Localized Hypertrichosis Research Articles

Localized Hypertrichosis after Sclerotherapy

Localized Hypertrichosis after Sclerotherapy

Case of pigmented neurofibroma with hypertrichosis with no association to neurofibromatosis

Pigmented neurofibroma (PNF) is a rare cutaneous tumor that has been observed in patients with or without neurofibromatosis (NF). This tumor is histologically characterized by the coexistence of scattered melanin-laden cells and benign spindle cells with neural differentiations. Hypertrichosis is the excessive growth of hair on non-androgen-dependent areas of the body. It has been reported that hypertrichosis may sometimes overlie a neurofibroma. We highlight a case of PNF with hypertrichosis on a 17-year-old woman with no associated NF. We also discuss the possible underlying pathogenic mechanism of a localized hypertrichosis in PNF patients.

Anomalies cutanées des sinus dermiques communicants : à propos de 2 cas

Skin abnormalities in the spinal lumbosacral region of infants are not infrequent. Physicians should look for underlying spinal malformations. We report 2 cases of dermal sinus in infants revealed by severe, acute meningitis. The dermal sinus is an abnormal tract between the skin and underlying neural structures, most often located in the lumbosacral region. It may end blindly in the subcutaneous tissues, or it may extend into the medullary space. The diagnosis should be suspected in patients with other skin findings: localized hypertrichosis, subcutaneous lipomas, hyperpigmented lesions, etc. It must be distinguished from the very frequent coccygeal pits (4% of newborns), which require no treatment. Magnetic resonance imaging should be done every time the diagnosis is suspected. Recurrent bacterial meningitis or meningitis caused by unusual bacteria is frequently associated with dermal sinus. A variety of neurologic abnormalities have been described: sensory changes, motor weakness, reflex changes, abnormal bowel and bladder function, etc. Infants generally have few neurologic symptoms, such as delayed walking or sphincter control. Orthopaedic abnormalities are rare. The dermal sinus tract needs to be detected at an early stage in order to avoid these complications, which can be prevented by early surgery.

A Case of Faun Tail Naevus Treated by Intense Pulsed Light

A faun tail is abnormal lumbar hypertrichosis that is characterized by a wide, often triangular or lozenge-shaped patch of coarse hair, and this hair is usually several inches long. Faun tail is a rare entity. A 36-year-old male presented with a triangular shaped hair tuft with terminal hair on the lumbosacral area, and he'd had this unusual hair since birth. There were no neurologic signs or abnormality on his spine X-ray. The MRI scan showed disc degeneration and loss of lodordosis. We report here on a rare case of faun tail, which was a form of localized hypertrichosis on the lumbosacral area, and this was successfully treated with intense pulsed (IPL) light.

Localized Hypertrichosis in a Pediatric Patient—What Is the Mechanism for Excess Hair Growth?

Localized hypertrichosis is an uncommon complaint among pediatric dermatology patients. We highlight an instance of localized hypertrichosis due to an underlying diffuse neurofibroma in a patient with known neurofibromatosis 1. The classification and possible underlying pathogenic mechanisms of localized hypertrichosis in pediatric patients is discussed.

Local hypertrichosis associated with a human papillomavirus type 1-induced wart

Conflict of interest: None declared. Sir, Various causes for acquired localized hypertrichosis have been described, including application of topical steroids, infections, local trauma, long‐standing inflammatory dermatoses, venous incompetence, and the application of splints and casts.1–3 A 7‐year‐old Japanese girl noted a verrucous papule on her right knee 7 months before the first examination. It was a firm, dark red, circumscribed and elevated papule 8 mm in diameter with a hyperkeratotic surface. The most interesting finding in the case was the hypertrichosis seen alongside of the wart lesion (Fig. 1A). She had noticed the increased hair 3 months before the first examination. She did not complain of any symptoms. She was healthy and physical examination revealed no particular finding other than the skin lesion. The suspected diagnosis of a viral wart with an acquired, local hypertrichosis was made, and after informed consent was obtained, the verrucous papule was removed by scalpel. During the follow‐up period of about 9 months, the hypertrichosis gradually reduced (Fig. 1B) and finally disappeared (Fig. 1C).

Familial anterior cervical hypertrichosis

To the Editor: Anterior cervical hypertrichosis is a very rare form of primary localized hypertrichosis.1 To our knowledge, only 2 cases of familial anterior cervical hypertrichosis have been reported.2-3 Here we describe a patient with anterior cervical hypertrichosis whose family history shows that 2 other individuals in 2 generations of her family had the same hypertrichosis localized to the anterior cervical region.

Mental retardation in a boy with anterior cervical hypertrichosis

Anterior cervical hypertrichosis (ACH) is a rare form of localized hypertrichosis with 15 previously reported cases. ACH has been considered to be a dominant phenotype, either X-linked or autosomal [OMIM 600457]. ACH was associated with hereditary motor and sensory neuropathy (HMSN) in one family, in which the proband also exhibited severe chorioretinal degeneration and optic atrophy, probably as a different entity [OMIM 239840]. A Mexican boy with congenital ACH associated with moderate mental retardation, abnormal EEG, mild microcephaly, hypertrichosis on the back, and hallux valgus is presented here. An equal sex ratio found in 16 reported cases as well as the suggestion of a paternal age effect in one report appear most consistent with an autosomal dominant mode of inheritance for this trait. It remains unclear if isolated ACH, ACH-HMSN, or other associated findings reported in patients with ACH, including unusual features found in our case, are part of ACH or fortuitous associations, due to the small number of affected patients and different ascertainment biases present in previous reports.

Asymptomatic skin coloured plaques over the lower limbs

Received: Septeber, 2004. Accepted: March, 2005. Source of Support: Nil. A 40-year-old female presented with two asymptomatic plaques over her left shin of one year’s duration. Clinical examination revealed two, skin coloured, almost annular, well defined plaques, located over the anterolateral aspect of the left shin, measuring about 2 cm in diameter. Surrounding the lesions were a few areas of localized hypertrichosis [Figure 1]. Examination of other body parts, including the mucosae, hair, and nails, did not reveal any abnormality.

Localized Hypertrichosis following BCG Vaccination: Case Report

An eight-month-old Turkish boy presented at the Fatih University Pursaklar outpatient clinic with excessive hair on his left shoulder. The history was that 15 days after receiving BCG vaccination at the age of two months, new hairs were noticed at the site. Examination revealed an aggregation of dark hairs on an area measuring 4x3cm at the site of the vaccination with the scar of BCG vaccine at the base. We would like to draw attention to this hitherto unreported localized hypertrichosis complicating BCG vaccination. Key Words: BCG vaccine, hypertrichosis, side effect Nigerian Journal of Paediatrics 30(3) 2003: 93-95

Coexistence of acquired localized hypertrichosis and lipoatrophy after lupus panniculitis

As described by Wendelin et al1 in their excellent review, acquired localized hypertrichosis can appear after several forms of local inflammation, such as areas subject to friction, osteomyelitis, vaccination sites, or linear scleroderma. We would like to add lupus panniculitis to the list of causes, as a new one with special pathogenetic implications.

Long-Lasting Hypopigmentation Induced by Long-Pulsed Alexandrite Laser Photo-Epilation

BACKGROUND Long-lasting hypopigmentation induced by laser hair removal systems has been reported. OBJECTIVE To evaluate clinical aspects of a female Caucasian that developed long-lasting hypopigmentation in the arms and forearms after photodepilation with a long-pulsed alexandrite laser. METHOD A 29-year-old Caucasian female (phototype III) with localized hypertrichosis in the upper limbs was submitted to long-pulsed alexandrite laser-assisted hair removal. One treatment session was done with these laser parameters: a pulse width of 2 ms, a spot of 7 mm, and fluence energy of 18 J/cm2. RESULTS The patient developed long-lasting hypopigmentation (more than 6 months) in the arms and forearms after a single treatment session of photodepilation. CONCLUSION Long-pulsed alexandrite laser may induce reversible melanocyte suppression and long-lasting hypopigmentation.

Localized Hypettrichosis Associated with Penorbital Neurofibroma: Clinical Findings and Differential Diagnosis

Background: Congenital localized hypertrichosis in the periorbital region is an uncommon finding. The authors report two patients with hypertrichosis and cutaneous hyperpigmentation overlying a periorbital neurofibroma.Methods: In addition to a complete ophthalmic and systemic examination, the patients underwent computed tomography of the head and biopsy of the tumor.Results: Case 1 previously had received a diagnosis of neurofibromatosis type I. On examination, hyperpigmentation, hypertrichosis, and swelling in the right supraorbital region were noted. A computed tomographic scan showed a tumor in the same region. The tumor was removed, and a plexiform neurofibroma was diagnosed. Case 2 was admitted with hyperpigmentation, hypertrichosis, and swelling of the left half of her face. Other signs of neurofibromatosis were absent. A computed tomographic scan showed a tumor, which was underlying the skin changes. Results of histologic examination of the biopsy specimen showed a plexiform neurofibroma.Conclusion: Neurofibroma-associated hypertrichosis should be considered in the differential diagnosis of congenital localized hypertrichosis.

Acquired Circumscribed Hypertrichosis in the 'Costaleros' Who Bear the 'Pasos' During Holy Week in Seville, Spain

Repeated irritation, friction, or inflammatory changes continuing over the long term may produce the growth of coarse and long hair in some cutaneous areas. Csillag's 1 classic description in 1921 describes a localized hypertrichosis on the left shoulder in men who bore heavy sacks in the ports. There are later publications describing localized hypertrichosis in areas inflamed by erysipelas, 2 repeated pinching in the mentally weak, 3 following excoriated insect bites 4 or appearing near inflamed joints, 5 after a prolonged period of occlusion by plaster of paris, 6 and others. The acquired circumscribed hypertrichosis on the costal area of the lower aspect of the neck with which the costaleros bear the pasos during Holy Week in Seville, Spain, is described. Report of Cases. In July 1992, a 27-year-old man with a well-developed athletic constitution presented with moderate acne on his body; a high sebum excretion rate; and an

Ipsilateral post-cast hypertrichosis and dyshidrotic dermatitis

Post-cast hypertrichosis and dyshidrotic dermatitis are not uncommon separately. Yet, the simultaneous occurrence of both conditions in an individual is rare. A patient with both localized hypertrichosis and ipsilateral dyshidrotic dermatitis following multiple fractures and cast application is reported. The clinical presentation, management, spontaneous resolution, and/or response to therapy of post-cast hypertrichosis and dyshidrotic dermatitis that occurred concurrently in an individual were similar to that described when these conditions occur independently. The acquired conditions that may be associated with localized hypertrichosis are summarized and the postulated mechanisms of pathogenesis for dyshidrotic dermatitis are reviewed. The diagnosis of post-cast hypertrichosis in this patient was suspected based upon the distribution and temporal association of the hypertrichosis to the location and placement of his cast, and confirmed by excluding other causes of acquired localized hypertrichosis. Also, the possibility that in this individual either the trauma to his bones, the cast on his arm, or both had an etiologic role in promoting the development of dyshidrotic dermatitis is suggested.

Cutaneous meningioma underlying congenital localized hypertrichosis

A 28-year-old man had a circumscribed hypertrichotic area on the left lumbar region since birth. A biopsy specimen showed numerous normal-appearing hair follicles and arrector pili muscles. In the subcutaneous layer a mass of dense collagenous connective tissue formed the background in which ill-defined foci of meningothelial cells in nests and pseudovascular spaces were seen. Collagenous structures (pseudopsammoma bodies), some of which showed calcification (psammoma bodies), were also seen. A diagnosis of cutaneous meningioma was made.

Familial cervical hypertrichosis with underlying kyphoscoliosis

A family with congenital localized hypertrichosis transmitted in an autosomal dominant pattern is presented. The excessive hair growth was localized to the cervical region and was associated with underlying kyphoscoliosis. No additional cutaneous or skeletal abnormalities were identified. To our knowledge these are the first cases of familial congenital cervical hypertrichosis associated with underlying kyphoscoliosis reported in the literature.

Postphlebitic Localized Hypertrichosis

To the Editor.— The clinical manifestations of postphlebitic syndrome are edema, increased pigmentation, dermatitis, and indurated cellulitis; however, hair growth over varicose veins is very rare in this condition.1 Report of a Case.— We recently examined a 42-year-old woman with a three-year history of congestive heart failure and tricuspid valve insufficiency secondary to chronic obstructive pulmonary disease. One year previously she had recurrent thrombophlebitis of the limbs. We noticed hyperpigmentation and hair growth over thrombotic veins in the patient (Figure). Comment.— Thrombophlebitis of a superficial varicose vein, as in this or any other case, is made evident by painful induration with inflammation of the overlying skin. Localized sweating is sometimes seen, but localized hypertrichosis over thrombotic veins is extremely rare.1We could not find any elucidating explanation about the mechanism of this type of hypertrichosis. Hyperpigmentation and hair growth over thrombotic veins in patient.

Acquired localized hypertrichosis

Acquired localized hypertrichosis

Transient Circumscribed Hypertrichosis Following Chickenpox

A 6-month-old infant with chickenpox developed localized hypertrichosis surrounding chickenpox scars. This manifestation followed a mild and uncomplicated course of the disease. Transient localized hypertrichosis is not men tioned in the literature as a complication of chickenpox.