Local Manufacturing Research Articles

Pengaruh Promosi Word of Mouth, Brand Image, dan Brand Ambassador Terhadap Keputusan Pembelian Skincare Azarine di Stuffbyms Kota Semarang

The skincare industry in Indonesia is growing rapidly, with increasing competition between local and international manufacturers. This study aims to analyse the effect of Word of Mouth Promotion, Brand Image, and Brand Ambassador on purchasing decisions for Azarine skincare products at Stuffbyms Semarang City. Quantitative methods are used with questionnaires distributed to 83 respondents. The F test results show that the three independent variables simultaneously have a significant effect on purchasing decisions. The t test shows that Word of Mouth Promotion, Brand Image, and Brand Ambassador each have a positive and significant influence on purchasing decisions with a significance value of each below 0.05. The coefficient of determination (Adjusted R²) of 0.691 indicates that 69.1% of the variation in purchasing decisions can be explained by these variables. These findings provide important insights for Azarine's marketing strategy in the face of beauty industry competition.

RECYCLING OF LITHIUM ION BATTERIES: THE BLACK SPOT OF THE GREEN DEAL

Progress towards a decarbonized economy is dependent on the development of energy storage devices enabling the deployment of new strategies in the transport and energy sectors. Lithium-Ion Batteries (LIBs) play a key role in facilitating the shift from fossil fuels to renewables based on ubiquitous sources of decentralized energy. However, the rapidly increasing demand for batteries has generated environmental concerns regarding recycling, and raw materials depletion and exhaustion. Moreover, the level of extraction and processing of battery raw materials from local resources is almost negligible, inducing geopolitical concerns regarding potential threats to production and the stability of local manufactures. Finally, the storage and processing of hazardous wastes remains a difficult challenge in the circular economy concept. Recycling, therefore, is beneficial to the environment and has a high economic value via strengthening local supply chains. This work presents an alternative, comprehensive, and holistic review of LIB recycling technologies; from traditional metallurgy strategies to innovative, direct recycling methods and pioneering in-production and design-for-recycling approaches. It identifies new directions for making recycling efficient and techno-economically profitable and sustainable - including the vital role of robotics, artificial intelligence, and machine learning. Keywords: Lithium Ion Batteries, Recycling, Design for Recycling, In-production Recycling, Artificial Intelligence

Exploring the critical factors in pharmaceutical supply chains revealed during COVID-19 and addressing missing links

The COVID-19 pandemic revealed profound weaknesses in global pharmaceutical supply chains, resulting in widespread shortages of critical medical supplies, delayed drug manufacturing, and disruptions in vaccine distribution. These supply chain vulnerabilities were exacerbated by several key factors, including an overreliance on a limited number of countries for active pharmaceutical ingredients (APIs), insufficient local manufacturing capacity, and logistical constraints in transportation and distribution networks. The pandemic also exposed inefficiencies in regulatory frameworks, leading to delays in approvals and limited agility in responding to rapidly changing demands. Furthermore, the lack of transparency and real-time monitoring across global supply chains hindered effective decision-making and coordination, aggravating the crisis. This paper provides an in-depth analysis of the critical factors that contributed to pharmaceutical supply chain disruptions during COVID-19, identifying missing links such as the need for diversification of supply sources, enhanced flexibility in manufacturing processes, and the integration of advanced technologies like artificial intelligence (AI), blockchain, and automation for supply chain optimization. The analysis highlights how supply chain visibility, digital innovation, and risk management strategies could improve resilience in the face of future global health crises. In addition to identifying these challenges, the paper proposes solutions to address the missing links in pharmaceutical supply chains, including the decentralization of production, the development of regional manufacturing hubs, and the creation of public-private partnerships to bolster local production. The role of government policies in facilitating faster regulatory approvals, fostering international cooperation, and incentivizing innovation is also explored. Case studies on successful post-COVID-19 adaptations, such as the rapid scale-up of vaccine production and the reconfiguration of personal protective equipment (PPE) supply chains, offer insights into effective strategies for building more resilient systems. Ultimately, this paper underscores the importance of a collaborative, multi-stakeholder approach to ensuring the stability and security of pharmaceutical supply chains. It calls for proactive measures to strengthen global supply chain infrastructures, improve regulatory agility, and embrace emerging technologies that can predict and respond to disruptions. These steps are crucial to safeguarding the continuous delivery of essential pharmaceuticals during future pandemics or other large-scale disruptions, ensuring global health security in an increasingly interconnected world.

Environmental and economic assessment of mixed plastic waste pelletization in the Gulf Cooperation Council region

Pelletizing mixed plastic wastes (MPW) has gained interest as an upcycling technology and an alternative to conventional recycling. To investigate its potential, we conducted a cost analysis and life-cycle assessment (LCA) for a conceptual pelletization facility designed to produce 1 kg of pellets per batch of MPW (comprising polyethylene—PE and polypropylene—PP). This work has the following merits: (i) evaluating environmental impact (EI), cost analysis, and mechanical strength based on actual experimental data and its comparison with local and international manufacturers; (ii) enabling the evaluation of LCA impacts of MPW pellets; and (iii) emphasizing the significance of waste management in reducing EIs. The following ten EIs were assessed: climate change (CC), net energy, particulate matter formation, natural land transformation, metal depletion, marine ecotoxicity, ionising radiation, freshwater ecotoxicity, freshwater eutrophication, and terrestrial ecotoxicity. The CC of the as-synthesized pellets is 1.26 kg CO2 eq., significantly lower than the data obtained from the Gulf Petrochemicals and Chemicals Association (GPCA) and an actual plant in Gulf Cooperation Council (GCC) countries. Additionally, the net energy required for the production of 1 kg of pellets is 54.1 MJ, while the cost is around 0.55 USD. The tensile strength of MPW pellets (24.63 MPa) falls between that of PE virgin pellets (21.12 MPa) and PP virgin pellets (28.12 MPa). This suggests that the MPW pellets exhibit competitive strength characteristics, warranting its consideration for applications where moderate strength is required. Overall, the competitive cost, coupled with the reduced EIs, demonstrates the potential of pelletization as a sustainable and economically viable waste management solution.

Effects of importing second-hand clothes on supply chains: insights for Africa’s textiles and apparel industry

ABSTRACT Some African countries import a large number of second-hand clothes. This paper examines how importing second-hand clothes affects Africa’s textile and apparel (TA) supply chain. We find that the availability of second-hand clothes could benefit consumers because it provides a new option to consumers. However, import bans and the importation of second-hand clothes may help or hurt local TA manufacturers and workers’ incomes depending on the cost structures for new and second-hand clothes. Imposing import tariffs restrains the second-hand clothing business, helps local TA manufacturers and improves consumer welfare if the quality of new clothing is competitive. Our findings provide insights into how governments use distribution management to protect local TA manufacturers in Africa. Encouraging agents to sell in the local market is desirable if a government wants to help local manufacturing firms and workers. However, if a government wants to collect more tariffs, not allowing second-hand clothing importers to sell through retailers is wise.

Enhancing Rwanda's Global Competitiveness: Evaluating the Impact of 'Made in Rwanda' Policies on Local Manufacturing Growth and Innovation

The study aimed at Enhancing Rwanda's Global Competitiveness: Evaluating the Impact of 'Made in Rwanda' Policies on Local Manufacturing Growth and Innovation. The specific objectives of the study were: to establish the impact of ‘Made in Rwanda’ policies on the growth of local manufacturers in Kenya sectors between 2017 and 2023; and to examine the extent to which ‘Made in Rwanda’ policies have improved the competitive advantage of local manufacturers in regional and international markets. Descriptive research, a method of gathering data, was used in this study to address inquiries about the present state of the research participants. The sample size of 246 respondents was proportionally distributed across the different sectors. The main instrument that was used for data collected was a semi-structured questionnaire. Descriptive statistics was used to show trends and inferential statistics was used to anlyse the relation between the various variables with multiple regression analysis crowing the hypothesis testing. Crucially insightful results came from the regression study done to investigate the link between the 'Made in Rwanda' policies and local manufacturers' competitive advantage. Here, the regression equation could be shown as Y=2.5+0.7X1+0.5X2+ε. With an intercept (β0) at 2.5, local manufacturers' competitive advantage is expected to be 2.5 units should both independent variables equal zero. With β1=0.7, the coefficient for Growth 'Made in Rwanda' Policies shows a direct link whereby competitive advantage rises by 0.7 units for every unit increase in growth policies. With p < 0.001, this is statistically significant and indicates rather strong evidence on the favorable impact of growth policy on company competitive advantage. With β2=0.5, the coefficient Competitive Advantage "Made in Rwanda" Policies also shows that, alongside every unit increase in competitive advantage policies, each caused a 0.5 unit increase in competitive advantage of manufacturers. This is statistically significant (p = 0.01) and once more shows to be especially crucial for raising competitiveness. For local producers, the correlated independent variables explain 68 percent of the variance in competitive advantage. All things considered, 'Made in Rwanda' policies have greatly helped the local manufacturer to grow over the past few years. According to the study's findings, strategic actions including policy incentivizing, infrastructure access, and capacity-building initiatives have improved production capability and market positioning. Thanks to these policies, local producers will not only develop but also be more suited to compete against foreign players on their path into regional and worldwide markets. This rightly emphasizes the need of a constant and adequate government support as well as an ongoing assessment of these policies to guarantee they remain relevant and efficient in handling the problems encountered in the manufacturing sector Keywords: 'Made in Rwanda' policies, local manufacturers, competitive advantage, production output, employment growth, export volume, product differentiation, policy incentives, infrastructure, government support programs, trade agreements, and capacity building.

A Study of Pradhan Mantri Surya Ghar Yojna and Its Impact on Household Electricity Costs and Decreasing Dependency on Conventional Energy Sources

According to research, the Pradhan Mantri Surya Ghar Yojna has a significant impact on sustainable energy practices by lowering household electricity costs through rooftop solar installations and reducing India's dependency on foreign energy sources. The Yojna lessens the environmental effect of traditional energy usage by enabling homes to switch to greener options by promoting access to renewable energy. The program's subsidies and incentives increase access to solar energy, promoting its widespread adoption by both urban and rural families. In addition to lowering household power costs, its widespread adoption helps India meet its challenging targets for lowering carbon emissions and fostering environmental sustainability. Through the creation of chances for local manufacturers, skilled workers, and industries to engage in the solar energy value chain, the project also promotes socioeconomic development. The initiative supports India's larger sustainable energy aims by offering a framework for rooftop solar panel installations, guaranteeing long-term financial gains and promoting energy independence. There are difficulties, mostly associated with the initial high cost of installing solar panels and the difficulties in obtaining funding or subsidies, but they are gradually being resolved by means of incentives and policy changes from the government. Overall, by making solar energy more accessible, cheap, and appealing to Indian homes, the Pradhan Mantri Surya Ghar Yojna has played a significant role in defining sustainable energy habits and supporting the nation's wider economic and climatic goals.

Research progress and application of pectin: A review.

Pectin, an acidic polysaccharide, is naturally present primarily in the cell walls and inner layers of higher plants. Pectin is extensively used in food, pharmaceutical, cosmetic, and other industries owing to its exceptional attributes encompassing superior gelation, emulsification, antioxidant activity, stability, biocompatibility, and nontoxicity. Due to the increasing demand for pectin, there is a short supply in the domestic pectin market. Currently, the domestic production of pectin is heavily reliant on imports, thus emphasizing the urgent need to enhance its local manufacturing capabilities. Due to the diverse sources of pectin and variations in extraction and purification methods, its content, physicochemical properties, and biological activity are influenced, consequently impacting the market application of pectin. Therefore, this paper comprehensively reviews the extraction and purification process of pectin, in vivo metabolism, and biological activities (including antitumor, immunomodulatory, anti-inflammatory, antioxidant, hypoglycemic and hypolipidemic effects, antimicrobial properties, accelerated wound healing potential, promotion of gastrointestinal peristalsis, and alleviation of constipation as well as cholesterol-lowering effect). Furthermore, it explores the diverse applications of pectin in food science, biomedicine, and other interdisciplinary fields. This review serves as a valuable resource for enhancing the efficiency of pectin content improvement and exploring the potential value and application of pectin in a more scholarly and scientifically rigorous manner.

A Comprehensive Assessment of Quality of Antimalarial Medicines in Mainland Tanzania: Insights from Five Years of Postmarket Surveillance.

Sustainable access to high-quality antimalarial medicines is pivotal to achieving universal and effective malaria control. Poor-quality antimalarial medicines are prevalent in sub-Saharan Africa, impeding malaria control initiatives and claiming the lives of many children. Regular monitoring of the quality of antimalarial medicines is crucial to ensure the quality of service to the community. A cross-sectional study using a postmarket surveillance (PMS) approach was conducted from 2019 to 2023. Samples were collected from the port of entry, local manufacturers, and various distribution outlets in 15 regions of mainland Tanzania. The samples were subjected to tier 1 evaluation, comprising a product information review (PIR) and identification using the Global Pharma Health Fund-Minilab® techniques. Samples that failed the identification tests and 10% of the samples from distribution outlets that passed the tests were subjected to confirmatory testing (tier 2), which included assays, related substances, dissolution, and sterility per the pharmacopeial monographs. During five annual PMSs, 2,032 antimalarial samples were collected and subjected to quality tests. All samples complied with the standard specifications for identity, dissolution, related substances, sterility, physical evaluation, disintegration, and assay. A total of 292 (55.5%) tested samples failed the PIR evaluation, with incomplete package information in leaflets contributing to 64.7% of all deviations. Antimalarial medicines circulating in the mainland Tanzanian market meet expected quality standards. Continuous monitoring of the quality of antimalarial medicines is recommended.

The African Medicines Agency and Medicines Regulation: Progress, challenges, and recommendations.

In response to the situation of the African healthcare system, the African Medicines Agency (AMA) was established by the African Union (AU) to regulate access to medicines and support the local manufacture of medications. This study aimed to describe the factors that enabled the establishment of the African Medicines Agency and its successes, challenges, and perceived benefits. We reviewed data sources that explored the progress and challenges of the African Medicines Agency and Medicines Regulation in Africa. The SPIDER framework was used to organise the research focus and to extract the keywords for the literature search. The study data were obtained from PubMed Central, ScienceDirect, and Google Scholar. Out of 249 studies screened, 19 were selected for this narrative review. Critical successes observed in the agency's establishment include the appointment of a Special Envoy, the selection of its headquarters, and the signing of its treaty by 37 member states. However, it is hindered by poor political commitment, differences in risk-benefits interpretation and organizational structure, weak legal and regulatory frameworks, inadequate financial mechanisms, and inadequate political and policy leadership in some member states. The value of AMA in achieving optimal health outcomes and its other benefits must be considered despite the challenges being encountered. Therefore, all member states should adopt the best procedures in signing and ratifying the treaty and implementing associated commitments to improve efficiency and accountability in African medicine regulation.

Assessing Business Viability for a Production Joint Venture in the Indonesian Medical Device Industry

Research Aims: This study examines the viability of a joint venture between Daenamic Health Inc., a South Korean medical device manufacturer, and PT. Kenari Jaya Perkasa, an Indonesian medical device importer, to establish a local production facility for high-end medical devices in Indonesia. Design/methodology/approach: The research follows a structured approach involving the analysis of business model compatibility, external market dynamics, and the financial and operational viability of the joint venture. Employing qualitative analysis from discussions, VRIO Framework, and quantitative analysis from Analytic Hierarchy Process (AHP), the study evaluates market conditions and strategic fit between the partners. Research Findings: Findings indicate that Daenamic Health Inc. and PT. Kenari possess complementary strengths, forming a synergistic partnership poised to become a leading local brand for high end medical technology, as well as enabling access to more export market. Motivated by the need to reduce Indonesia's dependency on import, especially highlighted during the COVID-19 pandemic, this venture aligns with government policies to enhance local manufacturing and healthcare infrastructure. However, challenges such as navigating regulatory landscapes, managing a layered cost structure, and training local human capital must be addressed. Theoretical Contribution/Originality: Preliminary assessment for the joint venture’s establishment helps the partners to comprehensively assess their internal situation both as individual business and as future partners, prior to capitalizing the opportunity that comes with Indonesia’s vision towards healthcare self-sufficiency. As a result, partners’ synergistic strengths and aligned individual business needs positions the venture for competitive pricing and expansion in Southeast Asia and beyond. Keywords: Medical Devices; Joint Venture; Local Manufacturing; Market Dynamics; Strategic Fit

Business Ecosystem Architecture Development: A Case Study of IoT Business in the Transportation Industry

The research aims to study business ecosystem architecture in the Internet of Things (IoT) scope, especially in the transport industry. This research uses a qualitative approach with the Research and Development (R&D) method with the Modeling Business Ecosystem Architecture (TEAM) research design. Informants consist of internal and external sources who provide a practical and comprehensive perspective on the IoT transportation business ecosystem at Telkom Indonesia. Data collection was conducted through in-depth interviews, observations, and literature studies. The results showed that, in mapping the IoT business ecosystem in Telkom Indonesia’s transportation sector. The findings highlighted several challenges, such as the limited readiness of human resources and the lack of local device manufacturers resulting in a lack of competitiveness of IoT solutions. There is a need for a business ecosystem architecture that focuses on examining actors, roles, and value offered and mapping interactions between actors. With a cocreation approach, actors in the ecosystem can actively collaborate in designing, developing, and implementing more innovative and adaptive solutions. Through the cocreation process, customers, service providers, application developers, and other actors can share knowledge, experiences, and resources to create solutions that better suit the needs and expectations of all parties involved. This research maps the IoT business ecosystem in the transport sector developed by Telkom Indonesia. Telkom Indonesia is a solution provider, where the importance of collaboration of each actor, including device providers, application developers, and customers, is crucial to overcoming challenges and maximizing the ecosystem’s potential.

Enhancing the supercapacitive performance of soot material induced with manganese cobaltite (MnCo2O4) for supercapacitor application

Processing waste carbonaceous materials into useful products presents a sustainable alternative to its recovery. An effective and environmentally benign way of reusing such waste is to convert them into electrodes capable of supporting energy conversion reactions. This study introduces a cost-effective synthesis of a composite electrode for supercapacitor application using a waste carbonaceous soot obtained from Tema Steels Limited, a local steel manufacturing company in Ghana, having it subjected through thermal treatment at 500 °C and synergizing with annealed MnCo2O4 to augment the soot’s supercapacitive capabilities. The fabricated composite electrode comprises treated (thermally activated) soot combined with annealed MnCo2O4 material in 1:1 mass ratio, using a facile hydrothermal synthesis technique. Halogen like chlorine negatively affect the supercapacitive performance of soot, the as-received soot was subjected to a 500°C, 2-hour thermal treatment to optimize its performance, effectively reducing chlorine content from 4.1 to 2.1 at. weight percent and notably augmenting its specific surface area (SSA). SSA increased from 183.3 m2g−1 to 253.3 m2g−1, a 27.6 % increment after thermal treatment. The electrode’s supercapacitive performance was utilized using a 3 M KOH electrolyte solution employed in a three-electrode system. Attaining a current density of 3Ag−1, the composite electrode achieved a specific capacitance of 2818 Fg−1. The fabricated composite electrode demonstrated a stable charge/discharge capability by retaining around 87 % of its capacity after 10,000 cycles, establishing its practicality for applications in electrochemical storage.

Civil society activism for Africa's vaccine and local manufacturing agenda: Can mpox be the test case?

Civil society activism for Africa's vaccine and local manufacturing agenda: Can mpox be the test case?

Technology foresight in Indonesia: developing scenarios to determine electrical vehicle research priority for future innovation

Purpose The purpose of this study is to determine research areas that are most favorable in supporting the development and manufacturing of electric vehicle (EV) components locally in Indonesia for 2025–2035. Therefore, will provide direction for the formulation of the related government policies and programs. Consequently, an EV technology research priority must be identified. Design/methodology/approach A technology foresight (TF) procedure which consists of a STEEPV analysis, followed by scenarios development and expert elicitation techniques, was conducted to determine an EV technology research priority that may direct future specific local component innovations, and therefore businesses. Findings The results of this study indicate that research in a range of EV battery technologies, technologies relating to a variety of key components (to increase local content) and autonomous systems were important to support the local development and manufacturing of EV components in Indonesia. Research limitations/implications In this study, the scenarios development process was conducted based on selected available experts, mostly internally from BRIN. Some biased opinions may be present. Originality/value There have not been any TF studies regarding the development of EV technology research priority in Indonesia.

DETERMINATION OF SOME PHARMACOKINETIC PROPERTIES OF ARTEMETHER-LUMEFANTRINE GRANULES IN ALBINO RATS

Aim and Objectives: Malaria is an infectious disease that is caused by plasmodium parasites which is rampant in Sahara Africa and children under 5 years of age are highly vulnerable to this infection by malaria. So the need for the formulation of dosage form for this population using naturally occurring excipients to replace imported ones being currently used by our local manufacturing industries in-order to formulate novel, readily available, affordable and effective antimalarial medicine for children. Methods: Using the local excipients and its hybrid, the formulated artemether-lumefantrine granules for oral suspension were administered to albino rats, blood samples were collected at predetermined time 0, 1.5, 3, 6, 9, 12, 15, 18, 21, and 24 h respectively and drug contents; artemether-lumefantrine were determined within the stipulated period. Results: Some pharmacokinetic parameters determined were; maximum concentration, Cmax, time to reach the maximum concentration, Tmax, half-life, t1/2, area under the curve, AUC, and mean residence time, MRT, which were for artemether-lumefantrine were 3.9, 3.4, μg/L; 3.2, 6.0 h; 12.5, 14 h; 75.8, 168.5 μg/L.h; 24, 24 h respectively, for the marketed artemether-lumefanthrine granules for oral suspension.4.1, 3.2 μg/L; 1.4, 3.0 h; 3.0, undefined h, 67.0, 65.7 μg/L. h; 18, 18 respectively for hybrid formulated artemether-lumefantrine granules for oral suspension and 3.1, 3.8 μg/L; 2.5, 12.5 h; 4.8, 15 h; 20.2, 281.6 μg/L .h; 18, 18 respectively for the extracted pectin formulated granules. Conclusion: Optimized formulated artemether-lumefantrine granules were superior to the marketed product in terms of pharmacokinetic values being closer to those of earlier workers. Peer Review History: Received 13 May 2024; Reviewed 16 July 2024; Accepted 22 August; Available online 15 September 2024 Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com Average Peer review marks at initial stage: 5.5/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id Dr. Sangeetha Arullappan, Universiti Tunku Abdul Rahman, Malaysia, sangeetha@utar.edu.my

COMPARATIVE CURE AND SUPPRESSION EFFICACY OF FORMULATED GRANULES WITH A MARKETED SIMILAR PRODUCT

Aim and Objectives: Malaria, a major global health challenge which makes antimalarial drugs one of the commonly prescribed class of drugs World-wide. The most vulnerable are the children and the women especially the expectant mothers. There is need to develop locally and readily available excipients from natural sources to replace imported ones currently being used by our local manufacturing industries. The purpose of the investigation was to test the formulated granules for oral suspension. Methods: Some weighed albino rats were infected with Plasmodium berghei, then the standard dose of the artemether-lumefantrine oral suspension formulated, a marketed product, and distilled water were administered ; 4/24 mg artemether-lumefantrine per kg body weight per oral to weighed albino rats. Then, other groups were administered standard dose of different formulated granules, a marketed similar product and distilled water respectively. These treated albino rats were then infected with Plasmodium berghei and blood samples were withdrawn from the tail veins, stained with Giemsa stain and the Plasmodium berghei count for the untreated and treated albino rats were determined. Results: The percentage clearance and suppression were calculated for the different formulations; pectin and its hybrid formulations, a marketed product and distilled water as a control which were 83.73, 85.2, 74.9 and 2.62, and 83.74, 85.2, 74.22, and 0% for curative and suppressive efficacies respectively. Conclusions: The investigations revealed that the most effective was the hybrid-formulated granules were closely followed by pectin-formulated granules and the least was the marketed product. Peer Review History: Received 17 May 2024; Reviewed 12 July 2024; Accepted 20 August; Available online 15 September 2024 Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com Average Peer review marks at initial stage: 6.0/10 Average Peer review marks at publication stage: 7.0/10 Reviewers: Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id Dr. Ahmad Abdelsattar El-Ebiary, Tanta University Hospitals, Tanta, Egypt, a.ebiary@med.tanta.edu.eg

Gillette’s Expansion to India through the Lens of Porter’s Diamond Model and Dunning’s Eclectic Paradigm

In 2005, Procter & Gamble (P&G) acquired Gillette for $57 billion, marking a significant milestone in consumer goods history. This analysis explores Gillette's strategic expansion into India, leveraging Porter's Diamond Model and Dunning's Eclectic Paradigm to evaluate its success and challenges. The study delves into the skilled workforce, local manufacturing, and innovative marketing strategies that facilitated Gillette's penetration into India's diverse and rapidly urbanizing market. Through local R&D and collaborations with e- commerce platforms, Gillette tailored its products to Indian consumer preferences, achieving substantial market share. The frameworks reveal how Gillette's global efficiency and local responsiveness enabled it to thrive amidst intense competition. The paper concludes with recommendations for sustaining this success through continuous innovation, vigilant market monitoring, and eco-friendly practices, while suggesting the applicability of these insights to other emerging markets.

Study of integration processes in the pharmaceutical market in the context of the development of territorial pharmaceutical ecosystems

Introduction. The ecosystem approach to the organization of business processes in the pharmaceutical market meets the prevailing trends, so the growth index of e-commerce in the retail sector of medicines for 5 years amounted to 1.87. The market distribution sector of medicines in the Russian Federation is characterized by a shift in corporate governance towards marketing cooperation based on aggregation electronic trading platforms (AETPS). Development of territorial pharmaceutical ecosystems (TFE) As a new integrative tool for managing the pharmaceutical development – production – distribution cycle, in order to achieve the target model of PHARMA 2030 at the territorial level, it requires the development of regulatory mechanisms for managing the supply of medicines. Objective: characteristics of integration processes in the industrial, wholesale and retail sectors of the pharmaceutical market to assess the potential competitiveness of territorial pharmaceutical ecosystems. Material and methods. The primary data for the analysis were: volumes of wholesale commodity residues of medicines produced in the Ural Federal District (461 registration certificates; proprietary Price and Distribution Test data for 230 trade names of LP EMIS data 2021–2022; Alpharm data 2021–2022; Datainsight 2022. In the course of the study, a structural analysis of the pharmaceutical market, a functional analysis of participants in the pharmaceutical product chain, and a marketing analysis were carried out. Results. It was found that the dynamics of the AETP segment development corresponds to the outstripping growth of highly integrated platforms: the short-term growth index of 5-pl AETP (Uteca) is 164%, 4-pl (Eapteca) is 55%, 3pl-AETP (averaged) is 36.5%. The absence of formal mechanisms of regional protectionism for the sale of finished dosage forms of local manufacturers in the Ural Federal District has been revealed. We have obtained the results of evaluating the effect of ecosystem integration of certain types of pharmaceutical market participants. For manufacturers of medicinal products, it was determined that the median coefficient of penetration of the local assortment of medicinal products into the pharmaceutical market in the context of ATX groups of level 2 is 0.67, which indicates a significant diversification of the assortment portfolio and the possibility of its aggregation without a barrier of internal competition. In the wholesale drugs sector, the potential for saving margins on medicines has been identified when implementing the scenario of localization of supplies in production regions in low and medium-low price ranges (30 – 550 rubles/unit), varying between 53–67%. It was found that the median share of regional distribution in the Ural Federal District (in packages) is 20.72%. It has been established that the Ural Federal District is one of the leaders in terms of the share of omnichannel consumers in the pharmaceutical market (63%), which is a significant incentive for the integration of organizations in the retail sector of the pharmaceutical market into the ecosystem 5pl platform. Conclusion. Situational analysis of the morphology of cooperative interactions in the pharmaceutical market allowed us to identify the prerequisites for the formation of ecosystem-organized management structures in the pharmaceutical market system – territorial pharmaceutical ecosystems. We have systematized incentives for ecosystem determination of medicines supplies, and found that: an additional channel for the market distribution of the industrial range of medicicnes in the Urals is not associated with a barrier to internal competition of pharmaceutical plants; the inclusion of regional suppliers in TFE will allow to form additional competitiveness in the “buyer's market” in conditions of market dominance of federal suppliers; the omnichannel approach to the distribution of the retail range of TFE in pharmacy organizations has a high projected conversion rate. A detailed assessment of integration processes in certain sectors of the pharmaceutical market did not reveal critical barriers to the introduction of TFE.

Barriers Towards Renewable Energy Development In Housing Areas In Serdang, Malaysia

Nowadays, new and renewable sources of energy are among the most crucial factors in achieving sustainable development of nations. The aim of this research is to investigate the current barriers to renewable energy development in Serdang, which are: financial, technical, and policy barriers. This study survey is located in Serdang area. Total sample of 346 respondents participated in this study. The finding of this study revealed a significant positive relationship with the financial barriers (r=0.501, p<0.05), technical and technological barriers (r=0.349, p<0.05), policy barriers (r=0.338, p<0.05), andrenewable energy development. Also a significant impact from the financial barriers, technical barriers, policy barriers, and renewable energy development. As high cost ofrenewable energy technologies forms one of the financial barriers, it is recommended that the import taxes be reduced and local manufacturing of these technologies be encouraged.