Logistics center is a mordern logistic facility. The distribution center location determines the operational efficiency of logistics system. The optimum location of distribution center is important to transportation. In order to improved the algorithm's efficiency, elite strategy was introduced based on the standard immune algorithm. The improved algorithm avoid trapping into local optimal solution and solving the problem more slowly. The role of the elite strategy is to make the optimal solution attractively in the next cycle. This method sovles problem both quantitatively and qualitatively, which makes final solution better in accordance with practical demands.