The article considers the current situation of the structural and technological imbalance in the Russian economy, as well as the nonproportional distribution of the factors of production and financial resources. The need for structural reforms in industrial production and income generation has been shown. The author discusses priorities of structural and investment policy, direction of new technological breakthrough in the long-term national strategy of entering international technological space. Special features of development of key economic sectors have been analyzed. In conclusion, quantitative estimates of economic dynamics in the long term up to 2035 have been given, which are predetermined by implementation of planned measures of structural and investment policy that provides potential for GDP growth until 2035 at a rate of no less than 3.5% on average per year.