Low Pressure Research Articles

Double-step hydroforming mechanism of metal bipolar plates for hydrogen fuel cells

ABSTRACT Bipolar plate (BPP) is a key component affecting the efficiency and economy of hydrogen fuel cell, and multi-stage forming process is an effective method to improve the forming quality of metal BPP. In this thesis, a double-step hydroforming model of BPP with a serpentine flow field is established and numerical simulation is used to study the influence of die geometry and process parameters on the forming quality of BPP. The results show that the double-step hydroforming process is superior to the conventional hydroforming. The higher the forming pressure, the better the quality of the BPP, but it will result in severe local thinning; both high and low pre-forming pressures result in lower forming quality; rib fillet have less effect on forming results; the larger the flow channel fillet radius, the more uniform the forming thickness of the plate, and a noticeable second thinning area will appear at the corner when the radius is less than 0.2 mm; the draft angle and the ratio of the flow channel width have a minor impact on the double-step hydroforming effect; the thinner the plate thickness, the easier the forming, but it is prone to rupture during the forming process.

Size-Effect Enriched Phase Diagram in p-Type Skutterudite Superconductor Ir3.8Sb12.

Pressurized Ir4X12 (X = P and As) stands out as the sole p-type superconductors among dozens of filled-skutterudites that are primarily characterized by n-type charge carriers. The emergence of superconductivity is proposed to be intimately related to the inharmonic rattling phonons originating from the filled atoms. Here, we explore the impact of the size effect of the rattling atoms by substituting X with Sb, whose radius is 30 and 17% larger than those of P and As, respectively. In situ synchrotron X-ray diffractions reveal a similar structural evolution of self-inserted Sb atoms inside the Sb11 cage but at a significantly lower critical pressure of 33.6 GPa. Interestingly, single crystalline Ir3.8Sb12 exhibits a more diverse electronic phase diagram compared to its P- and As-based counterparts, encompassing an anomalous resistance upturn, a complete superconducting dome, and a filled-semiconducting region. We propose that the intrinsic deficiency of Ir and the filling ratio of central atoms, both stemming from the size effect of Sb, are responsible for the observed rich phenomena.

Room Temperature Ethene to Propene (ETP) Tandem Catalysis using Single Crystalline Solid-State Molecular Pre-Catalysts.

A tandem catalytic ensemble of solid-state molecular organometallic (SMOM) crystalline pre-catalysts are deployed under batch or flow conditions for the ethene to propene process (ETP). These catalysts operate at ambient temperature and low pressure, via sequential ethene dimerization, butenes isomerization and cross-metathesis. Under flow conditions the on-stream ethene conversion (55%), initial propene selectivity (92%), stability (71% selectivity after 7 hrs) and low temperature/pressures are competitive with the best-in-class heterogenous systems, marking a new,in crystallo, approach to ETP.

Attachment of Hydrogel Patches to Eye Tissue through Gel Transfer using Flexible Foils.

Glaucoma, a leading cause of blindness, demands innovative and effective treatments that surpass the limitations of current drug and surgical interventions to lower intraocular pressure. This study describes the generation of cell-repellent hydrogel patches, their deposition on the ocular surface, and a photoinduced chemical binding between the patches and the collagens of the eye. The hydrophilic and protein-repellent hydrogel patch is composed of a copolymer made from dimethylacrylamide and a comonomer unit with anthraquinone moieties. A thin layer of the prepolymer is deposited on a flexible foil. This foil has a hydrophobic side on top and superhydrophilic sides on the bottom. A small amount of added water can penetrate easily through the foil and release the polymer, which is thus transferred from the foil onto the eye at the desired location. Through brief irradiation with UV light with a wavelength of 365 nm, the prepolymer is simultaneously cross-linked and covalently attached to the eye's surface through C-H insertion reactions. We describe the handling, attachment, UV irradiation effects on nearby healthy tissues, biocompatibility, stability, and cellular interaction of the patches during in vitro studies.

Waveform characteristics in thoracic paravertebral space: a prospective observational study

Background With increased use of thoracic paravertebral block (TPVB) in thoracic surgery, many faced the challenge of locating the thoracic paravertebral space (TPVS) ultrasonographically. This observational study aimed to investigate the waveform characteristics and pressure value within the TPVS in anaesthetized patients with controlled ventilation. Methods 50 patients scheduled for elective lung surgery were enrolled. After conduction of anesthesia, all patients underwent TPVB at T4/5 and T6/7 using transverse, in-plane ultrasound guidance. A pressure transducer system with a desktop monitor was connected to the needle hub to measure pressure values and waveform characteristics in three locations: the paraspinal muscles, immediately behind the superior costotransverse ligament, and within the TPVS. Next, 15 mL of 0.33% bupivacaine was injected into each desired TPVS. After completion of the surgery, the extent of dermatomal blockade and the pain score was assessed in all patients. Results 98 typical regular respiratory waveforms with a mean pressure of ≤ 25 mmHg were detected in the TPVS of 50 patients. The sensitivity of the combined ultrasound and pressure waveform measurement technique to identify the TPVS was 95.45% (95% confidence interval, 84.527–99.445). Nontypical respiratory waveforms were present in two patients. Factors interfering with the TPVS waveform characteristics were previous thoracic surgery. Conclusion The TPVS had low pressure and showed a smooth, regular waveform pattern corresponding to respiration.

Ligustrazine hydrochloride Prevents Ferroptosis by Activating the NRF2 Signaling Pathway in a High-Altitude Cerebral Edema Rat Model

High-altitude cerebral edema (HACE) is a disorder caused by low pressure and hypoxia at high altitudes. Nevertheless, as of now, there is still a scarcity of safe and effective prevention and treatment methods. The active component of Ligusticum Chuanxiong, namely Ligustrazine hydrochloride (LH), has shown potential in the prevention and treatment of HACE due to its anti-inflammatory, antioxidant, and neuroprotective effects in nervous system disorders. Consequently, the potential protective effect of LH on HACE and its mechanism still need to be further explored. Prior to modeling, 90 male Sprague-Dawley rats were pretreated with different doses of drugs, including LH (100 mg/kg and 50 mg/kg), dexamethasone (4 mg/kg), and ML385 (30 mg/kg). Subsequently, the pretreated rats were placed in a low-pressure anoxic chamber simulating a plateau environment to establish the rat HACE model. The effects and mechanisms of LH on HACE rats were further elucidated through determination of brain water content, HE staining, ELISA, immunofluorescence, molecular docking, molecular dynamics simulation, western blot, and other techniques. The results showed, first of all, that LH pretreatment can effectively reduce brain water content; down-regulate the expression of AQP4, HIF-1α, and VEGF proteins; and alleviate damage to brain tissue and nerve cells. Secondly, compared with the HACE group, LH pretreatment can significantly reduce MDA levels and increase GSH and SOD levels. Additionally, LH decreased the levels of inflammatory factors IL-1β, IL-6, and TNF-α; reduced total iron content in brain tissue; increased the expression of ferroptosis-related proteins such as SLC7A11, GPX4, and FTH1; and alleviated ferroptosis occurrence. Molecular docking and molecular dynamics simulations show that LH has a strong binding affinity for NRF2 signaling. Western blot analysis further confirmed that LH promotes the translocation of NRF2 from the cytoplasm to the nucleus and activates the NRF2 signaling pathway to exert an antioxidant effect. The NRF2 inhibitor ML385 can reverse the anti-oxidative stress effect of LH and its protective effect on HACE rat brain tissue. In summary, LH may have a protective effect on HACE rats by activating the NRF2 signaling pathway, inhibiting ferroptosis, and resisting oxidative stress.

Closing the Circulation Budget

AbstractCirculation budgets can identify physical processes underpinning tropical cyclones, mesoscale convective vortices, and other weather systems where there are interactions across scales. It is unclear, however, how well these budgets close in practice. The present study uses the rapid intensification of Tropical Cyclone Nepartak (2016) as a case study to quantify the practical limitations of calculating circulation budgets using standard reanalyzes and numerical weather model data. First, we evaluate the circulation budget with ERA5. The budget residual can be reduced considerably by including contributions to circulation changes from subgrid‐scale momentum transports, and reduced further with 24‐hr smoothing, which dampens the discontinuous effects of data assimilation. Second, using a high‐resolution Met Office Unified Model simulation, we examine how the choice of the path used (the domain boundary) affects the budget closure. Third, the truncation errors associated with numerical differentiation in time and space are investigated. The circulation budget improves as the model data are analyzed with more frequent time output intervals, and as the output grid spacing decreases. For the tropical convective examples evaluated here, the column mean budget residuals increase by up to 50% as the output intervals increase from 5 min to 3 hr. Errors also increase if the data are regridded to a coarser horizontal grid spacing and when convection straddles the domain boundary. A key result is that the circulation budget need not close for physical inferences made about the circulation and its evolution to be meaningful, thus validating the use of the technique in prior studies.

Carbonyl Reductase 1: a novel regulator of blood pressure in Down Syndrome.

Approximately one in every 800 children is born with the severe aneuploid condition of Down Syndrome, a trisomy of chromosome 21. Low blood pressure (hypotension) is a common condition associated with DS and can have a significant impact on exercise tolerance and quality of life. Little is known about the factors driving this hypotensive phenotype and therefore therapeutic interventions are limited. Carbonyl reductase 1 (CBR1) is an enzyme contributing to the metabolism of prostaglandins, glucocorticoids, reactive oxygen species and neurotransmitters, encoded by a gene (CBR1) positioned on chromosome 21 with the potential to impact blood pressure. Utilising telemetric blood pressure measurement of genetically modified mice, we tested the hypothesis that CBR1 influences blood pressure and that its overexpression contributes to hypotension in Down Syndrome by evaluating possible contributing mechanisms in vitro. In a mouse model of Down Syndrome (Ts65Dn), which exhibits hypotension, CBR1 activity was increased and pharmacological inhibition of CBR1 increased blood pressure. Mice heterozygous null for Cbr1 had reduced CBR1 enzyme activity and elevated blood pressure. Further experiments indicate that the underlying mechanisms include alterations in sympathetic tone and prostaglandin metabolism. We conclude that CBR1 activity contributes to blood pressure homeostasis and inhibition of CBR1 may present a novel therapeutic opportunity to correct symptomatic hypotension in Down Syndrome.

Manufacturability and Performance Study of Triply Periodic Minimal Surface Air-to-Air Heat Exchanger

Abstract The study tests 3D printability, heat transfer characteristics and pressure drop of two types of triply periodic minimal surface heat exchanger in order to develop new flow principles for compact heat exchanger design. Various generic plate heat exchanger designs are also tested to compare to the printed alternatives. Geometry variations for heat exchangers and laboratory testing air recuperators are modelled in SolidWorks software and manufactured mostly by UV LCD and FDM additive manufacturing methods. Digital light processing printing method has been found to be most successful in printing the TPMS structures, while using photopolymer materials. Literature studies conclude that the most promising structures are Schoen’s gyroid and Schwarz-diamond surfaces, which have been modelled and tested in several variations. Using these results, full size gyroid and Schwarz-D structure heat exchangers have been modelled, manufactured and tested. The results are compared and analysed to study the effect of advanced surface designs in heat transfer efficiency. The obtained results can be used in compact air-to-air thermal recuperator development as well as other low pressure heat exchanger applications, as the printed TPME heat exchangers outperform the plate heat exchangers in similar dimensions.

Photoacoustics for Direct Light‐Guiding Inside Transparent and Scattering Media

AbstractThe rapid and precise delivery of light at targeted positions on a sample is essential for any light‐based application, including laser materials processing or imaging. However, current systems for light control rely on bulky and costly optical components placed outside the sample. This configuration can be limited by the sample's geometry, poor flexibility in the illumination, and shallow penetration depth, particularly for scattering samples. Here a novel approach is proposed for guiding light within optically transparent and scattering media while obviating any external components. By simply employing an absorptive material and a pulsed laser, this method leverages the photoacoustic generation of a localized pressure wave to induce refractive index gradients within a medium. These gradients act as non‐invasive optical waveguides, that allow for light focusing and guiding across several millimeters at sub‐microsecond time scales. The principle and implementation of this method are described, the light‐guiding effects through various tissue phantoms are simulated and measured, and micrometric laser marking of a photo‐absorbing layer is demonstrated inside a 7‐mm‐thick scattering phantom. The possibility to operate with endogenous absorbing materials and low pressures makes photoacoustic‐enabled light guiding a promising step toward rapid light delivery at conditions not feasible today.

Tailored Cathode Composite Microstructure Enables Long Cycle Life at Low Pressure for All-Solid-State Batteries

Tailored Cathode Composite Microstructure Enables Long Cycle Life at Low Pressure for All-Solid-State Batteries

Laminated Two-Terminal All-Perovskite Tandem Solar Cells with Transparent Conductive Adhesives.

Established sequential deposition of multilayer two-terminal (2T) all-perovskite tandem solar cells possesses challenges for fabrication and limits the choice of materials and device architecture. In response, this work represents a lamination process based on a transparent and conductive adhesive that interconnects the wide-bandgap (WBG) perovskite top solar cell and the narrow-bandgap (NBG) perovskite bottom solar cell in a monolithic 2T all-perovskite tandem solar cell. The transparent conductive adhesive (TCA) layer combines Ag-coated poly(methyl methacrylate) microspheres with an optical adhesive. The TCA is employed as a recombination junction, achieving self-encapsulation with high transparency and good conductivity. A high vertical electrical conductivity is realized by optimizing the distribution of microspheres using a novel solidification strategy that employs UV curing and drying at 85 °C at low pressure. In addition, uniform and dense bilayer hole transport layers are realized by vapor-phase evaporation, which facilitates the application of the TCA and achieves pinhole-free buried interfaces in both the WBG perovskite top solar cell and the NBG perovskite bottom solar cell. Using these two strategies, losses in fill factor (FF) and open-circuit voltage (VOC) of the 2T all-perovskite tandem solar cell are reduced, achieving a respectable power conversion efficiency up to 18.2% for the lamination of the all-perovskite tandem solar cell. The laminated tandem solar cell retains ∼93% of initial efficiency after exposure in ambient air (30-70 RH% and 20-35 °C) for ∼30 days.

Influence of large-scale atmospheric circulation and Mediterranean sea surface temperature to extreme land precipitation: the case of storm Alex

Abstract Extreme (greater than 500 mm) amount of rain fell in southeastern France and northern Italy on 2nd and 3rd October 2020 during a "Mediterranean episode" triggered by the powerful extratropical cyclone Alex. Here we use a dynamical adjustment methodology based on constructed analogues to assess the contributions of different drivers to the magnitude of this extreme precipitation event. We first show that the mean effect of the observed atmospheric circulation pattern, an intense low-pressure system centered over the coasts of Western Europe associated with a cold pool and a secondary low-pressure system, can explain about 80 percent of the precipitation event magnitude. By contrasting the effect of Alex atmospheric circulation with an anomalously warm Mediterranean sea and eastern Atlantic ocean versus neutral sea surface temperature conditions, we show that the influence of September 2020 positive sea surface temperature anomalies can explain a large fraction of the 20 percent residual precipitation over southeastern France and northern Italy. Finally, based on a storyline approach, we find that the dynamic component, the atmospheric circulation contribution to the extreme precipitation event, was more extreme than it would have been, had it occurred during the mid-20th century. The increase in the magnitude of the dynamic component since 1950 follows a Clausius-Clapeyron scaling, in agreement with previous studies about the intensity changes of Mediterranean extreme precipitation episodes. (limit =300 words)

Neonatal Shock: Current Dilemmas and Future Research Avenues

Neonatal shock presents a complex clinical challenge and is one of the leading causes of mortality. Traditionally, neonatal shock is equated to hypotension, and therapeutics are often initiated based on low blood pressure (BP) values alone. This fails to address the underlying goal of optimizing the tissue perfusion resulting in both over- and under-treatment of neonatal shock. Also, what defines a normal BP in neonates is still a contentious topic. Further, the most appropriate way of measuring BP in neonates with shock is still debated. Shock secondary to transient circulatory instability and patent ductus arteriosus, conditions that are unique to preterm neonates, have not been researched adequately. Treatment of myocardial dysfunction secondary to perinatal asphyxia, a leading cause of neonatal mortality, is still a conundrum. Quite similarly, there are only a handful of controlled trials evaluating therapeutics in some of the other commonly encountered conditions, namely, septic shock and hypoperfusion secondary to pulmonary hypertension. Even the universally practiced intervention of volume expansion with crystalloid boluses in shock is not backed by high-certainty evidence in neonates. Though the diagnostic modalities of functional echocardiography and near-infrared spectroscopy have aided greatly in the management of neonatal shock in recent years, these have not been proven to be associated with improved critical clinical outcomes such as mortality and major brain injury. To conclude, neonatologists often rely on limited evidence, mostly anecdotal, when treating neonatal shock. This review critically examines the current evidence with respect to various aspects of neonatal shock with an objective to identify the lacunae in the literature that may fuel future research, eventually paving the way to efficacious, safe and evidence-based clinical practice.

A randomized sequential cross-over trial evaluating five purportedly ICP-lowering drugs in idiopathic intracranial hypertension.

To gain initial insight into the efficacy to lower intracranial pressure (ICP), side effects, and effects on cognition of five drugs commonly used to treat idiopathic intracranial hypertension (IIH). Limited clinical data exist for the treatment for IIH. Impaired cognition is recognized in IIH and can be exacerbated by medications. This human experimental medicine study was a secondary analysis that focused on an unblinded randomized, sequential, cross-over extension of a previously completed randomized controlled trial. This study evaluated females with active IIH, recruited from University Hospital Birmingham, UK. Participants were treated, in randomized order, for 2 weeks with acetazolamide, amiloride, furosemide, spironolactone, and topiramate; assessment was at baseline and 2 weeks with a minimum 1-week drug washout between drugs. The primary outcome was change in ICP at 2 weeks post-drug administration. The cognitive evaluation was an exploratory study of the trial. ICP was recorded with telemetric, intraparenchymal ICP monitors (Raumedic, Hembrechts, Germany). Adverse events were recorded, and cognition was assessed utilizing the National Institutes of Health Toolbox Cognitive Battery. Fourteen participants were recruited and evaluated by intention-to-treat analysis. Mean (standard deviation) body mass index was 37.3 (7.0) kg/m2 and ICP was 33.2 (7.1) cm cerebrospinal fluid (CSF) at baseline. ICP fell with four drugs (mean [standard error (SE)]), acetazolamide -3.3 (1.0) mmHg, p = 0.001, furosemide -3.0 (0.9) mmHg, p = 0.001, spironolactone -2.7 (0.9) mmHg, p = 0.003, and topiramate -2.3 (0.9) mmHg, p = 0.010. There was no significant difference between drugs. Side effects were common with acetazolamide (100%, 11/11) and topiramate (93%, 13/14). Baseline cognitive performance was impaired, T-score (mean [SE]) 37.2 (2.6). After treatment, there was a further significant reduction in the fluid cognition domain (ability to process and integrate) with acetazolamide (mean T-score [SE]), -5.0 (2.6), p = 0.057 and topiramate -4.1 (2.0), p = 0.061. Acetazolamide, furosemide, spironolactone, and topiramate marginally reduced ICP. While their effects were not significant, this study was not powered to detect a difference between drugs. Participants reported significant side effects with acetazolamide and topiramate including cognitive decline. Cognitive measures were impaired by acetazolamide and topiramate. Therapeutics with greater efficacy and a favorable side effect profile are an unmet need in the treatment of IIH.

A Review of Ignition Characteristics and Prediction Model of Combustor Under High-Altitude Conditions

High-altitude relight is a critical challenge for aero-engines, directly impacting the safety and emergency response capabilities of aircraft. This paper systematically reviews the physical mechanisms, key factors, and relevant prediction models of high-altitude relight, highlighting the detrimental effects of extreme conditions such as low pressure and temperature on fuel evaporation rates, flame propagation speeds, and turbulent combustion processes. A comprehensive overview of the current state of high-altitude relight research is presented, alongside recommendations for enhancing the ignition performance of aero-engines under extreme conditions. This paper focuses on the development of ignition prediction models, including early empirical and semi-empirical models, as well as physics-based models for turbulent flame propagation and flame kernel tracking, assessing their applicability in high-altitude relight scenarios. Although flame kernel tracking has shown satisfactory performance in predicting ignition probability, it still overly relies on manually set parameters and lacks precise descriptions of the physical processes of flame kernel generation. Future studies on some topics, including refining flame kernel modeling, strengthening the integration of experimental data and numerical simulations, and exploring the incorporation of new ignition technologies, are needed, to further improve model reliability and predictive capability.

Determination of the Electric Field by Particle Tracking in a Plasma Sheath Region during Free Fall

In this work we present an experiment in which we injected microspheres at low pressure into a capacitively coupled argon plasma chamber. The setup was located in the top point of the Einstein-Elevator drop tower in Hannover, Germany, where the microparticles reached their equilibrium position above the lower electrode during 1g. During the fall, the trajectories of the microparticles, which were driven by the electric force, the neutral drag force and some residual gravitational force, were recorded. In addition, simulations of the plasma conditions were performed with commercial software to determine the microparticle charges via an orbital motion limit theory approach, taking into account the charge exchange in ion-neutral collisions. Based on the calculated position dependence of the microparticle charges and the electric force, the electric field present in the plasma sheath region was finally determined.

Synthesis and Assessment of Metal-Organic Frameworks (MOFs) Adsorbents for CO2 Capture: A Comparative work of the CO2 Adsorption Capability of Mono- and Bimetal-based MOFs Adsorbents

Adsorption utilising porous solid adsorbent has been considered a feasible option for conventional CO2 absorption over the past few decades. As a preliminary investigation towards obtaining Metal-Organic Frameworks (MOFs) adsorbent for CO2 capture, the CO2 adsorption efficiency using mono- and bimetal-based MOFs was assessed in this study. Among the numerous MOFs, Mg-MOF-74 exhibits the best CO2 uptake at low pressures because of its open metal sites. A strategy to incorporate Zn in Mg-based MOF as a co-metal node is required to enhance the CO2 adsorption performance of solid adsorbent. Selecting Zn as a metal node in MOF synthesis allows for the creation of stable, versatile, and functional materials for CO2 adsorption. Therefore, combining several metals in a structure to develop a new MOF with an improved gas uptake is quite a useful approach to further harness the immense potential of MOFs. This study aims to compare the performance of mono- and bimetallic-MOFs and select the most suitable adsorbent for CO2 capture. The performance of CO2 adsorption was conducted using three parameters: the effect of metal loading on MOFs, pressure (1–5 bar) and adsorbent dosage (0.2–0.5g). Based on the characterisation findings, the studies confirm the formation of Mg-MOF-74, Zn-MOF and 50wt.%Zn/50wt.%Mg-MOF. Overall, it was found that the bimetal adsorbent with 50 wt.%Zn/50wt.%Mg-MOF displayed the highest CO2 adsorption capacity (323 mgCO2/gadsorbent) when compared to the monometallic MOFs (Zn-MOF (134mgCO2/gadsorbent) and Mg-MOF-74) (122 mgCO2/gadsorbent) indicating a 50% increase in adsorption capacity over monometallic MOFs.

Dynamic Failure Mechanism and Fractal Features of Fractured Rocks Under Quasi-Triaxial Static Pressures and Repeated Impact Loading

Mastering the dynamic mechanical behaviors of pre-stressed fractured rocks under repeated impact loads is crucial for safety management in rock engineering. To achieve this, repeated impact loading experiments were performed on produced fractured samples exposed to varying pre-applied axial and confining pressures using a split Hopkinson pressure bar test system in combination with a nuclear magnetic resonance imaging system, and the dynamic failure mechanism and fractal features were investigated. The results indicate that the dynamic stress–strain curves exemplify typical class II curves, and the strain rebound progressively diminishes with growing impact times. The impact times, axial pressure, and confining pressure all significantly affect the dynamic peak strength, average dynamic strength, dynamic deformation modulus, average dynamic deformation modulus, maximum strain, and impact resistance performance. Moreover, under low confining pressures, numerous shear cracks and tensile cracks develop, which are interconnected and converge to form large-scale macroscopic fracture surfaces. In contrast, specimens under a high confining pressure primarily experience tensile failure, accompanied by localized small-scale shear failure. Under low axial pressure, some shear cracks and tensile cracks emerge, while at high axial pressure, anti-wing cracks and secondary coplanar cracks occur, characterized predominantly by shear failure. In addition, as the confining pressure grows from 8 to 20 MPa, the fractal dimensions are 2.44, 2.32, 2.23, and 2.12, respectively. When the axial pressures are 8, 14, and 20 MPa, the fractal dimensions are 2.44, 2.46, and 2.52, respectively. Overall, the degree of fragmentation of the sample decreases with growing confining pressure and grows with rising axial pressure.

Fructose-Modified Chitosan/Gelatin 3D Composite Sponge for Enhanced Rapid Hemostasis.

Managing uncontrolled and noncompressible bleeding presents a major challenge in emergency trauma care. Methods to halt bleeding quickly and efficiently, without applying direct pressure on the wound, have become a key focus of research. Herein, a novel fructose-modified chitosan/gelatin composite sponge has been developed, exhibiting high elasticity, low rebound pressure, and excellent cell compatibility. This material can rapidly return to its original form in around 1.5 s after being compressed by 80% upon contact with water. Additionally, experimental results from a rat liver wound model demonstrated that it exhibited a clear hemostatic effect. The hemostatic time was shortened from 204 ± 15.35 s to 53.3 ± 6.54 s, and the blood loss was reduced from 867 ± 153.15 mg to 187 ± 61.06 mg. Moreover, it can promote tissue healing by inhibiting the production of inflammatory factors including TNF-α, MCP-1, and IL-6. This material offers an effective solution for noncompressible tissue injuries.