Ab initio configuration interaction calculations are performed to study the chemisorption of atomic H on a Fe(110) surface. The lattice is modeled as an embedded three-layer, 40-atom cluster with the Fe atoms fixed at the bulk position. Fe 3d orbitals are explicitly included on five Fe atoms on the surface. Hydrogen strongly binds to the Fe(110) surface at the long-bridge, short-bridge, and quasi three-fold sites. The calculated adsorption energies are 2.76, 2.73, and 2.71 eV, respectively. H-surface bonding at the on-top Fe site is more than 0.4 eV weaker. The calculated H-surface distances are 0.89, 1.03, and 0.87Åfor H at the long-bridge, short-bridge, and quasi three-fold sites, respectively, which agrees well with the LEED value of 0.9 ± 0.1Å. The H-surface stretching vibrational frequencies are calculated to be 1070, 1066, and 1073 cm −1, at the long-bridge, short-bridge, and quasi three-fold sites, respectively. The work function of Fe(110) decreases on H adsorption. The present calculations indicate that H diffusion into the bulk through the short-bridge site will have a much higher activation barrier than via the long-bridge and quasi three-fold sites.