In low-permeability sandstone reservoirs (LPSR), impermeable interlayers significantly challenge carbon capture, utilization, and storage (CCUS) and enhance oil recovery (CO2-EOR) processes by creating complex, discontinuous flow units. This study aims to address these challenges through a comprehensive multi-faceted approach integrating geological and microscopic analyses, including core analysis, reservoir petrography, field emission-scanning electron microscopy (FE-SEM), energy dispersive spectroscopy (EDS), and well-logging response analysis, and utilizing three-dimensional (3D) geological modeling. The current comprehensive investigation systematically characterizes interlayer types, petrophysical properties, thickness, connectivity, and their spatial distribution in the reservoir unit. Numerical simulations were conducted to assess the sealing efficiency and the impact of various interlayer materials on CO2 flooding over a 10-year period. Results indicate the presence of petrophysical and argillaceous interlayers, with optimal sealing occurring in petrophysical barriers ≥ 4 m and argillaceous barriers ≥ 1.5 m thick. CO2 leakage occurs through preferential pathways that emerge in a side-to-middle and bottom-to-top direction in interbeds, with multidirectional pathways showing greater leakage at the bottom compared to the upper side within barriers. Increased interlayer thickness constraints CO2 breakthrough but reduces vertical flooding area and production ratio compared to homogeneous reservoirs. Augmented interbed thickness and area mitigate CO2 breakthrough time while constraining gravity override and dispersion effects, enhancing horizontal oil displacement. These novel findings provide crucial insights for optimizing CCUS-EOR strategies in LPSR, offering a robust theoretical foundation for future applications and serving as a key reference for CO2 utilization in challenging geological settings of LPSR worldwide.
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