Local Temperature Research Articles

Ultrasound -Induced Thermal Effect Enhances the Efficacy of Chemotherapy and Immunotherapy in Tumor Treatment.

The inadequate perfusion, frequently resulting from abnormal vascular configuration, gives rise to tumor hypoxia. The presence of this condition hinders the effective delivery of therapeutic drugs and the infiltration of immune cells into the tumor, thereby compromising the efficacy of treatments against tumors. The objective of this study is to exploit the thermal effect of ultrasound (US) in order to induce localized temperature elevation within the tumor, thereby facilitating vasodilation, augmenting drug delivery, and enhancing immune cell infiltration. The selection of US parameters was based on intratumor temperature elevation and their impact on cell viability. Vasodilation and hypoxia improvement were investigated using enzyme-linked immunosorbent assay (ELISA) and immunofluorescence examination. The distribution and accumulation of commercial pegylated liposomal doxorubicin (PLD) and PD-L1 antibody (anti-PD-L1) in the tumor were analyzed through frozen section analysis, ELISA, and in vivo fluorescence imaging. The evaluation of tumor immune microenvironment was conducted using flow cytometry (FCM). The efficacy of US-enhanced chemotherapy in combination with immunotherapy was investigated by monitoring tumor growth and survival rate after various treatments. The US irradiation condition of 0.8 W/cm2 for 10 min effectively elevated the tumor temperature to approximately 40 °C without causing any cellular or tissue damage, and sufficiently induced vasodilation, thereby enhancing the distribution and delivery of PLD and anti-PD-L1 in US-treated tumors. Moreover, it effectively mitigated tumor hypoxia while significantly increasing M1-phenotype tumor-associated macrophages (TAMs) and CD8+ T cells, as well as decreasing M2-phenotype TAMs. By incorporating US irradiation, the therapeutic efficacy of PLD and anti-PD-L1 was substantially boosted, leading to effective suppression of tumor growth and prolonged survival in mice. The application of US (0.8 W/cm2 for 10 min) can effectively induce vasodilation and enhance the delivery of PLD and anti-PD-L1 into tumors, thereby reshaping the immunosuppressive tumor microenvironment and optimizing therapeutic outcomes.

NIR activated upconversion based nanocatalysts for CT/PA imaging-guided triple synergistic PTT/PDT/CDT cancer treatment

Photodynamic therapy (PDT), as a non-invasive treatment, is expected to be widely used in clinical cancer treatment. In this paper, a near-infrared (NIR) light responsive Lu2O3:Yb/Er/Li-Ce6@MIL-101/GOx-PDA (LCMGP) nanodiagnostic platform was prepared for CT/PA imaging-guided multimodality synergistic therapy. Under 808 nm laser irradiation, Lu2O3:Yb/Er/Li-Ce6 (LC) NPs in the nano-diagnostic platform are activated and sensitized by NIR light, resulting in the generation of more single-linear oxygen (1O2) for efficient PDT. Glucose oxidase (GOx) and MIL-101 (Fe) nanozymes can utilize their excellent enzyme cascade catalytic properties and peroxidase-like catalytic properties to undergo glycolysis reactions and catalyze the decomposition of endogenous hydrogen peroxide (H2O2), producing a large amount of hydroxyl radicals (•OH), achieving efficient chemodynamic therapy (CDT). The functionalized modification of polydopamine (PDA) endows the LCMGP nanoparticles with higher photothermal conversion efficiency, which can prompt high local temperature at the tumor site under the irradiation of NIR light to achieve efficient photothermal therapy (PTT). In addition, hyperthermia accelerates the catalytic efficiency of the nanozymatic cascade of LCMGP nanoparticles to enhance ROS production while increasing cellular uptake, resulting in PTT-induced PDT/CDT synergistic effect (96%). Based on the excellent photothermal conversion effect of PDA and the high X-ray attenuation effect of Lu/Fe, the LCMGP nanotherapeutic system demonstrates good CT/PA imaging function, providing new insights and ideas for imaging-mediated multimodal synergistic therapy.

Localized thermal levering events drive spontaneous kinetic oscillations during CO oxidation on Rh/Al2O3

Unravelling kinetic oscillations, which arise spontaneously during catalysis, has been a challenge for decades but is important not only to understand these complex phenomena but also to achieve increased activity. Here we show, through temporally and spatially resolved operando analysis, that CO oxidation over Rh/Al2O3 involves a series of thermal levering events—CO oxidation, Boudouard reaction and carbon combustion—that drive oscillatory CO2 formation. This catalytic sequence relies on harnessing localized temperature episodes at the nanoparticle level as an efficient means to drive reactions in situations in which the macroscopic conditions are unfavourable for catalysis. This insight provides a new basis for coupling thermal events at the nanoscale for efficient harvesting of energy and enhanced catalyst technologies.

Polypeptide nanoparticles conjugated with an NIR-II organic dye for TRPV1 channel blockade enhance mild phototheranostics

Photothermal therapy (PTT) has attracted attention as a highly effective non-invasive treatment method. However, the high localized temperatures (>50 °C) required for its treatment will inevitably cause damage to the surrounding normal tissues. Therefore, it is important to develop novel and effective strategies to achieve mild photothermal therapy (mPTT). The overexpression of heat shock proteins (HSPs), a widespread heat stress protein, leads to the generation of heat resistance in cancer cells, which seriously affects the therapeutic effect. Thus, inhibiting the expression of HSPs to reduce the heat resistance of tumor cells is expected to enhance the therapeutic effect of mPTT. Here, we successfully synthesized a fluorescent probe bonded with an amphiphilic polypeptide to a cyanine dye and achieved physical encapsulation of the blocker SB705498 through a self-assembly process. SB705498 promotes transient receptor potential vanilloid member 1 (TRPV1) channel blockade that can inhibit the translocation of the heat shock transcription factor 1 (HSF 1) by blocking the influx of calcium and thus affecting the expression of HSPs, which has the potential to enhance the thermotherapy of cancer under mild conditions. In addition, the nanoparticles enabled NIR-II fluorescence imaging with good stability and high photothermal conversion efficiency (48.10 %). Therefore, this study provides a new strategy for realizing precise mPTT(<45 °C) guided by NIR-II imaging. Statement of significanceInhibition of overexpression of heat shock proteins (HSPs) in cancer photothermal therapy (PTT) is expected to enhance the therapeutic effect of mild photothermal therapy (mPTT). In this study, we synthesized a fluorescent probe bonded to cyanine dyes with amphiphilic polypeptides and physically wrapped the blocker SB705498 through a self-assembly process. As a transient receptor potential vanillin 1 (TRPV1) channel blocker, SB705498 inhibits heat shock transcription factor 1 (HSF1) translocation by blocking calcium ion influx, thereby improving mPTT efficacy by inhibiting the expression of HSPs. The nanoparticles also enable NIR-II fluorescence imaging with good stability and high photothermal conversion efficiency (48.10 %). Thus, this study provides a new strategy for NIR-II mPTT.

Mixed Convection Boundary Layer Flow over a Solid Sphere in AL203-Ag/Water Hybrid Nanofluid with Viscous Dissipation Effects

The current study aims to investigate how heat transfer and skin friction develop by modifications in the fundamental advantages of fluids in the presence of mixed convection boundary layer flow over on a sphere in hybrid nanofluids. The numerical solutions for the reduced Nusselt number, local skin friction coefficient temperature profile, and velocity profiles are discovered and clearly presented. The Eckert number, the mixed convection parameter λ, and the nanoparticle volume fraction are all investigated and described. It is found that increasing the volume percentage of nanomaterial in nanofluid enhanced the value of the skin friction coefficient. The low density of nano oxides in hybrid nanofluids, such as alumina, also contributes to reduced friction between fluid and body surface. The findings of a computational investigation demonstrate that the use of a hybrid nanofluid, composed of nanometal and nano-oxide in the form of , has the potential to decrease skin friction while maintaining heat transfer characteristics comparable to that of Ag/water nanofluid. The findings in this publication are new and will be useful to boundary layer flow researchers. It can also be applied as a guideline for experimental investigations with the goal of reducing the cost of operation

Pulsed laser induced plasma and thermal effects on molybdenum carbide for dry reforming of methane

Dry reforming of methane (DRM) is a highly endothermic process, with its development hindered by the harsh thermocatalytic conditions required. We propose an innovative DRM approach utilizing a 16 W pulsed laser in combination with a cost-effective Mo2C catalyst, enabling DRM under milder conditions. The pulsed laser serves a dual function by inducing localized high temperatures and generating *CH plasma on the Mo2C surface. This activates CH4 and CO2, significantly accelerating the DRM reaction. Notably, the laser directly generates *CH plasma from CH4 through thermionic emission and cascade ionization, bypassing the traditional step-by-step dehydrogenation process and eliminating the rate-limiting step of methane cracking. This method maintains a carbon-oxygen balanced environment, thus preventing the deactivation of the Mo2C catalyst due to CO2 oxidation. The laser-catalytic DRM achieves high yields of H2 (14300.8 mmol h−1 g−1) and CO (14949.9 mmol h−1 g−1) with satisfactory energy efficiency (0.98 mmol kJ−1), providing a promising alternative for high-energy-consuming catalytic systems.

Evolution of Local Temperature after Thermal Disbudding in Calves: A Preliminary Study

Evolution of Local Temperature after Thermal Disbudding in Calves: A Preliminary Study

Numerical simulation of local and upwind temperature stratification on flow and dispersion in a bi-dimensional street canyon.

The thermal effect mainly includes boundary temperature stratification and the local thermal effect. The combined effect of these factors on flow and dispersion in a bi-dimensional canyon was investigated by the RANS and LES methods to evaluate their performance. The results, including the flow field, turbulent kinetic energy, temperature, heat flux, pollutant concentration and fluxes, were compared with the data from wind tunnel experiments. The comparison results showed that the RANS method severely overestimated the impact of windward heating on the flow in the canyon because of the lack of simulated flow separation ability and the limitation of the Boussinesq model, leading to an incorrect flow field and an incorrect temperature and concentration. In contrast, LES performed better mainly because of its ability to simulate flow separation. LES regenerated the right vortexes, flow field and low wind velocity. LES slightly overestimates the overall temperature in the canyon because heat exchange is eliminated in LES but difficult to avoid in the experiment. The difference in the air exchange rate at the roof level between the LES and wind tunnel data was no more than 5%, and the pollutant concentration distribution of the LES was almost the same as that of the experiments. This work emphasizes that the RANS method has limited ability to simulate flow and dispersion when the thermal effect is considered even at a reduced-scale, while LES can simulate the combined effects of incoming flow temperature stratification and local thermal effects. It is therefore suggested that if computing resources are limited and the temperature difference is not large, a steady-state calculation RANS can be used. Otherwise, LES must be performed.

A novel compact supercritical CO2 solar receiver based on impinging jet: Heat transfer performance and thermal stress analysis

The compact solar receiver can withstand high temperature and high pressure, which provides promising solutions for direct supercritical CO2 (S-CO2) solar receiver applications. However, it still suffers from local high temperature and large thermal stress due to the non-uniform heating boundary condition. The impinging jet method can significantly enhance the local heat transfer coefficient, holding significant potential in reducing the local high temperature of the compact S-CO2 receiver. Inspired by this, a novel design for a compact S-CO2 receiver using the impinging jet was proposed in this work. The heat transfer performance and stress behavior of the jet channel within the receiver were numerically investigated. The results showed that the jet channel has a significantly higher heat transfer performance than the rectangular channel, and the shorter flow path of the jet channel also effectively reduces the pressure loss. Meanwhile, the jet pattern significantly enhances the temperature uniformity, thereby reducing the thermal stress. In addition, increasing the channel aspect ratio improves the thermo-hydraulic performance, but increase the stress at the same time. The increase in the number of jet holes and the jet hole diameters not only enhance the thermo-hydraulic performance, but also reduce the stress of the jet channel.

Numerical simulation of keyhole-induced pores for TA15 in laser powder bed fusion (L-PBF)

In the complex laser powder bed fusion (L-PBF) process, the occurrence of pores is often triggered when localized temperatures of the materials exceed their boiling point, posing a significant impediment to the overall quality of manufactured parts. In this work, considering the thermophysical properties and latent heat of phase transformation of the material, the formation and evolution of keyholes and pores during the L-PBF single-track processing of TA15 titanium alloy was investigated using X-ray computed tomography (X-CT) and FLOW-3D finite volume analysis software coupled with multiphysics fields. The simulated molten pool characteristics generally agree with the experimental data, including internal pores The results showed that the evolution of keyholes is mainly attributed to surface tension and recoil pressure, the Marangoni flow and surface tension contributed to closed localized cooling regions on the keyhole walls to generate pores. Additionally, the Marangoni flow and buoyancy effects lead to pore motion within the molten pool. Furthermore, the laser energy density is inherently related to the total pore counts and the mean penetration depth of keyholes, respectively. Understanding the underlying physical mechanisms helps to optimize process parameters and reduce pores in L-PBF, ultimately enhancing the quality of the additively manufactured parts.

Quantifying tissue temperature changes induced by infrared neural stimulation: numerical simulation and MR thermometry.

Infrared neural stimulation (INS) delivered via short pulse trains is an innovative tool that has potential for us use for studying brain function and circuitry, brain machine interface, and clinical use. The prevailing mechanism for INS involves the conversion of light energy into thermal transients, leading to neuronal membrane depolarization. Due to the potential risks of thermal damage, it is crucial to ensure that the resulting local temperature increases are within non-damaging limits for brain tissues. Previous studies have estimated damage thresholds using histological methods and have modeled thermal effects based on peripheral nerves. However, additional quantitative measurements and modeling studies are needed for the central nervous system. Here, we performed 7 T MRI thermometry on ex vivo rat brains following the delivery of infrared pulse trains at five different intensities from 0.1-1.0 J/cm2 (each pulse train 1,875 nm, 25 us/pulse, 200 Hz, 0.5 s duration, delivered through 200 µm fiber). Additionally, we utilized the General BioHeat Transfer Model (GBHTM) to simulate local temperature changes in perfused brain tissues while delivering these laser energies to tissue (with optical parameters of human skin) via three different sizes of optical fibers at five energy intensities. The simulation results clearly demonstrate that a 0.5 second INS pulse train induces an increase followed by an immediate drop in temperature at stimulation offset. The delivery of multiple pulse trains with 2.5 s interstimulus interval (ISI) leads to rising temperatures that plateau. Both thermometry and modeling results show that, using parameters that are commonly used in biological applications (200 µm diameter fiber, 0.1-1.0 J/cm2), the final temperature increase at the end of the 60 sec stimuli duration does not exceed 1°C with stimulation values of 0.1-0.5 J/cm2 and does not exceed 2°C with stimulation values of up to 1.0 J/cm2. Thus, the maximum temperature rise is consistent with the thermal damage threshold reported in previous studies. This study provides a quantitative evaluation of the temperature changes induced by INS, suggesting that existing practices pose minimal major safety concerns for biological tissues.

Multimodal analysis of traction forces and the temperature dynamics of living cells with a diamond-embedded substrate.

Cells and tissues are constantly exposed to chemical and physical signals that regulate physiological and pathological processes. This study explores the integration of two biophysical methods: traction force microscopy (TFM) and optically detected magnetic resonance (ODMR) to concurrently assess cellular traction forces and the local relative temperature. We present a novel elastic substrate with embedded nitrogen-vacancy microdiamonds that facilitate ODMR-TFM measurements. Optimization efforts focused on minimizing sample illumination and experiment duration to mitigate biological perturbations. Our hybrid ODMR-TFM technique yields TFM maps and achieves approximately 1 K precision in relative temperature measurements. Our setup employs a simple wide-field fluorescence microscope with standard components, demonstrating the feasibility of the proposed technique in life science laboratories. By elucidating the physical aspects of cellular behavior beyond the existing methods, this approach opens avenues for a deeper understanding of cellular processes and may inspire the development of diverse biomedical applications.

Long-term plasma exposure of ITER-like W/Cu monoblocks with pre-damaged surfaces in EAST experiments

In the ITER and future fusion devices, W/Cu monoblocks will be used as divertor target which are exposed to both steady state heat load and transient heat flux. Especially, the transient heat flux up to 10 GW m−2 during plasma disruption, is expected to induce the shallow surface damages, such as melting, and even boiling of W/Cu monoblocks. Thus, the performance of damaged W/Cu monoblocks under subsequent long-term plasma discharges is a key concern that needs to be verified and tested on existing tokamaks. Since 2022, a new type of main limiter composed of ITER-like W/Cu monoblocks has been installed and tested in EAST. The surface of W/Cu monoblocks of the limiter was damaged by the transient heat flux during the early stages of plasma construction. Subsequently, they were subjected to long-term plasma discharges over 2600 shots in normal plasma discharge conditions. This circumstance conveniently facilitates the discussion of the performance of W/Cu monoblocks with damaged surfaces especially a melting edge with hill structure under prolonged exposure to plasma. In general, the shallow damage resulting from transient heat flux on W/Cu monoblocks appears to have minimal impact on the heat exhaust capacity under steady-state heat loads, as indicated by both experimental monitoring and numerical simulation results. However, shallow melting, leading to a change in surface structure and the formation of hills, could theoretically increase local temperatures, creating potential hot spots. This phenomenon requires further validation through dedicated experiments. Moreover, the brittleness of the near-surface layer may give rise to brittle destructions, such as cracks and even dust particles, posing an additional concern. These findings yield unique qualitative conclusions that can be referenced for ITER and other fusion devices.

Latitudinal variation in thermal performance of the common coral Pocillopora spp.

Understanding how tropical corals respond to temperatures is important to evaluating their capacity to persist in a warmer future. We studied the common Pacific coral Pocillopora over 44° of latitude, and used populations at three islands with different thermal regimes to compare their responses to temperature using thermal performance curves (TPCs) for respiration and gross photosynthesis. Corals were sampled in the local autumn from Moorea, Guam and Okinawa, where mean±s.d. annual seawater temperature is 28.0±0.9°C, 28.9±0.7°C and 25.1±3.4°C, respectively. TPCs for respiration were similar among latitudes, the thermal optimum (Topt) was above the local maximum temperature at all three islands, and maximum respiration was lowest at Okinawa. TPCs for gross photosynthesis were wider, implying greater thermal eurytopy, with a higher Topt in Moorea versus Guam and Okinawa. Topt was above the maximum temperature in Moorea, but was similar to daily temperatures over 13% of the year in Okinawa and 53% of the year in Guam. There was greater annual variation in daily temperatures in Okinawa than Guam or Moorea, which translated to large variation in the supply of metabolic energy and photosynthetically fixed carbon at higher latitudes. Despite these trends, the differences in TPCs for Pocillopora spp. were not profoundly different across latitudes, reducing the likelihood that populations of these corals could better match their phenotypes to future more extreme temperatures through migration. Any such response would place a premium on high metabolic plasticity and tolerance of large seasonal variations in energy budgets.

Thermo-chemical nonequilibrium effects on combustion characteristics of a transverse jet in the scramjet

As the Mach number increases, the local static temperature gradually approaches the characteristic gas vibration/dissociation temperature, and significant thermo-chemical relaxation processes occur. The thermo-chemical nonequilibrium phenomenona could affect the mixing and combustion process and become a factor that must be considered for scramjet design. In this paper, a large eddy simulation solver based on the two-temperature model is developed. The transfer terms between vibrational and trans-rotational energy are modeled by the Landau–Teller formulation and the vibrational-dissociation coupling is considered by adopting the Park model. Three sets of simulations based on the Hyshot Ⅱ engine configuration with different models were performed simultaneously to validate numerical methods and analyze results. The results reveal that the shock, cross-injection of fuel, and Prandtl-Meyer flow induce significant nonequilibrium regions. The vibration relaxation process in the jet mixing region is frozen, the vibration temperature is much higher than the trans-rotational temperature, and the extra energy is converted from the vibration mode to the trans-rotational mode, resulting in the increase of the trans-rotational temperature and the advance of auto-ignition in the nonequilibrium condition. Considering the vibration-dissociation coupling, the higher vibration temperature promotes dissociation. It inhibits the generation of active radicals in the ignition process, weakening the enhancement effect of nonequilibrium on auto-ignition. In the expanded nozzle, the concentrations of molecules and trans-rotational temperature in nonequilibrium cases are slightly lower than those in the equilibrium case due to the enhancement of dissociation.

Space-resolved electron density and temperature evaluation by x-ray pinhole camera method in an ECR plasma

X-ray emission characterization provides valuable insights about electron cyclotron resonance (ECR) plasmas. In principle, space-resolved spectroscopic techniques can be used to reveal spatial distributions of electron density and temperature. In the PANDORA (Plasma for Astrophysics, Nuclear Decay Observation, and Radiation for Archaeometry) project framework, and within the collaboration between the Atomki and INFN-LNS laboratories, we developed a high-resolution full-field x-ray pinhole setup. This setup incorporates advanced analysis techniques for single photon counted imaging in high dynamical range mode, enabling x-ray imaging and space-resolved spectroscopy at high spatial and energy resolution (560 μm and 242 eV @ 8.1 keV, respectively). Here, we introduce an innovative technique for quantitatively evaluating the local electron density and temperature of plasma, as the first application of such a method in an ECR setup. Specifically, we examine an argon plasma heated by 200 W microwave power at 14 GHz. Our analysis includes a retrospective comparison with past x-ray data collected from other ECR ion source setups. Our findings clearly reveal the formation of a plasmoid–halo structure within the plasma chamber, characterized by a dense and hot plasma almost totally enclosed inside the ECR magnetic iso-surface (the plasmoid). This plasmoid exhibits nearly uniform distribution of electron density and temperature, with only gentle gradients of both the parameters toward its edges. Inside the halo, x-ray emission is minimal or even negligible. Notably, cusp structures correspond to magnetic branches where deconfined electrons impinge upon the plasma chamber walls and endplates. The average values of temperature and density measured inside the plasmoid are 12.44±1.84 keV and (1.66±0.15)×1017 m−3, respectively.

Modeling high‐intensity ultrasound to enhance shrimp (Penaeus vannamei) brining without compromising crucial purchase attributes

AbstractTraditional brining methods, such as immersion, are time‐consuming and affect the quality of the food product. Thus, high‐intensity ultrasound (HIUS) has been studied as a brining‐assisted non‐thermal technology. However, this approach to shrimp and the assessment of the individual and combined effects of HIUS parameters, for example, time (t), power (P), and salt concentration (SC), is a knowledge gap. This study aimed to model HIUS‐brining for improving salt diffusion and water properties while maintaining relevant purchase attributes closer to fresh shrimp (Penaeus vannamei) quality. Our findings suggest HIUS improves salt diffusion, decreasing Aw and enhancing water‐holding capacity (WHC). Instead, the increased P reduced hardness and enhanced whiteness. HIUS‐brining (22.02 min/267.89 W/6.68%) maximized Na+ (2.58%) and WHC (86.31%), minimized Aw (.92), and retained hardness (71.07 N) and whiteness (55.14) close to freshness. Therefore, it is possible to employ HIUS in the shrimp brine to improve salt diffusion without damaging physicochemical attributes.Practical applicationsDespite traditional methods for seafood brining being considered effective, they are time‐consuming, taking hours to reach the desirable moisture value. High‐intensity ultrasound (HIUS) is an emerging non‐thermal technology recently explored as a brining technology for animal‐origin food, such as meat. The cavitation induced by HIUS generates gas microbubbles. The implosion increases local temperature and pressure and generates microjets, facilitating the mass transfer (sponge effect) and salt diffusion in the muscle tissues. However, the cavitation mechanism also releases free radicals, resulting in physicochemical alterations during processing, such as damage to color and texture. The present research contributes to providing a better understanding of the application and optimization of HIUS to accelerate the shrimp brining process. The findings herein are promising for the industrial utilization of sonication to obtain brined products without damaging the quality attributes of shrimp.

Multiobjective Optimization of Rotodynamic Blood Pumps: The Use Case of a Cavopulmonary Assist Device.

Comprehensive optimization of rotodynamic blood pumps (RBPs) requires the consideration of three partially conflicting objectives: size, hemocompatibility, and motor efficiency. Optimizing these individual objectives independently, the potential of multiobjective optimizations often remains untapped. This study aimed at the multiobjective optimization of an RBP for cavopulmonary support accounting for all three objectives simultaneously. Hydraulic and electromagnetic design spaces were characterized using computational fluid dynamics and computational electromagnetics, respectively. Design variables included secondary flow gap widths, impeller diameters, and stator heights. The size objective encompassed the RBP widths and heights, the hemocompatibility objective was a weighted composite measure of well-established metrics, and the motor objective was determined by motor losses. Multiobjective optimization was performed through Pareto analysis. 81 designs were considered, and 21 Pareto-optimal designs were identified. The Pareto analysis indicated that hemocompatibility performance could be improved by 72.4% with a concomitant 1.5% reduction in the baseline pump volume. This, however, entailed an increase in motor losses by 0.2 W, while still meeting design requirements, with maximum local temperature rises remaining below 0.4 K. The multiobjective optimization led to a Pareto front, demonstrating the feasibility to improve hemocompatibility at reduced pump volume, however, at the cost of a diminished yet still acceptable motor performance.

Solar-enhanced lithium extraction with self-sustaining water recycling from salt-lake brines

Lithium is an emerging strategic resource for modern energy transformation toward electrification and decarbonization. However, current mainstream direct lithium extraction technology via adsorption suffers from sluggish kinetics and intensive water usage, especially in arid/semiarid and cold salt-lake regions (natural land brines). Herein, an efficient proof-of-concept integrated solar microevaporator system is developed to realize synergetic solar-enhanced lithium recovery and water footprint management from hypersaline salt-lake brines. The 98% solar energy harvesting efficiency of the solar microevaporator system, elevating its local temperature, greatly promotes the endothermic Li+ extraction process and solar steam generation. Benefiting from the photothermal effect, enhanced water flux, and enriched local Li+ supply in nanoconfined space, a double-enhanced Li+ recovery capacity was delivered (increase from 12.4 to 28.7 mg g-1) under one sun, and adsorption kinetics rate (saturated within 6 h) also reached twice of that at 280 K (salt-lake temperature). Additionally, the self-assembly rotation feature endows the microevaporator system with distinct self-cleaning desalination ability, achieving near 100% water recovery from hypersaline brines for further self-sufficient Li+ elution. Outdoor comprehensive solar-powered experiment verified the feasibility of basically stable lithium recovery ability (>8 mg g-1) directly from natural hypersaline salt-lake brines with self-sustaining water recycling for Li+ elution (440 m3 water recovery per ton Li2CO3). This work offers an integrated solution for sustainable lithium recovery with near zero water/carbon consumption toward carbon neutrality.

Experimental observations of the onset of unsteadiness for buoyant airflow along smooth and rough vertical isothermal walls

ABSTRACT The buoyant airflow along a vertical isothermal wall, under conditions close to transitional, is studied. The schlieren technique and miniature thermocouples are employed for qualitative (flow unsteadiness) and quantitative (heat transfer coefficient and local air temperature) observations. For the smooth surface, the phenomena are found to be sensitive to the enclosure configuration surrounding the plate. Roughening the heated surface with staggered rib segments of proper dimensions leads to increased heat transfer, ascribed to the onset of unsteadiness close to the segments’ edges, together with a better redistribution of the flow thanks to a favorable hydrodynamic interaction between fluid and protrusions.