BackgroundAccurate measurement of linear energy transfer (LET) is crucial in medical physics, particularly for proton therapy dosimetry. High atomic-number (Zeff) materials such as BaFBr and low-Zeff materials such as Al2O3 and water are commonly used in dosimeters. PurposeTo evaluate the feasibility and accuracy of the use of various dosimetry materials (water, air, Al2O3, aluminum (Al), BaFBr, and oxygen) for measuring LET by comparing their stopping power (ratios) via the Bethe-Bloch theory and semiempirical models. MethodsStopping power ratios were calculated via the PSTAR database for proton energies ranging from 0.01 MeV to 10,000 MeV. The Bethe-Bloch theory with density and shell corrections was used for high-energy protons, whereas a semiempirical model was applied for low-energy protons. Calculations validation involved comparing the computed stopping powers SRIM-2008 and PSTAR for materials such as water, aluminum, air, Al2O3, BaFBr, and oxygen. ResultsThe stopping power water-to-air ratio remains stable, while the Al2O3-to-water and air-to-water ratios highlight their differing attenuation properties. The BaFBr-to-water ratio shows significant material-dependent differences, and the water-to-Al2O3 ratio is particularly relevant for proton therapy dosimetry calculations in medical physics. These results demonstrate consistency across materials but do not inherently confirm the accuracy of LET measurements. However, a comparison of theoretical models with computed stopping powers SRIM-2008 and PSTAR showed strong agreement, particularly for high-energy protons where the Bethe-Bloch theory was applied, suggesting that the models reliably predict stopping power at these energy levels. ConclusionsThis study confirms the feasibility of using high-Zeff materials such as BaFBr and low-Zeff materials such as Al2O3 and water for the use of LET measurements in proton therapy. The results validate the use of the Bethe-Bloch theory, computed stopping powers and semiempirical models in dosimetric applications, enhancing the precision of LET measurements and contributing to improved radiation therapy outcomes.
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