Lipid Profile Of Male Rats Research Articles

Aronia melanocarpa (MICHX.) elliot influences age-dependent changes in the wall of the thoracic aorta and the lipid profile of male rats

Aronia melanocarpa (MICHX.) elliot influences age-dependent changes in the wall of the thoracic aorta and the lipid profile of male rats

BIOLOGICAL EFFECT OF TOMATO JUICE AND PASTE ON HEMOGLOBIN DEFICIENCY IN RATS

Tomato is a good source Phytochemicals and it may be important owning to their paternal use in traditional medicine. Anemia in association With iron deficiency has serious implications in long terms.The Study aimed to evaluate the effect of tomato Juice and Paste alone or with phenylhydrazine (PHZ) on the levels of hemoglobin (Hb), Red blood cells( RBCs) and White blood cells (WBCs) also effect on the levels of Thiobarbituric acid reactive substances (TBARS), glutathione reduced )GSH(, the activities of antioxidant enzymes and lipid profile of male rats 36 male rats were assigned to Six groups for (4) weeks. Feeding period, group (1) –ve control, group (2) treated with juice, group (3) treated with paste, group (4) treat with PHZ, + ve control, group (5) treated with combination of PHZ and juice, group (6) treated with combination of Phz and Paste . Results showed that consumption of Tomato juice and paste group showed improvement of hemoglobin values and had significant decrease in serum lipid profile and Thiobarbituric acid reactive substances (TBARS). Moreover, they showed significant increase in hemoglobin, blood picture and Antioxidant enzymes such as superoxide dismutase, glutathione-peroxidase ,catalase and glutathione S-transferase, compared with control +ve group. The best treatment effect of anemia injured rats group appeared in Tomato juice or paste groups. These results may be attributed to nutritional component and antioxidant activity of Tomato juice and paste. In conclusion, feeding rats with Tomato juice and paste may significantly reduce anemic. Key words, tomato, PHz, CBC, antioxidant enzymes, lipid profile, anemia, rats .

Sudy of theeffects of orchidectomy and testosterone and estradiol administration on lipids profile in male rats

Introduction: Sex steroids have multiple roles in regulating of body lipid metabolism. The purpose of this study was to investigate the effects of orchidectomy and administration of testosterone and estradiol on lipid profile in male rats. Methods: In this experimental study, 40 male rats were divided into groups of 5 animals in each: control, orchidectomized, testosterone or estradiol receiving, orchidectomized testosterone receiving, estradiol receiving, orchidectomized estradiol receiving, sham and olive oil receiving rats. Testosterone enanthate (10µg/kg/day) and estradiol valerate (2µg/kg/day) were injected intraperitoneally. After 7 weeks, blood samples were obtained and serum levels of lipid profile were measured using spectrophotometry method. Data were analyzed using SPSS19 software and ANOVA. Results: Serum level of triglyceride and VLDL significantly decreased in orchidectomized group compared to the control group (P<0.01). Serum LDL and HDL levels were not significantly changed in all groups compared with the control group. Compared to the control group, there was a significant decrease in serum cholesterol levels in orchiectomized (P<0.01), testosterone receiving (P<0.001), estradiol receiving orchiectomized (P<0.01), testosterone receiving orchidectomized (P <0.01) groups. Conclusion: The results of this study indicated that orchidectomy and decreased testosterone results in rapid decrease in cholesterol levels; however, testosterone or estradiol administration did not revert the cholesterol levels to its normal levels. Administration of testosterone causes decreased TG and VLDL levels, but did not significantly change lipid profile.

Effect of Turmeric and Ginger on Lipid Profile in Male Rats Exposed to Oxidative Stress

The present study aimed to investigate the effect of turmeric and ginger on lipid profile of male rats exposed to oxidative stress induced by hydrogen peroxide H2O2 at a concentration of 1% given with consumed drinking water to male rats. Methods: 200 mg/kg from turmeric and ginger were used, and the animals were treatment for 30 days. Results: the results showed a significant increase in cholesterol, triglycerides, low density lipoprotein (LDL), very low density lipoprotein (VLDL), whereas it explained a significant decrease in high density lipoprotein (HDL) of male rats exposed to oxidative stress when compared with control group. the results showed a significant decrease in cholesterol, triglycerides, (LDL), (VLDL), whereas it explained a significant increase in (HDL) of rats treated with turmeric and ginger at dose 200 mg/kg when compared with male rats exposed to oxidative stress.

Grape seed extract role against carbimazole action on thyroid gland and lipid profile in male rats.

Grape seed extract role against carbimazole action on thyroid gland and lipid profile in male rats.

Effect of Whole Quail (Coturnix japonica) Egg Consumption on some Reproductive Parameters and Lipid Profile of Male Albino Rat (Rattus norvegicus)

The present study evaluated the effect of whole egg consumption on the liver, testes, cauda epididymal sperm reserve and lipid profile of male rats. These evaluations were carried out on adult twenty (20) male albino rats, which were randomly selected into four groups of 5 rats each, designated groups A, B, C and D. Group A was the control group and received only equivalent volume of distilled water, while groups B, C and D received 0.25mg/kg, 0.5mg/kg; and 1.0mg/kg body weight of the quail egg respectively. Standard procedures were carried out in the tissue processing, cauda epididymal sperm reserve and in lipid profile determinations. On days 35 and 49, the mean serum total cholesterol value of group D was significantly lower than that of the control group. On day 35, the mean serum low density lipoprotein and high density lipoprotein (LDL and HDL cholesterol) values of all the treatment groups were significantly lower and higher than that of the control group, respectively. However, on days 49 and 63, the mean serum very low density lipoprotein (VLDL cholesterol) and triglyceride values of all the treatment groups were significantly higher than that of the control group. A significant increase in cadual epididymal sperm count (CESR) was recorded on day 63 at the mid and high doses. No obvious pathological lesions were observed in the histomorphology of the testes and liver when compared to the control. Therefore, whole quail egg consumption caused an increase in serum triglyceride and very low density lipoprotein concentration, and also improved fertility. In other words, prolonged consumption of quail egg should be done with caution as it may predispose one to cardiovascular disease.

Effect of Salacca Vinegar Var. Suwaru on Lipid Profile Diabetic Rats

Diabetes mellitus is a group of metabolic diseases with hyperglycemia characteristic that occurs because of abnormalities of insulin secretion. And it becomes one of the major degenerative diseases in the world. The number of studies is conducted to produce hypoglycemic compound and hipolipidemia as an alternative to chemical drugs. One of natural product is salacca vinegar. The purpose of this research is to determine the effect of Salacca vinegar var. Suwaru impact on the diabetic lipid profile of male rats that induced by STZ (Streptozotocin). This reseacrh is conducted by Experimental Post Test Randomized Control Design. Under this research, involves 4 groups, spesifically normal group, diabetic group, diabetic + salacca vinegar 0.4 cc, diabetic + salacca vinegar 0.7 cc. The data were analyzed by ANOVA (Analysis of Variance). The means were assessed for differences through Least Significant Difference (LSD) 0.05. The results showed that Salacca vinegar var. Suwaru with a dose of 0.4 cc/rat/day and 0.7 cc/rat/day influence on lipid profile levels of diabetic rats which affect on decreasing LDL, Trygliceride, total cholesterol and increasing HDL serum plasma diabetic rats.

Temporal Evaluation of Body Composition, Glucose Homeostasis and Lipid Profile of Male Rats Programmed by Maternal Protein Restriction During Lactation

Neonatal protein restriction causes lower body weight and hormonal dysfunctions in 6 months-old rats. In this model, we studied the body composition, glycogen content, serum lipid, serum protein, and hormones related to glucose homeostasis in the offspring during development. At birth, lactating rats were divided into: control dams - fed a normal diet (23% protein) and protein restricted dams - fed a diet with 8% protein. After weaning, pups received normal diet. Offspring were killed at 21, 90, and 180 days-old. Protein restricted offspring showed lower visceral fat (90th day: 14%; 180th day: 19%) and lower total fat (90th day: 16%; 180th day: 14%) that explain their lower body weight. They presented lower glycemia (180th day: 17%), lower insulinemia (21st day: 63%; 180th day: 24%), higher adiponectinemia (21st day: 169%), higher liver glycogen (21st day: 104%), and higher muscle glycogen (180th day: 106%), suggesting a higher insulin sensitivity. The higher serum corticosterone (50%), higher adrenal total catecholamines content (98%) as well as in vitro catecholamine secretion (26%) of adult protein restricted offspring, suggest a programming stimulatory effect upon adrenal gland. They also presented several biochemical changes, such as lower serum total protein, albumin and globulin (21st day: 17, 21, 12%, respectively), higher LDL-c (21st day: 69%), lower triglycerides (21st day: 42%; 90th day: 39%), and lower total cholesterol (180th day: 16%). Thus, maternal protein restriction during lactation induces an energy-protein malnutrition, characterized by an impairment of the pup's protein anabolism and, after weaning, the lower adiposity suggests lower lipogenesis and higher lipolytic activity, probably caused by catecholamine and glucocorticoid action.

Alterations in Serum Lipid Profile of Male Rats by Oral Administration of Aqueous Extract of Fadogia agrestis Stem

Alterations in Serum Lipid Profile of Male Rats by Oral Administration of Aqueous Extract of Fadogia agrestis Stem