Abstract. The aim of the work is to improve the theoretical and methodological foundations for the development of Industry 4.0, the use of technologies of which opens up new opportunities for domestic enterprises operating in a changing business environment and economic and political instability. To achieve the set goal and fulfill the tasks, general and specific methods were used in the work, namely; abstract-logical - to determine the features of Industry 4.0; methods of analysis and synthesis - to highlight the characteristic features of business entities using Industry 4.0 technologies; generalization – to form an arsenal of Industry 4.0 technologies. SWOT analysis method - to identify strengths and weaknesses from the implementation of Industry 4.0 technologies by domestic enterprises and new opportunities and threats that await them. Results. The article considers the main approaches to the interpretation of the economic category «Industry 4.0». The list of technologies included in the arsenal of Industry 4.0, which open up opportunities for digital development of modern domestic enterprises, is summarized and formed. The article highlights the opportunities and main characteristics inherent in business entities that have implemented digitalization of their business models. A SWOT analysis of Industry Development 4.0 was carried out. in Ukraine, which made it possible to identify the main problems and opportunities characteristic of Ukrainian enterprises. Barriers to the implementation of Industry 4.0. technologies at domestic enterprises are highlighted. The conclusion is formulated that the introduction of Industry 4.0 technologies in the practical activities of domestic enterprises opens up new opportunities for them, because its main indicators are: process automation, logistics rationalization and production effi ciency improvement. However, domestic enterprises face a number of obstacles on the way to digitizing their business, because so far the country has not formed favorable conditions for this. Ukraine is slowly moving towards the transition to Industry 4.0. For rapid industry development 4.0. Ukraine needs synergy of three factors: the state apparatus, business and the educational system. Keywords: Industry 4.0, Fourth Industrial Revolution, digitalization of enterprises, SWOT analysis, digital development.