Lone Survivor Research Articles

Carcinoma of the urinary bladder in patients receiving cyclophosphamide.

Hemorrhagic cystitis is a common side effect of cyclophosphamide therapy not observed with other alkylating agents. In five patients receiving cyclophosphamide by mouth for prolonged periods with large cumulative dosage urinary-bladder tumors fatal to four and requiring cystectomy in the lone survivor developed. These observations strongly suggest chemical carcinogenicity of this drug in the production of these tumors. Increasingly, cyclophosphamide is being used for non-neoplastic disease. These circumstances suggest careful follow-up observation of patients in whom hemorrhagic cystitis from this drug develops for evidence of bladder cancer, as well as restraint in use of cyclophosphamide for non-neoplastic diseases if alternative therapy is available.

Random utility models with equality: An apparent, but not actual, generalization of random utility models

A probabilistic model for choice, and preference, is introduced that includes (Tversky's) elimination by aspects model, and the random utility model, as special cases. The model is based on a covert sequential elimination process, the element that is finally chosen in a simple choice experiment being the eventual lone survivor of the elimination process. The model leads us to question the usual form of simple choice experiments, in which a subject must (eventually) choose one of the currently available alternatives, and to suggest that a much more realistic experimental design would allow the subject the no-choice option, i.e., he may refuse to accept any of the currently available alternatives.

Herpesvirus hominis Encephalitis

Recent experience suggests that Herpesvirus hominis is the commonest cause of sporadic necrotizing encephalitis in man. We documentedH hominisencephalitis in seven patients aged 8 months to 70 years. Five of these seven patients were admitted to our hospital in a 13-month period of time. Four patients were treated with idoxuridine, and three of these died. One patient who received a full course of idoxuridine yieldedH hominisfrom postmortem brain samples in titers approximately equal to those found in the pretreatment brain biopsy specimen. The lone survivor was left with significant neurological deficits. Two patients were treated with cytarabine and, although they remain alive, both are hospitalized in chronic care institutions. The duration and severity of illness manifest by these patients may have adversely affected the outcome of therapy.

Iowa Is Home of Lone Survivor of "The Gallant Six Hundred. "

Iowa Is Home of Lone Survivor of "The Gallant Six Hundred. "

Herbert John Fleure, 1877-1969

Herbert John Fleure died at his home in Cheam, Surrey, on 1 July 1969, at the advanced age of 92 years. His great eminence in not one, but a range of disciplines that in the course of his career he professed as head of university departments of zoology, geology, anthropology (physical and social) and geography (particularly human geography) must be unique. Even to his last days he was engaged in research in fields of physical anthropology and human history to which subjects he was closely drawn throughout his life. To him, Man was a part of Nature; living organisms and their environment were inseparable, and must be studied together, hence his desire that geography and anthropology should form a combined study. For more than half a century he was revered as a father of British geography, first as one of a small group of pioneers in the subject’s early formative years, and later as a lone survivor and leader known personally to, and regarded with warm affection by thousands of teachers of geography the world over. For their interests he strove relentlessly, seeing in the teaching of that subject a keystone in the promotion of international understanding and peace—a theme for which he was pleading to the end of his career, and which coloured his whole philosophy. Family history He was born on 6 June 1877 in Guernsey and by his ancestry was very much a ‘Channel Islander’. His father, John Fleure, accountant to the States, Guernsey, lived from 1803 until 1890, and was a member of an old family of both Guernsey, Alderney and Sark ancestry. He married Marie Le Rouge tel of Jersey, who lived from 1841 until 1914. There were two children of this marriage; Herbert John was the younger (his elder sister died unmarried in 1913) and he was in fact only thirteen years of age when his father died at the age of eighty-seven. This remarkably long combined lifespan of father and son—from 1803 until 1969—must surely be rare, covering, as it did, a momentous period of world history and social and technological changes.

Magnetization of the Perry Formation of New Brunswick, and the rotation of Newfoundland: Reply to G. W. Pearce and G. N. Freda

Except for one point we do not wish to argue the details of our paper. The data are on record and the curious reader is in a position to decide for himself. However, we feel we must point out that the magnetization of site BH2 cannot be envisaged as made up of one main component which is the lone survivor after cleaning at 600 C, and of several other components oriented at random, as Pearce and Freda suggest, since the removal of random components could not cause the observed mean direction change of more than 30 (see our Table 11, (Robertson et al. 1968, p. 1179)). Oddly enough Pearce and Freda do agree with the main point of our paper when they state Robertson et al. have indeed clearlv demonstrated that Black's data cannot be conkdered as conclusive ... The magnetism of the Perry Formation is so complex that the results are inconclusive and cannot be used as a basis for arguing that Newfoundland has rotated.

The surgical management of pulmonary valve atresia

Isolated atresia of the pulmonary valve is a rare congenital malformation. Two types are recognized; one in which the right ventricle is small and its cavity slit-like in character, and another in which this ventricle is large. Pulmonary blood flow is dependent upon a patent ductus. If the lives of the infants are to be salvaged, the lesion must be diagnosed, and operation performed before the ductus closes. Pulmonary valvotomy is recommended when a large right ventricle is present. When this ventricle is small, a palliative superior vena cava to pulmonary artery anastomosis is advocated. Seven infants with pulmonary atresia are reported. Three died before operation could be undertaken and four had pulmonary valvotomy performed. Of these four, one died postoperatively and three survived to be discharged from hospital. One of these died at six months with reclosure of the pulmonary valve orifice; one died following a repeat operation; and the lone survivor at eighteen months continues to do well, but has some residual pulmonary stenosis.

"The Eternal Against the Expedient": Structure and Theme in Shaw's The Apple Cart

·"THE ETERNAL AGAINST THE EXPEDIENT": STRUCTURE AND THEME IN SHAW'S THE APPLE CART IN The Apple Cart (1929) Shaw was principally concerned with an analysis of ideal personal distinction, and he attempted to show how his protagonist, King Magnus, is as truly great as his Latinate name would imply. In the Shavian view, the individual's preeminence results from the wealth and variety of his resources and from his independent moral strength which he can evince both in crisis and in the conditions of ordinary life. These are the chief facets, too, of Caesar's greatness in Caesar and Cleopatra; Magnus is, in reality, a subdued and crafty Caesar. Like Caesar, he is a modified man of action, great by what he is as much as by what he does. He also possesses originality of the sort which Shaw ascribed to Caesar: "Originality gives a man an . air of frankness, generosity, and magnanimity by enabling him to estimate the value of truth, money, or success in any particular instance quite independently of convention and moral generalization."! Shaw's searching inquiry into his theme provides not only the philosophic context of the play but its structural unity as well. At all costs, Shaw was determined to present Magnus's genius, not summarily in the abstract, but suggestively in the specific situations which it confronts in its effort to prevail or to survive. The structural germ of the play is contained in the preliminary conversation between the two private secretaries of the king, Sempronius and Pamphilius. This scene, in its precision of phrasing and in its neatly interlocking conceptual patterns, furnishes, as Edmund Wilson has observed, the opening strands of an elaborate "music" of ideas characterizing the play itself.2 In the secretaries' discourse, an airy lightness of tone, a deftness of thought, and a graceful formality of utterance establish a somewhat Mozartian atmosphere for the play; and there is also something of the canny wisdom of the Mozartian Figaro in these two competent underlings. In this scene Shaw not only arouses curiosity about his protagonist through a calculated use of the delayed entrance, but also in part establishes the king's superiority through the subject of the secretaries' discourse, the personality 1. "Notes to Caesar and Cleopatra," Caesar and Cleopatra (New York, Brentano's, 1906), p. 122. First published, 1901. 2. "Bemard Shaw at Eighty:' The Triple Thinkers (New York. 1948). pp. 182-184. 99 100 MODERN DRAMA September of Sempronius' now deceased father.s He was, according to his son, a special kind of artist who believed too simply in his own creationspageants and other large scale celebrations-which were always the result of artifice imposed upon nature. In ethics and philosophy, as well as in art, he was "a Ritualist," since he used his mind only within areas defined by custom and distrusted the insights which might have been provided by unfettered natural powers. If, in his worship of ritual, he denied the importance of the discriminating reason, he was also deficient in the converse faculty, imagination. Though his imagination had within limits a certain fertility, it lacked scope, flexibility, and vigor. He possessed in abundance , however, that pernicious form of the imagination often characterizing the romantic temperament, the tendency to embroider the objects of actual perception with the most fantastic attributes. Apt to be deluded by meretricious appearances, he was unable, then, to see things as they really existed. If he was reprehensibly active in distorting his perceptions, he was also reprehensibly literal in denying the reality of what he could not see. In rejecting all but the physically observed, he revealed that he was insensitive to spiritual influences 'and, in general, to the more elusive facets of experience. He presented, then, the paradox of the professed antiromantic who is all too blindly romantic-or uncritically subjective-in dealing with fact. His culture , furthermore, failed to engage him fundamentally and became a self-indulgent, passive amusement provided for him by others. When he was a ship-wrecked lone survivor on an island off the Scottish coast and had neither companion card players nor a church to order his life, he found himself without the resources necessary to...

The Lone Survivor of the Navaho Trading Expedition to Utah Territory

The Lone Survivor of the Navaho Trading Expedition to Utah Territory