This article proposes a method for estimating the Doppler power spectrum (DPS) of a weather radar via minimum mean square error (MMSE). In order to detect severe weather phenomena that mostly occur within the lowest few kilometers of the atmosphere, weather radars have to direct their beams at low elevation angles, and the received signals from such observations usually contain reflections from the ground and buildings, so-called ground clutter. The MMSE estimator, which is an adaptive spectral estimator, allows weather radar DPSs to be obtained with excellently reduced ground clutter contaminations. The MMSE estimator was examined by numerical simulations, which supposed various precipitation and ground clutter scenarios and DPS estimation parameter values. The MMSE estimator provided DPSs almost as accurate as those from the traditional Fourier and windowed Fourier estimators in simulations with no ground clutter and much better DPSs than those estimators in the presence of ground clutter. Furthermore, the MMSE estimator gave better suppression of ground clutter contamination than the Capon estimator, which is another adaptive spectral estimator. As a result of statistical evaluations, ground clutter signals with a strong clutter-to-noise ratio of 70 dB appeared only in a narrow velocity range of the MMSE DPS, from −2 to 2 m/s, and caused degradation of the mean and standard errors outside this velocity range by just 1 dB. The MMSE estimator was also applied to signals received by actual weather radar, and DPS estimation of precipitation signals with similarly low ground clutter contamination was demonstrated.