This article is aimed at studying methods for optimizing the pile field in order to ensure the greatest use of the bearing capacity of piles, adopted in the project, considering the most unfavorable design combinations of forces. The object of the study is a multi-storey apartment building on a slab-pile foundation with a regular grid of piles, which clearly shows the imperfection of the calculation methods, due to the incomplete use of the bearing capacity of a significant number of piles, but the methods described in the article are also applicable to other buildings on slab-pile foundations, especially the difference between the original scheme and the optimized scheme will be clearly visible on the example with longer piles in less bearing soils, spread over the entire depth of the foundation. The purpose of this study is to study methods for optimizing a pile field, to study the methodology for using these methods on a specific example and compare them in terms of the parameters of using the bearing capacity of piles: the absolute and relative value of the minimum load on the pile, the absolute and relative value of the maximum load on the pile, the absolute and relative value average load per pile, as well as their comparison of economic efficiency. In the course of the article, numerical modeling was used, using the finite element method and analysis of the results of multivariate calculation. The result of this article is the application of pile field optimization methods to the multi-storey building on a slab-pile foundation, the evaluation of each of the methods and their comparison according to these indicators, as well as an understanding of the further development of this topic.