Local Population Research Articles

Study on Spatialization and Spatial Pattern of Population Based on Multi-Source Data—A Case Study of the Urban Agglomeration on the North Slope of Tianshan Mountain in Xinjiang, China

The urban agglomeration on the north slope of the Tianshan Mountains is a pivotal place in Western China; it is essential for the economic growth of Xinjiang and acts as a critical bridge between China’s interior and the Asia–Europe continent. Due to unique natural conditions, the local population distribution exhibits distinct regional characteristics. This study employs the spatial lag model (SLM) from conventional spatial analysis and the random forest model (RFM) from contemporary machine learning techniques. It integrates traditional geographic data, including land cover data and nighttime light data, with geographical big data, such as POI (points of interest) and OSM (OpenStreetMap), to build a comprehensive indicator database. Subsequently, it simulates the spatial population distribution within the urban agglomeration on the northern slopes of the Tianshan Mountains in 2020. The accuracy of the results is then compared and assessed against the accuracy of other available population raster datasets, and the spatial distribution pattern in 2020 is analyzed. The findings reveal the following: (1) The result of SLM, combined with multi-source data, predicts the population distribution as a relatively uniform and nearly circular structure, with minimal spatial differentiation. (2) The result of RFM, employing multi-source data, better captures the spatial population distribution, resulting in irregular boundaries that are indicative of strong spatial heterogeneity. (3) Both models demonstrate superior accuracy in simulating population distribution. The spatial lag model’s accuracy surpasses that of the GHS and GPW datasets, albeit still trailing behind WorldPop and LandScan. Meanwhile, the random forest model significantly outperforms the four aforementioned population raster datasets. (4) The population spatial pattern in the urban agglomeration on the north slope of the Tianshan Mountains predominantly consists of four distinct circles, illustrating a “one axis, one center, and multiple focal points” distribution characteristic. Combining the random forest model with geographic big data for spatialized population simulation offers robust scientific validity and practicality. It holds potential for broader application within the urban agglomeration on the Tianshan Mountains and across Xinjiang. This study can offer insights for studies on regional population spatial distributions and inform sustainable development strategies for cities and their populations.

Morphological characterization and molecular marker-assisted selection for resistance to Tobacco mosaic virus (TMV) and Tomato spotted wilt virus (TSWV) in S2 population of capia pepper (Capsicum annuum L.)

AbstractTMV (Tobacco mosaic virus) and TSWV (Tomato spotted wilt virus) are the most common virus diseases that causes loss of productivity in pepper cultivation. The most effective method in the fight against viral diseases is the use of resistant cultivars. This study was conducted to determine the similarities and differences of 120 Capia pepper lines in the S2 stage, consisted of local populations, standard and hybrid cultivars, in terms of morphological variation and to determine the resistance levels of the lines to TSWV and TMV. As a result of molecular analysis, genotypes 34, 35, 36, 46, 47, 48, 84, and 85 were found to be homozygous resistant to L4 allele and the Tsw gene. Cluster analysis and principal component analysis (PCA) were applied to determine the relationship between the lines determined as a result of single plant selection. A dendrogram was prepared to evaluate morphological similarity between the lines. In the cluster analysis, 10 groups were identified based on 25 variables. The PCA explained 69.9% of the total variation based on 10 PC axes. At the end of the study, morphological variability was found high among the pepper lines. This evaluation of plant trait variability can assist geneticists and breeders to identify populations with desirable characteristics for inclusion in pepper breeding programs. In addition, the levels of resistance to these two diseases are crucial for breeding programs aimed at developing cultivars resistant to diseases.

An Examination of the Ways in Which Transdisciplinary Research Could Be Used to Incentivize Local Communities to Combat the Illegal Wildlife Trade

The illegal wildlife trade (IWT) is currently one of the most critical conservation concerns, given its direct impact on biodiversity loss, endangering local ecosystems, and adding pressure to all species at a point when they face dangers like deforestation and mass extinctions. This industry also significantly impacts local communities, many of which are compelled to engage in it as a result of their precarious socioeconomic conditions. While effective countermeasures to this global issue have been identified, successful implementation of these countermeasures require diverse disciplines and collaborators. This paper argues that a transdisciplinary approach that converges knowledge and skills from social and socioecological fields of study is required to develop strategies that effectively incentivize communities to combat the IWT. This is true because A) at the social level, criminal justice is needed for the retraining and participation in law enforcement efforts to mitigate support for poaching; B) at the socio-ecological level, environmental economics and ecosystem management are needed for the validation of community assets and profitable management of local wildlife; and C) ecology and business administration are needed for the implementation of conservation initiatives like ecotourism. This paper not only presents the implementation of a transdisciplinary approach but also details the most important disciplines needed, provides a review of the correlation between this industry and the locals who live in close proximity to wildlife and conservation areas, and proposes workable recommendations to supporting initiatives that combat the IWT and serve as pillars for sustainable action. Without adopting and reinforcing the position argued for in this research, the IWT would continue to pose a threat to local ecosystems, populations, and economies. This is a major risk to global sustainability and will exacerbate the loss of biodiversity that is already recognized as an imminent threat by the United Nations Sustainable Development Goals.

A comprehensive analysis of uncertainties in warm rain parameterizations in climate models based on in situ measurements

Abstract Because of the coarse grid size of Earth system models (ESM), representing warm-rain processes in ESMs is a challenging task involving multiple sources of uncertainty. Previous studies evaluated warm-rain parameterizations mainly according to their performance in emulating collision-coalescence rates for local droplet populations over a short period of a few seconds. The representativeness of these local process rates comes into question when applied in ESMs for grid sizes on the order of 100 kilometers and time steps on the order of 20-30 minutes. We evaluate several widely used warm-rain parameterizations in ESM application scenarios. In the comparison of local and instantaneous autoconversion rates, the two parameterization schemes based on numerical fitting to stochastic collection equation (SCE) results perform best. However, because of Jessen’s inequality, their performance deteriorates when grid-mean, instead of locally-resolved, cloud properties are used in their simulations. In contrast, the effect of Jessen’s inequality partly cancels the overestimation problem of two semi-analytical schemes, leading to an improvement in the ESM-like comparison. In the assessment of uncertainty due to the large time step of ESMs, it is found that the rain-water tendency simulated by the SCE is roughly linear for time steps smaller than 10 minutes, but the nonlinearity effect becomes significant for larger time steps, leading to errors up to a factor of 4 for a time step of 20 minutes. After considering all uncertainties, the grid-mean and time-averaged rain-water tendency based on the parameterization schemes are mostly within a factor of 4 of the local benchmark results simulated by SCE.

Population-specific climate sensitive top height curves and their applications to assisted migration

AbstractGrowth and yield (G&Y) of forest plantations can be significantly impacted by maladaptation resulting from climate change, and assisted migration has been proposed to mitigate these impacts by restoring populations to their historic climates. However, genecology models currently used for guiding assisted migration do not account for impacts of climate change on cumulative growth and assume that responses of forest population to climate do not change with age. Using provenance trial data for interior lodgepole pine (Pinus contorta subsp. latifolia Douglas) and white spruce (Picea glauca (Moench) Voss) in western Canada, we integrated Universal Response Functions, representing the relationship of population performance with their provenance and site climates, into top height curves in a G&Y model (Growth and Yield Projection System, GYPSY) to develop population-specific climate sensitive top height curves for both species. These new models can estimate the impact of climate change on top height of local populations and populations from a range of provenances to help guide assisted migration. Our findings reveal that climate change is expected to have varying effects on forest productivity across the landscape, with some areas projected to experience a slight increase in productivity by the 2050s, while the remainder are projected to face a significant decline in productivity for both species. Adoption of assisted migration, however, with the optimal populations selected was projected to maintain and even improve productivity at the provincial scale. The findings of this study provide a novel approach to incorporating assisted migration approaches into forest management to mitigate the negative impacts of climate change.

Stakeholder perceptions in mangrove management in the Jaffna Peninsula, Sri Lanka

Mangroves are recognised as social-ecological systems where ecological dimensions constanty interact with human dimensions. In the Jaffna Peninsula of Sri Lanka, mangroves constitute the primary forest type. However, a destructive civil war spanning over 25 years, heavily affected the local vegetation and local inhabitants. Large patches of mangrove forests were damaged and remained inaccessible for a considerable time, compelling most of the population to temporarily abandon their land. This study aimed to investigate the main mangrove goods and services that the local population benefits from and gather opinions of mangrove management stakeholders regarding mangrove conservation in the Jaffna Peninsula through a mixed methods approach. Ethnobiological surveys were conducted with coastal communities, along with Q methodology, expert opinion surveys and additional semi-structured interviews with mangrove management stakeholders. Ethnobiological surveys revealed a significant distancing of local communities from mangrove goods and services. The Q methodology identified three discourses: community-oriented, government-oriented, and mangrove conservation oriented. Expert opinion surveys highlighted encroachment and pollution as major threats to mangroves. Issues raised in the semi structured interviews include challenges regarding land ownership permits during and after the war, weak interactions among different stakeholders with overlapping jurisdiction, failed replantation efforts and scarcity of scientific data for mangrove management. Addressing these issues is crucial not only for fostering effective mangrove management and conservation in the Jaffna Peninsula but also forpotentially benifittingother districts in Sri Lanka and beyond.

Potential importance of vegetative spread and fragment regeneration for invasiveness of Clematis vitalba

AbstractIdentifying characteristics of invasive species or growth forms that facilitate their range expansion is critical for management. Clematis vitalba L. (old man's beard) is an invasive temperate liana in many areas of its introduction, yet its seedlings do not thrive in circumstances where resources are limited. Although some lianas in both tropical and temperate climates have been shown to spread by clonal stems along the ground, the bulk of previous research on C. vitalba reproduction has focused largely on aspects of seed ecology. The vegetative growth of the species is poorly understood. The first objective of our study was to evaluate the use of vegetative spread by C. vitalba as a means of local dispersal and population growth. We excavated ten 1‐m2 plots in infested riparian zones and found an extensive, branching network of creeping stems, both above and below ground. Our second objective was to test the ability of C. vitalba stem fragments to act as vegetative propagules. After 4 months, ~50% of two‐node fragments had regenerated, from both creeping and climbing stems. These studies help explain how a temperate liana forms populations and dominate ecological communities. The findings provide good evidence that C. vitalba may rely quite heavily on asexual reproduction. In addition, the results document liana stem phenotypic plasticity; fragmented climbing stems are just as likely as fragmented creeping stems to reprogram shoot tissue systems, generate roots and regrow as independent plants.

Application of GIS & RS in Rainwater Harvesting for an Arid Region

In dry areas with variable rainfall, water shortages severely affect the livelihoods of local populations. Rainwater harvesting from land sites and roof-tops is a readily available solution to this problem. This study presents a GIS & RS-based methodology to identify potential land sites and roof-top rainwater harvesting potential using easily obtainable and freely available data. Slope, land cover, soil, and drainage maps were used to identify suitable rainwater harvesting land sites, which were further analyzed for surface runoff using the curve number method. This research also incorporated obtainable socio-economic factors in identifying the suitable locations of dams considering the implementation stage. Based on the proposed criteria, 44 suitable locations for dams were identified and validated using a validation map and Google Earth images. CROPWAT model analysis revealed that paddy water demand in Batticaloa would increase threefold if all available land for paddy cultivation was utilized. Therefore, abandoned lands can be utilized by erecting dams at those identified locations. Analysis of Google Earth images also revealed that roof rainwater harvesting would be sufficient to meet the basic water demand in the area. This study demonstrates that rainwater harvesting can be an effective strategy for addressing water scarcity in dry areas.

Food ethnobotany of forest resource in the high-altitude Himalaya Mountains: Enhancing the food sovereignty of ethnic groups

The vital knowledge of traditional foraging techniques used in indigenous peoples' cuisines may be preserved through gastronomical field studies before it is lost forever. Certain plants are appreciated for their gastronomic, social, economic and ecological importance in the High Himalaya because they play such a significant role in the daily life of the local indigenous populations. To determine the plant cultural indicators for each ethnic group, the data were analyzed using an indicator species analysis. Semi-structured interviews of 167 participants, focus group discussion, and field observations were used to gather information from February 2019 to August 2022 for a comprehensive and systematic gastronomical survey. Across four ethnic groups, a total of (N = 99) wild edible plant species and (N = 9) fungi species from 38 families were documented. Tender leaves were the most commonly used, while tubers were the least commonly used. The majority of the species reported were used as vegetables, followed by species used as fruits and herbal tea. For the first time, we examined cross-cultural similarity and dissimilarity for gastronomic usage: vegetables and savoring plants,fruits, and herbal tea across the cultures studied from the perspective of food ethnobotany. We discovered a clear difference in how different cultures used forest resources, with Gujjar and Pahari showing the most species similarity. This is because these ethic groups are culturally linked with one another and share a common social structure, geography, and language. We calculated plant cultural markers for each species, and 19 of them had significant p-values among the four ethnic groups. The findings revealed a positive relationship between the Gujjar and Pahari ethnic groups and the gastronomical indicator values, while the Kashmiri ethnic group had a negative relationship. The Kashmiri ethnic group experienced the loss of traditional knowledge because of the economic transition that caused people to prefer purchasing vegetables from the market rather than foraging for them in the wild. Traditional knowledge was also dwindling between the Gujjar and Pahari ethnic groups because of social changes brought on by developmental activities that changed their way of life. The identified plant cultural markers were significant to local residents and frequently had adaptations to extremely harsh climatic and environmental conditions. Our finding that 47% of species had market value suggests that these species have a sizable market demand and a promising economic value. They have the potential to boost food security, local community sovereignty, and people's living standards. Food production systems may become more resilient and sustainable by incorporating these indicator species into conventional agriculture. The current study raises awareness about forest resources and enables ethnic groups to live in a natural environment without food scarcity.

Infrastructural Development under BADP in Dibang Valley District of Arunachal Pradesh

Border Area Development Programme (BADP) was started in western international border with Pakistan, during the Seventh five-year Plan (1986-87) with the twin objectives of balanced development of sensitive border areas through adequate provision of infrastructure facilities and promotion of a sense of security amongst the local population. However, in the case of Arunachal Pradesh, BADP was first introduced in 1997-98, allocating Rs 4.00 crores for implementation across 33 schemes. This study made an attempt to investigate the overview infrastructure development status of BADP in Arunachal Pradesh. Further, the purpose of the study is to investigate the attitudes towards the assets created under BADP. The study is descriptive and analytical in nature.For the present study, Stratified Random Sampling under Probability Sampling Techniques was used. 40 samples were randomly taken from study areas

Mind the Gap: Conflicts in the Implementation of Kenya’s Lake Turkana Wind Power Project

Renewable energy projects are increasingly being implemented at scale to meet global climate goals, often targeting lands on the margins of the state and affecting the livelihoods of Indigenous or marginalized populations. This article argues a need for project-developers, investors and rights advocates to consider the potentially significant ‘gap’ between their expectations that the rights of local populations will be settled at the start of a particular investment and the conflicts over rights, recognition and benefits that emerge during implementation that risk derailing investments. This is particularly relevant for renewable investments, as their claims to global and national benefits divert attention from their local impacts. Empirically, this is explored through the case of the Lake Turkana Wind Power project in Kenya. Based on interviews and literature review, the article examines the relations between the key stakeholders in this project by acknowledging their various ‘ways of seeing’ rights. Ruling elites often see rights as settled once they have been written into law and investors assume that rights have been dealt with at the project’s start, but local populations typically begin exploring their rights following project-induced changes. The interaction of stakeholders with such diverse views has important implications for the practice of human rights in the context of renewable energy investments.

Communities’ Perceptions and Coping Strategies to Flood Hazard in a Peri-Urban Catchment: The Case Study of the Zio River Basin, Togo, West Africa

Climate and land use changes have exacerbated the frequency and intensity of floods in West Africa. In Togo, the communities of the Zio river sub-basin are regularly affected by flood hazard with severe socio-economic consequences. The main objective of this article is to contribute to the improvement of the resilience of these populations through a better understanding of their perceptions and coping strategies to flood hazards. To achieve this goal, a mixed method consisting of household surveys, focus groups and direct observation is used. In addition, the data collected at the household level focused on the perceptions of the flood (origin and cause), the socio-economic impacts as well as the coping strategies. The results indicate that more than 80% of the households are affected by floods and the main negative consequences are the destruction of houses (40.8%), and interruption of socio-economic activities (58.4%). In addition, the efforts to cope with the severe impacts of floods include embankment (71.6%), storage on occasional shelves (52.3%), digging ditches (26.6% and the construction of cement houses with fairly raised foundations (13.1%). This study shows that is important to integrate indigenous knowledge and local population’s opinions in the flood risk management plans in order to increase their resilience.

Religion and higher education migrants’ acculturation orientation

ABSTRACT Muslims may not experience integration or assimilation in European countries, as they have certain values regarding hijab, eating restrictions, and lifestyle. They may therefore face more challenges than other migrants. With the insight that religiosity may have an impact on migrants’ national and/or ethnic identities, we look at the role of religion in acculturation. The study investigated emerging patterns and challenges in sociocultural adaptation processes, including host-community interactions with (Iranian) migrants and Iranian international PhD students’ future intentions. Positive evaluations of the attitudes of Spaniards towards Iranians are thought to improve the drive to seek out intergroup contact and facilitate integration or assimilation in Spain. The paper’s key finding is that religion has an impact on Iranian international students. It is possible to imagine religion as a unifying factor that binds many migrant populations under a single ethnic identity. When regarded as a threat to the migrants’ ethnic identity, it also appears to create social distance between the migrants and the local population. The results of this study can be used to address factors that threaten successful acculturation and boost those that encourage sociocultural adaptation and learning the local language.

Complete Blood Count Reference Intervals for Children Aged Less Than 1 to 12 Years in the Northern Region of Ghana.

Reliable laboratory diagnostic results are key for evaluating and improving children's health. To interpret these results, child-specific reference intervals (RIs), which account for constant biological changes and physiological development with sex and age, are required, as recommended by the Clinical and Laboratory Standards Institute (CLSI). This study presents age- and sex-specific reference intervals for complete blood count (CBC) parameters in children (<1-12 years old) in the Northern Region of Ghana. In this cross-sectional study, 600 healthy children from randomly sampled schools in Tamale (the Northern Region) were recruited and screened. Data from 388 eligible children were used to nonparametrically determine the reference intervals of CBC parameters at the 2.5th and 97.5th percentiles. The CBC reference intervals were compared for variations in sex and age groups using the Wilcoxon rank-sum test. There were no statistically significant differences in most CBC parameters by sex (RBC, Hb, HCT, MCH, RDW (CV/SD), WBC, LYM#, MON#(%) NEU#(%), EOS#(%), and BAS#(%); p > 0.05) and age group (RBC, MCV, RDW (CV/SD), WBC, LYM#, MON#(%) NEU#(%), EOS#(%), and BAS%; p > 0.05). However, there were observable differences between this locally established CBC reference interval and that used for children at Tamale Teaching Hospital (manufacturer's RIs). This study emphasises the importance of determining reference intervals representative of the local child population and incorporating them into the current reporting system of laboratories in the Northern Region to ensure the provision of effective and efficient healthcare services.

ПЕРВЫЕ НАЦИОНАЛЬНЫЕ МЕДИЦИНСКИЕ КАДРЫ КАБАРДЫ И БАЛКАРИИ

сurrently, the study of the historical stages of the formation and development of medical personnel and the entire health care systemas a whole is one of the most relevant areas in the course of higher medical education. The significance of the problem makes us turn to the lessons of the past, namely, the history of the appearance of the first doctors, whose names and experience formed the basis for the formation and development of healthcare. The article attempts to restore the names of unfairly "forgotten" people who devoted themselves entirely to the cause of healing, as well as the history of the first national medical personnel in the region and their contribution to the prevention and treatment of the local population of the Nalchik district. The article is based on the biographical data carefully collected in the Archive Service of the Kabardino-Balkar Republic and other sources of the first well - known regional doctors from the indigenous inhabitants of Kabardino-Balkaria, as well as their contribution to the development of medical services in the region, which makes the work unique. The selfless work of the first doctors shows the history of the formation and development of traditional medicine and all health care in the Nalchik district of the Terek region in the pre-revolutionary period. Studying the history of regional healthcare development helps to better understand and evaluate positive experiences, and to anticipate the main directionsof its subsequent development.

Molecular gas scaling relations for local star-forming galaxies in the low-M_* regime

We derived molecular gas fractions ($f_ mol =M_ mol /M_*$) and depletion times ($ mol = M_ mol SFR $) for 353 galaxies representative of the local star-forming population with $10^ \,M_ &lt; M_* &lt; \,M_ drawn from the ALLSMOG and xCOLDGASS surveys of CO(2-1) and CO(1-0) line emission. By adding constraints from low-mass galaxies and upper limits for CO non-detections, we find the median molecular gas fraction of the local star-forming population to be constant at $ f_ mol $, challenging previous reports of increased molecular gas fractions in low-mass galaxies. Above $M_* \,M_ we find the $f_ mol $ versus $M_*$ relation to be sensitive to the selection criteria for star-forming galaxies. We tested the robustness of our results against different prescriptions for the CO-to-H$_2$ conversion factor and different selection criteria for star-forming galaxies. The depletion timescale $ mol $ weakly depends on $M_*$, following a power law with a best-fit slope of . This suggests that small variations in specific star formation rate ($ sSFR=SFR /M_*$) across the local main sequence of star-forming galaxies with $M_* &lt; 10^ \,M_ are mainly driven by differences in the efficiency of converting the available molecular gas into stars. We tested these results against a possible dependence of $f_ mol $ and $ mol $ on the surrounding (group) environment of the targets by splitting them into centrals, satellites, and isolated galaxies, and find no significant variation between these populations. We conclude that the group environment is unlikely to have a large systematic effect on the molecular gas content of star-forming galaxies in the local Universe.

Mosquitex, a new tool for capturing Aedes (Stegomyia) aegypti (Linnaeus, 1762) (Diptera: Culicidae)

The species Aedes (Stegomyia) aegypti (Linnaeus, 1762) (Diptera: Culicidae) is of great importance for human health, as it is responsible for the transmission of viruses that can cause dengue, chikungunya, zika and urban yellow fever. The proposal of this study is to test the efficiency of a new trap model in capturing and trapping Ae. aegypti based on favoring the insect's ecology. This trap model was analyzed regarding the attractiveness for egg-laying, and the trapping of larvae and consequently the adults. The tests were carried out using white traps (original version) and black traps (adapted from the original), both in field and laboratory conditions. In the field, the black traps showed 100% effectiveness compared to white traps, showing more positive results for the attractiveness of Ae. aegypti mosquito and adult imprisonment. According to the results for this trap model, from both test in the field and in the laboratory, it was concluded that this new product is effective in capturing Ae. aegypti and it guarantees mosquito trapping safety, also low-cost production, practicality, logistics and possibility of its use by the local population. After the validation and effectiveness of the trap “drinking-fountain like”, the definitive trap called Mosquitex was developed, which is brand new for this mosquito, with patent registration INPI - BR2020190112226 - 2019, and with the possibility of assisting in the control and monitoring of Ae. aegypti in urban areas.

Winter-ground microhabitat use by differently coloured phenotypes affects return rate in a long-distance migratory bird.

Migratory bird populations are declining globally at alarming rates. Non-breeding site conditions affect breeding populations, but generalising non-breeding habitat conditions over large spatial regions cannot address potential fine-scale differences across landscapes or local populations. Plumage characteristics can mediate the effects of environmental conditions on individual fitness. However, whether different phenotypes use distinctive non-breeding sites, and whether they respond to non-breeding site conditions differently remains largely unknown. Stable isotopes (δ13C, δ15N, δ2H) of inert tissues are useful to infer habitat characteristics and geographic origins where those tissues were grown. We collected winter-grown feathers from pied flycatchers (Ficedula hypoleuca) on their breeding grounds over several years from males whose dorsal plumage colouration ranged continuously from brown to black and assessed their stable isotope values as proxies of local habitat conditions. Based on feather δ2H profiles we found that browner males spent their non-breeding season in drier habitats than black males. Assignment to origin analysis shows potential regional non-breeding ground separation between differently coloured males. High within-individual repeatability of both δ13C and δ15N indicate the pied flycatcher males return yearly to similar areas. Blacker males were more likely to return to the breeding grounds after dry years compared with brown males. The opposite was found in wet years. Our study demonstrates that different phenotypes are exposed to different non-breeding site conditions which can differentially affect individual survivorship. This has important ramifications for population dynamics under predicted climate change scenarios where especially brown phenotype pied flycatcher males may be under a risk of decreasing.

The contribution of cannabis use to the increased psychosis risk among minority ethnic groups in Europe.

We examined whether cannabis use contributes to the increased risk of psychotic disorder for non-western minorities in Europe. We used data from the EU-GEI study (collected at sites in Spain, Italy, France, the United Kingdom, and the Netherlands) on 825 first-episode patients and 1026 controls. We estimated the odds ratio (OR) of psychotic disorder for several groups of migrants compared with the local reference population, without and with adjustment for measures of cannabis use. The OR of psychotic disorder for non-western minorities, adjusted for age, sex, and recruitment area, was 1.80 (95% CI 1.39-2.33). Further adjustment of this OR for frequency of cannabis use had a minimal effect: OR = 1.81 (95% CI 1.38-2.37). The same applied to adjustment for frequency of use of high-potency cannabis. Likewise, adjustments of ORs for most sub-groups of non-western countries had a minimal effect. There were two exceptions. For the Black Caribbean group in London, after adjustment for frequency of use of high-potency cannabis the OR decreased from 2.45 (95% CI 1.25-4.79) to 1.61 (95% CI 0.74-3.51). Similarly, the OR for Surinamese and Dutch Antillean individuals in Amsterdam decreased after adjustment for daily use: from 2.57 (95% CI 1.07-6.15) to 1.67 (95% CI 0.62-4.53). The contribution of cannabis use to the excess risk of psychotic disorder for non-western minorities was small. However, some evidence of an effect was found for people of Black Caribbean heritage in London and for those of Surinamese and Dutch Antillean heritage in Amsterdam.

Treatment outcome of elderly patients (≥ 78 years) with head and neck squamous cell carcinoma: A single center experience.

Patients older than the expected age of the local population generally have limited life expectancy. The optimal treatment approach for very elderly patients with head and neck cancer remains uncertain. This study retrospectively analyzed patients over 78 years old, the expected age in 2019 for Chinese individuals, who underwent treatment for head and neck cancer at a tertiary cancer center in China. The study compared the overall survival rates among different treatment groups. The findings revealed that among patients eligible for surgery, radical resection yielded better outcomes compared to radiotherapy-based treatments, with a hazard ratio of 0.362 (95% CI 0.160-0.819, P = 0.015). Among patients who received radiotherapy, those who received a total dose exceeding 60 Gy had a significantly longer survival compared to those who received palliative doses, with median survival time of 31 months versus 14 months (P = 0.003). Among 78 patients who underwent conventional fractionated radiotherapy (CFRT), 15 patients (19.23%) experienced unscheduled treatment breaks with a median duration of 12 days. However, these treatment breaks did not appear to impact survival (P > 0.1). The study also suggested that altered fractionated radiotherapy, including hypofractionated radiotherapy (hypo-RT), could be a viable alternative to CFRT, offering similar survival outcomes with reduced treatment duration. In conclusion, eligible patients should be treated with curative intent, even if they are older than the expected age of the local population. When radiotherapy is indicated, altered fractionation, particularly hypo-RT, may be a favorable option to consider.