeding difficulties in children with EA by applying Montreal Children's Hospital-Feeding Scale (MCH-FS), and to further explore associations between feeding difficulties and clinical factors, growth and nutritional intake. Parents of EA children born between 2012 and 2017 were invited. Clinical data were collected from medical records. In a prospective cohort-study parent-reported feeding difficulties (by MCH-FS) were reported at two assessments, and at the second assessment, dietary data were collected by using the 24-h food-recall method. Out of 55 eligible participants, we evaluated 53 children at median age of 1.6 years (Q1:Q3 1.0:2.9) (first assessment) and 38 at median age of 4.2 years (Q1:Q3 1.0:2.9) (second assessment). Feeding difficulties were reported by 34% and 31% of the parents, respectively, but no particular profile of concerns could be identified. Children's energy intake and weight-for-age were correlated with feeding difficulties (MCH-FS total score) (p < 0.02). Parent-reported feeding difficulties were identified in one-third of children with EA and related to low energy intake and low weight-for-age, but not to clinical factors. This implies that feeding difficulties must be screened for during follow-up in all EA children and may facilitate early detection of challenges and intervention if needed.

Energy Availability and Body Composition in Professional Athletes: Two Sides of the Same Coin

Background/Objectives: Energy availability (EA) is essential for maintaining physiological functions, significantly influencing athletes’ health and performance. Nutritional behaviors, however, vary across sports. This study aims to assess EA levels in athletes from different disciplines, focusing on the relationship between EA and body composition in endurance athletes compared to rugby players. Methods: This study involved 18 endurance athletes (15 men, 3 women) and 36 rugby players (all men). Data were gathered through interviews, questionnaires, and bioimpedance analysis. Energy intake (EI) was measured with a 24 h dietary recall, and exercise energy expenditure (EEE) was calculated using the IPAQ questionnaire. EA was calculated as EA = (EI − EEE)/fat-free mass (FFM), with results categorized into clinical, subclinical, and optimal ranges. Results: The endurance group had a lower average FFM (57.81 kg) compared to the rugby players (67.61 kg). EA was also significantly lower in endurance athletes (11.72 kcal/kg FFM) than in rugby players (35.44 kcal/kg FFM). Endurance athletes showed more restrictive nutritional behavior with lower EI and higher EEE, but both groups maintained body composition within normal ranges. Conclusions: Endurance athletes exhibit greater nutritional restrictions compared to rugby players, though their body composition remains healthy. Further research is required to investigate the long-term effects of low EA on performance, injury risk, and potential impairment when EA falls below the optimal threshold of 45 kcal/kg FFM/day.

The association between early postoperative food intake and postoperative hospital length of stay in patients undergoing cardiac surgery: A retrospective observational single-center study

Background & AimsPerioperative nutritional status is critical during the postoperative recovery process in patients undergoing cardiac surgery. Several studies on patients undergoing cardiac surgery have reported low energy intake in early postoperative food intake via oral nutrition; however, no study has shown an association of low energy intake with postoperative hospital length of stay (LOS). This study aimed to determine whether early postoperative low food intake was associated with prolonged postoperative hospital LOS in patients undergoing cardiac surgery. MethodsThis was a retrospective, observational, single-center study conducted in patients aged ≥18 years undergoing elective cardiac surgery from January 1, 2020, to May 31, 2023. Patients were categorized by food intake as food intake < 50% (low food intake group) and ≥ 50% (adequate food intake group) at lunch on postoperative day (POD) 3. The primary outcome of this study was the postoperative hospital LOS. A generalized linear model was used to examine the association between food intake and postoperative hospital LOS using the following explanatory variables: age, European System for Cardiac Operative Risk Evaluation (EuroSCORE) II value, preoperative risk of malnutrition, activities of daily living status, Sequential Organ Failure Assessment score, and C-reactive protein level. ResultsOf the 315 patients, 104 (33.0%) had a food intake of <50% on POD3. There were no significant differences in age, sex, EuroSCORE II value, and comorbidities between the two groups. Patients in the low-food intake group had a significantly lower Barthel Index (6.7% vs. 1.4%, p = 0.017) and a higher malnutrition risk according to the Mini Nutritional Assessment Short Form score (40.4% vs. 28.2%, p = 0.043). Food intake of <50% on POD3 was associated with prolonged postoperative hospital LOS (β = 1.135 [95% confidence interval: 1.004–1.262], p = 0.018). ConclusionsLow food intake on POD3 is associated with prolonged postoperative hospital LOS in patients undergoing elective cardiac surgery. Early postoperative food intake should be closely monitored in patients after elective cardiac surgery.

Longitudinal comparison of the relationship of energy intake with body composition and physical performance in elite female basketball and volleyball players

Abstract Purpose To maximise sporting success, disciplines such as basketball and volleyball need to improve their methods of analysing the sporting performance and fitness of their athletes. Although energy intake quantities have been established at a theoretical level for women to perform at a sporting level, it has been found that these energy intake levels are not met or followed and that, despite this, the performance of female players is not diminished. Thus, the purpose of this research study was to describe and compare the anthropometric characteristics of these two disciplines and to identify the differences in actual and theoretical energy intake, as well as to observe physical performance in both disciplines. Methods Anthropometric data, continuous quantitative data, training time and characteristics, and energy intake data were collected. Performance tests included upper and lower body strength, speed, agility, and endurance tests. Dietary monitoring showed lower intakes of total energy, carbohydrate and protein than theoretically recommended. However, the athletes experienced overall improvements in performance and body composition. Results The mean total energy intake was 20.2 ± 4.3 kcal·kg−1·day−1. The minimum individual mean intake was 9.8 kcal·kg−1·day−1 and the maximum was 25.95 kcal·kg−1·day−1. Carbohydrates accounted for 54.3% ± 8.8% of the energy intake; 20.3% ± 6.5% from fats; 25.4% ± 5.7% from proteins. Conclusions Current data suggest that, although a cause-effect relationship between dietary intake and BC performance cannot be determined, elite athletes in these sports disciplines may experience beneficial outcomes despite having lower total energy, CHO, protein, and fat intakes than previously recommended in the literature.

Association between dopamine genes, adiposity, food addiction, and eating behavior in Chilean adult.

A frequent consumption of high sugar/fat foods can affect dopamine signaling in the brain and cause sustained stimulation of the reward system. It has been hypothesized that a hypodopaminergic trait results in an individual overeating in order to increase brain DA. Genetic variants in this route have been connected with addiction and eating behaviors. Most studies focus on a specific SNP, and few studies have used multilocus genetic scores, which quantify genetic risk on a continuum. To assess the relationship between multilocus genetic scores based on multiple gene variants in the dopaminergic pathway and measurements of anthropometry, eating behavior, food reinforcement, and food addiction (FA) in Chilean adults. We recruited 221 Chilean adults for a cross-sectional study. A standard anthropometric measurement procedure was followed and eating behavior was examined using the Three Factor Eating questionnaire (TFEQ), Food Reinforcement Value Questionnaire (FRVQ), Yale Food Addiction Scale (YFAS) and 24-h diet recall. Multilocus genetic scores were calculated using TaqMan assays (rs1800497-rs1799732-rs6277-rs4680). No differences were found in the entire sample for anthropometric measurements, by MLGS. We found that participants with a score ≥ 2.0 in the MLGS showed higher food choices on the RVFQ and lower energy intake in protein, lipids, SAFA, MUFA, PUFA, dietary cholesterol, omega-3 and Omega-6 fatty acids in the 24-h recall (p < 0.05). Stratified by nutritional condition, the group with obesity had inferior scores on cognitive restriction, greater scores on uncontrolled eating, emotional eating, and responding to palatable food in the RVFQ. Also, in subjects with obesity, there was more food addiction in the group scoring "MLGS ≥2.0 or low dopamine signaling" (53%), compared to the group scored "MLGS <2.0 or high dopamine signaling" (23%) (p-value; 0.05). Emotional Eating scores correlated positively with MLGS in subjects with obesity. In adults with obesity, the MLGS of the dopamine pathway, reflecting hypodopaminergic signaling, was associated with greater scores on food addiction and altered eating behavior traits.

Dietary intake, energy availability, and power in men collegiate gymnasts.

The purpose was to examine the prevalence of low energy availability (LEA), explore dietary behaviors in men collegiate gymnasts (n = 14), and investigate the relationships between energy availability (EA), body composition, and plyometric performance. Body composition was measured using air displacement plethysmography. Lower- and upper-body peak power (PWRpeak) and modified reactive strength index (RSImod) were calculated from countermovement jump (CMJ) and plyometric push-up (PP) assessments. Energy expenditure was tracked over 3 days, while daily energy and macronutrient intake were recorded. EA was calculated and used to categorize athletes into LEA and non-LEA groups. Pearson correlation coefficients were used to examine relationships between EA, body composition, and performance metrics. 85.7% of athletes (n = 12) exhibited LEA (20.98 ± 5.2 kcals/kg FFM), with non-LEA athletes (n = 2) marginally surpassing the <30 kcal/kg of fat-free mass (FFM) threshold (30.58 ± 0.2 kcals/kg FFM). The cohort (n = 14) consumed insufficient energy (30.5 ± 4.5 kcal/kg/day) and carbohydrates (3.7 ± 1.1 g/kg/day), resulting in LEA (22.36 ± 5.9 kcal/kg/FFM). EA was not correlated with body composition or performance metrics. A high prevalence of LEA may exist in men gymnasts, largely due to a low relative energy and carbohydrate intake.

478 Impact of crude protein and phosphorus deficiencies on liver mitochondrial content and transcriptome in growing Merino wethers

Abstract In grazing systems in Northern Australia, crude protein (CP) and phosphorus (P) availability varies, affecting ruminant production due to voluntary reduced intake and therefore body weight (BW) gain. We were interested in understanding metabolic regulation in this model system, both in terms of a) identifying key tissues, and b) detecting any modifications in mitochondrial physiology, given the central role of this organelle in bioenergetic homeostasis. Merino wethers (n = 24) were subjected to three dietary regimens: High CP, High P, (Control), Low CP, Low P (Deficient), and High CP, High P, with restricted feed intake (Restricted). Mitochondrial DNA (mtDNA) copy numbers, indicative of mitochondrial content, were measured via qPCR. Transcriptomic analyses through RNA sequencing targeted mitochondria-associated gene expression changes and pathways, using the MitoCarta 3.0 database. There was a significant decrease of mtDNA copy numbers in the liver of sheep under either Deficient and Restricted diets (P &amp;lt; 0.01), with as much as a 2-fold difference between the Control and Deficient diets. This may suggest reduced mitochondrial biogenesis as an adaptation to decreased energy intake. When compared with the Control group, both the Deficient and Restricted groups upregulated pathways related to vitamin metabolism (Log2FC: 0.231 and 0.449) and folate and 1-C metabolism (Log2FC: 0.409 and 0.706). However, impacted pathways shared between these two comparisons (Control v Deficient, Control v Restricted) also include choline and betaine metabolism, amino acid metabolism, and glycine metabolism, which suggests similar mechanisms being impacted by decreased energy intake, regardless of whether it is due to satiety from nutrient deficiency or restricted feed intake. Notably, the creatine metabolism pathway was uniquely upregulated in the Restricted group compared with the Deficient group (Log2FC: 0.114), although the CKMT2 gene was upregulated in the Restricted group compared with both the Control and Deficient group (Log2FC: 1.30 and 0.879). Additionally, the SLC25A family pathway, responsible for mitochondrial metabolite transport, was found to be upregulated in the Restricted group when compared with both Control and Deficient groups (Log2FC: 0.33 and 0.865). Overall, this study demonstrated a pronounced decrease in mitochondrial content in the liver of growing Merino wethers subjected to nutritional deficiencies and feed restriction. Multiple metabolic pathways were shared between the comparisons of the Control diet group to both Deficient and Restricted nutritional treatments. However, the SLC25A transporter family pathway was uniquely upregulated in the Restricted group compared with either an optimal or deficient diet. The regulation of these metabolic pathways is a subject of further study that may represent a systemic response to maintain homeostasis while undergoing significantly lower energy intake, with implications for animal growth, tissue deposition, and energetic maintenance. Understanding distinctions in the response to feed restriction and nutrient deficiency induced reduction in intake may help improve production strategies for ruminants grazing in these conditions.

Menstrual Dysfunction in Adolescent Female Athletes.

Despite the benefits of exercise on mental and physical health, excessive training loads can lead to health problems in the long term, including a wide spectrum of menstrual dysfunction (MD). This narrative review aims to analyze the relationship between physical exercise and MD in adolescent female athletes to support regular menstrual health monitoring and promote educational programs on reproductive risks. When dealing with MD in young athletes, several factors entangled with maturation of the hypothalamus-pituitary-ovarian axis should be considered. Firstly, some disciplines seem to have a higher prevalence of MD due to the high loads of training regimes and the early introduction of athletes to a competitive career. Moreover, low energy intake and a low body mass index appear to exacerbate existing MD. Lastly, disordered eating behaviors and psychological stress can contribute to MD in female athletes. The type of sport, influencing the intensity and duration of exercise, as well as individual psycho-physiological and environmental factors, may influence the role of physical activity in the manifestation of MD. Early recognition and management of MD, along with collaboration between sports organizations and health professionals, are crucial to minimize risks, ensure proper nutrition, and balance training with recovery. Keeping an open discussion on the topic may prospectively improve awareness, early diagnosis, and treatment strategies, as well as reduce injury risk and enhance sports performance.