Introduction. Heat insulation of multi-story buildings with a reinforced concrete frame on pile foundations under climatic conditions with extremely low outdoor air temperatures is complicated by high air infiltration. When such buildings are used in winter, the most characteristic are temperature regime violations on the first floor. Purpose of the study: The study aimed to evaluate various methods to reduce the influence of thermal bridges in the basement floor of a cast-in-situ frame building with pile foundations under extreme climatic conditions. Methods: Thermal performance of 3D models of enclosing structures was determined using the certified HEAT3 program. Options of internal and external heat insulation of the basement floor with thermal breaks in the structures were considered. Results: As a result of numerical analysis of standard basement floor designs, it was established that low temperature on the inner surface and significant heat losses are associated with the presence of through thermal bridges: reinforced concrete raft — basement slab — column — concrete block masonry. The most effective solution for heat insulation of cast-in-situ frame buildings is external heat insulation of the basement floor with a thermal break in the raft. Compared to the standard solution, heat losses through the corner section of the slab with the offset column are reduced by 33.6 %, and the minimum temperature on the inner surface is higher than the dew point.