The traditional real-time load warning method for distribution transformers has problems such as low recall rate, low warning accuracy, and long warning time, which may lead to potential equipment failures or overload situations not being detected and dealt with in a timely manner, increasing the safety risk of transformer operation and potentially causing safety issues such as equipment damage, fire, or power outage. Therefore, a real-time early warning method of distribution transformer load considering meteorological factor data is designed. The meteorological factor data are collected by the light sensor, humidity sensor, temperature sensor and rainfall sensor, and the load data collection architecture is built by the load monitor, central master station and maintenance station to realize the load data collection of the distribution transformer. The K-nearest neighbor (KNN) method is used to process the missing values of the data, and the LOF algorithm is used to determine the local outliers and eliminate the outliers in the data set to achieve data cleaning. Considering the load loss, hot spot temperature and meteorological factors of the distribution transformer, an early warning model is built, and the cleaned data are input into the model to realize Real-time early warning of the distribution transformer load. The experimental results show that the recall rate of this method varies from 95% to 97%, the accuracy rate of early warning is always above 94%, and the maximum value of early warning time is 0.63s. Having good early warning ability.