High-tech improvements with reference for health advance to develop numerous medical tools have been build to support doctors and nurses performances. This analysis research applied web-based system of infusion monitoring and microprosessor or microcontroller to grease performances of nursers and pharmaceutical helping in clinics or public health centers of the district. In this research, smart infusion web-based is builded for providing for the infusions by applying Node MCU and ESP 8266 Wi-Fi module. Smart Infusion aimed at helping nursers and medical helpers handling infusions of contagious complaint cases or Covid-19 cases to provide for infusion situation in isolation room or emergency room at hospital also public health centers at the district. Detecting the infusion weight, volume and percentage by applying a digital scale and the Load Cell sensors. This monitoring tools or devices is created to count the display from LCD and infusion weight the volumes and percentage of infusion with 3 colors alert display on the Website such as red color, yellow color, and green color depend on a web developed by php language, C programming with Arduino by C language embedded in microprocessor or microcontroller and based on fuzzy logic. Testing results have been achieved, monitoring device can work efficiently and completely when calculating weight, percentage, and volume. Scanning data of success accuracy of Load Cell sensors is 98,00%.