The Caswell Sub-basin, situated within the Browse Basin in the North West Shelf constitutes one of Australia’s primary hydrocarbon producing regions, with notable gas-condensate producing fields including Ichthys and Prelude. Jurassic syn-rift sandstones are extensively distributed across the basin and serve as one of the major reservoirs. However, reservoir sequences are typically intensely faulted and exhibit heterogeneity in thickness and lithofacies, with some areas experiencing localised erosion on uplifted fault blocks (e.g. Northern Caswell Sub-basin). Hence, understanding the nature of the 3D fault patterns and their growth history is crucial for evaluating the reservoir characteristics for field development and additional exploration activities. This study, therefore, aims to evaluate the structural framework and the tectonic evolution of the Caswell Sub-basin. Detailed structural interpretation of Paleozoic and younger sequences was conducted using multiple 3D seismic datasets extending over Ichthys, Prelude, Lasseter, and Crown fields. Our study focuses mainly on Mesozoic faulting patterns and kinematics evaluated from interpreted structural maps, thickness changes of each stratigraphic interval and fault throw profiles of major bounding faults. The extensional phase during the Early–Middle Jurassic triggered the development of NE–SW trending faults and the deepening of the Brewster Graben. While, from the Late Jurassic to the Early Cretaceous, the development of E–W trending faults in the north of the Crown and Lasseter fields indicate a shift in the regional stress regime. We highlight the importance of evaluating the structural linkage from basement to cover sequences to achieve a comprehensive understanding of reservoirs and associated petroleum systems.