This study examines the design, development, and characterization of double friction pendulum systems with variable sliding surface geometry. The proposed isolator has a spherical surface with a small radius within an inner sliding range while different geometric functions are used to describe the sliding surface in the outer range. As a result of variable curvature used as sliding surface, the isolators exhibit an adaptive stiffness behavior with increasing displacement amplitude. First, the analytical equations that describe the characteristics of the proposed isolators were derived. Then, a large-scale prototype adaptive isolator that employs a logarithmic function for the sliding surface geometry in the outer range was fabricated. The response of the prototype isolator was characterized under increasing amplitude reversible cyclic loads considering two different levels of vertical isolator loads. A high-fidelity finite element model was developed to capture the response of the prototype isolator. The results obtained from the experimental tests and numerical simulations were used to verify the analytical equations derived for the proposed isolators. Next, a typical multi-span bridge structure was modeled with adaptive stiffness isolators and its response under bi-directional ground motions records were analyzed. In contrast to a conventional double friction pendulum bearing, the suggested isolators yield significantly reduced base shear forces while exhibiting greater isolator displacements. However, the proposed isolators retain the capability to effectively curtail excessive displacements, ensuring the prevention of collapse.