New insights on geochemistry of the alkaline volcanism of Ngaoundere in Adamawa plateau enable the petrogenesis modelling of Ngaoundere Miocene lava series. Mass-balance crystal fractionation, closed-system Assimilation, Fractional Crystallization (AFC) and partial melting rate modeling attempted for Ngaoundere volcanism are re-examined. Inductively Couple Plasma-Mass Spectrometry (ICP-MS) and Inductively Couple Plasma Atomic Emission Spectroscopy (ICP-AES) analyses show that lavas are microlitic porphyritic textures. Decrease of major element (MgO, Fe 2 O 3 , TiO 2 , CaO) with increasing SiO 2 contents results from fractionation of olivine, clinopyroxene and Fe-Ti-oxides in the parental basaltic magma. Similarly, for felsic magma, decrease in Al 2 O 3 , Na 2 O and K 2 O contents depends upon feldspar fractionation and decrease in P 2 O 5 from apatite fractionation, thus underline a typical feature of alkaline basaltic lavas of Ngaoundere volcanism. The results evidence the differentiation by fractional crystallization process. Parental magmas of Ngaoundere volcanism have undergone a low partial melting rate (2 to 3 %) of the heterogeneous mantle source. © 2016 International Formulae Group. All rights reserved. Keywords: Major and trace elements, fractional crystallization, partial melting, modeling, Ngaoundere volcanism, Adamawa plateau