Low Region Research Articles

Distinguishing factors in regional variations of TAVI in Japan: the unique role of administrative facility standards compared to other procedures in a high-cost medical care subsidy system

Abstract Background Transcatheter aortic valve implantation (TAVI) is less invasive than surgical aortic valve replacement and is becoming increasingly popular worldwide, particularly among patients with aortic valve stenosis (AS) due to aging. However, regional differences are expected to exist not only between countries but also within a single country. Reports from Western countries indicate the presence of regional differences in TAVI and the reasons for these differences, which include differences in medical infrastructure, economic resources, health insurance systems and policies, geographic factors, and availability of specialized medical personnel. TAVI is expensive, but in Japan, the economic aspect is relatively unimportant due to the high-cost medical assistance system. Furthermore, there is little socioeconomic disparity between regions. In such a society, we have reported that the number of specialists and resources for PCI can explain regional differences in ablation and endovascular treatment (EVT). However, unlike those other cardiovascular procedures, there are specific requirements for facilities to perform TAVI, such as the number of transesophageal echocardiographies, as well as cardiologists and cardiovascular surgeons, and the equipment itself, such as hybrid operating rooms. We examined how these facility requirements, which are thought to be controlled by the government, are related to regional differences in TAVI implementation. Methods and Results We used the Japanese Ministry of Health, Labour and Welfare national database to determine the rate of TAVI for patients with AS performed per 100,000 population aged ≥40 years in all 47 prefectures in 2022. A linear regression model was developed to assess factors contributing to the regional medical supply, including the rates of PCI per 100,000 population aged ≥40 years and the numbers of cardiologists, cardiovascular surgeons, cardiovascular intervention and therapy training facilities, cardiovascular surgery base facilities, and TAVI facilities. The numbers in the highest and lowest regions were 26.6 and 3.9 (a 6.8-fold difference) for TAVI number. The number of TAVI facilities contributed most significantly to the TAVI volumes (P = 0.0105), while the rates of PCI and other factors did not contribute significantly. The number of TAVI facilities was positively correlated with the number of transesophageal echocardiographies the most (r = 0.353). Conclusion This study revealed large regional variations in TAVI volumes in Japan, of which administrative facility standards were a major determinant.

Effect of Filler Wire Composition on Weld Metal Microstructure and Mechanical Properties in X80 Steel Laser Welds

Laser welding was performed using different filler wires, ER70S steel, commercially pure iron, and pure nickel filler, in the context of welding X80 pipeline steel to assess the microstructure and mechanical properties of the weld metal. Introducing an ER70S wire promoted acicular ferrite formation in the fusion zone, compared to a bainitic microstructure in an autogenous laser weld. The use of pure iron wire was considered as a potential strategy for reducing hardenability, as it led to the dilution of alloying elements in the fusion zone, increasing ferrite content and reducing weld metal hardness to a level compliant with API pipeline standards. The addition of pure nickel wire was used to reveal the degree of weld metal mixing imposed by the laser (thus providing an unambiguous tracer element) when it is combined with filler material dilution in the fusion zone, revealing that the upper region contained 38% wire material and the lower region only 12%. This accounts for the differences observed between the upper versus lower portions of the weld metal when other wires are used, and the use of hardness mapping and micro-indentation demonstrates the correlation between the variations in mechanical properties and microstructural differences introduced by incomplete mixing of the filler wire elements.

The projected global burden of modifiable risk factors on cardiovascular disease from 2025 to 2100

Abstract Background Cardiovascular diseases (CVDs) are the primary cause of global mortality and morbidity. Controlling modifiable risk factors driving the CVD epidemic is a vital focus of primary prevention efforts worldwide. Understanding the epidemiological trends in these risk factors is therefore essential in designing effective countermeasures against CVDs for the years to come. Purpose This study aims to forecast the disability-adjusted life years (DALYs) associated with CVDs attributable to high systolic blood pressure (SBP), high body-mass index (BMI), high fasting plasma glucose (FPG), high low-density lipoprotein (LDL) and tobacco use from 2025 to 2100, stratified by GBD super-regions, sex, sociodemographic index (SDI), and age-groups. Methods Historical data on DALYs from 1990 to 2019 from the Global Burden of Disease (GBD) study was used to project DALYs associated with modifiable risk factors of CVDs from 2025 to 2100. Trends across GBD super-regions, sex, SDI, and age-groups were also examined. Results Between 2025 and 2100, age-standardised DALY rates (ASDR) per 100,000 population are forecasted to fall across all modifiable risk factors, with the greatest decline seen in tobacco use (-76.0%) and high LDL (-66.9%). Globally, high SBP and high BMI expect the greatest ASDR in 2100 (both 891 per 100,000 population), while tobacco use expects the least (213 per 100,000 population). High BMI is expected to rise 623.0% in South Asia and 221.5% in South-east Asia, East Asia and Oceania from 2025 to 2100, while high FPG is expected to rise 114.2% in North Africa and the Middle-east and 110.6% in South Asia. Females are expected to have lower overall and greater reductions in ASDR across all modifiable risk factors when compared to males from 2025 to 2100. Notably, males expect a 11.0% rise in high BMI worldwide across this period. The age-prevalence of modifiable risk factors is expected to be bimodal in 2100, highest in those aged 50-59 as well as 75-84 years old, possibly suggesting improvements in global screening efforts or the earlier development of metabolic dysfunction. All modifiable risk factors are predicted to fall in high and high-middle SDI regions from 2025 to 2100. In contrast, low, low-middle, and middle SDI regions expect a rise in high FPG and high BMI across this same time frame. The burden of modifiable CVD risk factors is expected to be highest in low-middle SDI regions in 2100, as compared to high-middle SDI regions in 2025. Conclusion While the global decline in ASDR of modifiable risk factors suggests overall improvements in the primary prevention of CVDs, regional spikes in high BMI and FPG calls for the implementation of timely, targeted interventions accounting for local trends in CVD. Moreover, the disproportionate metabolic burden expected in lower SDI regions in the coming decades requires concerted, international support to alleviate the global burden of CVDs.

Simulation study on the cavitation flow characteristics of liquid ammonia in the nozzle under high-pressure injection conditions

In this study, a non-isothermal compressible cavitating flow simulation model for liquid ammonia in high-pressure injector, accounting for the phase change properties, was established. The model was validated using experimental data from existing literature. The cavitation phase change process of liquid ammonia within the injector nozzle was investigated, and the differences in cavitation distribution between ammonia and diesel were explored. The results indicate that with increasing injection pressure, the vapor volume fraction of ammonia increases linearly, while that of diesel fuel shows a rapid initial rise followed by a decelerating trend. In terms of flow coefficient, ammonia is lower than diesel, though the two values converge at higher injection pressures. Under low injection pressure, the heat absorbed by the cavitation phase change of ammonia exceeded the heat generated by the high-speed friction of ammonia flow against the nozzle wall, leading to a temperature drop at the nozzle inlet. Conversely, at high injection pressure, the temperature of ammonia on the nozzle wall increases by more than 20 K, resulting in a rapid rise in saturated vapor pressure and significantly intensifying the cavitation effect. Compared to ammonia, diesel experienced a higher temperature rise within the nozzle but exhibited smaller variations in saturated vapor pressure, making the temperature effect on cavitation less pronounced. Diesel’s higher density and viscosity resulted in lower flow velocities compared to ammonia, leading to more developed cavitation in the lower wall region of the nozzle and creating a higher pressure region on the upper wall of the nozzle, which was more distant from the nozzle inlet and inhibited cavitation development there. The research results provide theoretical support for the design of liquid ammonia injectors.

Inorganic composition of PM2.5 in the lower northern region of Thailand and their potential impact on human health

Inorganic composition of PM2.5 in the lower northern region of Thailand and their potential impact on human health

Potentiality of Nano Pb2O3–Enhanced Cement as a Nuclear Radiation Shield for Radiation Therapy Facilities

In the present investigation, the gamma and neutron shielding parameters of nano Pb2O3 incorporated into cement in proportions ranging from 0 to 5 wt% were determined using EpiXS and NGCal software. It was observed that the mass attenuation coefficient decreased with increasing photon energy. The introduction of higher concentrations of nano Pb2O3 into the cement resulted in a marked increase in the Pb K-edge. Cement samples enhanced with Pb2O3 content exhibited a pronounced peak in the effective atomic number in the lower energy regions. The exposure buildup factor showed a decrease in its value with increasing Pb2O3 content. Among the compositions used, pure cement with no Pb2O3 addition demonstrated a superior mass attenuation factor for both thermal and fast neutrons. A blend of 95% cement with 5% Pb2O3 emerged as the most effective gamma-ray shielding material within the tested energy range. A comparative analysis of this mix with other concrete types was conducted to evaluate its effectiveness as a shielding material. The findings suggest that this composition could benefit medical imaging and radiation therapy facilities.

SiamVIT: A patchwise network for gamma-ray point source detection

Conventional point source detection methods generally work in a pixelwise manner and can hardly exploit the overall semantic information of sources; consequently, these methods usually suffer from low precision. In this work we achieve point source detection in fully patchwise mode by proposing a siamese network called SiamVIT that includes a visual transformer (VIT). SiamVIT can effectively and accurately locate point sources from gamma -ray maps with high purity not only in higher flux regions, but also in lower flux regions, which is extremely challenging to achieve with state-of-the-art methods. SiamVIT consists of two VIT branches and a matching block. In the feature extraction stage, gamma -ray maps are fed into one VIT branch to obtain patch representations with adequate semantic and contextual information, whereas detection templates with location information are fed into the other branch to produce template representations. In the location stage, a patch representation and all template representations are fed into the matching block to determine whether the associated gamma -ray map patch contains a point source and where that point source is located, if applicable. We compare our proposed SiamVIT with the current advanced methods and find that SiamVIT has significantly better purity and completeness and a superior Dice coefficient on the test set. In addition, when point sources overlap, SiamVIT can better distinguish different point sources.

Quantifying Pleistocene loess provenance in midcontinental North America using a mixing model: Implications for glacial lobe evolution along the southern Laurentide ice sheet

Quaternary glaciations have significantly impacted the midcontinental North American landscape, leaving behind a proglacial sediment record of glacial lake deposits, glacio-fluvial sand and gravel, and windblown loess. This paper aims to expand upon a previous study using detrital zircon provenance analysis to investigate midcontinental North American loess provenance in relation to the glacial history of the southern Laurentide ice sheet during the middle to late Pleistocene. The study incorporates previously published detrital zircon data from last glacial tills (representing the Huron-Erie Lobe, Lake Michigan Lobe, Green Bay Lobe, Superior Lobe, Des Moines Lobe, and James Lobe), middle to late Pleistocene loess from several sites along the Illinois and Mississippi River valleys, and suspended sediment load inputs from the Missouri River and Arkansas River. A statistical mixing model (DzMix version 2.2) was used to estimate the relative proportions of glacial and nonglacial sources to Wisconsin Episode, Illinois Episode, and pre–Illinois Episode age loess. We show that mixing models that include the modern suspended sediment loads of the Missouri and Arkansas Rivers significantly improve (up to 23% increase in cross-correlation value) the source characterization of Wisconsin Episode (last glacial) and Illinois Episode (penultimate glacial) loess deposits within the Mississippi River drainage basin. These river sources are dominant inputs for certain loess sites (as much as 51%), but their relative contributions are not static across time and space, which has implications for temporal and spatial differences in relative sediment source estimates and glacial and fluvial sediment transport evolution. Specifically, differences in relative sediment proportion estimates among Wisconsin, Illinois, and pre–Illinois Episode loess support previous evidence for the persistence of a Quebec-Labrador ice dome source through multiple glacial cycles, even with the inclusion of river sources in updated mixing models. Illinois and pre–Illinois Episode loess in the southern portion of our study area received ~20% detrital zircon input from sources similar to the present-day Missouri and Arkansas Rivers, suggesting that these river systems were contributing a significant amount of detritus to the lower Mississippi River valley region during the middle Pleistocene.

Structural, Microstructural, Dielectric and Ac-conductivity of CaTi1-xFexO3 Multiferroic Materials Synthesized by Solid State Method

In this study, the structural, microstructural, dielectric and conductivity properties of Fe-doped CaTiO3 (CT) ceramic were investigated. These ceramics were successfully synthesized using the conventional solid-state method. The X-ray diffraction and Rietveld refinement results showed that the ceramics at x=0.0, 0.1, 0.2 and 0.3 crystalized in the orthorhombic phase with the Pmmm space group. While for x=0.4, 0.5 and 0.6, the phase formation changes from orthorhombic to tetragonal phase with P4/mmm group space. The SEM results revealed a semi-spherical shape of grain for lower Fe content (≤0.4), while at x=0.5 and 0.6 an agglomeration phenomenon is observed and the observed density of the sample at x=0.5 is higher than the other ceramics. The dielectric properties were studied as function of frequency and temperature. The dielectric permittivity (ɛ’r) decreases as function of frequency at lower frequency region and remain almost independent of frequency at high frequency region in the whole temperature range of R.T–520 °C. Each converges at high frequency (>105 Hz) for all the temperatures. The evolution of ɛ’r as function of temperature for pure CT ceramic showed a stability at large range of temperature (from R.T to 250°C). For substituted ceramics, we obtained a phase transition which shifted to the lower temperature with the increase of Fe content. And the value of ɛ’r, increases for Fe-doped CT ceramics and reaches a maximal value for x=0.5 which is 50 time bigger than the pure ceramic. The AC conductivity, σAC, is found to increase rapidly as a function of frequency, at low frequency region, and increases linearly at high frequency region, which confirms the hopping of electrons related to the conduction mechanism. The σAC evolution is found to follow the Jonscher’s law and the s exponent decreased with the increasing temperature which is related to the correlated barrier height (CBH) model. And the σAC values increase with the increases of Fe content.

Structural, Morphological, Optical and Vibrational Properties of a Novel Coral-Like Fibrous CuO Nanostructure Synthesized via Dropwise Precipitation for UV-light Induced Photocatalytic Wastewater Remediation on Aqueous R6G Dye

CuO is a well-known monoclinic structure with unique properties that is extensively investigated for sensor, energy storage, and optoelectronic applications. In this work, the CuO nanostructure was synthesized through facile precipitation by mixing the aqueous copper (II) sulfate pentahydrate with sodium hydroxide. The as-synthesized CuO was characterized by scanning electron microscopy (SEM), X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR) and UV–visible spectroscopy. A homogeneous growth of a narrow, fine coral-like fibrous morphology was observed on CuO under SEM imaging. The FTIR spectra reveal the existence of some dominant sharp bands in the lower wavenumber region that represent the Cu-O bonds. The high solubility of CuO in water confirms the formation of particles with nanoscale dimensions. CuO exhibits a strong optical absorption peak at 510 nm, and the band gap determined by Tauc's relation is 2.11 eV. CuO is capable of inducing photocatalytic degradation on R6G dye solutions under low-intensity UVC irradiation, which can serve as a future photocatalyst for wastewater treatment.

Molecular dynamics study on the influence of temperature on the mechanical properties of graphene reinforced magnesium-matrix composites

Magnesium and its alloys have been considered the lightest engineering structural metal materials, but their poor plasticity and the degradation of mechanical properties at high temperatures limit their wide application. Therefore, using molecular dynamics simulation, this work examines how the phase structure and mechanical characteristics of pure magnesium under compressive loading are affected by graphene and varying temperatures. The findings demonstrate that adding graphene can significantly increase magnesium's strength. As well as its Young's modulus, and have a great influence on the secondary strain's strengthening. It is noted that the Gr/Mg-based composites have the same plastic deformation behavior as that of pure magnesium, and both of them undergo a transition from a dense hexagonal structure to other structures during plastic deformation, and the introduction of graphene makes the transition more drastic. The number of embedded graphene layers governs the overall deformation of the Gr/Mg composites; however, it does not significantly affect the deformation behavior of the magnesium matrix in the upper and lower regions of the composites. When there is no graphene embedded, the phase transition of magnesium matrix occurs everywhere, while when graphene is embedded, the phase transition of magnesium matrix in the upper and lower parts of graphene extends along the near-interfacial position of graphene without passing through it, which means graphene has the role of changing the nucleation position of dislocations and blocking the movement of dislocations. In addition, the temperature decreases the phase transition step size of Gr/Mg composites, which is similar to that of pure magnesium, while the temperature affects the phase structure of pure magnesium Gr/Mg composites.

Mechanisms Underlying the Changes in Sporadic E Layers During Sudden Stratospheric Warming

During sudden stratospheric warming (SSW) events, significant modifications occur, not only in the neutral atmosphere, but also in the ionosphere. Specifically, sporadic E layers in the mesosphere and lower thermosphere regions significantly disrupt satellite communication. Although research has frequently focused on ionospheric alterations during SSW events, detailed studies on sporadic E layers remain limited. Examining these variations during SSW events could enhance our understanding of the interaction mechanisms between the ionosphere and the neutral atmosphere, and provide insights into the patterns of sporadic E layer alterations. This study analyzed the behavior of sporadic E layers during the 2008/2009 winter SSW period using data from three Japanese stations and satellite observations. The principal findings included the following: (1) The enhancement in the critical frequency of the sporadic E layers was most notable following the transition from easterly to westerly winds at 60° N at a 10 hPa altitude, accompanied by quasi 6-day and quasi 16-day oscillations in frequency. (2) The daily average zonal and meridional wind speeds in the MLT region also exhibited quasi 6-day and quasi 16-day oscillations, aligning with the observed periodicities in the critical frequency of the sporadic E layers. (3) Planetary waves were shown to modulate the amplitude of diurnal and semidiurnal tides, influencing the sporadic E layers. Furthermore, a wavelet analysis of foEs data with a time resolution of 0.25 h demonstrated that planetary waves also modulate the frequency of diurnal tides, thereby affecting the sporadic E layers. This research contributes to a deeper understanding of the formation mechanisms and prediction of sporadic E layer behavior.

Ecological and Anatomical Characteristics of riverbank Plants of Water Currents and Waterbodies of the Lower Amur Region

The results of an ecological and anatomical study of plants in the coastal shallows of rivers and lakes o the Lower Amur region are presented in order to identify their resistance and adaptability to the conditions of existence. 7 stenotopic species were studied. It was revealed that the vegetative organs of plants are characterized by a combination of typical hydromorphic and specific adaptive features. Adaptation of species to sandy-silty shallow habitats is carried out due to histological transformations of the main tissues. The narrow specialization of species does not affect the typical structure of plant organs and does not lead to a simplification of their internal structure. The studied species are more characterized by signs of terrestrial micromorphology (sclerification, suberinization and cutinization of tissues) rather than hydrophytic. It is assumed that a specific complex of shallow flora was formed mainly from terrestrial species.

A novel method for measuring the direction and angle of Central ray and predicting rotation center via panorama phantom.

The aim of this study is to propose and evaluate a novel method for measuring the central ray direction and detecting the rotation center of panoramic radiography using the panorama phantom. To determine the central ray direction, two points passing through the same x-coordinate in a panoramic radiograph were identified and connected. The angles formed by the central ray with the midline and the angle to the arch form were measured using mathematical calculations. Further, by analyzing the continuous changes in the central ray obtained in this manner, the movement of the rotation center was detected and visualized. The angle between the central ray and the midline exhibited a progressive decrease from the anterior to the posterior direction. With regards to the arch form, the angle of the central ray exhibited an increasing pattern as it moved from the anterior to the posterior direction, culminating in its peak value at the lower second premolar cusp region, followed by a consistent decrease. The rotation center approximately started from the distolateral aspect of the coronoid process and then anteromedially moved to the midline in a curved line passing between the mandibular notch and coronoid process. By using the panorama phantom, we successfully obtained the central ray direction and detected the rotation center of the panoramic radiography.

Novel isolates expand the physiological diversity of Prochlorococcus and illuminate its macroevolution.

Prochlorococcus is a diverse picocyanobacterial genus and the most abundant phototroph on Earth. Its photosynthetic diversity divides it into high-light (HL)- or low-light (LL)-adapted groups representing broad phylogenetic grades-each composed of several monophyletic clades. Here, we physiologically characterize four new Prochlorococcus strains isolated from below the deep chlorophyll maximum in the North Pacific Ocean. We combine these physiological properties with genomic analyses to explore the evolution of photosynthetic antennae and discuss potential macroevolutionary implications. The isolates belong to deeply branching low-light-adapted clades that have no other cultivated representatives and display some unusual characteristics. For example, despite its otherwise low-light-adapted physiological characteristics, strain MIT1223 has low chl b2 content similar to high-light-adapted strains. Isolate genomes revealed that each strain contains a unique arsenal of pigment biosynthesis and binding alleles that have been horizontally acquired, contributing to the observed physiological diversity. Comparative genomic analysis of all picocyanobacteria reveals that Pcb, the major pigment carrying protein in Prochlorococcus, greatly increased in copy number and diversity per genome along a branch that coincides with the loss of facultative particle attachment. Collectively, these observations support a recently developed macroevolutionary model, in which niche-constructing radiations allowed ancestral lineages of picocyanobacteria to transition from a particle-attached to planktonic lifestyle and broadly colonize the euphotic zone.IMPORTANCEThe marine cyanobacterium, Prochlorococcus, is among the Earth's most abundant organisms, and much of its genetic and physiological diversity remains uncharacterized. Although field studies help reveal the scope of diversity, cultured isolates allow us to link genomic potential to physiological processes, illuminate eco-evolutionary feedbacks, and test theories arising from comparative genomics of wild cells. Here, we report the isolation and characterization of novel low-light (LL)-adapted Prochlorococcus strains that fill in multiple evolutionary gaps. These new strains are the first cultivated representatives of the LLVII and LLVIII paraphyletic grades of Prochlorococcus, which are broadly distributed in the lower regions of the ocean euphotic zone. Each of these grades is a unique, highly diverse section of the Prochlorococcus tree that separates distinct ecological groups: the LLVII grade branches between monophyletic clades that have facultatively particle-associated and constitutively planktonic lifestyles, whereas the LLVIII grade lies along the branch that leads to all high-light (HL)-adapted clades. Characterizing strains and genomes from these grades yields insights into the large-scale evolution of Prochlorococcus. The new LLVII and LLVIII strains are adapted to growth at very low irradiance levels and possess unique light-harvesting gene signatures and pigmentation. The LLVII strains represent the most basal Prochlorococcus group with a major expansion in photosynthetic antenna genes. Furthermore, a strain from the LLVIII grade challenges the paradigm that all LL-adapted Prochlorococcus exhibit high ratios of chl b:a2. These findings provide insights into the photophysiological evolution of Prochlorococcus and redefine what it means to be a low- vs high-light-adapted Prochlorococcus cell.

The course of the phrenic nerve in the neck region and its relationship with adjacent anatomical structures in the thoracic inlet.

This study aims to reveal the relationship of the phrenic nerve (PhN) with its neighboring structures in the lower neck region more comprehensively than previous studies and to minimize nerve damage by enabling invasive procedures in this region to be performed with high accuracy. Forty-one heminecks were evaluated. The relationship between the PhN and the anterior scalene muscle (ASM), internal thoracic artery (ITA), branches of subclavian artery (SA) and subclavian vein (SV) was examined. It was observed that the PhN was located medial to the ASM in all cases. The distances were higher in male cadavers. The PhN was found to enter the thorax lateral to the ITA in 15/41 and medial to it in 25/41 sides. In 17/41 cases, the closest SA branch to the PhN was the thyrocervical trunk (TT) and in 24 cases the ITA. The PhN was located behind the SV in 38 cases and in front of it in 2 cases.The accessory PhN was found in 4/41 sides. There was no significant difference in morphometric findings between genders (p > 0.05). However, significant differences were observed between the parameters (p < 0.05). The anatomy and variations of the PhN are of great importance in surgical interventions and invasive procedures in the neck region. The study provides important information to reduce the risk of damage to the PhN in surgical procedures. In addition, knowledge of the anatomical variations of the nerve may contribute to more successful results in nerve grafting and other surgical applications.

An 8Tx/32Rx head-neck coil at 7T by combining 2Tx/32Rx Nova coil with 6Tx shielded coaxial cable elements.

Standard head coils used at 7T MRI suffer from high signal loss at lower brain regions and neck. This study aimed to increase the field of view (FOV) of a birdcage coil to image the lower brain regions and neck with a straightforward approach of using add-on transmit shielded coaxial cable coil (SCC) elements. A new head-neck coil was modeled as a combination of the 2Tx/32Rx Nova head coil and 6Tx SCC elements. The add-on transmit SCC elements have been produced. The full wave electromagnetic simulations were performed to analyze the coil geometry and estimate the local specific absorption ratio (SAR). The field maps and structural images were acquired in a phantom and in vivo on a 7T scanner. The computed SAR histogram revealed a peak of 4.08 W/kg. The simulated and measured maps are in good agreement. The manufactured coil's S-parameters are below 10 dB. The field measurements on a subject presented the increase in the FOV. The T1-weighted structural images of three subjects acquired with the head-neck coil showed increased coverage compared to the head coil only. Combining the 2Tx/32Rx Nova head coil and 6Tx SCC elements allowed imaging of the whole brain with an increased FOV down to the C4 spine. The coil stayed fully functional when different subjects were scanned. We conclude that the SCC transmit-only coils are a robust adjunct to conventional coil designs and can meaningfully enhance and expand their field of view.

Exploring the Uncommon: Mandibular Osteomyelitis in Pediatric Patient – A Case Report

Introduction: Osteomyelitis is often found in 60-70% of all body regions, but in the jaw area, it rarely occurs, especially in children, and with the development of antibiotics, the incidence of jaw osteomyelitis is decreasing. Osteomyelitis is an inflammatory bone condition involving the medulla and periosteum, one of the causes of which is bacterial infection. The diagnostic support with the best accuracy in this case is a CT scan, with precise imaging of the lines of the lytic lesion, medullary sclerosis, and bone sequestra. Case: A 4-year-old girl patient complained of swelling on the left cheek and a bluish colour on the chin. The patient complained of losing six primary teeth in the lower region, with greenish discharge and bad breath. CT-Scan results showed destructive lytic lesions in the ramus, angle, corpus, left mandibular symphysis, and hyperostosis. The patient was diagnosed with osteomyelitis of the mandible. Case Management: Sequesterectomy and debridement under general anaesthesia, with anatomical pathology results showing mandibular osteomyelitis due to Actinomyces sp. The patient experienced no complaints and significant healing results from treatment. Conclusion: One of the bacteria that plays a role in mandibular osteomyelitis is Actinomyces sp. Proper diagnostic support and surgical planning can determine maximum postoperative results. Keywords: mandibular osteomyelitis, pediatric, sequester ectomy, Actinomyces sp.

Simple bone cyst of the mandible: A case report with review of literature

Simple bone cyst (SBC) was first described by Lucas in 1929. It is an asymptomatic, intraosseous cyst. It falls under pseudocyst category, as it is devoid of an epithelial lining and mostly discovered accidently on routine radiograph. It commonly affects metaphyses of long bones such as humerus and femur. Other terminologies used for this lesion include Solitary bone cyst, traumatic bone cyst and hemorrhagic bone cyst. The incidence of cyst affecting the jaws is only 1%. About 89% of the lesion occurs in mandible and 11% in maxilla. The purpose of this article is to present rare occurrence of SBC in the mandibular region with review of literature. An 18 year old male patient reported with pain in right lower back teeth region. Clinically 47 was tender. Panoramic radiograph showed a radiolucent unilocular lesion in ascending ramus and mandibular body distal to 47. Diagnosis of apical periodontitis in relation to 47 and simple bone cyst mandible was made by correlating clinical, radiographic and histopathological evaluation. Surgical curettage was performed and follow up after 4 months revealed no evidence of recurrence. Simple bone cyst is rare incidental lesion of the mandible. Thorough clinical, radiological and histopathologic evaluation is helpful for diagnosis and surgical management of the lesion. Conservative management should be approached to prevent noble structure, with follow up to confirm remission of the lesion.

A conservative treatment of an involved molar tooth associated with dentigerous cyst: a case report and literature review

BackgroundDentigerous cysts (DCs) are among the most frequently odontogenic cysts in young and middle-aged individuals. Marsupialization and enucleation are the main treatment options in clinical practice. However, there are few reports on preserving molars severely involved by the cyst.Case presentationA 35-year-old male patient with a large odontogenic cyst that was successfully treated using a multidisciplinary approach. The patient’s chief complaint was discomfort during mastication in the lower left molar region for a month. Clinical examination revealed that teeth 36 and 37 were intact without pain upon percussion, while tooth 38 was unerupted. The radiology examination illustrated a typical well-defined oval radiolucent lesion surrounding the crown of unerupted tooth 38, extending to the distal root of tooth 37. The treatment was divided into two parts: removal of the cyst and the impacted third molar, followed by filling with collagen bone particles; and preserving the tooth 37 via hemisection, root canal treatment and crown restoration. Pathological examination indicated a dentigerous cyst. After 18 months of treatment, the bone defect completely recovered and tooth 37 functioned well following the hemisection.ConclusionsHemisection effectively preserves the cyst-associated molars and maintains oral function. This article underscores the significance of collaboration among various departments in the treatment of odontogenic cysts, ultimately aiming to achieve minimally invasive and functional surgery.