The liquefaction potential of saturated cohesionless deposits in Guwahati city, Assam, was evaluated. The critical cyclic stress ratio required to cause liquefaction and the cyclic stress ratio induced by an earthquake were obtained using the simplified empirical method developed by Seed and Idriss (J soil Mech Found Eng ASCE 97(SM9):1249–1273, 1971, Ground motions and soil liquefaction during earthquakes. Earthquake Engineering Research Institute, Berkeley, CA, 1982) and Seed et al. (J Geotech Eng ASCE 109(3):458–483, 1983, J Geotech Eng ASCE 111(12):1425–1445, 1985) and the Idriss and Boulanger (2004) method. Critical cyclic stress ratio was based on the empirical relationship between standard penetration resistance and cyclic stress ratio. The liquefaction potential was evaluated by determining factor of safety against liquefaction with depth for areas in the city. A soil database from 200 boreholes covering an area of 262 km2 was used for the purpose. A design peak ground acceleration of 0.36 g was used since Guwahati falls in zone V according to the seismic zoning map of India. The results show that 48 sites in Guwahati are vulnerable to liquefaction according to the Seed and Idriss method and 49 sites are vulnerable to liquefaction according to the Idriss and Boulanger method. Results are presented as maps showing zones of levels of risk of liquefaction.