Lose Weight Research Articles

The motivation and opportunities for weight loss related to the everyday life of people with obesity: A qualitative analysis within the DO:IT study

Background Unsuccessful weight loss or weight loss maintenance is due to different barriers and physical limitations related to participation in everyday life. It will, therefore, be relevant to investigate the field from an occupational therapy perspective, since occupational therapists are uniquely trained in focussing on people’s resources, meaningfulness and participation in everyday life. Aim The aim was to explore what motivates people to lose weight from an OT perspective and which opportunities people with obesity experience in their everyday lives to achieve and maintain lost weight. Material and Methods A descriptive phenomenological study including 21 semi-structured individual interviews was conducted as part of the DO:IT study. Results The data analysis led to the identification of three main themes: The influence of external circumstances on the desire for weight loss; use of time in everyday life; and changes in habits, routines and structure. Conclusion People who are overweight or obese are motivated to lose weight because of health issues and feeling more comfortable with their body. The opportunities for weight loss lie in creating habits, routines and structuring everyday life activities to facilitate a healthier lifestyle. Significance The findings indicate that an occupational therapist should be part of weight-loss interventions.

Association of trajectory of body mass index with knee pain risk in Japanese middle-aged women in a prospective cohort study: the Japan Nurses’ Health Study

ObjectivesTo investigate whether body mass index (BMI) trajectory, lifestyle and reproductive factors are associated with knee pain risk among middle-aged women.DesignProspective study of the Japan Nurses’ Health Study (JNHS).SettingThe JNHS...

Dry Fasting Physiology: Responses to Hypovolemia and Hypertonicity

Objective: The aim of this study was to provide a deeper insight into dry fasting (DF) physiology. Design: Ten participants performed DF for 5 consecutive days. Methods: The following parameters were monitored daily: cortisol, aldosterone, high-sensitivity C-reactive protein (CRP), erythropoietin, albumin, uric acid, and vitamin C in serum; vasopressin (ADH), adrenocorticotropic hormone (ACTH), renin, angiotensin II, and total antioxidant capacity (TAC) in plasma; hematocrit and erythrocytes in whole blood; osmolality, noradrenaline, dopamine, adrenaline, Na⁺, and K⁺ in 24-h urine; waist circumference and body, urine, and stool weight. Results: The following parameters increased: ADH (60 ± 11%), ACTH (176 ± 34%), cortisol (495 ± 75%), urine osmolality (20 ± 4%), CRP (167 ± 77%), renin (315 ± 63%), angiotensin II (74 ± 21%), aldosterone (61 ± 21%), TAC (80.4 ± 17%), uric acid (103 ± 19%), albumin (18.4 ± 2.4%), erythrocytes (13.4 ± 2.2%), hematocrit (11 ± 1.8%), and the excretion of noradrenaline (40.3 ± 10%) and dopamine (17 ± 5%). The following parameters decreased: waist circumference (8.20 ± 0.61 cm), body weight (7.010 ± 0.3 kg), erythropoietin (65 ± 18%), and the excretion of adrenaline (38 ± 4%) and Na⁺ (60 ± 16%). The excretion of K⁺ remained unchanged. Vitamin C decreased, showing a half-life of 4.8 ± 0.7 days. The percent ratios of lost weight components were: urine (52.2 ± 3.7%), insensible water loss (32.2 ± 1.4%), stool (5 ± 0.3%), and respiratory gases, i.e., expired CO₂ – incorporated O₂ (10.6 ± 5.4%). Conclusion: The mechanisms underlying the hypertonicity and hypovolemia compensation and the ratio analysis of lost weight components were presented. DF demonstrated short-term antioxidant, anti-ischemic, immune-stimulating, anti-edematous, and anti-inflammatory effects. The results may have an impact on developing new concepts for the treatment of edema, obesity, and inflammatory and ischemic diseases.

Novel and emerging devices and operations in the treatment of obesity in children and adolescents

Obesity is among the most common and costly chronic disorders worldwide. Estimates suggest that in the United States obesity affects one-third of adults, accounts for up to one-third of total mortality, is concentrated among lower income groups, and increasingly affects children as well as adults. A lack of effective options for long-term weight reduction magnifies the enormity of this problem; individuals who successfully complete behavioral and dietary weight-loss programs eventually regain most of the lost weight. We included evidence from basic science, clinical, and epidemiological literature to assess current knowledge regarding mechanisms underlying excess body-fat accumulation, the biological defense of excess fat mass, and the tendency for lost weight to be regained. A major area of emphasis is the science of energy homeostasis, the biological process that maintains weight stability by actively matching energy intake to energy expenditure over time. Growing evidence suggests that obesity is a disorder of the energy homeostasis system, rather than simply arising from the passive accumulation of excess weight. We need to elucidate the mechanisms underlying this “upward setting” or “resetting” of the defended level of body-fat mass, whether inherited or acquired. The ongoing study of how genetic, developmental, and environmental forces affect the energy homeostasis system will help us better understand these mechanisms and are therefore a major focus of this statement. The scientific goal is to elucidate obesity pathogenesis so as to better inform treatment, public policy, advocacy, and awareness of obesity in ways that ultimately diminish its public health and economic consequences.

Sleep Duration and Timing in the Medium- to Long-Term Post-Bariatric Surgery.

Sleep duration improves short-term following bariatric surgery; however, little is known about its association with bodyweight medium- to long-term post-surgery. The purpose of this study was to describe sleep duration and its relationship with BMI and body composition. Forty-nine individuals, with a BMI of 36.6 ± 9.8kg/m2, regained 26.4 ± 17.8% of their lost weight 9.5 ± 3.3years post-surgery (range 3-16years). Sleep logs and ActivPAL3 accelerometers were used to assess sleep duration. Participants averaged 7.9 ± 1.6h/day and 8.5 ± 1.7h/day of sleep for weekdays and weekends, respectively (P < 0.01). A positive association between delta weekend-weekday sleep timing midpoint with BMI (β = 0.03, 95% CI = 0.01, 0.06; P = 0.01) was noted in the multivariable-adjusted model. On average, this sample achieved recommended sleep durations medium- to long-term post-surgery. Having an earlier sleep timing midpoint during the weekend may be associated with lower BMI.

Longitudinal Association of Motor Development and Body Weight in Elementary School Children—A 4-Year Observational Study

The inverse association between body weight and physical fitness has been well documented but there remains limited information on the association of weight change with the development of physical fitness, particularly in elementary school children. The present study, therefore, examined the association between change in weight status and the development of physical fitness from the ages 6 to 10 years in 301 Austrian children (55.1% male). Body weight and height were measured according to standard procedures and physical fitness was assessed via the German motor test (DMT 6-18) at baseline and 4-year follow-up. Overweight/obesity was determined using the 90th BMI percentile at each measurement time and children were classified as always normal weight, always overweight/obese, weight gainers (transition from normal weight to overweight/obese) and weight losers (transition from overweight/obese to normal weight). The majority of children (80.1%) maintained normal weight while 7.9% were considered overweight/obese throughout the observation period. A total of 10.3% were classified as weight gainers and only 1.7% were considered weight losers. Weight gainers and those who were overweight/obese throughout the observation period displayed lower improvements in physical fitness, except for flexibility, compared to those who maintained normal weight. Of particular concern is the lack of improvement in cardiorespiratory fitness in weight gainers and overweight/obese children during the elementary school years. Given the detrimental effects of excess body weight on the development of physical fitness, preventive measures that emphasize a healthy body weight and facilitate physical activities that enhance physical fitness should start at young age.

“Christopher Cat”: An Excerpt

“Christopher Cat”An Excerpt Mecca Jamilah Sullivan (bio) Among the teenagers of New York City, Galton Preparatory High School for the Gifted was known for many things. Each spring, it made the New York Times rankings of the best high schools in the city, and the number of graduates it sent to Ivy League universities each fall was a point of great pride for parents and administrators. But for the students themselves, Galton’s reputation was more complicated, and more exciting. Galton students were the rebellious stepchildren of New York’s young intelligentsia—the ones who popped speed and saw therapists and agonized over their grades during the day, then snuck out of their homes and dropped acid and did lines of cocaine with businessmen in fancy clubs downtown while their parents slept at night. This reputation, of course, was earned almost entirely by the white students, and those few black students born wealthy enough to live beyond the burden of racial proof. This was not the case for La Famille. They were a group of hood imports— scholarship students, children of immigrants, and first-generation black middle class. Early in the solidification of their group and regularly thereafter, they bonded over the various sit-down talks they’d each gotten from their parents, lectures so similar they could have been copied from an Official Third World Parenting Handbook and distributed across languages, cultures, and generations until they were imprinted on all the world’s upwardly mobile brown teenage brains. There were classics like “You Will Have to Be Twice as Smart and Work Twice as Hard to Get Half of What You Deserve” and “Not Fair? Life’s Not Fair. Don’t You Know Our History?” The boys often got some version of “All They Expect of You Is to End Up Dead, Gay, or In Jail. It’s Your Job to Prove Them Wrong,” while the girls received the corollary: “They Think You’ll End Up Illiterate, Pregnant and On Welfare at Sixteen. It’s Your Job to Prove [End Page 38] Them Wrong.” Talking with Eric Martinez, Shanté Price, and the Hillings twins, it was clear to Malaya that these dictums ran through the diaspora like blood and bassbeats. They brought La Famille together. Whatever nonsense Galton’s white students got into, the members of La Famille understood that their place was only to listen to the gossip with a delicate mix of disgust and envy, and to go on about their forward-striving lives. Malaya Clondon never mentioned the other sit-downs she got from her parents—If You Don’t Lose Weight, You’re Going to Die—or how much she longed to be the kind of girl who someone would worry might turn up pregnant one day. As La Famille’s charming fat girl—beyond fat, she knew, but still—her role was to be dazzling, the warm and winsome glue that kept the group whole. Compared to the white kids’, La Famille’s infractions were minor, but for them, even small transgressions carried the scent and thrill of danger. Cutting class to give hand jobs in the record store, buying blurry overdubbed VHS pornos from the news stands on 72nd street and watching them in Eric Martinez’s dusty kitchen, sneaking out to meet in Central Park to drink $1.25 bottles of flavored malt liquor and wine coolers from the bodega and smoke Newports late into the night—there were no hard drugs involved in their hijinks, no felonies or glamorous trysts, but it was enough to make them feel alive and almost grown. One morning in December of eleventh grade, a blizzard hit Manhattan unexpectedly, and classes were dismissed after first period. On a nicer day, this would have meant taking it to the park or the two-dollar movie theater in midtown to laugh too loudly and eat popcorn while Shanté and Eric made out in the back row. But the blizzard seemed to be serious, because the train schedules had slowed down, which meant that the kids from Brooklyn, Queens, and the Bronx had to start their treks home now. RayShawn Carter, Shanté, and the...

Glycemic control of newly-diagnosed type 2 diabetes with different baseline body mass index under the standardized metabolic disease management model

Objective To explore the glycemic control of newly-diagnosed type 2 diabetes with different levels of baseline body mass index (BMI) after 6 months treatment under the standardized metabolic disease management model. Methods (1) 163 patients of newly-diagnosed type 2 diabetes were divided into normal weight (BMI 18.5-23.9 kg/m2), overweight (BMI 24.0-27.9 kg/m2), and obese (BMI≥28 kg/m2) groups according to baseline BMI, the blood glucose and lipids levels were compared among 3 groups. (2) The blood glucose levels were compared among 3 groups after 6 months of standardized management. (3) The overweight and obese patients were divided into group weight loss≥5% and group weight loss<5% or weight gain in 6 months. The blood glucose levels were compared. Results (1) At baseline, overweight and obese groups had higher homeostasis model assessment for insulin resistance and lower high density lipoprotein-cholesterol compared with normal weight group. (2) After 6 months of treatment, HbA1C and HbA1C reduction showed no difference among 3 groups (normal, overweight and obese) after adjusted by baseline HbA1C. The rate of HbA1C 0.05). (3) After 6 months of treatment, 32.28% overweight and obese patients lost weight by ≥ 5%, while HbA1Cand HbA1Creduction showed no difference between 2 groups (weight loss≥5% and weight gain or weight loss 0.05). Group weight loss≥5% had better glucose control (92.68% vs 77.91%, P<0.05). Conclusions As BMI increased, insulin resistance and lipid disorders were more serious in newly-diagnosed type 2 diabetes. After 6 months of standardized metabolic management, newly-diagnosed type 2 diabetes with different baseline BMI and weight changes both achieved good glycemic control. In addition, patients losing weight equal to or more than 5% achieved higher attainment of HbA1C targets. Key words: Newly-diagnosed type 2 diabetes; Body mass index; HbA1C; Weight changes

A study of nutritional status, development of malnutrition and food consumption in hospitalized patients

Purpose: To investigate the nutritional status of patients on admission and during hospital stay, the factors leading to weight loss, and to evaluate patient satisfaction of hospital food. Methods: On admission, Nutritional Risk Screening (NRS-2002), weight, height, Body Mass Index (BMI), mid upper arm circumference (MAC) measurements were carried out; serum total protein and albumin levels were recorded. Upon discharge, measurements of weight, MAC were repeated, along with a food satisfaction questionnaire. Results: Patients with NRS-2002&gt;3, BMI&lt;20, were classified as nutrionally at risk which were 43.6% and 9.4% respectively. Of the patients, 77% lost weight (2.6±1.9 kg). Patients who were determined to be malnourished on admission by BMI and NRS-2002 stayed longer in hospital (p&lt;0.0 and p&lt;0.001, respectively). The relationships between weight loss and lenght of stay, use of medications and period of starvation were significant (p&lt;0.0001, for each). Of the patients, 49.9% did not satisfy with the hospital food. Conclusions: Nutritional status of hospitalized patients should be screened with NRS-2002, assessed and monitored.&#x0D; Keywords: NRS-2002, hospital malnutrition, hospital food services

Probiotics May Help You Lose Weight

Probiotics May Help You Lose Weight

A single gestational weight gain recommendation is possible for all classes of pregnant women with obesity

ObjectivesObesity is a known risk factor for adverse pregnancy outcomes; however, appropriate gestational weight gain (GWG) may mitigate these risks. We investigated whether the singular 2009 Institute of Medicine (IOM) GWG guidelines were appropriate for all women with obesity, or whether separate recommendations were needed by class. MethodsThis cross-sectional study of pregnant women with obesity used 2014 U.S. birth certificate data (N=646,642) and included only term pregnancies. Adjusted log-binomial regression models examined the relative risk of adverse maternal, obstetric, and neonatal outcomes for pregnant women with class I–III obesity who: lost weight during pregnancy, gained below IOM guidelines, or gained above IOM guidelines, compared to women who gained within IOM guidelines. ResultsMost women (55.1; 95% CI: 55.0-55.3) gained above IOM guidelines. As BMI severity increased, significantly fewer women had excessive GWG (Class I: 61.6%, 95% CI: 61.4-61.7; II: 50.7%, 95% CI: 50.4-50.9; III: 41.1%, 95% CI: 40.8-41.4). All classes of women with obesity who lost weight during pregnancy or gained below had a significantly decreased risk for caesarean delivery (RR (95% CI) class I: 0.92 (0.90-0.94); II: 0.91 (0.89-0.93); III: 0.92 (0.90-0.93)) and large-for-gestational age (LGA) births (class I: 0.80 (0.77-0.83); II: 0.76 (0.73-0.78); III: 0.73 (0.70-0.75)), but significantly increased risk of small-for-gestational age (SGA) births (class I: 1.34 (1.26-1.43); II: 1.38 (1.28-1.49); III: 1.35 (1.24-1.46)). ConclusionThe observed pattern of association was the same for all obese classes, hence evidence supports a possible singular GWG recommendation for all women with obesity, regardless of class.

Efficacy of chalcone and xanthine derivatives on lipase inhibition: A systematic review.

Losing weight has significant impact on chronic disease management. Orlistat, a lipase inhibitor, has alternative effect for weight controlling. To find more candidates, we conducted a review of chalcone and xanthine derivatives regarding their anti-lipase activity. Eight databases were searched including PubMed, Scopus, Web of Science (ISI), Virtual Health Library (VHL), System for Information on Grey Literature in Europe (SIGLE), Global Health Library (GHL), EMBASE, and Google Scholar in August 2018. We found chalcone scaffold was more effective on lipase inhibition than xanthine scaffold. Among 19 investigated chalcones, only isoliquiritigenin and licuroside demonstrated an effect on preventing weight gain and increase in the total cholesterol and total triglycerides aside apart from their high activity on inhibiting lipase. Effect and type of inhibition of individual chalcones differed depending on their structure. In addition, very few studies investigated xanthine compounds and their activities were inconsistent. We suggest more studies investigate the ability of chalcones and modifying their structure to find out other compounds with higher efficacy.

Occurrence of malnutrition in cancer patients during radiotherapy

Objective To investigate the malnutrition status of cancer patients undergoing radiotherapy, and to provide research basis for later nutrition intervention. Methods Using convenient sampling method, 380 patients with cancer treated by radiotherapy in Shanghai and Zhejiang provincial Class Ⅲ Grade A hospitals from February to November 2018 were selected as the research subjects. The incidence of malnutrition, laboratory indicators on admission and discharge, and the incidence of significant weight loss during hospitalization were investigated. Malnutrition was assessed by Patient-Generated Subjective Global Assessment Scale (PG-SGA) . Results Among 380 cancer patients receiving radiotherapy, 48.9% (186/380) suffered from or suspected malnutrition at admission, of which 7.6% (29/380) suffered from severe malnutrition. At discharge, 64.2% (244/380) of radiotherapy patients developed or suspected malnutrition, of which 18.9% (72/380) suffered from severe malnutrition. In addition, 56.3% (214/380) patients lost weight during radiotherapy, and 12.4% (47/380) patients showed significant weight loss. Compared with that at admission, the levels of serum albumin and hemoglobin decreased significantly (P<0.05) . Conclusions The incidence of malnutrition is high in cancer patients during radiotherapy. Early nutritional assessment should be given at admission and early nutritional intervention should be given to malnutrition patients. Key words: Neoplasms; Radiotherapy; Malnutrition; Weight loss

Symptom Burden in Patients With Home Care Who Are at Risk for Malnutrition: A Cross-Sectional Study.

In Sweden, patients in early palliative stages of illness are cared for in primary care and often offered home care. Many are older and at risk for malnutrition, but little is known about their symptom burden and nutritional problems. This cross-sectional study divided older patients in home care into those with and without risk for malnutrition and compared symptom burden in the 2 groups. Participants were patients in Stockholm County (n = 121) in early palliative stages of disease cared for at home by primary care professionals from 10 health-care centers. The Mini Nutritional Assessment (MNA) was used to identify risk for malnutrition. Symptoms and/or nutritional status in patients with and without risk were assessed with the Functional Assessment of Anorexia/Cachexia Therapy (FAACT), Patient-Generated Subjective Global Assessment Short Form (PG-SGA), and Edmonton Symptom Assessment System (ESAS). Forty-two percent of the patients were at risk for malnutrition (MNA). Appetite (P = .012), tiredness (P = .003), and anxiety (P = .008) were worse in these patients than in those without risk (ESAS; significance level, P ≤ .015). Patients at risk were also more concerned about how thin they looked (P = .006), agreed more strongly that their family or friends were pressuring them to eat (P = .000; FAACT; significance level, P ≤ .029), had a higher symptom burden (P = .005), had lower physical activity (P = .000), and more lost weight over time (P = .032; PG-SGA; significance level, P ≤ .040). This study adds a more detailed picture of the symptom burden in older patients at risk for malnutrition. Such information is needed to identify risk for malnutrition earlier and improve patients' health.

Positive reinforcement by general practitioners is associated with greater physical activity in adults with type 2 diabetes

ObjectiveIn a sample of adults with type 2 diabetes mellitus (T2DM), the aim of this study was to examine whether self-reported physical activity level is associated with recall of specific...

Psychological factors influencing weight regain after bariatric surgery

Background Approximately 15 to 40% of bariatric patients regain a significant percentage of their weight lost after surgery. Among psychological variables, control and self-efficacy loci are associated with behaviors related to weight loss. Also, family support can be a risk or protection factor for the maintenance of weight loss. Aim To evaluate the association between psychological variables with weight maintenance or regain after bariatric surgery. Material and Methods We evaluated 97 patients at 4.1 ± 3.4 years after their bariatric surgery. They answered questionnaires about self-efficacy to lose weight, locus of weight control and family functioning style. Regain after surgery was also calculated, through self-report. Results Seventeen percent of patients gained weight. Locus of control (Z = -3.09, p < 0.01), family identity (Z = -3.71, p < 0.01) and self-efficacy (Z = -2.44, p = 0.01), differentiated patients who maintained weight loss from those who re-gained at least 15% of their lost weight. An inverse and significant relationship was observed between the percentage of weight regain and locus of control (r = -0.42, p < 0.01), family identity (r = -0.36, p < 0.01) and self-efficacy (r = -0.34, p <0.01). Conclusions The psychological variables "locus of weight control" and "family identity" are inversely and moderately associated with weight regain in patients subjected to bariatric surgery.

Changes in Microbiota and Bacterial Protein Caseinolytic Peptidase B During Food Restriction in Mice: Relevance for the Onset and Perpetuation of Anorexia Nervosa.

Microbiota contributes to the regulation of eating behavior and might be implicated in the pathophysiology of anorexia nervosa. ClpB (Caseinolytic peptidase B) protein produced mainly by the Enterobacteriaceae family has been identified as a conformational mimetic of α-MSH, which could result in similar anorexigenic effects. The aim of this study was to highlight the role of the microbiome and the ClpB protein in deregulation and self-maintenance of anorexia pathology. Male C57Bl/6 mice were undergone to the ABA (Activity-Based Anorexia) protocol: after 5 days of acclimatization, both ABA and LFA (Limited Food Access) mice had progressively limited access to food until D17. At the end of protocol, the plasma ClpB concentration and Enterobacteriaceae DNA in colonic content were measured. As expected, dietary restriction induced lost weight in LFA and ABA mice. At D10, colonic permeability and plasma concentration of the ClpB protein were significantly increased in LFA and ABA mice vs. controls. At D17, plasma concentration of ClpB was increased in LFA and ABA mice and, it was correlated with proportion of Enterobacteriaceae in the faeces. These abnormally high ClpB concentrations and all associated factors, and therefore might contribute to the initiation and/or perpetuation of anorexia nervosa by interfering with satiety signaling.

Analysis of Compression Strength on Plastic Brick Material

Plastic waste has a negative impact on the environment, handling plastic waste by utilizing plastic waste and sand to make plastic bricks. This study aims to make plastic bricks, test the compressive strength of plastic bricks and determine the density. Making plastic stones using the experimental method, this method of experimenting with experience to prove themselves a statement that is learned. Maximum compressive strength test results in samples 1, 1 kg of plastic: 1 kg of sand = 141.42 kg/cm2. Sample 2, 1.15 kg plastic: 0.85 kg sand = 117.23 kg / cm2 and Sample 3, 0.85 kg plastic: 1.15 kg sand = 112.50 kg / cm2. Average mass weight sample 1 (1.25 kg) and the average lost weight of sample 1 (0.75 kg), average weight mass of sample 2 (1.39 kg) and lost average sample weight 2 (0.61 kg), mass average weight of sample 3 (1.3 kg) and loss of average sample weight 3 (0.7 kg) with total material used 2 kg. Based on the results of compressive strength tests, plastic bricks meet quality standards (SNI 15-2-94-1991). Thus this research can replace industrial products and maintain a healthy environment.

1785P - The patient voice: An Irish survey of nutrition attitudes & access to dietetic care throughout the cancer journey

BackgroundThe attitudes of cancer patients towards nutrition and nutrition care has never been captured in Ireland. An awareness of the nutritional needs and attitudes of cancer patients along with a review of their experiences would help inform service planning. MethodsIn September 2018, a national survey was conducted to examine patient attitudes towards nutrition and access to dietetic services during their cancer journey. Patients diagnosed or treated in Ireland since 2015 were asked to complete a 25-item survey (available online and at 20 hospitals across Ireland). ResultsIn total, 1085 valid responses were received (63% female, mean age 58 years). All major cancer groups were represented & 33% had metastatic disease. Overall, 45% reported suffering from a diet-related problem and 44% reported weight loss since diagnosis. Muscle loss was noted by 52%. Amongst weight losers, 42% were ‘unhappy/worried’ while 27% reported being ‘delighted/happy’. Although 80% are ‘always/usually’ weighed in clinic, just 43% reported that they are ‘always/usually’ asked about diet. Nutrition was rated ‘very/extremely’ important by 89% of respondents. Only 39% had received dietary advice from a dietitian and 74% rated this advice as ‘very/extremely’ helpful. Overall, 57% of those who did not see an RD said they would have liked more support with diet. While 58% reported trying general healthy eating as a result of their diagnosis, 38% and 32% admitted trying at least one alternative dietary strategy or avoiding a specific food due to their diagnosis, respectively. ConclusionsWhile nutrition is highly important to Irish cancer patients, fewer than half surveyed had accessed a dietitian. Weight and muscle loss are common, but their significance is not always understood by patients. Almost half used alternative dietary strategies, highlighting the need to screen oncology patients for potentially restrictive diet or supplement use to guide appropriate referrals and education. Legal entity responsible for the studyThe authors. FundingIrSPEN. DisclosureAll authors have declared no conflicts of interest.

A453 Personalized, Multi-Component Interventions for Behavioral Weight Management: Yes, but How? A Hybrid Intervention of Compulsory and Personalized Elements Based in Self-Determination Theory

Bariatric surgery is the most effective treatment for severe obesity. However, with more than 40% of postoperative bariatric patients experiencing excessive weight regain (i.e., 25%+ of total lost weight) and the majority of patients regaining some weight, there is a need for individualized behavioral interventions to promote sustained, lifelong maintenance of surgical weight loss. Given the multifactorial nature of weight regain, interventions must be multicomponent and personalized. This recommendation represents best practice; however, clinicians may lack knowledge or experience for pragmatic implementation. This session will address these issues, highlighting self-determination theory (SDT) as optimal for conceptualizing personalized treatments. Emphasis will be placed on the utility of the three components of SDT – autonomy, competence, and relatedness – to inform personalized, holistic interventions for patients who have lost or are trying to lose weight. SDT-based, personalized behavioral interventions can be tailored for both surgical and non-surgical populations with obesity, and they are ideal for preventing recidivism following weight loss. A brief overview of the BOSS intervention (Bariatric Outcomes: Sustaining Success) will be provided: this is an SDT-based, multicomponent intervention for promoting sustained weight loss and preventing recidivism. Five adult case examples will highlight how the intervention is tailored across SDT domains of autonomy, competence, and relatedness. Preliminary outcome data will also be provided: all patients are actively losing weight or maintaining weight loss. The session will demonstrate the implementation and personalization of evidence-based interventions, emphasizing the need for both compulsory and individualized elements within a multi-component program for lifelong behavioral weight management.