This research Influence Previewing Predicting Strategy and Reading Motivation toward Students' Reading Comprehension. Quantitative research was carried out using Pre-test, Post-test, and Questionnaire. Data analysis used the Independent t-Test and Two-Ways Anova. The appropriate research material uses descriptive text. The population in the research was class VII students of Junior High School 10 Palembang. Meanwhile, the research sample was 70 students taken using a simple random sampling technique and divided into two groups, namely experimental and control, totaling thirty-five students who had high reading motivation and thirty-five students who had low reading motivation. Data collection uses an instrument in the form of a Multiple choice written test which has four alternative answers regarding students' reading abilities. The difficulty that students experience in learning English in class is not being able to understand English texts. Previewing Predicting Strategies need to be implemented in English classes to overcome students' difficulties in understanding English texts. The results of this study indicate that there is an interaction effect of the Previewing Predicting Strategy and Reading Motivation toward students' Reading Comprehension. This means that the null hypothesis (Ha) is rejected and the alternative hypothesis (Ho) is accepted. The conclusion shows that Previewing Predicting Strategy and Reading Motivation show a significant role in increasing students' Reading Comprehension in Descriptive Text.