Local Amplification Research Articles

Influence of distributed hydrogen injection and combustion on supersonic boundary layer stability and transition

This theoretical study recorded the influence of the distributed injection of hydrogen through a permeable surface and its combustion on the stability and transition of a supersonic boundary layer (BL). The laminar base flow for a multicomponent flat-plate BL was computed using the computational fluid dynamics solver with finite-rate chemistry for free-stream Mach number (M) = 2. Linear stability theory (LST) equations for a reactive gas mixture were derived in the local parallel base flow approximation. Stability calculations based on the developed theory revealed the possibility of a decrease in the local spatial amplification rates of unstable perturbations. A double reversal in the maximal amplification rate magnitudes of perturbations was obtained, wherein at first, they increased, then decreased to zero, and then rose again. The influence of the distributed injection and combustion of hydrogen in the supersonic BL on the position of the laminar-turbulent transition was estimated using the LST-based eN-method. Calculated and experimentally obtained dependencies of the relative transition Reynolds number on the relative mass flow rate of injected hydrogen were compared. It was found that depending upon the flow conditions, the hydrogen diffusion flame could accelerate or decelerate the transition in the supersonic M = 2 BL, when compared to absence of hydrogen burning. Two counteracting effects compete: heat supply by combustion exerts stabilizing influence, while low-molecular-weight gas blowing from the surface exerts destabilizing influence. Depending on the interplay of these two factors, it would be possible to obtain acceleration or deceleration of transition.

Bladder microenvironment actuated proteomotors with ammonia amplification for enhanced cancer treatment.

Enzyme-driven micro/nanomotors consuming in situ chemical fuels have attracted lots of attention for biomedical applications. However, motor systems composed by organism-derived organics that maximize the therapeutic efficacy of enzymatic products remain challenging. Herein, swimming proteomotors based on biocompatible urease and human serum albumin are constructed for enhanced antitumor therapy via active motion and ammonia amplification. By decomposing urea into carbon dioxide and ammonia, the designed proteomotors are endowed with self-propulsive capability, which leads to improved internalization and enhanced penetration invitro. As a glutamine synthetase inhibitor, the loaded l-methionine sulfoximine further prevents the conversion of toxic ammonia into non-toxic glutamine in both tumor and stromal cells, resulting in local ammonia amplification. After intravesical instillation, the proteomotors achieve longer bladder retention and thus significantly inhibit the growth of orthotopic bladder tumor invivo without adverse effects. We envision that the as-developed swimming proteomotors with amplification of the product toxicity may be a potential platform for active cancer treatment.

Coarse-grained model simulation-guided localized DNA signal amplification probe for miRNA detection

DNA-based enzyme-free signal amplification strategies are widely employed to detect biomarkers in low abundance. To enhance signal amplification, localized DNA reaction units which increases molecular collision probability is commonly utilized. However, the current understanding of the structure-function relationships in localized DNA signal amplification probes is limited, leading to unsatisfied performance. In this study, we introduced a coarse-grained molecular model to simulate the dynamic behavior of two DNA reaction units within a DNA enzyme-free signal amplification circuit called Localized Catalytic Hairpin Assembly (LCHA). We investigated the impact of localized distance and flexibility on reaction performance. The most efficient LCHA probe guided by simulation exhibits sensitivity 28 times greater that of free CHA, with a detection limit of miR-21 reaching 16 pM, while the least effective LCHA probe demonstrated a modest improvement of only 7 times. We successfully employed the optimized probe to differentiate cancer cells from normal cells based on their miR-21 expression levels, showcasing its quantification ability. By elucidating the mechanistic insights and structure-function relationship in our work, we aim to contribute valuable information that can save users' time and reduce costs when designing localized DNA probes. With a comprehensive understanding of how the localization affects probe performance, researchers can now make more informed and efficient decisions during the design process. This work would find broad applications of DNA nanotechnology in biosensing, biocomputing, and bionic robots.

Vs30 and depth to bedrock estimates from integrating HVSR measurements and geology-slope approach in the Oslo area, Norway

In order to estimate well-constrained seismic hazard and risk on local scales, the knowledge of site amplification factors is one of several important requirements. Seismic hazard studies on national or regional scales generally provide the level of earthquake shaking only at bedrock conditions, thereby avoiding the difficulties that are caused through local site effects. Oftentimes, local site conditions are not well understood or even non-existent. In this study we investigate an efficient and non-invasive methodology to derive the local average shear wave velocity in the uppermost 30 m of the ground (Vs30). The Vs30 value is a useful parameter to define soil classes and soil amplification used in seismic hazard assessment and to extend the knowledge of the site to include the depth to basement rock. At the level of the municipality of Oslo, there is currently no map available that describes the Vs30, and as such any seismic risk study is lacking potentially critical information on local site amplification. The new proposed methodology includes the use of existing well databases (with knowledge on minimum basement depth), topographic slope derived from Digital Elevation Models (as a proxy for both depth to basement and Vs30, integrated with geological maps) and near-surface Quaternary geological maps. The Horizontal to Vertical Spectral Ratio (HVSR) method and a statistics-based geological mapping tool (COHIBA) are used to integrate the various sources of data estimates. Finally, we demonstrate our new methodology and workflow with data from three different regions within the Oslo municipality and propose an approach to conduct cost-efficient mapping for seismic site amplification on a general municipality scale.

Amplification factor transport transition model for high-speed flows

A fully local amplification factor transport model is developed for high-speed transitional flows. On the basis of the approximate eN envelope method of linear stability theory, two transport equations are established to describe the evolution of amplification factors for first- and second-mode instabilities in high-speed boundary layers. An intermittency factor transport equation is then constructed based on the transported amplification factors and is coupled with Menter’s k−ω shear-stress transport eddy-viscosity turbulence model. The new model is validated through several test cases under different flow conditions, including flat plates, straight and flared cones, and a double ramp configuration. Comparisons with linear stability theory and experimental data demonstrate the ability of the model to predict the transition behavior induced by first- or second-mode instabilities. The model provides a reasonable reflection of the effects of different parameters that influence transitions, including the Mach number, temperature, nose bluntness, and pressure gradient.

What Was the Level of Ground Motion across Europe during the Great A.D. 365 Crete Earthquake?

Abstract Historical and archeological data report that an earthquake was felt over the whole eastern Mediterranean on 21 July A.D. 365. The impact of the tsunami it generated, which may have caused several thousands of fatalities, has been widely studied, whereas the impact of the seismic waves has hardly been explored. Here, we present simulations of the ground motion caused by the A.D. 365 event at 316 sites now instrumented by seismological stations throughout Europe. The simulation approach is based on the modeling of a series of rupture scenarios coupled with empirical Green’s functions (EGFs) obtained at the stations from a recent Mw 6.4 earthquake. The broadband and remarkably also the accelerometric records in urbanized areas can be exploited at distances as far as ∼2000 km. Then, we use three empirical models to estimate the macroseismic intensity across Europe from the simulated peak ground accelerations and peak ground velocities. The presence of stations in thick sedimentary basins (lower Danube valley, Po plain, urban accelerometric network in the alpine valley of Grenoble) shows that local basin amplification effects can dominate acceleration values at frequencies favorable to human earthquake perception (~0.5–1 Hz), even for basins located at more than 1500 km from the earthquake. Thus, our simulations indicate that the A.D. 365 earthquake was likely felt by the populations as far as the Po plain and as the city of Grenoble, about 1800 km away, and presumably in other large European basins such as the Pannonian basin. It is possible that the perception of the earthquake up to such distances contributed to its “universal” character perpetuated in archival sources. At closer distances (300–500 km), the simulated intensity levels indicate that the earthquake probably caused no damage.

TGF-β1 mediates tumor immunosuppression aggravating at the late stage post-high-light-dose photodynamic therapy.

Photodynamic therapy (PDT) is an emerging clinical treatment that is expected to become an important adjuvant strategy for the immunotherapeutic cancer treatment. Recently, numerous works have reported combination strategies. However, clinical data showed that the anti-tumor immune response of PDT was not lasting though existing. The immune activation effect will eventually turn to immunosuppressive effect and get aggravated at the late stage post-PDT. So far, the mechanism is still unclear, which limits the design of specific correction strategies and further development of PDT. Several lines of evidence suggest a role for TGF-β1 in the immunosuppression associated with PDT. Herein, this study systematically illustrated the dynamic changes of immune states post-PDT within the tumor microenvironment. The results clearly demonstrated that high-light-dose PDT, as a therapeutic dose, induced early immune activation followed by late immunosuppression, which was mediated by the activated TGF-β1 upregulation. Then, the mechanism of PDT-induced TGF-β1 accumulation and immunosuppression was elucidated, including the ROS/TGF-β1/MMP-9 positive feedback loop and CD44-mediated local amplification, which was further confirmed by spatial transcriptomics, as well as by the extensive immune inhibitory effect of local high concentration of TGF-β1. Finally, a TGF-β blockade treatment strategy was presented as a promising combinational strategy to reverse high-light-dose PDT-associated immunosuppression. The results of this study provide new insights for the biology mechanism and smart improvement approaches to enhance tumor photodynamic immunotherapy.

Surface-enhanced fluorescence for lipopolysaccharide analysis based on shell-isolated nanoparticle

Lipopolysaccharide (LPS) as the component of cell membrane on gram-negative bacteria played a central role on inflammatory inducer to stimulate a multi-system host response. Herein, a surface-enhanced fluorescent (SEF) sensor was developed for LPS analysis based on shell-isolated nanoparticles (SHINs). The fluorescent signal of CdTe quantum dots (QDs) was amplified by silica shell-coated Au nanoparticles (Au NPs). The 3D finite-difference time-domain (3D-FDTD) simulation revealed that this enhancement was due to local electric field amplification. This method has a linear detection range of 0.1–20 μg/mL and a detection limit of 64 ng/mL for LPS. Furthermore, the developed method was successfully applied for LPS analysis in milk and human serum sample. The results indicated that the as-prepared sensor has significant potential for selective detection of LPS in biomedical diagnosis and food safety.

Stochastic Approach for 2D Superficial Seismic Amplification Based on Quad4M; City of L’Aquila (Italy) Test Case

The values of the physical–mechanical properties of any soil are affected by uncertainties both due to experimental measurements and the impossibility of knowing them, in detail, at every point of the spatial domain. Accordingly, this work focuses on uncertainty in shear wave velocity (Vs) and its impact on the seismic response. The Monte Carlo method, based on pseudo-random number generation, was selected. To understand which random distributions could identify the site’s real conditions, the Fourier spectrum frequencies were calculated for each realization and were compared with the predominant natural site frequency. The experimental range data were used to calculate the spectral average acceleration and the horizontal amplification factors. The simulations were performed and interpreted by a modified version of VisualQ4M software based on 2D Quad4M, including the generation of pseudo-random numbers and pre- and post-data processing. A site at a small scale, in the territory of the city of L’Aquila (Italy), was selected as the test case. This paper demonstrates, from a numerical point of view, that both a simple local topographic modification due to excavation and the uncertainties of the numerical values, even of the shear wave velocity alone, can have an important impact on the local seismic amplification.

Simulation of the 2022 Mw 6.6 Luding, China, earthquake by a stochastic finite-fault model with a nonstationary phase

We adopted stochastic finite-fault simulations considering the nonstationary frequency characteristics for the 2022 Mw 6.6 Luding, China, earthquake at 16 strong-motion stations using the stochastic finite-fault model based on a dynamic corner frequency (EXSIM) code. The average simulated response spectra of earthquake ground motions were obtained and then compared with response spectra of 5% damped single degree of freedom system under recorded ground motion excitation to verify whether the finite-fault model that considers the nonstationary frequency characteristics can reproduce the critical characteristics of ground motions and improve the simulation accuracy. The high-frequency spectral decay is calculated by the real recordings and the stress drop is determined by the trial-and-error method. In addition, the local site amplifications are estimated from the horizontal-vertical spectral ratio (H/V). An improved EXSIM that considers the slip-related corner frequency is also used in this study. The results indicate that the nonstationary phase can significantly improve the simulation accuracy of EXSIM in the short period and has little effect on the long-period simulation results. However, the effect of the nonstationary phase on the simulation results obtained from the improved EXSIM is not significant. Regarding the peak ground acceleration (PGA), the nonstationary phase can produce waveform characteristics that are more similar to the real waveform, and the synthetic PGA is closer to the observed ones.

Directional Amplification at Rock Sites in Fault Damage Zones

Site effects refer to the modification of ground shaking caused by the local geological conditions that can result in the strong amplification of ground motion. The best-known cause for site effects is the presence of superficial soft soil deposits, which are considered in seismic design codes of many countries through the use of scaling factors. Rock sites are assumed to show no local site amplification. However, even at rock sites, seismic waves can be locally amplified at frequencies of engineering interest, with larger motion along one site-specific azimuth on the horizontal plane (the so called “directional site resonance or amplification”). These effects have been related to the presence of large-scale open cracks or microcracks in different geological environments (faults, landslides, volcanic areas) everywhere with a common signature: maximum amplification occurs transverse to the predominant fracture strike. In this paper, we summarize our main results obtained in the last decade with regard to several fault zones with different kinematics, where ground motion is polarized (and amplified) perpendicularly to the predominant fracture field as an effect of the stiffness anisotropy. In order to give a further constraint, we also show some cases where the directional amplification effects were compared with the S-wave splitting analysis method.

Magnetically tunable ultralow threshold optical bistability by exciting LRSPR in InAs/graphene layers at the terahertz region.

With the experimental corroboration employing a transfer matrix method, an analytical observation of optical bistability using long-range surface plasmon resonance (LRSPR) through the external magnetic field is presented for a very low threshold value. The proposed analytical method has been verified with the reported experimental data provided by Liu etal. [Curr. Appl. Phys.29, 66 (2021)1567-173910.1016/j.cap.2021.06.003]. Now theoretical analysis is further extended in the proposed multilayered structure comprising an InAs layer sandwiched between two graphene layers, whose electromagnetic response at 2THz can be regulated by employing a magnetic field and may tune the optical bistability without modifying the geometry or the characteristics of the structure. The observed threshold intensity for the switch-up is 6.6615×104 W/c m 2 at 0.001T; thus, this analytical approach is able to achieve 2 orders lower threshold for magnetically tunable upswitching of the optical bistable process. This suggested magnetically adjustable optical bistable arrangement gives a possibility for the comprehension of optical logic gates, optic memory, opto-transistors, and switches at a low switching threshold due to extraordinary features of the composite layers due to local field amplification of the graphene layer.

Climatological Features of the Vento Norte Phenomenon in the Extreme South of Brazil

Downslope windstorm known as Vento Norte (VNOR; Portuguese for “North Wind”) is a common phenomenon that occurs in southern Brazil during the winter season. Hence, this study attempted to investigate the climatological characteristics of VNOR using seventeen years (2004–2020) of hourly observations collected at seven meteorological stations distributed over the central region of Rio Grande do Sul State. The VNOR windstorm episodes are identified by intense wind gusts and warm air advection from the northern direction. They were selected from the data set obtained during the winter in the city of Santa Maria (SM). Statistical analysis showed that the detected VNOR events were characterized by mean wind gusts ≈15 m.s-1, mean wind direction of 350° and mean air temperature of 27 °C. Average duration of the events was about 9 h, with the longest event lasting 21 h. Characteristics and effects of this phenomenon were compared with those in other locations (meridional and zonal sections). Average values of wind gusts from the northern direction presented a significant increase of ≈200% for the winter period in SM. Nonetheless, a less significant increase in wind gusts was recorded in the meridional (28%) and zonal (41%) sections away from SM. The central location of SM has favorable topographic characteristics for this amplification, with a sharp altitude difference caused by the plateau- plain interface of ≈300 m. Our findings showed that the VNOR phenomenon mainly affects the climate of the southern region of Brazil, with a local amplification in the city of SM.

Improving NonViral Gene Delivery Using MHz Bursts of Nanosecond Pulses and Gold Nanoparticles for Electric Field Amplification.

Gene delivery by the pulsed electric field is a promising alternative technology for nonviral transfection; however, the application of short pulses (i.e., nanosecond) is extremely limited. In this work, we aimed to show the capability to improve gene delivery using MHz frequency bursts of nanosecond pulses and characterize the potential use of gold nanoparticles (AuNPs: 9, 13, 14, and 22 nm) in this context. We have used bursts of MHz pulses 3/5/7 kV/cm × 300 ns × 100 and compared the efficacy of the parametric protocols to conventional microsecond protocols (100 µs × 8, 1 Hz) separately and in combination with nanoparticles. Furthermore, the effects of pulses and AuNPs on the generation of reactive oxygen species (ROS) were analyzed. It was shown that gene delivery using microsecond protocols could be significantly improved with AuNPs; however, the efficacy is strongly dependent on the surface charge of AuNPs and their size. The capability of local field amplification using AuNPs was also confirmed by finite element method simulation. Finally, it was shown that AuNPs are not effective with nanosecond protocols. However, MHz protocols are still competitive in the context of gene delivery, resulting in low ROS generation, preserved viability, and easier procedure to trigger comparable efficacy.

Seismic metamaterials based on coupling mechanism of inertial amplification and local resonance

Inertial amplification mechanisms could be used to control the propagation of elastic waves in beams and slabs, but it was a difficult problem to apply inertial amplification mechanisms to seismic metamaterials to design low-frequency broadband. This paper presents a inertially amplified locally resonant seismic metamaterial (IALR-SM) using the coupling mechanism of inertial amplification and local resonance. In contrast to the locally resonant seismic metamaterial (LRSM), the large-mass columns as local resonators of IALR-SM are attached to the connector and small-mass columns to form the inertia amplification structures. The finite element method calculates the eigenmodes’ band structure and displacement vector field. Numerical results indicated that the bandwidth of the IALR-SM increases by 194% compared to LRSM for seismic surface waves below 20 Hz. The formation mechanism of the yield in large band gaps is attributed to the coupling mechanism of local resonance and inertial amplification. In addition, the numerical effects of geometric parameters on the band gaps are investigated. The findings showed that the side length of the small-mass columns plays a vital role in determining which coupling mechanism is dominant. Finally, field experiments demonstrated that the IALR-SM generates low-frequency broadband.

Erratum: Combining earthquake ground motion and ambient vibration recordings to evaluate a local high-resolution amplification model—Insight from the Lucerne area, Switzerland

An erratum on: Janusz P, Perron V, Knellwolf C and Fäh D (2022) Combining Earthquake Ground Motion and Ambient Vibration Recordings to Evaluate a Local High-Resolution Amplification Model—Insight From the Lucerne Area, Switzerland. Front. Earth Sci. 10:885724. doi: 10.3389/feart.2022.885724An omission to the funding section of the original article was made in error. The following sentence has been added: "Open access funding was provided by ETH Zurich".The original version of this article has been updated.

Insights into the conditions of application of noise-based spectral ratios in a highly industrialized area: a case study in the French Rhone Valley

SUMMARY The local ground motion amplification related to the geology at a specific site (i.e. the so-called site effects) may be classically quantified through the SSR (standard spectral ratio) technique applied on earthquake recordings. However, such a quantification might be challenging to carry out in low-to-moderate seismicity regions. Methods based on background ambient noise, such as noise-based standard spectral ratio (SSRn), might be of great interest in these areas. But noise-derived amplification is particularly sensitive to local anthropogenic sources, which may introduce biases in the evaluation of site effects by dominating the geological effects, especially for frequencies higher than 1 Hz. A hybrid approach (SSRh), developed to reduce biases in noise-based spectral ratios by combining classical earthquake-based spectral ratio (SSR) and SSRn, was recently introduced and relies on a site reference. We here investigate the applicability of SSRn and SSRh in a heavily industrialized environment in the Tricastin Valley (south-east France), where critical facilities are located. We continuously recorded ambient noise from 2020 February to March on a 400-sensor seismic array covering an area of about 10 km by 10 km. We demonstrate that SSRn and SSRh computed below 1 Hz are able to reproduce amplification factors provided by SSR. By contrast, at frequencies higher than 1 Hz, SSRn strongly deviates from SSR. SSRh shows closer results to SSR but presents a dependence to the choice of the local site reference, thereby questioning the possibility to use SSRh blindly to estimate the local amplification in our context. These discrepancies reflect the impact of local anthropogenic sources. We therefore introduced a two-step workflow to mitigate the influence of local sources. The first step is to define a characteristic time window to optimally isolate significant transient signals. The second step consists in selecting the time segments that do not contain these transients with a clustering-based approach. By applying this workflow, we were able to remove some strong anthropogenic transient signals likely to be generated by local sources at some sites and therefore to locally improve the amplification assessment through noise-based spectral ratios. However, stationary sources, whose impact cannot be removed through our procedure, remain a major issue. This study provides some insights into the application of SSRn and SSRh in noisy industrialized areas, especially regarding the impact of local noise sources. It illustrates the difficulty of having a procedure for mitigating the impact of these sources that is efficient everywhere inside such a complex anthropized environment, where different types of sources (including stationary sources) cohabit.

Frequency-dependent site amplification functions for key geological units in Iceland from a Bayesian hierarchical model for earthquake strong-motions

A fundamental modeling assumption in engineering seismology is that seismic ground motion is affected by source, propagation path and site effects. Contrary to the first two, comprehensive studies on site effects, the localized amplification effects on seismic ground motion due to the uppermost geological structure, have been limited in Iceland. As a result, site amplification has been modeled in ground motion models in a simplistic and qualitative way. In this study, we address this limitation by using the new Bayesian hybrid GMM proposed by Kowsari et al. (2020) to model the recorded ground motions at regional strong-motion stations in southwest Iceland, specifically the peak ground acceleration and pseudo-acceleration response spectra as a function of oscillator period (i.e., PGA and PSA at T=0.01-3.0 s), earthquake magnitude, distance and hypocentral depth, and at first, we omit a site-term. Then, we incorporate the GMM in a Bayesian Hierarchical Model (BHM) that allows prior distributions of model parameters to be used and we partition the model residuals into various terms associated with the source, propagation path and station terms. Through Bayesian inference of the model parameters the results show that the station term residuals reveal a frequency-dependent site amplification at the recording sites. By inspecting this systematic behaviour, we propose four groups of station terms by their characteristics. We then carefully inspect the station locations in terms of their associated geological unit and observe that the geological units and station term groups are qualitatively correlated. By combining the two, we propose the first frequency-dependent average site amplification functions associated with key geological units in Iceland based on age and formation. Provisionally we refer to them as hard rock, rock, (Holocene) lava rock, and (unspecified) soil site classes, respectively. We then update the GMM by incorporating these amplification functions so that it now enables the prediction of PGA and PSA at these four site classes. As a result, the new model standard deviations are considerably lower, with those associated with the event term being τ = 0.05, station terms φS2S = 0.10, intra-event φ = 0.17 and total σ = 0.18 in common logarithm units for PGA. The new site class-specific GMM now enables the site-specific ground motion for separate geological units which in turn improves site-specific seismic hazard assessment and informed site-specific engineering decision making in Iceland.

Scenario-based earthquake damage assessment of highway bridge networks

In earthquake-prone regions, the evaluation of seismic impacts on bridges is crucial to mitigation, emergency, and recovery planning for highway networks. The degree of bridge damage determines the cost and time required for repairs and the level of post-earthquake functionality including disruption of transportation network, increased costs due to reduction of traffic flow and restricted access to emergency routes. The article presents the methodological development and implementation of an interactive web application for rapid geospatial assessment and visualisation of earthquake damage scenarios of municipal highway bridge networks based on open access datasets. The proposed framework consists of the following successive models: hazard, inventory, damage, and impact. The seismic hazard model generates spatial distribution of the shaking intensity for earthquake scenarios in terms of ground motion intensity measure using ground motion prediction equations based on seismic hazard model for Eastern Canada. The shaking intensities are then modified with local site amplification factors based on the Canadian highway bridge design code values. The inventory model provides a database of existing bridges based on open-access data which are then classified according to their seismic vulnerability. The damage model assesses seismic performance of classes of bridges by applying respective fragility functions represented as probabilistic relationships between the intensity measure and the degree of expected damage. The impact model evaluates the post-earthquake traffic-carrying capacity of the highway network based on the predicted damage including repair cost as a percentage of replacement cost of bridges and inspection priority. The web-application is demonstrated with a bridge network in Quebec City including 117 bridges subjected to 180 earthquake scenarios. The proposed methodology is particularly useful to facilitate direct communication of potential impacts to emergency managers and city transport officials.

Pressure and temperature dependence of the electric modulus and loss factor of Poly(vinyl alcohol)/Poly(vinylidene fluoride) blends reinforced with Nano - Graphene platelets

Poly(vinyl alcohol)/Poly(vinylidene fluoride) blends reinforced with Nano - Graphene Platelets render piezoelectric by combining uniaxial plastic deformation end polarization. Comparative Broadband Dielectric Spectroscopy on fresh and piezoelectric specimens were carried oud at various temperature and hydrostatic pressure states. Dc conductivity, which results from inter-NGP fluctuation induced tunneling of electrons through the effective potential barrier set by the polymer, involves two charge transfer mechanisms. The shift of the glass transition temperature and the temperature triggering a kinetic process due to the enhancement of the mobility of water molecules bound to PVA, upon pressure are detected indirectly through associated changes to the conductivity modes. NGP filling induces a couple of interfacial charge trapping. Relaxations exhibit different thermodynamics and different dependencies for fresh and piezoelectric specimens on pressure. Hydrostatic compression of heterogeneous matter results in an inhomogeneous internal stress field, whereas stress is locally amplified. In PNC, small scale relaxation is disturbed by the spatial fluctuation of the internal stress field. Rendering the PVdF grains piezoelectric, local stress amplification induces fluctuations of the local electric field. Fluctuations (of the internal stress or electric field) affect rather a short-range charge relaxation, rather than macroscopic dc conductivity.