Experimental studies of bearing capacity and settlement of foundation on clay soils under regime cyclic loading are conducted in this paper. Tests were conducted in trays using a hydraulic system (ASIS); it allowed determining the base settlement, stress and deformation in the soil. The results of experimental studies are presented in graphs of the dependence of settlement and deformation on the loading mode. New data on the regularities of the stress-strain condition of clays under cyclic loading were obtained. The significance of the results obtained for construction is that under regime cyclic loads, soil deformation increases within the compressible thickness, as well as the base settlement with different intensity in all loading blocks. The most intensive development of soil deformations and base settlement occurred at the initial stage of loading up to 300 cycles, during the transition to the second stage, stabilization occurred up to 2700 cycles. Loss of bearing capacity occurred at the third stage of loading after reaching the limit state of the soil mass in the compressible thickness of the slab foundation.