Abstract
Diabetes mellitus is a group of metabolic diseases with hyperglycemia characteristic that occurs because of abnormalities of insulin secretion. And it becomes one of the major degenerative diseases in the world. The number of studies is conducted to produce hypoglycemic compound and hipolipidemia as an alternative to chemical drugs. One of natural product is salacca vinegar. The purpose of this research is to determine the effect of Salacca vinegar var. Suwaru impact on the diabetic lipid profile of male rats that induced by STZ (Streptozotocin). This reseacrh is conducted by Experimental Post Test Randomized Control Design. Under this research, involves 4 groups, spesifically normal group, diabetic group, diabetic + salacca vinegar 0.4 cc, diabetic + salacca vinegar 0.7 cc. The data were analyzed by ANOVA (Analysis of Variance). The means were assessed for differences through Least Significant Difference (LSD) 0.05. The results showed that Salacca vinegar var. Suwaru with a dose of 0.4 cc/rat/day and 0.7 cc/rat/day influence on lipid profile levels of diabetic rats which affect on decreasing LDL, Trygliceride, total cholesterol and increasing HDL serum plasma diabetic rats.
Highlights
Diabetes mellitus is one of the major chronic diseases in all populations
It is necessary to study the effect of salacca vinegar on lipid profile in male Wistar rats were conditioned with Streptozotocin-induced diabetic (STZ)
The animals were randomly divided into four groups and each group consists of 5 rats, classified as: normal, diabetic control, diabetic rats treated with salacca vinegar 0.4 cc doses, diabetic rats treated with salacca vinegar 0.7 cc doses
Summary
Diabetes mellitus is one of the major chronic diseases in all populations. In addition to hyperglycemia, the most common feature in diabetes is dyslipidemia, which is contributed to the development of atherosclerosis [1]. Supplement apple vinegar on diabetic rats showed positive results that can lower glucose levels and lipid content in the blood, polyphenols in apple have been shown to lower LDL levels in healthy individuals [1]. Acetic acid can lower triglycerides in rat fed a high-cholesterol diet [4], and the provision of vinegar can lower the glycemic index so as to increase HDL and decrease LDL [5] [6]. Salacca fruit is high in polyphenols might have a positive effect to control of plasma lipids in rat fed a high-cholesterol diet [8]. It is necessary to study the effect of salacca vinegar on lipid profile in male Wistar rats were conditioned with Streptozotocin-induced diabetic (STZ)
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
