Contemporary Kidney Transplantation is a component of a series of publications examining solid organ transplant practice. According to the authors, the volume was constructed to address all aspects of transplant care, including history, clinical science, regulation, and transplant practice. Consequently, contributions address diverse topics, including the role of the transplant coordinator, financial coordinator, center and team structure, and quality assessment, in additional to traditional topics, such as immunosuppression and surgical technique. The volume was prepared by the team from the Thomas Jefferson Transplant Program in Philadelphia. Overall, Contemporary Kidney Transplantation is written clearly and concisely. For the reader looking for an overview of transplantation, the volume addresses the important topics at a general level. For example, immunosuppression is covered with 2-3 paragraphs per agent, outlining basic mechanisms and key data. The immunology and pathology sections are particularly well done, with excellent illustrations and concise presentation of complex topics. These chapters will be useful for practicing clinicians, transplant coordinators, fellows, and others. The regulatory and policy chapters are also comprehensive and outline important issues in building a robust quality program. Unfortunately, for the experienced clinician or transplant professional, the scope of the material that the editors sought to cover precludes in-depth discussion of the nuances of transplant practice. In addition, the clinical chapters are written at a level to be useful for medical students or others with limited knowledge of transplant practice. The chapters on kidney transplant contain few figures or tables, and many of the illustrations are of low fidelity. Thus, complex issues (eg, reconstruction of multiple arteries, managing kidneys injured during recovery, addressing the artery with severe atherosclerosis) are not adequately described. There is also inadequate reference to the existing controversies in the field. For instance, there is significant controversy about the role of induction, appropriate maintenance medications, expanded recipient and donor acceptance criteria, and other aspects of clinical care, yet these topics are largely overlooked. For instance, in the chapter on posttransplant management, the authors state, “Beside the limited efficacy, mTOR inhibitors are associated with significant toxicity, which limits further its widespread use.” This is not supported by data, which currently demonstrate the potential value of conversion to mTOR to preserve GFR in appropriately selected patients. The conclusion in the book is the authors’ opinion and should be stated as such, with adequate reference to appropriate clinical trials that support these findings. The authors should present alternative clinical management strategies and note where clinicians and patients can have differences on choices. The clinical chapters did not provide clear, actionable information as is commonly found in true clinical handbooks. For example, a chart with drug dosing and appropriate therapeutic levels, tools to assess kidney donor offers, and comprehensive surgical atlases for key aspects of the procedure are not provided. For the transplant fellow or surgical resident, these would be very useful. Finally, I was concerned about several aspects of the book's content in general. First, all of the contributors were drawn from a single institution, and center practice is presented as fact rather than opinion. For instance, the chapter on graft failure suggests all patients should be tapered off immunosuppression within 6 months, when many centers keep patients on low-dose immunosuppression for life, particularly if there is consideration of retransplantation. As a comprehensive text, a broader distribution of authors and opinions should be included. Second, many of the references are quite dated and do not reflect current approaches to these complex issues. For a review text, the cited sources do not provide an up-to-date reference for the reader to seek additional information. Finally, numerous grammatical errors, missing words, and other production issues distract the reader. In summary, this volume presents a broad overview of transplant practice. It provides an introduction to the field and may be useful for transplant coordinators, pharmacists, and others seeking a broad understanding of transplantation. For the experienced transplant professional, the book does not provide the clear clinical guidance of a true handbook (eg, drug dosing, specific diagnostic approaches) or the comprehensive and evidence-based discussion characteristic of a major text.