Live Technology Research Articles

Research on live detection technology in wireless charging of electric vehicles based on milli-meter wave radar

Recently, milli-meter wave radar has been recognized as efficient solution that has the capacity to contribute to live detection in wireless charging of electric vehicles. We discuss the importance of the live detection in wireless charging of electric vehicles and traditional solution like infrared sensor, ultrasonic detector and camera. This article proposes to apply milli-meter-wave radar to improve the reliability and accuracy of live detection. At the end of the article, the software and hardware design ideas of the scheme are proposed. It can effectively solve the safety and reliability problems in the existing electric vehicle wireless charging scenarios. At the same time, it can eliminate people's concerns about the safety of wireless charging technology and lay a good foundation for the promotion and further research of electric vehicle wireless charging technology.

(151) Development of a New Peyronie’s Disease Self-Assessment Screening App

Abstract Introduction Peyronie’s disease (PD) is a connective tissue disorder associated with the formation of fibrotic plaques in the tunica albuginea, leading to penile curvature. PD is underdiagnosed, and this may be related to the reluctance of some men to seek consultation with a health care provider (HCP). Objective The aim was to develop an English-language digital application (app) to increase PD awareness, give men concerned about penile curvature a self-screening tool, and provide a link for locating HCPs with expertise in PD. Methods The Peyronie’s Disease Self-Assessment App is Android- and iOS-compatible. It was developed as a self-assessment tool for screening purposes only. It is not intended to diagnose, treat, cure, or prevent any medical condition, disease, or health problem and should not be considered a replacement for a consultation with a physician. The app provides instructional videos on general features and how to perform a penile scanning procedure. Results The PD Self-Assessment App includes a questionnaire related to penile curvature, penetration difficulty, degree of bother for partner, and impact on sexual activity. An innovative feature of the app is a live scanning technology, which uses the phone’s camera to detect the contours of the penis from multiple angles and applies an algorithm that determines the degree of curvature. The resulting image is a 3D penile simulation in the app, which allows the user to mark the location of any “lumps.” The app will also produce a 2D outline to determine the maximum curvature. External links are provided to a PD education website and to locate an HCP. The patient can share both the questionnaire responses and penile curvature simulation with his HCP via the user’s native email. This tool has password protection features and encrypts sensitive data. The scan images are representations of the penis, not photographs. Images are stored in the app library and are not stored in the user’s photo gallery. To enhance security, all data are erased when the app is uninstalled. The app is adaptable and scalable as needed for future updates. Conclusions The PD Self-Assessment App will help improve patient knowledge of the condition, document penile deformity, and facilitate consultation with an HCP. For men with PD, the app will help ease their journey with PD. The app will assist HCPs with evaluation and diagnosis. Sequential documentation of penile curvature during medical treatment, during mechanical traction protocols, or following surgery will provide an evidence basis for tracking long-term outcomes in PD. Disclosure Yes, this is sponsored by industry/sponsor: Endo Pharmaceuticals Inc. Clarification Industry initiated, executed and funded study Any of the authors act as a consultant, employee or shareholder of an industry for: Endo Pharmaceuticals Inc.

Potential of omega-3 and conjugated fatty acids to control microglia inflammatory imbalance elicited by obesogenic nutrients

High-fat diet-induced obesity detrimentally affects brain function by inducing chronic low-grade inflammation. This neuroinflammation is, at least in part, likely to be mediated by microglia, which are the main immune cell population in the brain. Microglia express a wide range of lipid-sensitive receptors and their activity can be modulated by fatty acids that cross the blood-brain barrier. Here, by combining live cell imaging and FRET technology we assessed how different fatty acids modulate microglia activity. We demonstrate that the combined action of fructose and palmitic acid induce Ikβα degradation and nuclear translocation of the p65 subunit nuclear factor kB (NF-κB) in HCM3 human microglia. Such obesogenic nutrients also lead to reactive oxygen species production and LynSrc activation (critical regulators of microglia inflammation). Importantly, short-time exposure to omega-3 (EPA and DHA), CLA and CLNA are sufficient to abolish NF-κB pathway activation, suggesting a potential neuroprotective role. Omega-3 and CLA also show an antioxidant potential by inhibiting reactive oxygen species production, and the activation of LynSrc in microglia. Furthermore, using chemical agonists (TUG-891) and antagonists (AH7614) of GPR120/FFA4, we demonstrated that omega-3, CLA and CLNA inhibition of the NF-κB pathway is mediated by this receptor, while omega-3 and CLA antioxidant potential occurs through different signaling mechanisms.

How does online streaming reform e-commerce? An empirical assessment of immersive experience and social interaction in China

The present study examined why live-stream commerce is superior to traditional e-commerce since its retail sales have been booming in China and the communication style with live broadcast technology is entirely different. An integrated model was employed to predict the drivers or restraints of this new business model to substantiate the existence of a lacuna in understanding individual and situational influences. The research described a study that used a combination of information processing theory and flow theory within a Stimulus-Organism-Response (S-O-R) framework to investigate how individual factors and situational factors influence the experience of flow. An integrated model was proposed that stimuli such as individual (i.e., perceived interactivity) and situational influences (i.e., dynamic characteristics and atmosphere clues) can elicit the intrinsic states of organisms (i.e., immersive experience and social interaction), which then result in a response (i.e., online purchase intention). Some shoppers with live-streaming experiences in China were invited to participate in online surveys in 2020. The structural equation modeling results (n = 408) show that atmosphere clues and perceived interactivity of streaming attributes can contribute to both immersive experience and social interaction, predicting consumers’ intention to transact in the new e-commerce. However, the current dynamic/situational infrastructures can only improve the immersive experience but do not assure effective social interaction, leading to the need for continuous tasks in digital development and the directions for future research.

The Importance of Low-Cost Live Feed Culture Technology to the Marine Shrimp Industry during COVID-19

The Importance of Low-Cost Live Feed Culture Technology to the Marine Shrimp Industry during COVID-19

Wearable point-of-view live streaming technology in a virtual airway management workshop for medical students

Background: Trauma resuscitation skills are an essential part of medical training. Airway management skills are often learned via simulation-based training, but physical distancing restrictions have forced medical schools to transition their preclinical curricula to a virtual format. A wearable, point-of-view (POV), live streaming tool was piloted in a virtual airway management workshop to preclinical medical students to address limitations in the standard online curriculum. Methods: An anesthesiologist instructor donned a chest-mounted smartphone that captured POV video as it was connected to a Zoom video conference call. Simultaneously, a second camera view from a different angle was streamed from a laptop webcam. Preclinical medical student attendees watched the facilitator demonstrate airway management and resuscitation skills on a simulation mannequin. Student perceptions of the workshop were assessed via standardised course evaluations administered through the online student portal and a questionnaire distributed by the course representative. Results: Qualitative and quantitative course evaluation data showed that although this platform may not completely substitute in-person learning, students appreciated the alternative teaching style, particularly the use of POV video and multiple camera views. Generally, students believed that the learning objectives were achieved. Camera stability, camera positioning, and the distracting nature of the virtual student-instructor interactions were identified as areas for improvement. Conclusions: Moving forward, this innovative workshop format can act as a valuable framework for other institutions that wish to bridge gaps in current virtual education methods and enhance technical skills training in medical learners.

Parental experiences of live video streaming technology in neonatal care in England: a qualitative study

BackgroundThe use of bedside cameras in neonatal units facilitates livestreaming of infants to support parental and family bonding when they are unable to be physically present with their baby. This study aimed to explore the experiences of parents of infants previously admitted for neonatal care and who used live video streaming to view their baby in real-time.MethodsQualitative semi-structured interviews were conducted after discharge with parents of infants admitted for neonatal care on a tertiary level neonatal unit in the UK in 2021. Interviews were conducted virtually, transcribed verbatim and uploaded into NVivo V12 to facilitate analysis. Thematic analysis by two independent researchers was undertaken to identify themes representing the data.ResultsSeventeen participants took part in sixteen interviews. Thematic analysis identified 8 basic themes which were grouped into 3 organizational themes: (1) family integration of the baby including parent-infant, sibling-infant, and wider family-infant attachment facilitated through livestreaming, (2) implementation of the livestreaming service including communication, initial set up of the livestreaming service, and areas for improvement, and (3) parental control including emotional, and situational control.ConclusionsThe use of livestreaming technology can provide parents with opportunities to integrate their baby into their wider family and friendship community and gain a sense of control over their baby’s admission for neonatal care. On-going parental education around how to use, and what to expect from, livestreaming technology is required to minimise any potential distress from viewing their baby online.

Особенности проектирования деревянных мостов автомобильных лесовозных дорог

The supply of the national economy with forest resources is directly related to transport accessibility, the condition and development of the road network of forest-rich territories. Construction requirements for year-round and seasonal new forest roads are 2.1 and 9.3 ths km per year, respectively. The situation is complicated by the transfer of transport facilities to new heavier live loads. The previously used design shapes of transport structures are outdated and require new engineering solutions. This is especially relevant for wooden bridge structures, which are of primary importance to forest road builders. The research subject is the wooden bridge girder superstructures with spans of 12–18 m undergoing increased road loads compared to the previous ones. The research aims is the development of modern designs of wooden beam superstructures based on the composite girders made of logs, board-bar-dowel-nail blocks and factory-made laminated blocks. The research includes: superstructures with composite girders of logs combined by combdowel joints, a method for calculating superstructures with composite girders, design of a 15-meter experimental superstructure containing composite log girders in joint operation with roadway reinforced concrete slab; new designs of 15–21-meter superstructures with board-bar-dowel-nail blocks A11 and NK-80 for live loads, design procedure and technology of block manufacturing, examples of designed and built bridges with the 15-meter superstructures; designs of multi-ribbed superstructures made of prefabricated transportable one-piece laminated sections containing laminated beams and a multilayer laminated timber slab. The proposed designes with composite girders of logs (beams) and board-nail blocks can be manufactured on the sites and yards of logging organizations using commonly used equipment, local qualified staff and materials. The cost parameters of permanent bridges built in the Omsk region with the use of these designs are 1.5–2 times lower than those of reinforced concrete analogues. The use of these designs will be effective in the pilot method of forestry development. The use of laminated superstructures is related to the modern phase of forest infrastructure development.

Using live stream technology to conduct workplace observation assessment of trainee dental nurses: an evaluation of effectiveness and user experience

Aim/objectiveThis study evaluates the effectiveness and users’ experience of using live stream technology to conduct workplace observation assessments of trainee dental nurses. Information on the usability, accessibility, and general satisfaction of this technological technique were collected.Materials and methodsThis nationwide cross-sectional survey was conducted in Scotland and included one focus group and three online questionnaires with qualitative and quantitative questions. The quantitative responses were described using standard descriptive analysis, while the quantitative data were investigated using thematic analysis.ResultsEighty-one trainee dental nurses, 35 clinicians and 19 assessors participated in this study. Live stream observation was generally well received by the trainee dental nurses and clinicians, who thought that it had helped increase their confidence to perform practical skills. The assessors also stated that overall satisfaction was high, and that live stream observation met their expectations for efficacy. However, several technical challenges, such as network issues were brought up by responders.ConclusionThis study provides evidence that workplace observation assessments can be performed in the future by using live stream technology. However, additional investigation and comparison will aid in determining the most effective way of using this approach and providing feedback to promote learning among dental trainees.

Research on the Design of UAV Relay Charging High-rise Platform for Electrical Equipment Live Detection in Substation

The multi-rotor UAV inspection technology has received extensive attention in the live detection of electrical equipment in substations and has begun to be practically applied. However, due to the short endurance and the characteristics of intermittent operations, the UAV needs to frequently travel between the operational airspace and the cabin, which seriously affects the operational efficiency of the inspection. This paper first introduces the traditional substation electrical equipment live detection technology and then summarizes the application of UAV inspection in the substation electrical equipment live detection. Finally, in view of the shortcomings of the existing technology, this paper proposes a design scheme of a relay-charging high-rise platform for live detection and inspection of electrical equipment in substations. The relay charging high-rise platform can be divided into six parts according to the functional structure: high-altitude apron, UAV landing guidance system, UAV automatic binding system, high insulation strength power supply system, and platform monitoring system. In this paper, the overall structure of the relay charging high-level platform and the technical solutions of each component are described in detail. The technical solution can effectively improve the efficiency and safety of multi-rotor UAV inspection operations for live detection of electrical equipment in substations.

An optimal solution to reduce virtual machine migration SLA using host power

The growing demand for cloud services from users, organizations are planning to build more and more data centers to meet the demand. This is expected to increase energy consumption, which in turn will lead to an increase in operating costs and CO2 emissions. Virtual machine live migration technology can be used to reduce the amount of energy consumed by virtual machines. By doing so, virtual machines can be migrated from one server to another and therefore cause a delay in delivering the services to the users. Service Level Agreement (SLA) violation is one of the important parameters to be considered for better utilization of cloud services. By applying the proposed algorithm, SLA violations will be reduced through the process of selecting the host to which the Virtual Machine will be migrated according to the remaining power of the host, and thus the SLAs will be more enforced in the long run. The proposed algorithm has been implemented in CloudSim. In the comparison of the results achieved with the existing algorithms and the proposed algorithm, it is found that the proposed algorithm is capable of reducing the violation of the SLA by 13.6% when compared to the existing algorithms.

Cellular mechanisms of reverse epithelial curvature in tissue morphogenesis.

Epithelial bending plays an essential role during the multiple stages of organogenesis and can be classified into two types: invagination and evagination. The early stages of invaginating and evaginating organs are often depicted as simple concave and convex curves respectively, but in fact majority of the epithelial organs develop through a more complex pattern of curvature: concave flanked by convex and vice versa respectively. At the cellular level, this is far from a geometrical truism: locally cells must passively adapt to, or actively create such an epithelial structure that is typically composed of opposite and connected folds that form at least one s-shaped curve that we here, based on its appearance, term as "reverse curves." In recent years, invagination and evagination have been studied in increasing cellular detail. A diversity of mechanisms, including apical/basal constriction, vertical telescoping and extrinsic factors, all orchestrate epithelial bending to give different organs their final shape. However, how cells behave collectively to generate reverse curves remains less well-known. Here we review experimental models that characteristically form reverse curves during organogenesis. These include the circumvallate papillae in the tongue, crypt-villus structure in the intestine, and early tooth germ and describe how, in each case, reverse curves form to connect an invaginated or evaginated placode or opposite epithelial folds. Furthermore, by referring to the multicellular system that occur in the invagination and evagination, we attempt to provide a summary of mechanisms thought to be involved in reverse curvature consisting of apical/basal constriction, and extrinsic factors. Finally, we describe the emerging techniques in the current investigations, such as organoid culture, computational modelling and live imaging technologies that have been utilized to improve our understanding of the cellular mechanisms in early tissue morphogenesis.

Live test technology for metal shielding of medium and low voltage power cables in continuous state

Live test technology for metal shielding of medium and low voltage power cables in continuous state

Actual purchases on Instagram Live Shopping: The influence of live shopping engagement and information technology affordance

Live shopping online has been expanded to include social media platforms. This study aimed to determine how the Instagram Live Shopping feature influences buyer engagement and actual buying behaviors.A mixed method approach was applied. An online survey was conducted with 517 respondents, and the data were analyzed using partial least square structural equation modelling. The survey results were then validated via interviews with nine respondents.The results of this study indicated that visibility, metavoicing, shopping guidance, trading, and triggered attending supported the buyers’ feelings of immersion and interactivity but did not entirely support the presence of the seller. Furthermore, the feelings of immersion and presence led to actual buying behaviors.The results of this study may assist e-commerce and/or social commerce application developers in evaluating and implementing features to increase user engagement.

Real-Time Cyber Analytics Data Collection Framework

In cyber security, it is critical that event data is collected in as near real time as possible to enable early detection and response to threats. Performing analytics from event logs stored in databases slows down the response time due to the time cost of database insertion and retrieval operations. The authors present a data collection framework that minimizes the need for long-term storage. Events are buffered in memory, up to a configurable threshold, before being streamed in real time using live streaming technologies. The framework deploys virtualized data collecting agents that ingest data from multiple sources including threat intelligence. The framework enables the correlation of events from various sources, improving detection precision. The authors have tested the framework in a real time, machine-learning-based threat detection system. The results show a time gain of 300 milliseconds in transmission time from event capture to analytics system, compared with storage-based collection frameworks. Threat detection was measured at 95%, which is comparable to the benchmark snort IDS.

Impact of Online Group Psychoeducation and Support Sessions on Receptivity Towards Digital Mental Health Care During the COVID-19 Pandemic: A Pilot Study

While social distancing was crucial to slow the COVID-19 virus, it also contributed to social isolation and emotional strain. This pilot study evaluated the impact of stand-alone psychoeducational group sessions designed to build social connectedness and space for people to learn about mental health during the pandemic. The study examined if offering the stand-alone group sessions increased uptake of and receptivity to additional mental health services. People had access to free, online group psychoeducational sessions offered by a digital mental health platform company. Sessions were offered to (1) employees who had mental health benefits offered through their employer, and to (2) members of the general public. Session formats included discussions, didactic lectures, and workshops, were facilitated by a mental health provider, and used live video conference technology. Topics included race and identity, stress management, coping with political events, relationship issues, and self-compassion. First-time session registrations were tracked from June 2020 to July 2021 on 6723 participants (3717 benefits-eligible employees and 3006 from the general public). Among the employee subsample, 49.5% attended a group session as their first use of any available service on the platform; 52.5% of these employees sought additional services after their first session. In anonymous post-session surveys of employees and members of the general public, 86% of respondents endorsed knowledge increases, 79.5% reported improved understanding of their mental health, 80.3% endorsed gaining actionable steps to improve mental health, 76.5% said that they would consider group sessions in addition to therapy, and 43.5% said that they would consider group sessions instead of therapy. These results suggest that scalable, brief group psychoeducational sessions are a useful conduit to mental health care and have potential to reach people who may not otherwise access available mental health services.

3D Bioprinting with Live Cells

• 3D bioprinting is a means of producing artificial organ replacements. • 3D bioprinting is a power tool for precision medicine for customized need. • Summary of live-cell printing methodologies, applications, and future directions. In recent years, the shortage of available organs for transplant patients has grown exponentially across the globe. Consequently, the healthcare industry is in dire need of artificial substitutes. Many recent research studies and tissue engineering groups have decided to utilize 3D bioprinting to produce these artificial organs. This synthetic organ printing is made possible by advancements in the materials required for the constructs, the printing methodologies used to produce them, and the final physical structures’ varying properties. The cutting-edge research and technology related to 3D and 4D live cell bioprinting have recently allowed researchers to produce multiple types of artificial organs and tissues. These tissues can be utilized for drug screening and organ replacement applications. This article provides an extensive review of all the pertinent 3D live cell bioprinting technologies. First, we describe scaffolding methods and their comparison with the traditional technologies. Second, we explain the 3D bioprinting technology, its evolution, and its multiple types. Moreover, we describe the pros and cons of each bioprinting method. Third, we have discussed the critical bioink properties and their impact on the formation of 3D bioprinting models. In addition, we also describe the mechanical properties of bioprinters. Fourth, we have thoroughly discussed the various types of hydrogels and their properties. Every kind of hydrogel is utilized in specific applications, and we have presented a comprehensive list of its advantages and disadvantages. Fifth, we have discussed various applications of 3D bioprinting technology. We have considered a case study of human organs and elaborated on how bioprinters can revolutionize the organ replacement industry. Finally, we evaluated the possibility of 4D printing in the future organ industry, incorporating temporal factors into the bioprinting process.

Development of Live Attenuated Salmonella Typhimurium Vaccine Strain Using Radiation Mutation Enhancement Technology (R-MET).

Salmonella enterica is a leading cause of food-borne diseases in humans worldwide, resulting in severe morbidity and mortality. They are carried asymptomatically in the intestine or gallbladder of livestock, and are transmitted predominantly from animals to humans via the fecal-oral route. Thus, the best preventive strategy is to preemptively prevent transmission to humans by vaccinating livestock. Live attenuated vaccines have been mostly favored because they elicit both cellular and humoral immunity and provide long-term protective immunity. However, developing these vaccines is a laborious and time-consuming process. Therefore, most live attenuated vaccines have been mainly used for phenotypic screening using the auxotrophic replica plate method, and new types of vaccines have not been sufficiently explored. In this study, we used Radiation-Mutation Enhancement Technology (R-MET) to introduce a wide variety of mutations and attenuate the virulence of Salmonella spp. to develop live vaccine strains. The Salmonella Typhimurium, ST454 strain (ST WT) was irradiated with Cobalt60 gamma-irradiator at 1.5 kGy for 1 h to maximize the mutation rate, and attenuated daughter colonies were screened using in vitro macrophage replication capacity and in vivo mouse infection assays. Among 30 candidates, ATOMSal-L6, with 9,961-fold lower virulence than the parent strain (ST454) in the mouse LD50 model, was chosen. This vaccine candidate was mutated at 71 sites, and in particular, lost one bacteriophage. As a vaccine, ATOMSal-L6 induced a Salmonella-specific IgG response to provide effective protective immunity upon intramuscular vaccination of mice. Furthermore, when mice and sows were orally immunized with ATOMSal-L6, we found a strong protective immune response, including multifunctional cellular immunity. These results indicate that ATOMSal-L6 is the first live vaccine candidate to be developed using R-MET, to the best of our knowledge. R-MET can be used as a fast and effective live vaccine development technology that can be used to develop vaccine strains against emerging or serotype-shifting pathogens.

Case Study: Code of Ethics for Facial Recognition Technology

Facial Recognition Technology (FRT) is a way of identifying an individual by comparing their facial signature to a database of known faces. It has many current uses, and this is only expected to grow due to its many potential and promising applications. However, this technology presents a lot of ethical issues that need to be addressed. This paper examines current literature to find the current ethical issues of FRT such as its usage to infringe on one’s privacy, use an individual’s data without their consent and misidentify individuals. Based on these issues, a code of ethics will be created that will ensure an individual's privacy and data security and minimize the biases and misidentifications in FRT. This code of ethics is applied and assessed via a case study about the usage of live facial recognition technology in the New Zealand Police.

MEDB-76. Evaluating the B7-H3 checkpoint in Medulloblastoma

BACKGROUND: There is currently no curative therapy for recurrent/refractory MB. Novel approaches to MB include immunotherapy, such as targeting the immune checkpoint molecule B7-H3. B7-H3 is implicated in tumor metastasis and is highly expressed in MB. This study explores the effects of genetically knocking down B7-H3 in a murine model of recurrent/refractory medulloblastoma. METHODS: Murine MB cells were transduced with a CRISPR/Cas9 lentivirus to create a B7-H3 knockout. Knockout population was sorted twice via FACS by the AECOM flow cytometry CORE and confirmed by western blot and flow cytometry. Three healthy clones were used in subsequent studies, and compared to the wild type and the scramble control. IncuCyte live imaging technology was used to evaluate spheroid growth. Matrigel Boyden chambers were used to evaluate migration. Bulk RNA-seq was performed by the Yale University Core. RESULTS: B7-H3 knockout was successful in the murine MB model. Morphological differences were noted in the B7-H3 knockout cells. Spheroid formation assays show one of the clones with statistically slower growth kinetics compared to controls. Migration results are pending. RNA seq revealed similar clustering amongst knockouts, separate from controls with an enrichment in genes of morphologic development, WNT signaling and amoeboid migration. CONCLUSIONS: The morphologic changes in the B7-H3 knockouts suggest a potential growth differential. Although in vitro growth assays have shown mixed results regarding the effect of knocking out B7-H3 in spheroid formation, B7-H3 has been more directly implicated in migration and immune signaling. If migration is impaired, this will suggest that B7-H3 enhances malignant and metastatic potential in MB. Functional in vivo immune studies in syngeneic mice will investigate immune mediated effects of B7-H3 knockout in this tumor. If our studies support a role for B7-H3 in the development of MB, it may have important clinical implications, particularly for relapsed patients.