SUMMARY Ultimately, treatment results must be evaluated by how well the individual patient is served on a lifetime basis. This is particularly difficult to assess in a highly mobile society, as it takes years to learn what the long-term consequences of early treatment decisions will be. The outcome of decisions relating to repair of lip, nasal, and palatal tissues can be evaluated by 21 years of age. For the patient appearing before cleft lip-palate review boards, it is possible to evaluate the results of soft-tissue repair techniques. The lip and nose will not change significantly except for those changes associated with the aging process. Skeletal and dental relations will likewise remain stable as long as the natural dentition is preserved. Premature loss of teeth, however, introduces a variable that many times is not widely appreciated. Treatment outcomes relating to early treatment decisions pertaining to the dentition are most difficult to evaluate on a long-term basis. The cleft patient is at greater risk for premature loss of teeth because of compromised periodontal support in the cleft areas and congenitally missing teeth that will require replacement. Traditionally, prosthetic treatment has been viewed as being more conservative than surgery. A fixed prosthesis, however, will have to be replaced several times during a lifetime and will require additional home care efforts. When this is not done, teeth are lost, complicating prosthetic treatment. Removable prosthetic devices clearly create an unfavorable environment periodontally. When they are used to compensate for underlying skeletal dysplasia and obturate fistulae, anchoring teeth may become compromised, leading to their premature loss. Thus, early treatment decisions can be viewed as being conservative only when based on the long-term consequences. “Conservative” treatment involving a removable prosthesis to compensate for underlying skeletal deformity and to obturate fistulae, rather than utilizing orthognathic surgery with simultaneous alveolar bone grafting and closure of fistulae, will have long-term ramifications. Premature loss of abutment teeth secondary to periodontal disease and fabrication of a prosthesis that may become more complicated and ultimately fail for the same reason may leave the adult in the third, fourth, or fifth decade of life edentulous with moderately advanced loss of alveolar bone, patent oral fistulae, and a shallow maxillary vestibule. Because of the loss of vertical dimension, a class III relation will become more accentuated secondary to vertical overclosure. Ultimately, an osteotomy may be necessary to enable the patient to wear a prosthesis. In retrospect, while surgery may have appeared to be the more radical form of treatment for the adolescent, when viewed in the context of long-term consequences, it may have proved to be the most conservative. One cannot therefore necessarily view nonsurgical treatment as being conservative and any treatment that involves orthognathic surgery as being radical. Surgical procedures that preserve natural structures on a lifetime basis may ultimately prove to be the most conservative treatment alternatives available.