The paper is devoted to the study of methods and mechanisms for the formation and development of innovative logistics infrastructures in the Republic of Armenia, the factors that determine the effective application of these methods and mechanisms, as well as the state policy of stimulating innovation and investment. Under current economic conditions, it is especially important for the Republic of Armenia to stimulate innovation and investment activities. The latter requires the formation of the institutional foundations of innovation activity, as well as the intensification of interaction between science, business and the state. The issue of stimulating the activities of companies in the IT sector deserves special attention. In this context, it is especially important to study the possibilities and international experience in creating effective innovative logistics infrastructures in the Republic of Armenia. The paper also presents the mechanisms for the development of an innovative economy. Based on them the concept of creating effective innovative logistics infrastructures is proposed. To apply the concept, a set of appropriate actions has been developed and justified, which will significantly stimulate the creation of an effective innovation system.