Low Exercise Research Articles

Affective, perceptual and physiologic responses to isokinetic contractions under blood flow restriction.

Blood flow restriction (BFR) has been shown to enhance the effectiveness of low load resistance exercise, but less research has examined its utility in conjunction with maximal isokinetic contractions, which may depend on the restrictive pressure and speed of contraction. Individuals reported to the laboratory for three visits to complete three sets of 20 maximal elbow flexion exercises at 60°/s and 300°/s under 0%, 40% and 80% of their arterial occlusion pressure. Muscle thickness was measured before and after exercise, and ratings of discomfort, perceived activation, and exercise-induced feelings were obtained at the completion of each exercise. Fatigue was assessed as the decline in average peak torque across the three sets. A total of 27 individuals (11 females, 16 males) completed the study. There was a significant interaction for torque at both 60°/s and 300°/s (P<0.001), with each increasing pressure resulting in greater fatigue. Muscle swelling was present across all conditions but was lowest in the 40% BFR condition applied during the 300°/s speed. At both 60°/s and 300°/s speeds, the 80% BFR pressure was associated with lower enjoyment, greater discomfort, and greater perceived activation (all P<0.05). The combined effects of BFR to maximal isokinetic contractions increased fatigue with less of an impact on muscle swelling. These results indicate that BFR may enhance the effectiveness of long-term isokinetic training, but it is also important to consider the addition of BFR was associated with lower levels of enjoyment and greater discomfort which may decrease adherence.

Coingestion of Collagen With Whey Protein Prevents Postexercise Decline in Plasma Glycine Availability in Recreationally Active Men.

Whey protein ingestion during recovery from exercise increases myofibrillar but not muscle connective protein synthesis rates. It has been speculated that whey protein does not provide sufficient glycine to maximize postexercise muscle connective protein synthesis rates. In the present study, we assessed the impact of coingesting different amounts of collagen with whey protein as a nutritional strategy to increase plasma glycine availability during recovery from exercise. In a randomized, double-blind, crossover design, 14 recreationally active men (age: 26 ± 5years; body mass index: 23.8 ± 2.1kg·m-2) ingested in total 30g protein, provided as whey protein with 0g (WHEY), 5g (WC05); 10g (WC10), and 15g (WC15) of collagen protein immediately after a single bout of resistance exercise. Blood samples were collected frequently over 6hr of postexercise recovery to assess postprandial plasma amino acid kinetics and availability. Protein ingestion strongly increased plasma amino acid concentrations (p < .001) with no differences in plasma total amino acid availability between treatments (p > .05). The postprandial rise in plasma leucine and essential amino acid availability was greater in WHEY compared with the WC10 and WC15 treatments (p < .05). Plasma glycine and nonessential amino acid concentrations declined following whey protein ingestion but increased following collagen coingestion (p < .05). Postprandial plasma glycine availability averaged -8.9 ± 5.8, 9.2 ± 3.7, 23.1 ± 6.5, and 39.8 ± 11.0mmol·360min/L in WHEY, WC05, WC10, and WC15, respectively (incremental area under curve values, p < .05). Coingestion of a small amount of collagen (5g) with whey protein (25g) is sufficient to prevent the decline in plasma glycine availability during recovery from lower body resistance-type exercise in recreationally active men.

Reliability, validity, usefulness, and sensitivity of a submaximal test of performing burpees in 3 minutes, in assessing and detecting changes in aerobic fitness of athletes during future prolonged self-isolation in a confined environment.

During a prolonged quarantine, there is a need to monitor aerobic fitness levels of trained individuals who are isolated with a simple fitness test that can be performed in confined space of their own homes. This study examined the reliability, validity, usefulness and sensitivity of a novel 3-min submaximal heart rate burpees test (or Sub<inf>HR</inf>3-MBT) to assess and monitor changes in aerobic fitness, of trained athletes. In the Sub<inf>HR</inf>3-MBT, male and female athletes performed 48 and 39 burpees respectively, within 3 min by following a constant beeping pace. The performance criterion of the Sub<inf>HR</inf>3-MBT is the highest heart rate attained (or exercise HR<inf>peak</inf>) at the end of 3-min (wherein a lower exercise HR<inf>peak</inf> indicates a higher level of aerobic fitness). A total of 40 male and female national athletes from various sports volunteered for the study. For reliability (Part 1), the Sub<inf>HR</inf>3-MBT showed good relative and excellent reliability, with intraclass correlation coefficient 0.90 and coefficient of variation 2.6%, respectively. For validity (Part II), there was significant negative correlation between relative exercise HR<inf>peak</inf> with respiratory gas-measured VO<inf>2max</inf> (r=-0.51, large; P<0.001). The test's technical error of measurement of 2.3 is slightly greater than its smallest worthwhile change of 1.5. For sensitivity (Part III), the athletes were tested twice for their Sub<inf>HR</inf>3-MBT and VO<inf>2max</inf>, once at baseline and another at a followed-up test after >10 weeks. There was a significant correlation between the % change in relative exercise HR<inf>peak</inf> with the % change in VO<inf>2max</inf> (r=-0.66, large; P<0.001). The Sub<inf>HR</inf>3-MBT is a reliable, valid, marginally useful test and may be able to track changes in aerobic fitness in trained athletes with moderate levels of sensitivity, in case of future isolation due to pandemic occurrence.

Effectiveness of Adding Lower Extremity Isotonic Exercise on Hamstring Flexibility of Hajj Pilgrims Who Receive Walking Aerobic Exercise

Effectiveness of Adding Lower Extremity Isotonic Exercise on Hamstring Flexibility of Hajj Pilgrims Who Receive Walking Aerobic Exercise

Decreased postpartum exercise capacity after a diagnosis of pre-eclampsia: Implications for CVD risk prediction

BackgroundHypertensive disorders of pregnancy (HDP) are associated with increased long-term risk for cardiometabolic risk factors (chronic hypertension [HTN], obesity, diabetes) and heart failure. Exercise capacity is a known predictor of heart failure in patients with normal resting cardiac filling pressures. In this prospective observational cohort study, we sought to identify predictors of reduced postpartum exercise capacity in participants with normotensive vs. preeclamptic pregnancies. MethodsPreeclampsia (PreE) and normotensive subjects were enrolled to undergo bedside echocardiography within 48 hours of delivery, and rest/exercise echocardiography 12 weeks postpartum. ResultsRecruited subjects (n=68) were grouped according to their blood pressure as: a) normotensive pregnancy n=15; b) PreE with normotensive postpartum (PreE-Resolved, n=36); c) PreE with persistent postpartum HTN (PreE-HTN, n=17). At enrollment, a significantly higher percentage of subjects in the PreE-HTN group were Black. Compared to normotensive and PreE-Resolved subjects, those with PreE-HTN demonstrated higher resting systolic blood pressure (SBP, 112 [normotensive] vs 112 [PreE-Resolved] vs 134 [PreE-HTN], p<0.001) and diastolic blood pressure (DBP, 70.0 vs 72.5 vs 85.0, p<0.001), and significantly less postpartum weight loss (9.6% vs 13.6% vs 3.8%, p<0.001). Following Bruce protocol stress testing, PreE-HTN subjects demonstrated achieved significantly lower exercise duration (10.4 vs 10.2 vs 7.9 minutes, p = 0.001). Subjects with PreE-HTN also demonstrated evidence of exercise-induced diastolic dysfunction as assessed by peak exercise lateral e’ (18.0 vs 18.0 vs 13.5, p=0.045) and peak exercise tricuspid regurgitation velocity (TR Vm, 2.4 vs 3.0 vs 3.1, p = 0.045). Exercise duration was negatively associated with gravidity (R=-0.27, p=0.029) and postpartum LV mass index (R=-0.45, p<0.001), resting average E/e’ (R=-0.51, p<0.001), BMI (R=-0.6, p<0.001) and resting SBP (R=-0.51, p<0.001). ConclusionsPostpartum exercise stress testing capacity is related to readily available clinical markers including pregnancy factors, echocardiographic parameters and unresolved cardiometabolic risk factors.

Self-Generated Lower Body Negative Pressure Exercise: A Low Power Countermeasure for Acute Space Missions.

Microgravity in spaceflight produces headward fluid shifts which probably contribute to Spaceflight-Associated Neuro-Ocular Syndrome (SANS). Developing new methods to mitigate these shifts is crucial for preventing SANS. One possible strategy is the use of self-generated lower body negative pressure (LBNP). This study evaluates biological or physiological effects induced by bed rest to simulate adaptations to microgravity. Participants were tested during powered LBNP and dynamic self-generated (SELF) LBNP at 25 mmHg for 15 min. The results were compared to the physiologic responses observed in seated upright and supine positions without LBNP, which served as controls for normal gravitational effects on fluid dynamics. Eleven participants' (five male, six female) heart rates, blood pressures, and cross-sectional areas (CSA) of left and right internal jugular veins (IJV) were monitored. Self-generated LBNP, which requires mild to moderate physical activity, significantly elevated heart rate and blood pressure (p < 0.01). Self-generated LBNP also significantly reduced right IJV CSA compared to supine position (p = 0.005), though changes on the left side were not significant (p = 0.365). While the effects of SELF and traditional LBNP on IJV CSA were largely similar, traditional LBNP significantly reduced IJV CSA on both sides. Given its low mass, volume, and power requirements, SELF LBNP is a promising countermeasure against SANS. Results from this study warrant longer-term studies of SELF LBNP under simulated spaceflight conditions.

Effects of upper limb low resistance exercises along with manual lymphatic drainage in subjects with post radical mastectomy – a pilot study

Introduction: Post radical mastectomy patients will have physical problems like reduced shoulder movements and upper limb muscles strength. The performance and overall function of upper limb and Quality of Life (QOL) will reduce followed by these muscle’s reduced activity. The aim of present study is to find the effects of manual lymphatic drainage with low resistance training of upper limb on shoulder function and QOL of post mastectomy patients. Generally, upper limb muscles like Trapezius, serratus anterior, pectoralis s group. 1 subject from experimental group withdrawal from study. The treatment duration is 12 weeks based on cancer Rehabilitation principle. Outcome measures are taken Lymph ICF (for QOL), anatomical circumferential measurements (for Lymphedema). Patients selected based on the inclusion and exclusion criteria. Experimental group patients receiving upper limb low resistance training and manual lymphatic drainage techniques and control group patients receiving only manual lymphatic drainage techniques. Both group of patients are advised to wear upper limb elastic stockings for 8 hours per day. Result: All Outcome measures taken in baseline (pre) and end of 12 weeks (post) in both groups. Data was analysed by using paired ’t’ test. Results analysed based on pre and post test values. Conclusion: The study has designed a structured low resistance upper limb exercise program for post radical mastectomy patients in improving shoulder function and QOL.

The effects of habitual resistance exercise training on cerebrovascular responses to lower body dynamic resistance exercise: A cross-sectional study.

Dynamic resistance exercise (RE) produces sinusoidal fluctuations in blood pressure with simultaneous fluctuations in middle cerebral artery blood velocity (MCAv). Some evidence indicates that RE may alter cerebrovascular function. This study aimed to examine the effects of habitual RE training on the within-RE cerebrovascular responses. RE-trained (n=15, Female=4) and healthy untrained individuals (n=15, Female=12) completed four sets of 10 paced repetitions (15 repetitions per minute) of unilateral leg extension exercise at 60% of predicted 1 repetition maximum. Beat-to-beat blood pressure, MCAv and end-tidal carbon dioxide were measured throughout. Zenith, nadir and zenith-to-nadir difference in mean arterial blood pressure (MAP) and mean MCAv (MCAvmean) for each repetition were averaged across each set. Two-way ANOVA was used to analyse dependent variables (training × sets), Bonferroni corrected t-tests were used for post hoc pairwise comparisons. Group age (26±7 trained vs. 25±6 years untrained, P=0.683) and weight (78±15vs. 71±15kg, P=0.683) were not different. During exercise average MAP was greater for the RE-trained group in sets 2, 3 and 4 (e.g., set 4: 101±11vs. 92±7mmHg for RE trained and untrained, respectively, post hoc tests all P=<0.012). Zenith MAP and zenith-to-nadir MAP difference demonstrated a training effect (P<0.039). Average MCAvmean and MCAvmean zenith-to-nadir difference was not different between groups (interaction effect P=0.166 and P=0.459, respectively). Despite RE-trained individuals demonstrating greater fluctuations in MAP during RE compared to untrained, there were no differences in MCAvmean. Regular RE may lead to vascular adaptations that stabilise MCAv during RE.

Hypertrophic effects of low-load blood flow restriction training with different repetition schemes: a systematic review and meta-analysis

Objective This systematic review and meta-analysis analyzed the effect of low-load resistance training (LL-RT) with blood flow restriction (BFR) versus high-load resistance training (HL-RT) on muscle hypertrophy focusing on the repetition scheme adopted. Methods Four databases were searched to identify randomized controlled trials that compared the effect of LL-RT with BFR versus HL-RT on muscle hypertrophy. Standardized mean differences (SMD) were pooled in a random effects meta-analysis. Results The overall analysis did not demonstrate significant differences between conditions (SMD = 0.046; p = 0.14). A similar result was observed when we separately analyzed studies that used sets to momentary muscle failure (SMD = 0.033; p = 0.520), sets of 15 repetitions (SMD = 0.005; p = 0.937) and a fixed repetition scheme composed of 75 repetitions (SMD = 0.088; p = 0.177). The analysis considering body region indicates no difference in lower limb exercise between HL-RT and LL-RT with BFR (SMD = 0.00066; p = 0.795) while upper limb exercise favors HL-RT (SMD = 0.231; p = 0.005). Conclusion LL-RT with BFR elicits muscle hypertrophy similar to HL-RT regardless of the employed repetition scheme, although there appears to be a small beneficial effect in favor of HL-RT in upper limb exercise.

Prevalence of text neck syndrome, its impact on neck dysfunction, and its associated factors among medical students: A cross-sectional study.

Students increasingly rely on digital devices, leading to text neck syndrome, a common overuse syndrome caused by repetitive forward neck flexion. This study aimed to determine the prevalence of text neck syndrome among medical students and the resulting neck dysfunction and to investigate the possible associated factors. This cross-sectional study used an online self-developed questionnaire among medical students. Students' characteristics and data about smartphone usage were evaluated for diagnosis. Individuals with at least 3 of the 6 text neck syndrome symptoms and a history of more than four hours a day spent on a smartphone were diagnosed with text neck syndrome. Neck dysfunction was measured using the neck disability index. Descriptive statistics and the chi-square test were used. P values < 0.05 were considered statistically significant. The study found that 31.7% of students with text neck syndrome have mild neck disabilities, with a higher proportion of females (40%). The characteristics that have a significant relation to text neck syndrome include being female (p < 0.0001), overweight (p = 0.025), being right-handed (p = 0.001), using four digital devices or more (p = 0.002), having low levels of physical activity (P = 0.018), and spending more than three hours a day sitting down (P = 0.027). More than a quarter of medical students had text neck syndrome, and most of them had a mild neck disability. Text Neck Syndrome was linked to an increased number of gadgets used, low exercise, and more time spent in a sitting position.

Severely reduced physical performance is already present at the time of admission for stem cell transplantation

ObjectivesPaediatric patients with cancer undergoing allogeneic haematopoietic stem cell transplantation (allo-HSCT) face a high risk for life-threatening infections and transplant-related complications. Therefore, these children should be in the best possible...

Physical Fitness Is Directly Related to Exercise Capacity and Ventilatory Response to Exercise in Men with HFrEF

Background: Heart failure (HF) patients experience reduced functional fitness level (determining the performance of routine, daily activities) and diminished exercise capacity (linked to more effortful activities). Aim: The aim of the study is to assess this relationship using functional fitness tests compared to peak VO2 and VE/VCO2 slope in the context of exercise capacity and ventilatory response to exercise. Methods: A total of 382 men with stable HFrEF (age: 61 ± 10, NYHA class I/II/III/IV: 16/50/32/2%, LVEF: 30.5 ± 8.3%) underwent cardiopulmonary exercise testing (CPX) and a Senior Fitness Test (SFT). Afterwards, the patients were divided according to the 2capacity with peak VO2 ≥ 18 mL/kg/min, those with higher or lower ventilatory responses (VE/VCO2 slope ≥ 35 vs. &lt;35) to the exercise were compared. Results: Patients who covered shorter distances in the 6 min walking test showed worse results in the functional tests (‘stand up and go’, ‘chair stand’ and ‘arm curl’) and CPX (lower peak VO2, shorter exercise time and higher VE/VCO2 slope). Subjects classified into Class D demonstrated the worst results in all elements of SFT; those in Class A demonstrated the best results. Significant differences that were analogous occurred also between classes B and C. Among the participants who reached peak VO2 ≥ 18 mL/kg/min (n = 170), those with VE/VCO2 slope ≥ 35 were characterized by worse physical fitness as compared to those with VE/VCO2 &lt; 35. Conclusion: Reduced exercise tolerance led to worsening physical function in patients with HFrEF. Moreover, limitations in physical fitness seem to be distinctive for those patients showing excessive ventilatory response to exercise slope VE/VCO2 (≥35). The Senior Fitness Test may be considered as a useful tool for assessing comprehensive functional and clinical status and risk stratification in patients with HFrEF, especially those with extremely low exercise capacity.

An examination of the effect of exercise and creatine monohydrate on oral tissues.

Although physical exercise is extremely important for health and a good lifestyle, it can trigger oxidative stress, inflammation, and muscle fatigue. The aim of this study was to determine changes in dental tissues and the mandible created by creatines monohydrate (CrM) supplementation together with low and high-intensity exercise (HIE). The study material comprised Balb/c male mices, which were separated into two groups for the application of low and HIE on a running band. CrM supplement was administered together with the exercise. At the end of the experiment period, dental tissue samples were surgically removed and examined histopathologically and immunohistochemically (TNF-α and lL-1β).As a result of the histopathological examinations, in the pulp, oedema, vascular congestion, and capillary dilatation were seen to be statistically significantly increased in the Group 3 mices that performed HIE compared to the control group (p = 0.001, p = 0.003, p = 0.001, respectively). A statistically significant increase was observed in periodontal ligament (PDL) degeneration, and disruption of the continuity and separation of collagen fibers in Group 3 compared to the control group (p = 0.001). In the immunohistochemical examination, TNF-α and IL-1β positivity was observed in Group 3, and this was significantly increased compared to the control group (p = 0.001, p = 0.000).Exposure of the mices to low and HIE caused histological and immunohistochemical changes in dental pulp and PDL, and it was determined that the use of CrM could have a protective effect against these changes. RESEARCH HIGHLIGHTS: The results of this study showed negative effects of HIE in the dental pulp and PDL, which play an important role in dental health. CrM was seen to be effective in preventing these negative effects.

Exercise capacity in COVID-19 surviving patients: impact of physical rehabilitation

Background: At least 65 million individuals worldwide have Long COVID and despite efforts to explain the effects of exercise prescription on the recovery of these individuals, there is a need to explore its effects on exercise tolerance and cardiorespiratory fitness. Therefore, our main objective was to evaluate the effect of the Physical Rehabilitation Program (PRP) on muscle strength and physical exercise capacity of COVID-19 survivors. Methods: The cohort included 28 patients post COVID-19, each participant performed a comprehensive and multisystem evaluation in two visits, in the pre- and post-PRP: 1st visit = clinical evaluation periods (maximal inspiratory pressure (MIP); maximal expiratory pressure (MEP) and Duke Activity Status Index (VO2peak). 2nd visit= physical evaluation [6-minute Step Test (6MST) and Handgrip Strength (HGS)]. The PRP consisted of breathing exercises, muscle strength exercises for upper and lower limbs and aerobic exercise, 2 or 3 times/week for 03 months. Results: The post-PRP we found: improvement in peripheral [95%CI 2.7 (2.0-3.4), p=0.001, Huge] and respiratory [MIP 95%CI 1.6 (0.9-2.3), p&lt;0.001, Very large) and MEP 95%CI 2.7 (2.0-3.4), p=0.001, Huge)] muscle strength; increase in cardiorespiratory fitness according to estimated-VO2peak [95%CI 2.3 (1.5-3.1), p&lt;0.001, Huge] and the number of steps climbed in the 6MST [95%CI 1.6 (0.9-2.3), p&lt;0.001, Very large]; adaptations resulting lower resting heart rate (HR), higher peak HR, good modulation of HR resulting from stress caused by 6MST; linear and positive association between peripheral and respiratory muscle strength and the number of steps climbed 6MST and greater HR recovery especially post-PRP; recovery-first minute HR remained unchanged post-PRP. Conclusion: In patients post COVID19, we emphasize the great effect of individualized and supervised PRP on the increase in peripheral and respiratory muscle strength/ quality and cardiorespiratory fitness. Despite the gains obtained in PRP, the risk of death based on HR recovery did not change.

Poor cardiac output reserve in pulmonary arterial hypertension is associated with right ventricular stiffness and impaired interventricular dependence.

Pulmonary arterial hypertension (PAH) is characterised by poor exercise tolerance. The contribution of right ventricular (RV) diastolic function to the augmentation of cardiac output during exercise is not known. This study leverages pressure-volume (P-V) loop analysis to characterise the impact of RV diastology on poor flow augmentation during exercise in PAH. RV P-V loops were measured in 41 PAH patients at rest and during supine bike exercise. Patients were stratified by median change in cardiac index (CI) during exercise into two groups: high and low CI reserve. Indices of diastolic function (end-diastolic elastance (E ed)) and ventricular interdependence (left ventricular transmural pressure (LVTMP)) were compared at matched exercise stages. Compared to patients with high CI reserve, those with low reserve exhibited lower exercise stroke volume (36 versus 49 mL·m-2; p=0.0001), with higher associated exercise afterload (effective arterial elastance (E a) 1.76 versus 0.90 mmHg·mL-1; p<0.0001), RV stiffness (E ed 0.68 versus 0.26 mmHg·mL-1; p=0.003) and right-sided pressures (right atrial pressure 14 versus 8 mmHg; p=0.002). Higher right-sided pressures led to significantly lower LV filling among the low CI reserve subjects (LVTMP -4.6 versus 3.2 mmHg; p=0.0001). Interestingly, low exercise flow reserve correlated significantly with high afterload and RV stiffness, but not with RV contractility nor RV-PA coupling. Patients with poor exercise CI reserve exhibit poor exercise RV afterload, stiffness and right-sided filling pressures that depress LV filling and stroke work. High afterload and RV stiffness were the best correlates to low flow reserve in PAH. Exercise unmasked significant pathophysiological PAH differences unapparent at rest.

Pendampingan Aktifitas Senam Kaki bagi Peserta Prolanis Diabetes Melitus di Wilayah Kerja Puskesmas Kujangsari Kota Bandung

Prediabetic individuals participating in the Prediabetes Lifestyle Program (prolanis DM) have exhibited irregular adherence to lower limb exercises, resulting in persistent fluctuations in blood glucose levels. Engaging in lower limb exercises holds substantial benefits for stabilizing blood glucose levels in individuals with diabetes mellitus (DM). This community nursing intervention aims to enhance the ability of prediabetic prolanis participants to perform lower limb exercises. The intervention involves direct assistance and guidance to prediabetic prolanis participants during their lower limb exercise routines. A total of 31 participants were provided with instructional videos on DM-specific lower limb exercises and were evaluated twice over two months during their visits to the Kujangsari Primary Health Center. After the sessions, the lower limb exercises were assessed using a scoring format ranging from 1 to 3, with final results categorized accordingly. Results indicated that 54.8% of participants achieved a 'Good' rating for their lower limb exercise performance. This personalized support and guidance are anticipated to augment the participants' lower limb exercise proficiency and motivation to exercise regularly. The DM-specific lower limb exercise videos are envisioned to serve as a reference for participants, enabling them to pursue self-care by performing these exercises at home and maintaining stable blood glucose levels.

Effect of Digital Therapeutics on Range of Motion, Flexibility, Dynamic Balance, Satisfaction, and Adherence: A Randomized Controlled Trial

This study investigated the effect of digital therapeutics on ROM, flexibility, dynamic balance, satisfaction, and adherence. A sample of 34 volunteers was randomly assigned into a Digital Therapeutic Group (DTG) (n = 17) and a Non-Digital Therapeutic Group (NDG) (n = 17). The groups performed four calf muscle stretches and two hamstring stretches for 4 weeks. Flexibility and balance were evaluated to assess the effectiveness of the exercise program. A survey was conducted to assess subjects’ satisfaction, and exercise performance record papers and video records were assessed for exercise adherence. The paired t-test was used to compare the two populations before and after the program. The independent t-test was used to compare the change scores between groups. In the pre- and post-comparison within each group, the DTG group showed significant differences in all items except the dorsiflexion range of motion (ROM) (p &lt; 0.05). The left straight leg raise (SLR) was significantly different (p &lt; 0.05), and there was a significant difference in exercise satisfaction and participation between the two groups (p &lt; 0.05). DTG showed improved flexibility, dynamic balance, and higher exercise satisfaction and adherence than NDG. The application, providing lower extremity stretching, can improve dorsiflexion ROM, flexibility of the lower extremity, dynamic balance, exercise satisfaction, and exercise adherence.

Indices of exercise induced muscle damage following low load resistance exercise with blood flow restriction in untrained males.

There is conflicting evidence regarding the presence and magnitude of exercise-induced muscle damage (EIMD) following low-load resistance training with blood flow restriction (LL+BFR), which may be related to the protocol implemented or exercise volume. Therefore, the purpose of this investigation was to examine the effects of a 75 repetition (BFR-75) (1×30, 3×15) and four sets to volitional failure (BFR-4x) protocols on indices of EIMD among untrained men. Twelve males with no history of lower-body resistance training during the previous six months volunteered for this investigation. One leg was randomly assigned to BFR-75, and the other to BFR-4x. Participants performed isokinetic, unilateral, concentric-eccentric, leg extension muscle actions at 30% of maximal strength with BFR. Indices of EIMD (limb circumference, perceived muscle soreness, pain pressure threshold [PPT], passive range of motion, and maximal strength [MVIC]) were recorded before exercise and 0, 24, 48, 72, and 96-hours post-exercise for each protocol. There were no significant changes (P>0.05) in limb circumference, PPT, passive range of motion, or MVIC. For both BFR-75 and BFR-4x, perceived muscle soreness increased (P<0.001) similarly 24- (2.5±1.7 AU) and 48-hours (1.9±1.7 AU) post-exercise. There was an increase in muscle soreness 24-48 hours post-exercise for both conditions, which may be due to metabolic stress, but this did not affect the force-generating capacity of the muscle (MVIC), suggesting minimal EIMD. The conflicting evidence of EIMD following LL+BFR may be related to differences in restriction time or overall exercise time.

Exercise Capacity Following Pulmonary Embolism in Children and Adolescents

BackgroundSelf-reported physical activity following pediatric pulmonary embolism(PE) is reduced after diagnosis. However, objectively measured exercise capacity and mechanisms of exercise pathophysiology following PE are unknown. Research QuestionDoes exercise capacity one year after acute PE in children differ from controls? Study Design and MethodsOur case-control study compared exercise capacity and responses to maximal exercise in PE survivors with controls. We also investigated the association of low exercise capacity following PE with prespecified clinical/radiological features at PE diagnosis and elucidated the cause of functional limitations. The primary study outcome was exercise capacity defined by peak oxygen uptake (peak VO2) as a percent of predicted on cardiopulmonary exercise testing (CPET), with <80% predicted peak VO2 considered abnormal/low. Ventilatory inefficiency was defined as VE/VCO2 slope >30 and abnormal stroke volume augmentation as oxygen pulse <10 mL O2.min -1 at peak exercise. Logistic regression was performed to assess the association of prespecified variables with low peak VO2. ResultsWe compared 25 consecutive pediatric PE survivors who completed CPET one-year post-diagnosis with 25 controls who underwent CPET within the same period and were otherwise healthy. Exercise capacity was reduced in 8 of the 25 PE survivors (32%) at one-year post-diagnosis vs. 2 of the 25 control participants (8%) (p:0.034). PE survivors with low exercise capacity demonstrated elevated VE/VCO2 slope (p: 0.01) and a decreased oxygen pulse at peak exercise (p:0.001) consistent with cardiovascular limitation. In univariable analysis, PE category, pulmonary vascular obstruction by Qanadli index, or RV dysfunction at diagnosis was not associated with low exercise capacity. InterpretationAbnormal exercise capacity of cardiopulmonary origin occurred in 1 of 3 pediatric PE survivors despite anticoagulation and irrespective of PE severity, degree of pulmonary vascular obstruction, or RV dysfunction at diagnosis. Cardiorespiratory fitness should be formally considered to develop rehabilitation interventions following pediatric PE.

시합 시즌 중 단주기 저강도 회복 운동 프로그램이 운동 유발성 근육 손상이 있는 엘리트 축구 선수들의 근육 조직 손상 생체지표에 미치는 영향

시합 시즌 중 단주기 저강도 회복 운동 프로그램이 운동 유발성 근육 손상이 있는 엘리트 축구 선수들의 근육 조직 손상 생체지표에 미치는 영향