Loading Rate Research Articles

Habitual Nocturnal Sleep, Napping Behavior, and Recovery Following Training and Competition in Elite Water Polo: Sex-Related Effects.

To examine nocturnal sleep patterns, napping behaviors, and subjective wellness responses of elite water polo players within an in-season week and to identify whether sleeping patterns differ between men and women. Sleep characteristics of 10 male and 17 female professional water polo players were objectively assessed during 1week of the in-season period, including 5 training days, 1 match day, and 1day of rest. Internal load (rating of perceived exertion × duration of training or match) was assessed 30 minutes posttraining or postmatch, and the total quality of recovery was recorded every morning. A series of multilevel models were used to analyze the data. Time in bed and wake-up time were earlier on both training (P < .001) and rest days (P < .001) than on the day of the match. Internal workload did not predict any of the players' sleeping patterns. Midday naps predicted less time in bed (P = .03) and likely less sleep time (P = .08). The total quality of recovery was predicted only by the total sleep time (P < .01). Women exhibited higher sleep efficiency (P < .001), less waking after sleep onset (P = .01), and a lower number of awakenings (P = .02) than men. The current results indicate that the nocturnal sleep patterns of elite water polo players are not associated with internal load and that women display better nocturnal sleep quality compared with men. As long naps interfere with nocturnal sleep, and total nocturnal sleep time predicts total quality of recovery, we suggest that athletes follow hygiene sleep strategies to facilitate adequate nocturnal sleep and next-day recovery.

Viscoelastic Model of Fiber Concrete under Dynamic Loading Considering the Effect of Initial Stresses

Statement of the problem. The objective of the study was to identify the peculiarities of the stress-strain state of fiber concrete under two-stage static-dynamic loading and to develop a variant of a nonlinear viscoelastic model of concrete reinforced with steel fiber. Results. The paper presents the results of experimental tests of fiber-concrete prisms under quasi-static, dynamic and static-dynamic loading conditions. On the basis of the analysis of experimental data it is established that at dynamic loading there is an upward shift of the boundary of macrocrack formation. A nonlinear viscoelastic model of fiber concrete is proposed and compared with experimental data, taking into account the effect of the initial stress level caused by the service load. The parametric study performed using this model shows that as the loading rate increases, a more intensive dynamic hardening of concrete is observed. Conclusions. The proposed viscoelastic model of fiber concrete allows to estimate the ultimate strength and corresponding strain under static-dynamic mode of loading due to an accidental action caused by the collapse of one of the load-bearing members of the structural system of the building.

Smart and Sustainable Crop Protection: Design and Evaluation of a Novel α-Amylase-Responsive Nanopesticide for Effective Pest Control.

In this study, an α-amylase-responsive controlled-release formulation was developed by capping polydopamine onto β-cyclodextrin-modified abamectin-loaded hollow mesoporous silica nanoparticles. The prepared Aba@HMS@CD@PDA were subjected to characterization using various analytical techniques. The findings revealed that Aba@HMS@CD@PDA, featuring a loading rate of 18.8 wt %, displayed noteworthy release behavior of abamectin in the presence of α-amylase. In comparison to abamectin EC, Aba@HMS@CD@PDA displayed a significantly foliar affinity and improved rainfastness on lotus leaves. The results of field trail demonstrated a significantly higher control efficacy against Spodoptera litura Fabricius compared to abamectin EC at all concentrations after 7, 14, and 21 days of spaying, showcasing the remarkable persistence of Aba@HMS@CD@PDA. These results underscore the potential of Aba@HMS@CD@PDA as a novel and persistently effective strategy for sustainable on-demand crop protection. The application of nanopesticides can enhance the effectiveness and efficiency of pesticide utilization, contributing to more sustainable agricultural practices.

Feeding frequency efficacy on biogas yield of oily substrate anaerobic digestion in continuous stir tank reactor

ABSTRACT Anaerobic treatment of oily substrate, known as grease trap waste (GTW), was investigated for its practicability via continuous stirred tank reactor (CSTR) at different operating conditions and selected recovery strategies of feeding frequency efficacy. This study determine the performance of feeding frequency efficacy, namely feeding every 24 hours (R24H) and feeding every 12 hours (R12H). Under organic loading rate (OLR) of 2.2 gCOD/L.day, R12H exhibited methane composition of 57%, methane production rate of 0.27 LCH4/L.day, and methane yield of 0.14 LCH4/gCODremoved. At the same OLR, R24H recorded methane composition of 60%, methane production rate of 0.29 LCH4/L.day and similar methane yield as R12H. Findings indicated that R24H showed performance comparable to that of R12H. Given minor variation observed in performance, it is recommended that plant operators may consider scheduling 2 times feeding per day for low loading conditions and switch to 1 time feeding per day for higher loading conditions. This strategy is designed to balance the system and prevent shock loads, which could lead to plant shutdowns. This mechanism will induce their conversion to volatile fatty acids (VFAs); thus, reducing the risk of acid accumulation and pH drops, which could inhibit methanogens to produce methane, especially for oily substrate.

Ecofriendly Controlled-Release Insecticide Carrier: pH-/Temperature-Responsive Rosin-Derived Hydrogels for Avermectin Delivery against Mythimna separata (Walker).

The exploration of environmentally friendly, less toxic, sustained-release insecticide is increasing with the growing demand for food to meet the requirements of the expanding population. As a sustained-release carrier, the unique, environmentally friendly intelligent responsive hydrogel system is an important factor in improving the efficiency of insecticide utilization and accurate release. In this study, we developed a facile approach for incorporating the natural compound rosin (dehydroabietic acid, DA) and zinc ions (Zn2+) into a poly(N-isopropylacrylamide) (PNIPAM) hydrogel network to construct a controlled-release hydrogel carrier (DA-PNIPAM-Zn2+). Then, the model insecticide avermectin (AVM) was encapsulated in the carrier at a drug loading rate of 36.32% to form AVM@DA-PNIPAM-Zn2+. Surprisingly, the smart controlled carrier exhibited environmental responsiveness, strongly enhanced mechanical properties, self-healing ability, hydrophobicity, and photostability to ensure a balance between environmental friendliness and the precision of the drug release. The release experiments showed that the carboxyl and amide groups in the polymer chains alter the intermolecular forces within the hydrogel meshes and ingredient diffusion by changing temperatures (25 and 40 °C) and pH values (5.8, 7.4, and 8.5), leading to different release behaviors. The insecticidal activity of the AVM@DA-PNIPAM-Zn2+ against oriental armyworms was good, with an effective minimum toxicity toward aquatic animals. Therefore, AVM@DA-PNIPAM-Zn2+ is an effective drug delivery system against oriental armyworms. We anticipate that this ecofriendly, sustainable, smart-response carrier may broaden the utilization rosin and its possible applications in the agricultural sector.

Correlation between cytomegalovirus (CMV) viral load and mortality rate in individuals with acquired immunodeficiency syndrome (AIDS)

AIDS (acquired immunodeficiency syndrome) stems from immune deficiency caused by HIV (human immunodeficiency virus). CMV (cytomegalovirus), opportunistic in HIV/AIDS patients, is associate with mortality at elevated viral loads in individuals with AIDS. Objective: accomplish an integrative review to analyze the relation between CMV viral load and mortality rate in patients with AIDS. Methods: Usage of full review was made by following the said steps: theme identification and research questions structuring; definition of inclusion criteria; selection of articles based on scientific data; evaluation and analysis of selected studies; result interpretation and display of the final full review; insert method description. Result: High CMV viral loads are associated with elevated mortality in individuals with AIDS. Conclusion: It confirms the presence of a correlation between an increase in CMV viral load and an increase in the mortality rate of immunosuppressed patients, associates with viral loads ≥ 1000 copies/ml, marking this as a risk cutoff.

Effect of nozzle diameter and raster orientation on tensile and fracture behavior of FDM‐PLA specimens under mixed‐mode I/II loading

AbstractFused deposition modeling (FDM) is a material extrusion technique that works by extruding molten filament on a heated platform. In this method, several manufacturing parameters are engaged which affect the mechanical performance of printed parts. In this study, the effects of nozzle diameter on tensile (under two loading rates) and mixed‐mode I/II fracture behavior of printed specimens were examined. The obtained results revealed that testing speed had a minor effect on basic mechanical properties. For instance, ultimate tensile strengths of tensile specimens printed with 1 mm nozzle diameter were 32.56 and 39.71 MPa for test speeds of 1 and 5 mm/min, respectively. Higher nozzle diameters resulted in higher mechanical properties and fracture resistance (e.g., specimens printed with 45/−45° raster angle with 0.4 and 1 mm nozzle diameters indicated fracture loads of 4520 and 5071 N, respectively). Besides, fracture loads were predicted through the equivalent material concept coupled with J‐integral method.

Correlations between moisture expansion and flexural properties of bamboo strips in response to different loading rates

AbstractBamboo and bamboo products, known for their hygroscopic nature, exhibit sensitivity to different loading rates in dry conditions. However, with the increasing prevalence of heavy and extended precipitation events due to global warming, there is still a lack of investigation on the response of bamboo strips to various loading rates after being attacked by moisture. In this study, the bending properties of bamboo strips after exposure to extremely high-humidity environments were investigated to assess their responses to varying loading rates. Throughout different exposure durations, bamboo strips exhibited varying moisture contents up to 112% and evident volumetric moisture expansion. After moisture exposure, bamboo strips exhibited heightened sensitivity in flexural strength and modulus to loading rates, with the most pronounced sensitivity observed at 33.9% moisture content. In addition, a linear relationship was established between flexural strength loss and volumetric expansion rather than moisture content. Notably, the samples exhibited greater sensitivity in strength loss to moisture expansion under lower loading rates. These findings preliminarily elucidate how loading rates impact the mechanical properties of bamboo strips across varying moisture levels, contributing to understanding the deterioration in the properties of engineered bamboo products when exposed to high humidity and rainy environments with potential collision events.

Thermosensitive and mucoadhesive gels containing solid lipid nanoparticles loaded with fluconazole and niosomes loaded with clindamycin for the treatment of periodontal diseases: a laboratory experiment

BackgroundPeriodontal diseases may benefit more from topical treatments with nanoparticles rather than systemic treatments due to advantages such as higher stability and controlled release profile. This study investigated the preparation and characterization of thermosensitive gel formulations containing clindamycin-loaded niosomes and solid lipid nanoparticles (SLNs) loaded with fluconazole (FLZ), as well as their in vitro antibacterial and antifungal effects in the treatment of common microorganisms that cause periodontal diseases.MethodsThis study loaded niosomes and SLNs with clindamycin and FLZ, respectively, and assessed their loading efficiency, particle size, and zeta potential. The particles were characterized using a variety of methods such as differential scanning calorimetry (DSC), dynamic light scattering (DLS), and Transmission Electron Microscopy (TEM). Thermosensitive gels were formulated by combining these particles and their viscosity, gelation temperature, in-vitro release profile, as well as antibacterial and antifungal effects were evaluated.ResultsBoth types of these nanoparticles were found to be spherical (TEM) with a mean particle size of 243.03 nm in niosomes and 171.97 nm in SLNs (DLS), and respective zeta potentials of -23.3 and -15. The loading rate was 98% in niosomes and 51% in SLNs. The release profiles of niosomal formulations were slower than those of the SLNs. Both formulations allowed the release of the drug by first-order kinetic. Additionally, the gel formulation presented a slower release of both drugs compared to niosomes and SLNs suspensions.ConclusionThermosensitive gels containing clindamycin-loaded niosomes and/or FLZ-SLNs were found to effectively fight the periodontitis-causing bacteria and fungi.

Effects and molecular mechanisms of jet ablation and fuel corrosion on separation failure of the asphalt-aggregate interface in airport asphalt pavements

To guide the improvement of asphalt pavement durability in airports, the effects and molecular mechanisms of jet ablation and fuel corrosion on separation failure of the asphalt-aggregate interface were investigated in this study using molecular dynamics simulations and density functional theory method. Firstly, tensile separation behaviors of the virgin, aged, and fuel-corroded asphalt-aggregate interfaces were simulated under different loading rates to evaluate their tensile strength and fatigue cracking resistance, and the experimental data were also used to verify the reliability of the simulation results. Subsequently, the molecular mechanisms of jet ablation and fuel corrosion on the separation failure of the asphalt-aggregate interface were analyzed by calculating the work of adhesion, work of cohesion, flowability parameters, and intermolecular binding energy. The results show that the aged specimen has higher ultimate tensile strength and fracture energy, but its flexibility and fatigue cracking resistance are significantly reduced. This is because the polar oxygen-containing groups generated during high-temperature aging enhance the intermolecular binding energy of the asphalt, but this also restricts the diffusion of asphalt molecules, resulting in greater frictional resistance and viscosity of asphalt during shear deformation, and thus loss of mobility and self-healing properties. On the contrary, since the light and medium oils soften and dilute the asphalt, and also weaken the intermolecular binding energy of asphalt, the fuel corrosion reduces the ultimate tensile strength and fracture energy of the asphalt-aggregate interface system, resulting in insufficient overall strength and load-bearing capacity.

Microfluidic Electroporation Arrays for Investigating Electroporation-Induced Cellular Rupture Dynamics

Electroporation is pivotal in bioelectrochemistry for cellular manipulation, with prominent applications in drug delivery and cell membrane studies. A comprehensive understanding of pore generation requires an in-depth analysis of the critical pore size and the corresponding energy barrier at the onset of cell rupture. However, many studies have been limited to basic models such as artificial membranes or theoretical simulations. Challenging this paradigm, our study pioneers using a microfluidic electroporation chip array. This tool subjects live breast cancer cell species to a diverse spectrum of alternating current electric field conditions, driving electroporation-induced cell rupture. We conclusively determined the rupture voltages across varying applied voltage loading rates, enabling an unprecedented characterization of electric cell rupture dynamics encompassing critical pore radius and energy barrier. Further bolstering our investigation, we probed cells subjected to cholesterol depletion via methyl-β-cyclodextrin and revealed a strong correlation with electroporation. This work not only elucidates the dynamics of electric rupture in live cell membranes but also sets a robust foundation for future explorations into the mechanisms and energetics of live cell electroporation.

Experimental Study on the Performance of Glass/Basalt Fiber Reinforced Concrete Unidirectional Plate under Impact Load

Fiber-reinforced composite materials have emerged as essential solutions for addressing the durability challenges of traditional reinforced concrete, owing to their lightweight nature, high strength, ease of construction, superior tensile capacity, robust corrosion resistance, and excellent electromagnetic insulation properties. This paper delves into the influence of loading rate and fiber bar type on the mechanical characteristics of concrete one-way plates through impact experiments on such plates fitted with glass/basalt fiber bars at varying drop weight heights. The test results reveal a direct correlation between increasing loading rates and escalating damage in fiber-reinforced concrete one-way plates, reflected in the progressive rise in peak deflection and residual displacement at the mid-span of the specimens. Notably, when subjected to higher impact loads, glass fiber-reinforced concrete specimens exhibit amplified deformation and intricate crack formations, consequently diminishing the overall deformation resistance of the plate. Furthermore, glass/basalt fiber-reinforced composites demonstrate notable vibration damping qualities, characterized by substantial residual displacement, minimal rebound, and rapid decay following vibration stimulation. Overall, glass fiber-reinforced one-way plates display marginally superior impact resistance compared to their basalt fiber-reinforced counterparts.

The power of Para sport: the effect of performance-focused swimming training on motor function in adolescents with cerebral palsy and high support needs (GMFCS IV) – a single-case experimental design with 30-month follow-up

ObjectiveThis study aims to evaluate the effect of a performance-focused swimming programme on motor function in previously untrained adolescents with cerebral palsy and high support needs (CPHSN) and to determine...

Investigating the failure mechanism of X-shaped non-persistent joints under uniaxial loading: Experimental and numerical analysis

In this paper, rock samples containing non-persistent cracks of ‘‘X’’- shape were prepared and experimentally studied under uniaxial compression. Then, the numerical simulations of these tests were established using dynamic finite element software (LS-DYNA). Various joint configurations are assumed and their lengths are considered to change from the center of “X” in different rock specimens. The cracks propagation patterns, the failure processes, and energy absorptions during the tests are studied. The gypsum samples’ dimensions were 10 × 10 × 5 cm and one “X” shaped non-persistent crack was provided inside each specimen. The tensile strength of gypsum samples was 1 MPa. The notch's lengths are similar in some three cases while the length of one wing of the crossest joint varied in two other cases. In two residual cases, the length of the two wings of the crossest joint was varied. The opening of the crack was 1 mm. Angel between the notch trajectories was 90°. The model was subjected to an applied axial load rate of 0.05 mm/min. Results show that the failure mechanism of specimens was affected by notch length. The larger notch has a dominant effect on the breakage mode and failure strength. Newborn tensile cracks originated at the notch tip and propagated parallel to the loading axis to merge with the model boundary. Both the crack initiation stress and breakage stress were decreased by increasing the notch length. The absorbed energy has a minimum value when two large notches with a length of 6 cm exist in the model while it has a maximum value when notch lengths are equal to 2 cm. The increase in notch length resulted in a decrease in the difference between strains associated with crack initiation stress and final stress, indicating progressive breakage. Whereas the difference between strains associated with crack initiation stress and final stress was increased by decreasing the notch length, therefore delay failure occurred after crack initiation in the model. The results obtained from both laboratory experiments and numerical simulations show good agreement in the failure progression.

Optimisation of the biological production of levulinic acid in a mixed microbial culture fed with synthetic grape pomace

Levulinic acid (LA) is a polymer with a vast industrial application range and can be co-produced as a minor by-product during the biological production of polyhydroxyalkanoates (PHA). However, the influence of key parameters as tools for favouring the production of LA over PHA is still unclear. In this study, we investigated how several critical operational conditions, i.e., carbon-nitrogen ratio (C/N), organic loading rate (OLR) and airflow, can be optimised to favour LA accumulation over PHA production by a mixed microbial culture (MMC), using synthetic grape pomace (GP) hydrolysate as the substrate. The results showed that it was possible to direct the MMC towards LA accumulation instead of PHA. The maximum LA yield was 2.7 ± 0.2 g LA/(L·d) using a C/N of 35, an airflow of 5 L/min and an OLR of 4 g sCOD/(L·d). The OLR and, to a lesser extent, the C/N ratio were the main factors significantly and positively correlated with the biological synthesis of LA.

Natural Fibre and Hybrid Composite Thin-Walled Structures for Automotive Crashworthiness: A Review

Natural fibres, valued for their low density, cost-effectiveness, high strength-to-weight ratio, and efficient energy absorption, are increasingly emerging as alternatives to synthetic materials in green composites. Although they cannot fully replace synthetic counterparts, like carbon, in structural applications due to their inferior mechanical performance, combining them through hybridization presents a potential solution. This approach promotes a balance between environmental benefits and mechanical efficiency. Recently, the transportation sector has shifted its focus towards delivering lightweight and crashworthy composite structures to improve vehicle performance, address safety concerns, and minimise environmental impact through the use of eco-friendly materials. The crashworthiness of energy absorbers, typically thin-walled structures, is influenced by several factors, including their material and geometric design. This paper presents a comprehensive overview of recent studies focused on the crashworthiness of fibre-reinforced, thin-walled composites under axial crushing. It explores different aspects, such as their materials, cross-sections, stacking sequences, triggering or filling mechanisms, and the effect of loading rate speed. Emphasis is placed on natural-fibre-based materials, including a comparative analysis of synthetic ones and their hybridization. The primary objective is to review the progress of solutions using green composites as energy absorbers in the automotive industry, considering their lightweight design, crashworthiness, and environmental sustainability.

Effective characterization for the dynamic indentation and plastic parameters acquisition of metals

As a fundamental test technique for the mechanical properties of materials, indentation shows broad application prospects. Compared to the well-studied quasi-static indentation, relatively few and incomplete studies on the dynamic indentation test and characterization have been performed. In this work, a dynamic indentation test technique based on the split Hopkinson pressure bar system is developed, and the corresponding “three-wave method” is proposed to effectively acquire the time-resolved dynamic indentation load and depth. Systematic indentation tests under different loading rates and indenter cone angles are conducted on typical metal materials such as Cu, α-Fe, and α-Ti. Based on the dynamic indentation contact stiffness analysis and indentation theory the indentation hardness under different loading conditions are determined. A procedure for plastic parameter inversion of metal materials, including strain hardening and strain rate strengthening terms based on dynamic indentation, is provided. The effectiveness is verified by the traditional compression test results, providing a new method for characterizing the dynamic mechanical properties of metal materials.

Spherical g-C3N4@PDA nanocarrier for synergistic chemo-photothermal tumor therapy

In this paper, by wrapping the near-infrared (NIR) response polydopamine (PDA) as a nanocoating on the surface of spherical nano graphitic phase carbon nitride (g-C3N4), a multifunctional g-C3N4/PDA (CNP) nanocarrier platform was prepared. The π-conjugation system in PDA and the electronegative hydroxyl groups on the surface of CNP promote the creation of abundant active sites, which had a high drug loading rate of about 98.5 % for the electropositive GA. Due to the strong NIR reaction of CNP, the release of GA from CNP/GA can be greatly accelerated by the rising temperature, bonding disruption and charge transfer. Moreover, the photo-generated electron-hole pairs could be excited by the NIR effect of CNP, which promotes the production of ROS (·OH, ·O2– and 1O2) to induce apoptosis in HepG2 cells. Thus, the present spherical CNP nanocarrier with a combination of enzyme-mimic activity and NIR-responsive properties has a great potential for chemo-photothermal synergistic tumor therapy.

Nanoindentation creep mechanism of gradient ultrafine lamellar γ+Ni5Zr eutectic using electromagnetic levitation coupled with fall casting

A quaternary Ni50Fe20Cr20Zr10 eutectic alloy was designed based on the Ni–Fe–Cr alloy, and the gradient ultrafine lamellar γ+Ni5Zr eutectic was achieved by means of electromagnetic levitation coupled with fall casting (EML-FC). The temperature field, the process of interface migration, microstructural characteristics and the nanoindentation creep property of the alloy were systematically analyzed. During the rapid solidification, since the conical surface served as the main heat dissipation channel, the solid-liquid interface moved from the conical surface towards the top of the cone axis. The gradual decrease in cooling rate from 105 to 103 K s−1 along this direction led to the formation of the gradient ultrafine lamellar γ + Ni5Zr eutectic with the size from 59 ± 12 to 140 ± 36 nm. The nanoindentation creep behavior and mechanism were analyzed by estimating the strain rate sensitivity and activation volume. As the interlamellar spacing of the eutectic decreased, the nanohardness and creep resistance of the alloy gradually increased owing to an increase in grain boundary density and the enhancement of coupling effect between dislocation and grain boundary. In addition, the creep behavior of alloy was sensitive to the loading rate. Increasing the loading rate led to an increase in strain rate sensitivity from 7.69 × 10−3 to 18.89 × 10−3 and a decrease in activation volume from 29 to 12 b3. This special eutectic structure and its improved nanohardness and creep resistance properties offered a potential opportunity to explore a new generation of alloys for the hot-end components of 972 K ultra-supercritical fossil-fired power plants.

Self-Diagnostic Opportunities for Battery Systems in Electric and Hybrid Vehicles

The number of battery systems is also growing significantly along with the rise in electric and hybrid car sales. Different vehicles use different types and numbers of batteries. Furthermore, the layout and operation of the control and protection electronics units may also differ. The research aims to develop an approach that can autonomously detect and localize the weakest cells. The method was validated by testing the battery systems of three different VW e-Golf electric vehicles. A wide-range discharge test was performed to examine the condition assessment and select the appropriate state of charge (SoC) for all three vehicles. On the one hand, the analysis investigated the cell voltage deviations from the average; the tests cover deviations of 0 mV, 12 mV, 60 mV, 120 mV, and 240 mV. On the other hand, the mean value calculation was used to filter out possible erroneous values. Another important aspect was examining the relationship between the state of charges (SoC) and the deviations. Therefore, the 10% step changes were tested to see which SoC level exhibited more significant voltage deviations. Based on the results, it was observed that there are differences between the cases, and the critical range is not necessarily at the lowest SoC level. Furthermore, the load rate (current) and time of its occurrence play an important role in the search for a faulty cell. An additional advantage of this approach is that the process currently being tested on the VW e-Golf can be relatively simply transferred to other types of vehicles. It can also be a very useful addition for autonomous vehicles, as it can self-test the cells in the system at low power consumption.