In recent times, drilling groundwater wells for irrigation, domestic, and industrial uses is increasing at a high rate in Saudi Arabia, meaning that groundwater is becoming a primary water resource. In the study region, over-exploitation and unsustainable performance severely deteriorate groundwater. Therefore, it is important to monitor the groundwater levels and quality as well as to detect the hydraulic parameters in order to plan and maintain groundwater sustainability. Knowledge of aquifer hydraulic parameters and groundwater quality is essential for the productivity planning of an aquifer. Therefore, this study carried out a thorough analysis on measured depth to groundwater data (2017 and 2022), borehole pumping test records, and chemical analysis of the collected water samples, especially in the presence of overexploitation and scarcity of recharge scale. To accomplish this aim, measurements of 113 groundwater wells (including 103 water samples) and analysis of 29 pumping tests between step and long-duration tests were made of all aquifer characteristics. These parameters consist of well loss, formation loss, well efficiency, specific capacity, transmissivity, hydraulic conductivity, resulted drawdown, and physiochemical parameters. Thematic maps were generated for all parameters using the geographic information system (GIS) and diagrams to strategize the groundwater productivity in Al-Madinah Al-Munawarah Province. The estimated hydraulic parameters are highly variable. Four distinct portions were identified for aquifer potentiality based on these varying ranges. Both the north and east of the region are good for groundwater productivity due to good aquifer materials, whereas the southwestern and western portions have relatively poor values. The analyzed groundwater was categorized as fresh to slightly salty water, with two primary chemical types identified showing a prevalence of mixed NaCl and Ca-Mg-SO4/Cl water. Finally, groundwater productivity assessment predicts that the aquifers can support the Al-Madinah Al-Munawarah Province demand for several years if certain well distributions are adopted and for a few hours/day of pumping rate. The maps that have been created can be examined to aid in making decisions related to hydrology.