Lower Moderate-to-vigorous Physical Activity Research Articles

Adopting the "Exercise as a Vital Sign" metric to assess physical activity in GI oncology patients.

650 Background: Regular moderate to vigorous physical activity (MVPA) in patients with gastrointestinal (GI) cancers is associated with improved health outcomes, including greater quality of life and reduced fatigue and comorbidity. PA guidelines for cancer survivors recommend ≥150 minutes of MVPA per week for optimal health. Identifying GI oncology patients with low MVPA is important to tailor interventions aimed at increasing MVPA levels in this population. The “Exercise as a Vital Sign” (EVS) tool is a validated, two question assessment tool to quantify minutes per week (min/wk) of MVPA that was incorporated in the clinical rooming process at an academic GI oncology clinic. Here, we report characteristics of patients by amount of MVPA by EVS. Methods: Patient information was entered in the electronic medical record at a large, academic oncology clinic. Data from the first clinic visit where min/wk of MVPA EVS was collected were extracted and included demographics (e.g. age, sex, marital status, race), health status (body mass index (BMI), Eastern Cooperative Oncology Group (ECOG) performance status, comorbidities), cancer characteristics (primary tumor site, localized/metastatic, current treatment), and reason for the clinic visit. MVPA was divided into two groups based on the recommended guidelines: 0-149 min/wk (“low”) and ≥150 min/wk (“high”). Chi-square and t-tests were used to examine statistically significant differences. Results: Among 265 patients abstracted, EVS data were reported from 156 (59%) patients. Mean (standard deviation (SD)) age was 61 (13) years (range: 25-82). The primary cancer site was 35% colorectal, 23% pancreatic, 17% gastroesophageal, 10% neuroendocrine, and 15% other GI cancers. While gastroesophageal cancer patients reported high amounts of MVPA (mean (SD) = 268 (309) min/wk), comparisons with other cancer sites were not statistically different. Of the 156 with EVS data, 84 (54%) had low MVPA (mean (SD): 55 (49) min/wk) and 72 (46%) had high MVPA (mean (SD): 357 (244) min/wk). Demographic and cancer characteristics were similar across the two groups. Patients with high MVPA were more likely to have BMI 18.5-24.9 kg/m2 (56% vs. 31%) and less likely to have BMI ≥25 kg/m2 (40% vs.61%) compared to patients with low MVPA (p = 0.02). Patients with high vs. low MVPA were also more likely to have excellent performance status (ECOG 0; 47% vs. 24%, p < 0.001). Conclusions: In this study, GI oncology patients not meeting PA guidelines for cancer survivors were more likely to be overweight/obese and have worse performance status. The EVS tool was an inexpensive and accessible measure of MVPA that can be used to identify patients with low MVPA for interventions targeted to improve health outcomes. A lack of statistical significance may be due to low power. At the conference, more data will be presented (̃1000 patient visits), including longitudinal data and MVPA by active chemotherapy regimen.

Sedentary And Physical Activity Patterns In Children With Intellectual Disabilities: Differences Between Levels Of Intellectual Disability

PURPOSE: To analyze the potential severity difference of children with intellectual disabilities in sedentary patterns and physical activity (PA) levels. METHODS: A cross-sectional descriptive study was completed by 153 children with mild to severe ID (mild ID = 48, moderate ID =60, severe ID = 45) aged 8.0 to 14.0 years. Children wore an ActiGraph GT3+ accelerometer over a consecutive 7 days to assess minutes per day of sedentary time (ST), light physical activity (LPA) and moderate to vigorous physical activity (MVPA). A valid day was defined as recording at 8 hours of measured wear time between 7:00 am and 20:00 pm and non-wear time was defined as >60 min of consecutive zeros from Boddy’ s finding. The intensity cutoffs of the measured PA levels are as follows: LPA (<2,800 count per min (CPM)), MVPA (>4000 CPM) recommended for this population. Multivariate analysis of covariance (MANCOVA) was used to compare the ST and PA levels between different level of ID. RESULTS: Controlling for participants gender, age and BMI. ID level was significantly associated with ST, LPA and MVPA among children with ID, Pillai’s λ = 0.53, F(6,290) = 18.379, η2 = 0.28, p < 0.01. Children with severe ID (711.06 ± 28.84 min/day) had significantly longer ST than those with moderate ID (699.86 ± 123.94 min/day) and those with mild ID (642.64 ± 26.77 min/day). Children with severe ID (60.18 ± 22.18 min/day) had significantly lower LPA than those with moderate ID (76.59 ± 25.82 min/day) and those with mild ID (108.05 ± 26.54 min/day). Children with severe ID (20.75 ± 6.98 min/day) had significantly lower MVPA than those with moderate ID (38.55 ± 17.14 min/day) and those with mild ID (43.95 ± 14.70 min/day). CONCLUSIONS: ST, LPA and MVPA differ significantly among children with different levels of ID, with severer ID level had longer ST and lower PA levels. These findings suggest that population specific interventions are critical to promote physical activity levels and improve health in children with different levels of ID.

A Longitudinal Study on Associations of Moderate-to-Vigorous Physical Activity With Plasma Monounsaturated Fatty Acids in Pregnant Women

ObjectivesMaternal physical activity (PA) may influence pregnant women and offspring health via its impact on fatty acids metabolism. This study aimed to examine associations of PA with plasma phospholipid monounsaturated fatty acids (MUFAs) during pregnancy. MethodsThe study included 321 pregnant women from the NICHD Fetal Growth Studies (N = 2802) with plasma phospholipid MUFAs and PA measured four times at 10–14, 15–26, 23–31, and 33–39 gestational weeks (GWs). Leisure time moderate-to-vigorous PA (MVPA) was analyzed as both continuous (hour/week) and binary variables (i.e., high MVPA: ≥150 min/week vs. low MVPA: <150 min/week). Associations of MVPA with 7 individual plasma phospholipid MUFAs were assessed at each visit using multivariable linear regression models adjusting for age, race, education, marriage status, nulliparous, gestational diabetes, pre-pregnancy body mass index and Alternative Health Eating Index score. Weights were applied to reflect the entire cohort. Bonferroni-corrected P value < 0.05 was considered as statistically significant. ResultsMVPA (hour/week) was positively associated with plasma palmitoleic acid (β = 0.02, P < 0.001; N = 206) at 23–31 GW, and oleic acid (β = 0.08, P = 0.003; N = 308) at 15–26 GW. Meanwhile, compared to women with low level of MVPA, women with high level of MVPA had higher palmitoleic acid at 10–14 (β = 0.07, P = 0.001; N = 318) GW and 23–31 (β = 0.15, P < 0.001; N = 206) GW, and higher oleic acid (β = 0.40, P = 0.001; N = 308) at 15–26 GW. ConclusionsWe found positive associations of maternal MVPA with plasma palmitoleic acid and oleic acid at second trimester. Our findings are novel and worthy of further studies to confirm whether leisure time PA is a modifiable factor for MUFAs metabolism during pregnancy. Funding SourcesEunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)/National Institutes of Health (NIH); internal funding from University of California Los Angeles (UCLA).

Longitudinal Associations of Sedentary Behavior and Physical Activity with Quality of Life in Colorectal Cancer Survivors.

Given the growing population of colorectal cancer (CRC) survivors, identifying ways to enhance health-related quality of life (HRQoL) and alleviate complaints of fatigue and chemotherapy-induced peripheral neuropathy (CIPN) is essential. We aimed to assess longitudinal associations of sedentary behavior (SB) and moderate to vigorous physical activity (MVPA) independently, as well as their joint association, with HRQoL, fatigue, and CIPN in CRC survivors. In a prospective cohort among stage I-stage III CRC survivors (n = 396), five repeated home visits from diagnosis up to 24 months posttreatment were executed. SB was measured using triaxial accelerometers, and MVPA, HRQoL, fatigue, and CIPN were measured by validated questionnaires. We applied confounder-adjusted linear mixed models to analyze longitudinal associations from 6 wk until 24 months posttreatment. Average time in prolonged SB (accumulated in bouts of duration ≥30 min) was 5.3 ± 2.7 h·d-1, and approximately 82% of survivors were classified as sufficiently active (≥150 min·wk-1 of MVPA) at 6 wk posttreatment. Decreases in SB and increases in MVPA were independently associated with better HRQoL and less fatigue over time. No associations were found for CIPN complaints. A synergistic interaction was observed between prolonged SB and MVPA in affecting functioning scales. Relative to CRC survivors with low prolonged SB and high MVPA, survivors with high prolonged SB and low MVPA reported a stronger decrease in physical functioning and role functioning over time than expected based on the independent associations of prolonged SB and MVPA. Our longitudinal results show that less SB and more MVPA are beneficial for CRC survivors' HRQoL and fatigue levels. Our findings regarding interaction underscore that joint recommendations to avoid prolonged sitting and accumulate MVPA are important.

Physical Activity, Screen Time, and Sleep Trajectories From Childhood to Adolescence: The Influence of Sex and Body Weight Status.

Behavioral trajectories from childhood to adolescence may differ and are poorly understood. The authors estimated the trajectories of moderate to vigorous physical activity (MVPA), screen time, and sleep duration during this period, by sex and initial weight status. Data from Quebec Adiposity and Lifestyle Investigation in Youth, an ongoing cohort study in Canada on the natural history of obesity, were used. Participants predisposed to obesity attended baseline (8-10 y old, n = 630) and follow-up visits 2 years (n = 564) and 7 years (n = 359) after baseline. Participants with completed self-reported and accelerometer-based data were included in the analyses (n = 191, 353, and 240 for MVPA, screen time, and sleep, respectively). The authors performed group-based trajectory analyses and multinomial logistic regression models. Two MVPA, 3 screen time, and 2 sleep trajectories were identified. Girls were more likely than boys to belong to trajectory with lower MVPA means (odds ratio [OR] = 6.45; 95% confidence interval [CI],3.08 to 13.49), yet less likely to belong to the trajectory with higher screen time (OR = 0.47; 95% CI, 0.23 to 0.97) and lower sleep duration (OR = 0.46; 95% CI, 0.27 to 0.78). Overweight or obesity at baseline was associated with a greater likelihood of belonging to the trajectory with lower MVPA (OR = 10.99; 95% CI, 1.31 to 91.14) and higher screen time (OR = 2.01; 95% CI, 1.04 to 4.06), respectively. It appears to be gender- and weight-based determinants of behavioral trajectories in this sample. These results may provide guidance for interventions in similar populations.

Changes in Sitting Time, Screen Exposure and Physical Activity during COVID-19 Lockdown in South American Adults: A Cross-Sectional Study.

The worldwide prevalence of insufficient physical activity (PA) and prolonged sedentary behavior (SB) were high before the coronavirus (COVID-19) pandemic. Measures that were taken by governments (such as home confinement) to control the spread of COVID-19 may have affected levels of PA and SB. This cross-sectional study among South American adults during the first months of COVID-19 aims to (i) compare sitting time (ST), screen exposure, moderate PA (MPA), vigorous PA (VPA), and moderate-to-vigorous PA (MVPA) before and during lockdown to sociodemographic correlates and (ii) to assess the impact of lockdown on combinations of groups reporting meeting/not-meeting PA recommendations and engaging/not-engaging excessive ST (≥7 h/day). Bivariate associations, effect sizes, and multivariable linear regressions were used. Adults from Argentina (n = 575) and Chile (n = 730) completed an online survey with questions regarding demographics, lifestyle factors, and chronic diseases. Mean reductions of 42.7 and 22.0 min./day were shown in MPA and VPA, respectively; while increases of 212.4 and 164.3 min./day were observed in screen and ST, respectively. Those who met PA recommendations and spent <7 h/day of ST experienced greatest changes, reporting greater than 3 h/day higher ST and more than 1.5 h/day lower MVPA. Findings from the present study suggest that efforts to promote PA to South American adults during and after COVID-19 restrictions are needed.

Profiles of Loneliness and Social Isolation in Physically Active and Inactive Older Adults in Rural England.

Objective: Loneliness and social isolation are associated with higher risk of morbidity and mortality and physical inactivity in older age. This study explored the socioecological context in which both physically active and inactive older adults experience loneliness and/or social isolation in a UK rural setting. Design: A mixed-methods design employed semi structured interviews and accelerometer-measured moderate-to-vigorous physical activity (MVPA). Interviews explored the personal, social and environmental factors influencing engagement with physical activities, guided by an adapted-socioecological model of physical activity behaviour. Findings: Twenty-four older adults (Mean Age = 73 (5.8 SD); 12 women) were interviewed. Transcripts were thematically analysed and seven profiles of physical activity, social isolation and loneliness were identified. The high-MVPA group had established PA habits, reported several sources of social contact and evaluated their physical environment as activity friendly. The low MVPA group had diverse experiences of past engagement in social activities. Similar to the high MVPA, they reported a range of sources of social contact but they did not perceive the physical environment as activity friendly. Conclusions: Loneliness and/or social isolation was reported by both physically active and inactive older adults. There is wide diversity and complexity in types and intensity of PA, loneliness and social isolation profiles and personal, social and environmental contexts.

Asthma and Physical Activity in Urban Children.

Asthma and obesity disproportionately affect urban minority children. Avoidance of physical activity contributes to obesity, and urban children with asthma are at risk for lower levels of physical activity. We examined associations between lung function and moderate to vigorous physical activity (MVPA) and moderators of this association in a diverse sample of children with asthma. Urban children (N = 142) ages 7-9 with persistent asthma and their caregivers completed a study of asthma and physical activity. Longitudinal mixed effects models examining daily-level asthma and physical activity evaluated the association between asthma and MVPA, and the moderating effect of weight, and cultural/contextual factors on this association. Average daily MVPA was below recommended guidelines. Differences in MVPA were found by racial/ethnic group (p = .04) and weight (p = .001). Poorer asthma status was associated with lower MVPA in Latino and Black participants (p's < .05), and in normal weight youth (p = .01). Body mass index (BMI) moderated the association between asthma and MVPA. Those with lower BMI had more optimal asthma status and higher MVPA levels, whereas associations attenuated for participants with higher BMI (p = .04). Caregivers' perceptions of neighborhood safety and fear of asthma were marginally associated with children's symptoms and MVPA: as perceptions of safety decreased and fear increased, associations between asthma and MVPA weakened (p's = .09 and .07, respectively). Suboptimal asthma status is associated with less MVPA in urban children. Weight status and cultural/contextual factors play a role in the association and are worthy targets for future research and intervention.

Parental control and support for physical activity predict adolescents\u2019 moderate to vigorous physical activity over five years

BackgroundSocial factors are important determinants of youth physical activity (PA), but the longitudinal association between parental behaviours and adolescent PA has not been clearly assessed. This prospective study examined average and lagged associations between perceived parental support and control with adolescents’ moderate to vigorous PA (MVPA); and assessed the independent associations between specific parental support and control behaviours and adolescents’ MVPA.MethodsData from three cycles of the MATCH study, when 374 participants were 12, 16 and 17 years old, were included in this analysis. At each cycle, participants self-reported questionnaires on perceived tangible parental support, intangible support, and control behaviours as well as number of days per week attaining at least 60 min of MVPA. Mixed effect models were used to assess the longitudinal relationship between parental behaviours and MVPA. Cross-lagged panel design was used to assess the association of parental behaviours during early adolescence with MVPA during late adolescence.ResultsOverall parental support (coef. = 0.46, P < 0.0001), tangible support (coef. = 0.37, P < 0.0001), encouragement (coef. = 0.12, P = 0.025) and transportation (coef. = 0.25, P < 0.0001) were positively associated with MVPA, whereas parental control was a negative predictor of MVPA (coef. = − 0.18, P = 0.003). Perceived parental behaviours appeared to have long term associations (5 y.) with MVPA as parent support (coef. = 0.40, P = 0.006) and co-participation (coef. = 0.33, P = 0.017) reported around age 12 were positively associated with MVPA measured 5 years later.ConclusionsParental support for PA, particularly in the form of tangible support, may be a key factor to include in interventions aiming to promote PA during adolescence. In contrast, parents should be encouraged to avoid control behaviours as these appear to lead to lower MVPA among adolescents.

Momentary associations between stress and physical activity among children using ecological momentary assessment

Chronic and acute stress may have a detrimental effect on children's physical activity. Research on stress as a predictor of children's physical activity has mostly focused on stress between children, rather than how children's within-day variation in stress may predict physical activity. The current study assessed the within- and between-effects of stress on subsequent physical activity in three different time windows using ecological momentary assessment (EMA) and accelerometry. Children (N = 190; MBaseline Age = 10.1 ± 0.9, 53% female, 56% self-identified Hispanic/Latino) completed six semi-annual assessment bursts across three years. During each burst, participants responded to up to seven (weekend) or three (weekday) randomly prompted EMA surveys on smartphones for seven days and wore a waist-worn accelerometer. Multi-level structural equation modeling examined within- and between-subjects effects of stress as a predictor of children's subsequent moderate-to-vigorous physical activity (MVPA) in the 15, 30, and 60 min following the EMA prompt. Latent variables were created for within- and between-subjects stress were comprised of three EMA stress items. Higher than average levels of stress (within-subjects) significantly predicted lower MVPA in the subsequent 15, 30 and 60 min (ps < .05). Between-subjects stress was not significantly associated with subsequent MVPA (ps > .05). Results indicate that elevated momentary stress predicts less subsequent MVPA. These findings suggest that within-day fluctuations in stress may be a barrier for children engaging in physical activity. Childhood physical activity promotion and interventions should consider the role of children's stress, aim to reduce the stress children experience throughout the day, and incorporate stress coping strategies.

Associations of Sleep With Sedentary Behavior and Physical Activity Patterns Across Pregnancy Trimesters.

Sleep, sedentary behavior, and moderate-to-vigorous physical activity (MVPA) are altered in pregnancy and may affect pregnancy health; however, how these behaviors are associated with each other is unclear. Pregnant women (N=120) completed the Pittsburgh Sleep Quality Index and wore an activPAL3 micro and ActiGraph GT3X for 7days in each trimester to assess sleep, sedentary behavior, and MVPA, respectively. Latent trajectories described patterns of sleep duration, efficiency, and quality as well as sedentary behavior and MVPA. Multinomial logistic regression examined associations of sleep patterns with sedentary behavior and MVPA patterns and, in exploratory analyses, with adverse pregnancy outcomes. Trajectories were identified for sleep duration (consistently short, 20.7% of sample; consistently adequate, 79.3%), efficiency (consistently low, 17.5%; consistently high, 82.5%), and quality (consistently poor, 15.1%; worsening, 23.5%; and consistently good, 61.5%). Compared with those in more optimal sleep groups, women in the short duration, low efficiency, and worsening quality groups had lower odds of being in the moderate and/or high sedentary behavior group (odds ratio range, 0.21-0.31; 95% confidence interval range, 0.09-0.65). Women in the worsening quality group had greater odds of being in the low MVPA group (odds ratio, 2.51; 95% confidence interval, 1.18-5.38). Trends were observed with women in less optimal sleep groups having greater odds of adverse pregnancy outcomes and lower odds of excessive gestational weight gain. Less optimal sleep patterns in pregnancy are associated with less sedentary behavior and MVPA; additional research is needed to confirm associations between sleep and pregnancy outcomes.

Correlates of Objectively Measured Sleep and Physical Activity Among Latinx 3-To-5-Year Old Children

PurposeLatinx children have the highest prevalence of obesity in the US. Physical activity (PA) and sleep are important risk factors for this health disparity, yet limited evidence exists examining objectively measured data among this population. We aim to identify correlates of sleep and PA, as well as the association between sleep and PA, among a sample of Latinx children. Design and methodsA cross-sectional study was conducted with thirty Latinx 3-to-5-year old children who wore GT3X+ triaxial accelerometers for five consecutive days, from which we examined sleep and PA constructs. Linear regression and ANOVA were used to examine study constructs. ResultsSedentary behavior, light PA, and MVPA (moderate-to-vigorous PA) were 51.7, 5.6, and 2.6 min/h respectively. Total sleep duration averaged 9.6 h, sleep efficiency averaged 80.0%, and sleep variability averaged 1.30 h/night. Higher household income was associated with sleep variability (F = 7.240, p = .012) and lower sedentary behavior (F = 5.481, p = .027), and higher sleepiness was associated with lower MVPA (β = −0.503, p = .005) and higher child BMI (β = 0.531, p = .033). MVPA was associated with higher sleep efficiency (β = 0.441, p = .016). ConclusionsHousehold income emerged as a correlate of sleep variability and sedentary behavior in our study. In addition, we found that MVPA levels were associated with sleep efficiency. Practice implicationsOur results signal an impetus for further research (particularly with larger, multi-site study designs) examining study constructs among Latinx children.

Adolescent movement behaviour profiles are associated with indicators of mental wellbeing

Recent work has demonstrated the collective impact of daily movement behaviours on mental health outcomes, however, positive aspects of mental health have received much less attention. The purpose of this study was to identify unique adolescent movement behaviour profiles and determine whether profile membership is associated with differences in mental wellbeing. This study used data from the baseline assessment of the ADAPT study. A total of 1166 Canadian adolescents enrolled in grade 11 classes (Mage = 15.91 ± 0.48; 54% female) self-reported their movement behaviours – moderate-to-vigorous physical activity (MVPA), recreational screen time (ST) and sleep – and completed three measures of mental wellbeing: flourishing, self-esteem and resiliency. Latent profile analysis with distal outcomes comparisons were conducted. Four distinct profiles were identified: one healthy profile (high MVPA/low ST), two mixed behavioural profiles (low MVPA/low ST and high MVPA/high ST), and one profile considered to be the least healthy (low MVPA and high ST). Sleep patterns were similar across the profiles. The healthiest profile was consistently associated with better mental wellbeing, followed by the mixed behaviour profiles, and the least healthy profile had the poorest scores for mental wellbeing. These findings highlight the additive benefits of engaging in a full complement of healthy movement behaviours. Moving forward, behavioural interventionists should consider adopting an integrated approach to promoting mental wellbeing through targeting each of the movement behaviours concurrently.

Correlates of dual trajectories of physical activity and sedentary time in youth: The UP & DOWN longitudinal study.

Trajectories of physical activity and sedentary time (SED) may differ between subgroups of youth. The aim of this study was to identify group-based dual trajectories of physical activity and SED and explore individual, social, and environmental correlates of these trajectories. Longitudinal data (three time points, baseline 2011-2012) of Spanish youth (n=1597, mean age=11.94±2.52, 50.9% boys) were used. Moderate-to-vigorous physical activity (MVPA) and SED were assessed objectively at each time point, and 21 potential correlates were self-reported at baseline. Parallel process growth mixture models identified shared categorical latent groups, adjusting for school and age. Multinomial logistic regression models identified baseline correlates of a given trajectory. Four shared categorical latent groups were identified: (1) stable MVPA and decreasing SED (4%); (2) stable MVPA and increasing SED (3%); (3) consistently higher MVPA (18%); and (4) stable low MVPA and slight increase in SED (75%). Multinomial logistic regression models with group 3 as reference found: negative affect (RRR=0.90, 95% CI 0.84-0.97), parental screen-time rules (RRR=1.15, 95% CI 1.00-1.33), and household media equipment (RRR=1.17, 95% CI 1.05-1.30) predicted likelihood of group 1 membership; cons of reducing SED (RRR=2.70, 95% CI 1.77-4.10) predicted likelihood of group 2 membership; and co-participation in physical activity with friends (RRR=0.80, 95% CI 0.69-0.94), fathers' modeling of TV viewing (RRR=1.22, 95% CI 1.02-1.47), and household media equipment (RRR=1.16, 95% CI 1.02-1.31) predicted likelihood of group 4 membership. Results suggest that strategies to improve MVPA and SED behaviors among youth may need to be multifaceted, targeting all levels of influence.

Differences in objectively measured daily physical activity patterns related to depressive symptoms in community dwelling women - mPED trial.

Physical activity (PA) is an effective depression treatment. However, knowledge on how variation in day-to-day PA relates to depression in women is lacking. The purposes of this study were to 1) compare overall objectively measured baseline daily steps and duration of moderate to vigorous PA (MVPA) and 2) examine differences in steps and MVPA on days of the week between women aged 25–65 years, who were physically inactive, with high and low depressive symptoms, enrolled in a run-in period of the mobile phone based physical activity education (mPED) trial. The Center for Epidemiological Studies Depression Scale was used to categorize low/high depressive symptom groups. We used linear mixed-effects models to examine the associations between steps and MVPA and depression-status overall and by day of the week, adjusting for selected demographic variables and their interactions with day of the week. 274 women were included in the final analysis, of which 58 had high depressive symptoms. Overall physical activity levels did not differ. However, day of the week modified the associations of depression with MVPA (p = 0.015) and daily steps (p = 0.08). Women with high depression were characterized by reduced activity at the end of the week (Posthoc: Friday: 791 fewer steps, 95% CI: 73–1509, p = 0.03; 8.8 lower MVPA, 95% CI: 2.16–15.5, p = 0.0098) compared to women with low depression, who showed increased activity. Day of the week might be an important target for personalization of physical activity interventions. Future work should evaluate potential causes of daily activity alterations in depression in women.

Age-varying Bi-directional Associations Between Momentary Affect and Movement Behaviors in Children: Evidence From a Multi-wave Ecological Momentary Assessment Study.

The bi-directional associations between affective states and movement behaviors (e.g., physical activity, sedentary behavior) have been observed in children. It is unclear if the strength of these bi-directional associations varies with age as children transition from childhood to adolescence. This multi-wave ecological momentary assessment (EMA) study investigates the acute time-varying associations between affect and movement behaviors among youth. Children (N = 195, baseline mean age = 10.72, range = 8-12 years, mean BMI-z = 0.49, 51% female) participated in a six-wave EMA study across three years. Each EMA survey captured momentary positive and negative affect. Time spent in moderate-to-vigorous physical activity (MVPA) and sedentary time in the 15-min window before and after each EMA survey was calculated using accelerometry data. Time-varying effect models (TVEM) examined the acute bi-directional associations between momentary positive/negative affect and MVPA/sedentary time across ages 8 to 14. Children provided 14,246 valid activity-matched EMA surveys across all waves. TVEM plots revealed that the directionality and the strength (time-varying slopes) of associations between momentary affect and activity levels vary across ages. Positive affect was associated with higher MVPA levels and lower sedentary time at younger ages, whereas negative affect linked to lower MVPA levels and more sedentary time at older ages. The acute associations between momentary affect and (in)activity levels may vary as a function of children's age. Applying TVEM to intensive longitudinal data could provide valuable information for developing age-tailored interventions that promote healthy lifestyles among children and adolescents.

Sedentary patterns are associated with BDNF in patients with type 2 diabetes mellitus.

Exercise is beneficial to type-2 diabetes-mellitus (T2DM), and there is evidence showing that one of those benefits include a higher expression of brain-derived neurotrophic factor (BDNF), which has been implicated in improving fat oxidation and cognitive development. The deleterious effect of prolonged sedentary time (ST) on BDNF levels has never been examined in patients with T2DM. Our goal was to analyse the associations for sedentary patterns [i.e. breaks in ST per sedentary hour (BST-ST) and bouts of sedentary time (BSB) of different length] with BDNF in patients with T2DM, independent of moderate-to-vigorous physical activity (MVPA) and cardiorespiratory fitness (CRF). Sample included 80 patients (38 women) with T2DM (58.3 ± 7.8years). ST and MVPA were assessed by accelerometry (ActiGraph, GT3X + model), BDNF by blood collection and plasma quantification using commercial enzyme-linked immunosorbent assay kits, and CRF was determined using a Bruce protocol to exhaustion, on a motorized treadmill. Positive associations for BST-ST (β = 0.155; p = 0.007) with BDNF, and negative associations for BSB longer than 15min with BDNF were found (β = -0.118; p = 0.049). Neither MVPA nor cardiorespiratory fitness eliminated the associations for BST-ST with BDNF, but MVPA eradicated the associations between BSB > 15min and BDNF. Our findings suggest that interrupting ST and especially avoiding longer sedentary periods (> 15min) may be beneficial for BDNF plasma abundance that may influence metabolic and cognitive functioning of patients with T2DM, especially for the ones presenting lower MVPA levels. May 5, 2017, ClinicalTrials.govID:NCT03144505.

Changes in Physical Activity Patterns from Childhood to Adolescence: Genobox Longitudinal Study.

Longitudinal changes of physical activity (PA) from childhood into adolescence have not been accurately described yet for the Spanish population. The aim of this study is to evaluate the changes of PA, assessed by accelerometry and anthropometric measures in a cohort of 213 children from the prepubertal to pubertal period, focusing on those with valid data from both time points (n = 75). Sedentary time (ST) increased about 50%, while all PA intensities declined from the pre-pubertal to pubertal period. Light PA (LPA) was the major contributor, decreasing by about 30%. Boys were more active than girls in both periods, but they showed a higher decline in PA, especially moderate-to-vigorous PA (MVPA). The proportion who reached the recommendation of 60 min of MVPA decreased by 33.3% in boys and 4.6% in girls. Children with obesity or overweight had lower MVPA than those with normal-weight in the pre-pubertal period, but no differences were found in the pubertal period. This study shows a decrease of PA and an increase of sedentarism in the transition from childhood to adolescence, particularly in boys. Regardless of body weight, adolescents tend to be less active. Therefore, prevention programs should be implemented to achieve optimal PA and reduce sedentarism during infancy considering the differences found by sex.

Cross-sectional associations of device-measured sedentary behaviour and physical activity with cardio-metabolic health in the 1970 British Cohort Study.

This study aimed to examine the cross-sectional associations of thigh accelerometry-assessed sedentary behaviour and moderate-to-vigorous physical activity (MVPA) with cardio-metabolic health markers and prevalent diabetes in a population sample of middle-aged British adults. Participants (n=4892) from the age-46-to-48 wave of the 1970 British Cohort Study were fitted with a waterproofed activPAL3 micro device. Total/prolonged sedentary time, breaks and MVPA were the main exposures. We dichotomized prolonged sedentary time and MVPA based on the corresponding median, generating four combinations as categorical exposures. Outcomes comprised of diabetes and seven cardio-metabolic health markers. We used logistic regression and generalized linear models to examine independent/joint associations, conducting a minimally adjusted model including demographics and contextual covariates, and further adjusted for total sedentary time and/or MVPA as applicable. Each set of 10 sedentary breaks and 1h of prolonged sedentary time were associated with HbA1c (mmol/mol) [B=-0.18 (-0.33, -0.03) and 2.35 (1.01, 3.69), respectively]. Each set of 10 sedentary breaks and 1h of MVPA were favourably associated with diabetes [adjusted odds ratio (AOR): 0.80 (0.71, 0.99) and 0.42 (0.26, 0.67), respectively]. Joint analyses showed that only the low MVPA × long sedentary time combination had significantly higher odds for diabetes than the referent high MVPA × short sedentary time combination [AOR: 1.89 (1.17, 3.03)]. Each set of additional 10 sedentary breaks per day was associated with 20% lower odds for diabetes. A low physical activity level combined with long sedentary time might synergistically deteriorate cardio-metabolic health.

Tai Chi practice and change in exercise habits in survivors of acute coronary syndromes: Is mindfulness a possible mechanism?

BackgroundMechanisms by which mind-body practice may improve exercise behaviors in patients with coronary heart disease (CHD) are unknown. PurposeTo identify predictors of exercise behaviors developed in response to a tai chi intervention. MethodsWe conducted an exploratory analysis using data from a pilot study of tai chi for physically inactive patients with CHD. We used Latent Class Analysis to identify patterns of moderate to vigorous physical activity (MVPA) (accelerometry-assessed, average min/week) over the 9-month study period. Logistic regression was used to evaluate associations between MVPA patterns and changes in exercise self-efficacy (Self-efficacy for exercise scale), social support (Multidimensional Scale of Perceived Social Support), resilience (Brief Resilience Survey), and mindfulness (Five Facets of Mindfulness) at 6 months. ResultsData supported a 3-class model over time: 31% of participants were in class 1 (high and sustained MVPA, > 200 min/week), 21% were in class 2 (low and decreasing MVPA, < 100 > 50 min/week), and 48% in class 3 (low and stable MVPA, < 50 min/week). Higher mindfulness scores at 6 months were associated with a high and sustained MVPA pattern (b = 1.89, SE = 0.15, p = .01). Social support was inversely associated with low and decreasing MVPA (b = -0.72, SE = 0.34, p = .04). No associations were noted with the other factors. ConclusionsImprovements in mindfulness were associated with a distinct high and sustained MVPA pattern. Although only hypothesis-generating, these findings suggest that improvements in mindfulness skills could be a mechanism for the possible effect of Tai Chi in the promotion of MVPA.