Long-term Effects Of Physical Activity Research Articles

FEASIBILITY OF A PHYSICAL ACTIVITY PROGRAM AT A SHELTERED WORKSHOP FOR ADULTS WITH MULTIPLE DISABILITIES

Providing physical activity programs for people with multiple disabilities may be a means to increase their physical function and independence; thus, reducing their risk for becoming institutionalized and/or developing additional disabilities. However, little has been done to develop such programs for this population. The purpose of this study was to assess the feasibility of a physical activity program at a sheltered workshop for adults with multiple disabilities including mental retardation, Down syndrome, autism, speech/language impairments, behavior disorders, hyperactivity, and developmental delays. Sixteen clients were asked and 11 volunteered to participate in the program. Six of the 11 volunteers completed assessments before and after the program to determine strength, flexibility, and motor skills. Three of these 6 did not participate in the activity program and served as a control group. The remaining three volunteers who completed all assessments, participated in the physical activity program (45 min, 2d/wk, 8 wk) which consisted of a warm-up, exercises utilizing Thera-bandTM elastic bands, and a cool-down. Adherence was 100% for these participants. Slight improvements were observed for the majority of tests in 2 of the participants. In the other participant, no improvements were observed. For controls, no changes or slightly lower test scores were observed. The results of this study are encouraging and indicate that this limited activity program (45 min, 2d/wk, 8 wk) was beneficial to those who participated. Additional studies are needed to assess the long-term effects of physical activity on populations with multiple disabilities.

No effect of long-term physical activity on the glycemic control in type 1 diabetes patients: a cross-sectional study

Background: The main purpose of the present study was to assess the relation between long-term physical activity and glycemic control in patients with type 1 diabetes mellitus.Methods: Medical data and blood samples for the determination of glycosylated hemoglobin (glyHb) were collected in 221 consecutive type 1 diabetes patients between 18 and 45 years of age without late complications. A self-report questionnaire was used to determine the degree of physical activity. Correlation coefficients and analysis of variance were used for statistical analyses.Results: No correlation was observed between the different levels of physical activity and glycemic control. Females showed a significantly higher total physical activity index than males (p=0.004), mostly due to the leisure time activity index. More active patients used a lower amount of insulin (r=−0.20, p=0.002) than less active patients.Conclusions: Glycemic control was not found to be associated with long-term physical activity in type 1 diabetes patients. Physical activity did not negatively affect long-term glycemic control.

Physical activity and risk of colon cancer: the Physicians' Health Study (United States).

Previous studies indicate that physical activity is related inversely to colon cancer risk. However, details regarding that association--whether a dose-response relation exists, whether the relation differs between non-obese and obese persons, the effect of long-term physical activity--are unclear. We examined these issues in the Physicians' Health Study (United States). Physical activity was assessed at baseline among 21,807 men, aged 40 to 84 years, and again 36 months later. Men were followed for an average of 10.9 years (from baseline) during which 217 developed colon cancer. After adjusting for potential confounders (including age, obesity, and alcohol intake), the relative risks for colon cancer associated with vigorous exercise in times per week (< 1, 1, 2-4, 5+, at baseline) were 1.0 (referent); 1.1 (95% confidence interval [CI] = 0.7-1.7); 1.2 (CI = 0.8-1.6); and 1.1 (CI = 0.7-1.6), respectively; P trend = 0.6. Physical activity was not associated significantly with colon cancer risk either among non-obese or obese men. When we used physical activity assessments at baseline as well as at 36 months, physical activity again was unrelated to colon cancer risk. These data do not support the hypothesis that physical activity reduces the risk of colon cancer. Plausible alternate explanations for the null finding include misclassification of physical activity and the potential for increased surveillance for colon cancer ('screening effect') among those physically active.

Physical Activity and Skeletal Health in Adolescents

A considerable amount of research into osteoporosis has focused on the management and treatment of bone loss in later life. More recently, a limited amount of research has been directed toward the development of an optimal level of peak bone mass during the adolescent and early adult years. While genetics is a major determinant of bone status, there is considerable evidence that physical activity is an important nonhereditary factor. Studies on adults suggest that the positive effect of physical activity on bone is modest in the short term but may be quite powerful with more intense activity that overloads the muscular system for a longer time period. In children, however, our knowledge about the long-term effects of physical activity on bone accretion is incomplete. This paper presents a review of the pediatric literature dealing with the relationship of physical activity to bone mineral density status in the adolescent population.

Effects of exercise training on the chemical composition of plasma LDL.

The purpose of the present study was to determine the effects of exercise training on the chemical composition of plasma low-density lipoprotein (LDL). Thirteen men (mean age +/- SE, 47.2 +/- 1.5 years) were examined before and after 14 weeks of endurance-oriented exercise training (3 to 4 d/wk, 30 to 45 min/d). Although calculated plasma LDL concentrations remained unaltered (3.49 +/- 0.24 versus 3.65 +/- 0.23 mmol/L), changes in the chemical composition of LDL (increased LDL free cholesterol, cholesterol ester, and phospholipid content) were associated with a reduction in adiposity, umbilical girth, and basal plasma insulin and glucose concentration with training intervention. Increases in LDL molecular weight and particle diameter were associated with a reduction in fat mass, plasma triglyceride concentration, and basal plasma glucose concentration with physical activity. The LDL lipid-to-protein ratio also increased (P < .01) with training by 7%, primarily due to an increase in LDL free cholesterol content (P < .01). These findings indicate the formation of LDL particles that are more cholesterol enriched and protein poor with exercise training, which provides additional evidence for the cardioprotective effect of long-term physical activity.

Long-term effect of physical activity on energy balance and body composition.

We studied the effect of an increase in physical activity on energy balance and body composition without interfering with energy intake (EI). Sixteen women and sixteen men, aged 28-41 years, body mass index 19.4-26.4 kg/m2, not participating in any sport before the start of the experiment, prepared to run a half-marathon competition after 44 weeks. Measurements of body composition, EI and energy expenditure (EE) were performed before (0 weeks), and 8, 20, and 40 weeks after the start of training. Body composition was measured with hydrodensitometry and isotope dilution, and EI with a 7 d dietary record. EE was measured overnight in a respiration chamber (sleeping metabolic rate (SMR)) and in a number of subjects over 2-week intervals with doubly-labelled water (average daily metabolic rate (ADMR)). ADMR showed an average increase of 30% in both sexes from the start of training onwards while SMR tended to decrease. EI showed a tendency to drop from week 20 to week 40 in the men and a tendency to increase from week 20 to week 40 in the women. Body mass (BM) did not change in both sexes until the observation at 40 weeks when the median value of the change in men was -1.0 kg (P < 0.01; Wilcoxon signed-rank) while the corresponding change of -0.9 kg in the women was not statistically significant. Body composition changes were most pronounced in men as well. Based on changes in BM, body volume and total body water, men lost 3.8 kg fat mass (FM) (P < 0.001; Wilcoxon signed-rank) and gained 1.6 kg protein mass (P < 0.01; Wilcoxon signed-rank) while the corresponding changes in women were 2.0 kg (P < 0.05; Wilcoxon signed-rank) and 1.2 kg (P < 0.05; Wilcoxon signed-rank). In men the loss of FM was positively correlated with the initial percentage body fat (Pearson r 0.92, P < 0.001). In conclusion, body fat can be reduced by physical activity although women tend to compensate for the increased EE with an increased EI, resulting in a smaller effect on BM and FM compared with men.

DIETARY MEASURES OF PHYSICAL ACTIVITY

The relationships between cardiovascular fitness, body fatness, and the number of calories required to maintain stable body weight over a baseline period of three weeks were studied in 21 healthy obese males aged 20-44 years who participated in a controlled feeding experiment at the Division of Epidemiology (formerly the Laboratory of Physiological Hygiene) of the School of Public Health, University of Minnesota, in August 1980-June 1981. statistically significant relationships were found between the number of calories actually consumed per kg of body weight (kcal/kg) and body fatness (r = -0.79, p = 0.001), and number of calories consumer per kg of body weight and physical work capacity (VO2 max) (r = 0.76, p = 0.001). Using body fatness quartiles, the caloric intake per kg of body weight and VO2 max decreased progressively as body fatness increased through its four quartiles. These relationships were also seen when reported caloric intake from a three-day food record was used; however, the magnitude was attenuated. On the other hand, caloric intake unadjusted for body weight, whether actual or reported, was unrelated to both body fatness and VO2 max. To determine whether these relationships hold true for less obese subjects, the authors have also analyzed and compared their results with the data from previously reported feeding experiments done at the University of Minnesota. Correlations between body fat indices and actual caloric intake were similar for both studies. Therefore, the authors conclude that in these relatively young, healthy, and sedentary males with a wide range of body fatness and body weight, the observed relationships between caloric intake adjusted for body weight, body fatness and VO2 max reflect habitual physical activity. These data confirm epidemiologic observations of an inverse relationship between caloric intake per kg of body weight and body fatness, and provide a rationale for using caloric intake adjusted for body weight as a measure of long-term habitual physical activity. Thus, these data bolster the interpretation that an inverse relationship between caloric intake per kg of body weight and mortality reflects a positive health effect of long-term physical activity. This index may be particularly useful in large population studies.