Conventional pulse-and-glide (PnG) strategies expose issues including poor coordination with energy management systems (EMSs), discomfort and low levels of automation, this paper innovatively addresses these challenges by the comprehensive considerations of energy economy, dynamic performance, and ride comfort, proposing an intelligent pulse-and-glide (I-PnG) strategy tailored for plug-in hybrid electric vehicle (PHEV) configurations. The I-PnG strategy is aimed at optimizing economic cruising in high-speed scenarios; however, it demonstrates applicability across diverse conditions without deterioration in performance. I-PnG is a data-driven autonomous driving solution developed through a deep Q network (DQN), featuring two distinct modes: ECO and SPORT, the former prioritizes energy economy, while the latter emphasizes dynamic performance enhancement. The results indicate that our proposed strategy significantly optimizes energy management compared to the baseline methods. Specifically, during variable-speed cruising, I-PnG ECO achieves a maximum energy efficiency improvement of 16.13 % and a cost reduction of 7.74 %, while I-PnG SPORT exhibits a maximum energy efficiency improvement of 13.37 % and a cost reduction of 3.92 %. Under the Highway Fuel Economy Test (HWFET), I-PnG ECO and I-PnG SPORT further improve energy efficiency by up to 22.94 % and 19.04 %, respectively, with corresponding cost savings of 18.47 % and 13.35 %.