The selection of drugs plays an important role in treatment. Good quality drugs administered appropriately after analyzing the condition of both disease and patient will act as nectar. The concept regarding standardization and quality control of Ayurvedic drugs can be traced back to ancient times. Kashaya Kalpana is a pharmaceutically viable and therapeutically effective formulation but has a shorter shelf life. Kashaya Kalpana can be easily modified into syrup form which is widely acceptable due to palatability, longer shelf life, and easy administration. Mustadi Yoga, a Kashaya preparation from Yogaratnakara mentioned in Krimi Roga Chikitsa is made into syrup form. The present work aims at reporting the physicochemical evaluation of Mustadi syrup and is standardized as per the physicochemical parameters of API, which will help for further research.